ATE403690T1 - POLYMERIC GUANIDINE DERIVATIVES AS CYTOSTATIC DRUGS - Google Patents

POLYMERIC GUANIDINE DERIVATIVES AS CYTOSTATIC DRUGS

Info

Publication number
ATE403690T1
ATE403690T1 AT06020911T AT06020911T ATE403690T1 AT E403690 T1 ATE403690 T1 AT E403690T1 AT 06020911 T AT06020911 T AT 06020911T AT 06020911 T AT06020911 T AT 06020911T AT E403690 T1 ATE403690 T1 AT E403690T1
Authority
AT
Austria
Prior art keywords
polymeric guanidine
guanidine derivatives
cytostatic drugs
cytostatic
polymeric
Prior art date
Application number
AT06020911T
Other languages
German (de)
Inventor
Oskar Schmidt
Original Assignee
Geopharma Produktionsgmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geopharma Produktionsgmbh filed Critical Geopharma Produktionsgmbh
Application granted granted Critical
Publication of ATE403690T1 publication Critical patent/ATE403690T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/024—Polyamines containing oxygen in the form of ether bonds in the main chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

Abstract

Medicament comprising a polymeric guanidine derivative (I) prepared by polycondensation of a guanidinium salt with an alpha ,omega -diamino polyalkylene glycol, is new. ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : None given.
AT06020911T 2003-02-04 2004-01-22 POLYMERIC GUANIDINE DERIVATIVES AS CYTOSTATIC DRUGS ATE403690T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0017403A AT501983B1 (en) 2003-02-04 2003-02-04 Cytostatic drug containing a polymeric guanidine derivative
PCT/AT2004/000023 WO2004069898A1 (en) 2003-02-04 2004-01-22 Polymer guanidine derivatives as a cytostatic medicament

Publications (1)

Publication Number Publication Date
ATE403690T1 true ATE403690T1 (en) 2008-08-15

Family

ID=32831402

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0017403A AT501983B1 (en) 2003-02-04 2003-02-04 Cytostatic drug containing a polymeric guanidine derivative
AT06020911T ATE403690T1 (en) 2003-02-04 2004-01-22 POLYMERIC GUANIDINE DERIVATIVES AS CYTOSTATIC DRUGS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0017403A AT501983B1 (en) 2003-02-04 2003-02-04 Cytostatic drug containing a polymeric guanidine derivative

Country Status (21)

Country Link
US (3) US7820719B2 (en)
EP (2) EP1734064B1 (en)
JP (1) JP4970929B2 (en)
KR (1) KR20050109478A (en)
CN (1) CN100339415C (en)
AT (2) AT501983B1 (en)
AU (1) AU2004208854B2 (en)
BR (1) BRPI0407266A (en)
CA (1) CA2515331A1 (en)
CY (1) CY1107192T1 (en)
DE (2) DE502004005602D1 (en)
DK (1) DK1597302T3 (en)
EA (1) EA011127B1 (en)
ES (1) ES2297371T3 (en)
HR (1) HRP20050697A2 (en)
IL (1) IL170025A (en)
MX (1) MXPA05008267A (en)
PT (1) PT1597302E (en)
SI (1) SI1597302T1 (en)
WO (1) WO2004069898A1 (en)
ZA (1) ZA200505991B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT501983B1 (en) * 2003-02-04 2007-03-15 Geopharma Produktionsgmbh Cytostatic drug containing a polymeric guanidine derivative
AT500998B1 (en) * 2003-03-20 2008-10-15 Geopharma Produktionsgmbh ANTIMICROBIAL ACTIVE MEDICINAL PRODUCT
WO2011008453A2 (en) 2009-06-30 2011-01-20 Monsanto Technology Llc N-phosphonomethylglycine guanidine derivative salts
EP2338342A1 (en) 2009-12-24 2011-06-29 Sebastian Oberwalder Polyuric material with biocidal characteristics
EP2338923B1 (en) 2009-12-24 2017-10-18 Sebastian Oberwalder Polyurethane with a biocidal polyuric material as comonomer
WO2012055568A1 (en) 2010-10-29 2012-05-03 Mindinvest Holdings Ltd. Liposomal drug composition containing a polymeric guanidine derivative
WO2013064161A1 (en) * 2011-11-02 2013-05-10 Mindinvest Holdings Ltd. Polyguanidine silicate and use thereof
AT513858B1 (en) * 2013-01-25 2014-08-15 Sealife Pharma Gmbh New bioactive polymers
EP3810113A4 (en) * 2018-06-21 2022-01-26 UCAR Health GmbH GUANIDINIUM DERIVATIVES AS AN IMMUNITY INDUCING AGENT

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2336605A (en) * 1941-12-29 1943-12-14 Du Pont Pesticide
JPS5587145A (en) * 1978-12-22 1980-07-01 Fuji Photo Film Co Ltd Developing method for silver halide photographic material
JPS59183698A (en) 1983-04-02 1984-10-18 Wako Pure Chem Ind Ltd Quantitative determination of substrate
NL191481C (en) 1983-04-05 1995-08-04 Draegerwerk Ag Anesthetic anesthesia with back breath.
US4891423A (en) * 1989-03-20 1990-01-02 Stockel Richard F Polymeric biguanides
DE4002403A1 (en) * 1990-01-27 1991-08-01 Degussa Prodn. of biocidal polymeric guanidine salts - comprises reaction of di:amine or poly:amine with cyanogen chloride and polymerisation in absence of solvent or in presence of water
DE4002404A1 (en) * 1990-01-27 1991-08-01 Degussa SOLUTIONS OF POLYMER GUANIDINE SALTS WITH INCREASED BIOCIDAL EFFECTIVENESS, METHOD FOR THEIR PRODUCTION AND USE
RU1816769C (en) 1990-12-28 1993-05-23 Московский научно-исследовательский и проектно-изыскательский институт "МосводоканалНИИпроект" Polyoxyalkylene copolymers grafted on polyalkyleneguanidine as surface-active substances and cationic polyelectrolyte
JP3716052B2 (en) * 1996-06-25 2005-11-16 富士写真フイルム株式会社 Processing method of silver halide color photographic light-sensitive material and desilvering processing composition
BR0111163A (en) * 2000-05-11 2003-04-08 P O C Oil Industry Technology Guanidine salt-based biocidal polymers
AT501983B1 (en) * 2003-02-04 2007-03-15 Geopharma Produktionsgmbh Cytostatic drug containing a polymeric guanidine derivative

Also Published As

Publication number Publication date
JP4970929B2 (en) 2012-07-11
EP1734064A2 (en) 2006-12-20
AU2004208854A1 (en) 2004-08-19
CA2515331A1 (en) 2004-08-19
BRPI0407266A (en) 2006-01-31
CN1747984A (en) 2006-03-15
DE502004007805D1 (en) 2008-09-18
AT501983B1 (en) 2007-03-15
DK1597302T3 (en) 2008-04-07
EP1597302A1 (en) 2005-11-23
MXPA05008267A (en) 2006-03-21
CN100339415C (en) 2007-09-26
PT1597302E (en) 2008-03-03
ES2297371T3 (en) 2008-05-01
EA200501245A1 (en) 2006-02-24
ZA200505991B (en) 2006-12-27
CY1107192T1 (en) 2012-11-21
EA011127B1 (en) 2008-12-30
DE502004005602D1 (en) 2008-01-10
IL170025A (en) 2009-09-22
SI1597302T1 (en) 2008-04-30
EP1734064A3 (en) 2006-12-27
US8198333B2 (en) 2012-06-12
US7820719B2 (en) 2010-10-26
HK1088915A1 (en) 2006-11-17
AU2004208854B2 (en) 2010-02-04
HRP20050697A2 (en) 2006-04-30
US20130040388A1 (en) 2013-02-14
KR20050109478A (en) 2005-11-21
AT501983A1 (en) 2006-12-15
US20060034795A1 (en) 2006-02-16
JP2006516575A (en) 2006-07-06
WO2004069898A1 (en) 2004-08-19
US20110076766A1 (en) 2011-03-31
EP1597302B1 (en) 2007-11-28
EP1734064B1 (en) 2008-08-06

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Legal Events

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REN Ceased due to non-payment of the annual fee