AR089233A1 - Determinacion de autoanticuerpos en condiciones de baja conductividad y sensibilidad aumentada - Google Patents

Determinacion de autoanticuerpos en condiciones de baja conductividad y sensibilidad aumentada

Info

Publication number
AR089233A1
AR089233A1 ARP120104707A ARP120104707A AR089233A1 AR 089233 A1 AR089233 A1 AR 089233A1 AR P120104707 A ARP120104707 A AR P120104707A AR P120104707 A ARP120104707 A AR P120104707A AR 089233 A1 AR089233 A1 AR 089233A1
Authority
AR
Argentina
Prior art keywords
autoantibodies
low conductivity
bodies
determination
self
Prior art date
Application number
ARP120104707A
Other languages
English (en)
Inventor
Weber Alfred
Engelmaier Andrea
Schwarz Hans-Peter
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of AR089233A1 publication Critical patent/AR089233A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Métodos para detectar o capturar autoanticuerpos con especificidad por los antígenos amiloides b de baja avidez en una muestra biológica. El antígeno objetivo usado para ensayar los autoanticuerpos de baja avidez de interés se inmoviliza en una fase sólida. La muestra biológica se pone en contacto bajo condiciones de baja conductividad con el antígeno objetivo con el cual los autoanticuerpos tienen afinidad de unión específica. Luego se detecta la unión del antígeno blanco a los autoanticuerpos en la muestra biológica para determinar la presencia o la concentración de los autoanticuerpos de interés.
ARP120104707A 2011-12-13 2012-12-13 Determinacion de autoanticuerpos en condiciones de baja conductividad y sensibilidad aumentada AR089233A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161570211P 2011-12-13 2011-12-13

Publications (1)

Publication Number Publication Date
AR089233A1 true AR089233A1 (es) 2014-08-06

Family

ID=47630506

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120104707A AR089233A1 (es) 2011-12-13 2012-12-13 Determinacion de autoanticuerpos en condiciones de baja conductividad y sensibilidad aumentada

Country Status (14)

Country Link
US (1) US9075069B2 (es)
EP (1) EP2791675B1 (es)
JP (1) JP6333731B2 (es)
KR (1) KR20140104479A (es)
AR (1) AR089233A1 (es)
AU (1) AU2012321074B2 (es)
DK (1) DK2791675T3 (es)
ES (1) ES2685332T3 (es)
HR (1) HRP20181118T1 (es)
HU (1) HUE038441T2 (es)
PL (1) PL2791675T3 (es)
PT (1) PT2791675T (es)
TW (1) TW201339578A (es)
WO (1) WO2013090636A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
EP3022225B1 (en) * 2013-07-19 2021-09-29 Board Of Regents Of the University Of Texas System Transthyretin amyloid-selective and polyreactive catabodies
SI24638A (sl) 2014-02-04 2015-08-31 Univerzitetni kliniÄŤni center Ljubljana Fluorometrična imunska metoda za določanje protiteles proti dvojnoverižni DNA
JP2017528734A (ja) * 2014-08-08 2017-09-28 アレゲーニー・シンガー リサーチ インスティチュート 診断用バイオマーカーとしての抗リンパ球自己抗体
CA2990722C (en) 2015-07-31 2022-07-05 Allegheny-Singer Research Institute Cell-bound complement activation product assays as companion diagnostics for antibody-based drugs
KR20170108203A (ko) 2016-03-16 2017-09-27 주식회사 피플바이오 응집형-형성 폴리펩타이드의 응집형을 검출하는 방법
CN108169303B (zh) * 2017-12-07 2019-08-20 商丘师范学院 基于金属有机框架材料作为信号探针的核酸适配体电化学传感器
US12436148B2 (en) 2018-07-02 2025-10-07 Siemens Healthcare Diagnostics Inc. Direct immunoassay measurement of autoantibodies
JP7268306B2 (ja) * 2018-08-31 2023-05-08 東洋紡株式会社 生体試料中の測定対象物質を免疫学的に測定する方法
JP7356128B2 (ja) * 2019-06-07 2023-10-04 慶應義塾 自己免疫疾患の検出剤となるタンパク質複合体、及びその使用
CN113759107A (zh) * 2021-08-18 2021-12-07 苏州立禾生物医学工程有限公司 生物素标记缓冲液
CN117347616A (zh) * 2022-06-27 2024-01-05 菲鹏生物股份有限公司 稀释剂、捕获试剂、检测试剂盒和测定方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259207A (en) 1979-09-19 1981-03-31 American Hospital Supply Corporation Suspending medium for immunologic reactions
JPS57182168A (en) 1981-05-02 1982-11-09 Mitsubishi Chem Ind Ltd Immunochemical reagent
US5183735A (en) 1989-02-27 1993-02-02 Reaads Medical Products, Inc. Method and diagnostic test kit for detection of anti-dsDNA antibodies
US5194585A (en) * 1989-04-25 1993-03-16 Igen, Inc. Inhibitors of catalytic antibodies
US5981180A (en) 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5763158A (en) 1997-02-06 1998-06-09 The United States Of America As Represented By The Secretary Of The Army Detection of multiple antigens or antibodies
US6958244B2 (en) 2002-04-12 2005-10-25 Bruker Biospin Corp. Low-conductivity buffers for magnetic resonance measurements
ES2661168T3 (es) * 2003-07-12 2018-03-27 Accelerate Diagnostics, Inc. Biodetección sensible y rápida
AU2008286361B2 (en) 2007-08-13 2013-09-26 Takeda Pharmaceutical Company Limited IVIG modulation of chemokines for treatment of multiple sclerosis, Alzheimer's disease, and Parkinson's disease
AU2009222199A1 (en) 2008-02-29 2009-09-11 Baxter Healthcare S.A. Anti-amyloid beta activity of intravenous immunoglobulin (IVIG) in vitro
WO2010101213A1 (ja) 2009-03-05 2010-09-10 デンカ生研株式会社 検査試薬及びそれを用いた被検試料中の被測定物の測定方法
KR20110137379A (ko) * 2009-03-31 2011-12-22 니뽄 다바코 산교 가부시키가이샤 생물학적 시료 중의 ｓｉｔｈ-１의 항체를 검출하는 방법
MX2011012576A (es) 2009-05-27 2012-05-08 Baxter Int Metodo para producir una preparacion altamente concentrada de inmunoglobulina de uso subcutaneo.
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield

Also Published As

Publication number Publication date
AU2012321074A1 (en) 2013-06-27
EP2791675B1 (en) 2018-04-25
EP2791675A1 (en) 2014-10-22
JP6333731B2 (ja) 2018-05-30
HRP20181118T1 (hr) 2018-09-21
PT2791675T (pt) 2018-07-27
WO2013090636A1 (en) 2013-06-20
ES2685332T3 (es) 2018-10-08
AU2012321074B2 (en) 2015-12-03
KR20140104479A (ko) 2014-08-28
DK2791675T3 (da) 2018-07-30
HUE038441T2 (hu) 2018-10-29
TW201339578A (zh) 2013-10-01
JP2015500502A (ja) 2015-01-05
US9075069B2 (en) 2015-07-07
PL2791675T3 (pl) 2018-10-31
US20130149700A1 (en) 2013-06-13

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