ATE550405T1 - Fluoreszenzmarkierungsmittel und fluoreszenzmarkierungsverfahren - Google Patents

Fluoreszenzmarkierungsmittel und fluoreszenzmarkierungsverfahren

Info

Publication number
ATE550405T1
ATE550405T1 AT07832814T AT07832814T ATE550405T1 AT E550405 T1 ATE550405 T1 AT E550405T1 AT 07832814 T AT07832814 T AT 07832814T AT 07832814 T AT07832814 T AT 07832814T AT E550405 T1 ATE550405 T1 AT E550405T1
Authority
AT
Austria
Prior art keywords
zinc oxide
fluorescent marking
oxide nanoparticle
vitro
substance
Prior art date
Application number
AT07832814T
Other languages
English (en)
Inventor
Yasuhisa Fujita
Morihiko Nakamura
Original Assignee
Nat Univ Corp Shimane Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Corp Shimane Univ filed Critical Nat Univ Corp Shimane Univ
Application granted granted Critical
Publication of ATE550405T1 publication Critical patent/ATE550405T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09C—TREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00—Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/02—Compounds of alkaline earth metals or magnesium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09C—TREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00—Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/04—Compounds of zinc
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09C—TREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00—Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/04—Compounds of zinc
    • C09C1/043—Zinc oxide
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/54—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing zinc or cadmium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/56—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing sulfur
    • C09K11/562—Chalcogenides
    • C09K11/565—Chalcogenides with zinc cadmium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/57—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing manganese or rhenium
    • C09K11/572—Chalcogenides
    • C09K11/574—Chalcogenides with zinc or cadmium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/59—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing silicon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/84—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by UV- or VIS- data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/80—Particles consisting of a mixture of two or more inorganic phases
    • C01P2004/82—Particles consisting of a mixture of two or more inorganic phases two phases having the same anion, e.g. both oxidic phases
    • C01P2004/84—Particles consisting of a mixture of two or more inorganic phases two phases having the same anion, e.g. both oxidic phases one phase coated with the other

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Composite Materials (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
AT07832814T 2006-12-01 2007-11-29 Fluoreszenzmarkierungsmittel und fluoreszenzmarkierungsverfahren ATE550405T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006326347 2006-12-01
PCT/JP2007/073114 WO2008066138A1 (en) 2006-12-01 2007-11-29 Fluorescent labeling agent and fluorescent labeling method

Publications (1)

Publication Number Publication Date
ATE550405T1 true ATE550405T1 (de) 2012-04-15

Family

ID=39467925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07832814T ATE550405T1 (de) 2006-12-01 2007-11-29 Fluoreszenzmarkierungsmittel und fluoreszenzmarkierungsverfahren

Country Status (5)

Country Link
US (1) US20110189101A1 (de)
EP (1) EP2093194B1 (de)
JP (1) JP4873576B2 (de)
AT (1) ATE550405T1 (de)
WO (1) WO2008066138A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5062065B2 (ja) * 2007-07-05 2012-10-31 三菱マテリアル株式会社 酸化亜鉛微粒子の製造方法及び該方法により得られた酸化亜鉛微粒子を用いた分散体の製造方法
WO2010050356A1 (ja) 2008-10-30 2010-05-06 国立大学法人島根大学 蛍光標識材料および蛍光標識剤
CZ2009747A3 (cs) * 2009-11-11 2011-05-18 Ceské vysoké ucení technické v Praze Fakulta jaderná a fyzikálne inženýrská Zpusob prípravy nanocásticového scintilátoru na bázi oxidu zinecnatého s vysoce intenzivní luminiscencí
JP5493149B2 (ja) * 2010-06-02 2014-05-14 国立大学法人島根大学 細胞内脂肪球イメージング方法、イメージング用蛍光剤およびイメージング蛍光剤製造方法
JP5989442B2 (ja) * 2012-07-30 2016-09-07 京セラ株式会社 量子ドット粒子およびその製造方法、ならびに太陽電池
CN104535758B (zh) * 2013-06-17 2016-07-27 北京北检·新创源生物技术有限公司 一种将多肽或蛋白质共价偶联至微球上的偶联方法
US9915757B1 (en) 2013-06-24 2018-03-13 The Research Foundation For The State University Of New York Increased thermal stabilization of optical absorbers
US11525779B2 (en) 2016-09-06 2022-12-13 Keio University Method and device for measuring absorbance of aqueous compositions using a substrate having a surface with an adjusted contact angle with water
CN109613200B (zh) * 2018-11-13 2021-07-30 香港科技大学深圳研究院 一种测定纳米锌在不同消化方式海水鱼同化效率的方法
JP7352885B2 (ja) * 2018-12-17 2023-09-29 パナソニックＩｐマネジメント株式会社 修飾粒子の製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018497A2 (en) * 1996-10-28 1998-05-07 Nycomed Imaging As Contrast agents
AU4786797A (en) * 1996-10-28 1998-05-22 Nycomed Imaging As Improvements in or relating to diagnostic/therapeutic agents
AUPP004497A0 (en) * 1997-10-28 1997-11-20 University Of Melbourne, The Stabilized particles
JP4425470B2 (ja) 1998-09-18 2010-03-03 マサチューセッツ インスティテュート オブ テクノロジー 半導体ナノ結晶の生物学的用途
US6251303B1 (en) * 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
AU4305101A (en) * 1999-11-22 2001-06-04 Research Foundation Of The State University Of New York, The Magnetic nanoparticles for selective therapy
EP1374309A1 (de) * 2001-03-30 2004-01-02 The Regents Of The University Of California Verfahren zur herstellung von nanostrukturen und nanoleitungen und daraus hergestellte bauelemente
US7501092B2 (en) * 2001-06-06 2009-03-10 Nomadics, Inc. Manganese doped upconversion luminescence nanoparticles
JP2003028797A (ja) * 2001-07-11 2003-01-29 Hitachi Software Eng Co Ltd 蛍光読み取り装置
US7524630B2 (en) * 2002-04-22 2009-04-28 University Of Florida Research Foundation, Inc. Functionalized nanoparticles and methods of use
JP2004292282A (ja) 2003-03-28 2004-10-21 Mitsubishi Chemicals Corp 酸化亜鉛ナノ粒子及びその製造方法、並びに、その酸化亜鉛ナノ粒子含有組成物及びそれを用いた積層体
JP4072620B2 (ja) 2003-08-08 2008-04-09 国立大学法人島根大学 酸化亜鉛超微粒子および酸化亜鉛超微粒子の製造方法
WO2005060610A2 (en) * 2003-12-11 2005-07-07 The Trustees Of Columbia University In The City Ofnew York Nano-sized particles, processes of making, compositions and uses thereof
US20060263908A1 (en) * 2004-03-08 2006-11-23 Fuji Photo Film Co., Ltd. Fluorescent complex, a fluorescent particle and a fluorescence detection method
JP4727336B2 (ja) * 2004-08-03 2011-07-20 富士フイルム株式会社 蛍光複合体及び蛍光検出方法
JP4072626B2 (ja) 2004-03-29 2008-04-09 独立行政法人産業技術総合研究所 新規生体試料標識用蛍光プローブとその調製法
WO2005123874A1 (ja) * 2004-06-22 2005-12-29 Fujifilm Corporation 蛍光体、蛍光体組成物及び蛍光検出方法
JP4696259B2 (ja) 2004-11-10 2011-06-08 独立行政法人産業技術総合研究所 新規光感受性薬剤及びその製造方法
JP2007023058A (ja) * 2005-07-12 2007-02-01 Fujifilm Holdings Corp 金属酸化物又は金属硫化物ナノ粒子蛍光体を用いる癌検出方法
WO2007136413A2 (en) * 2005-12-22 2007-11-29 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles

Also Published As

Publication number Publication date
WO2008066138A1 (en) 2008-06-05
EP2093194A1 (de) 2009-08-26
JP4873576B2 (ja) 2012-02-08
US20110189101A1 (en) 2011-08-04
JPWO2008066138A1 (ja) 2010-03-11
EP2093194B1 (de) 2012-03-21
EP2093194A4 (de) 2010-03-24

Similar Documents

Publication Publication Date Title
ATE550405T1 (de) Fluoreszenzmarkierungsmittel und fluoreszenzmarkierungsverfahren
ES2525647T3 (es) Película imprimible
EP2000512A3 (de) Verlackte Monoazopigment-Partikel in Nanogröße
ATE423575T1 (de) Zusammensetzungen von magnetischen partikeln mit gem-biphosphonate derivaten beschichtet
WO2010008519A3 (en) In vitro diagnostic markers comprising carbon nanoparticles and kits
AU2003216939A1 (en) Composition for surface treatment of paper
ATE423174T1 (de) Uv-härtbare beschichtungszusammensetzungen und deren verwendung
WO2010039897A3 (en) Nanocrystals with functional ligands
DE602006015908D1 (de) Mikrokugeln mit fluoreszente und magnetische eigenschaften
WO2008140624A3 (en) Methods and compositions related to hybird nanoparticles
AR047586A1 (es) Una composicion de recubrimiento para la formacion de una capa inorganica sobre la superficie de un substrato
WO2008060734A3 (en) Nanoparticle compositions
TW200641056A (en) UV-curable resin composition, UV-curable paint and coated article
UA91243C2 (ru) Металлическая основа с покрытием на основе эпоксидной смолы, способ нанесения покрытия, система двухслойного покрытия и применение
EP1973110A3 (de) Winzige Struktur und Informationsaufzeichnungsmedium
WO2007050984A3 (en) Fluorescent carbon nanoparticles
WO2009053876A3 (en) Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging
WO2008029070A8 (fr) Poudre autoadherente haute performance a base de polyamide sans promoteur d'adhesion
BRPI0508997A (pt) microcamada com siloxanas
BRPI0518234A2 (pt) revestimentos carregados de Água de auto-reticulaÇço
ATE227760T1 (de) Mit nanopartikeln modifizierte bindemittel für überzugsmittel und deren verwendung
CN101735817B (zh) 一种印痕提取纳米荧光粉的制备方法
EP1674093A4 (de) Verfahren zur kontrolle der teilchengrösse von retinolsäure-nanoteilchen mit einer beschichtung aus polyvalentem anorganischem metallsalz und mit dem kontrollverfahren erhaltene nanoteilchen
WO2008152891A1 (ja) 近赤外発光蛍光体ナノ粒子、その製造方法、それを用いた生体物質標識剤
WO2005109515A3 (en) System and method for making nanoparticles with controlled emission properties