BG34181A3 - Method for obtaining antigene patent medicine - Google Patents

Method for obtaining antigene patent medicine

Info

Publication number
BG34181A3
BG34181A3 BG034303A BG3430376A BG34181A3 BG 34181 A3 BG34181 A3 BG 34181A3 BG 034303 A BG034303 A BG 034303A BG 3430376 A BG3430376 A BG 3430376A BG 34181 A3 BG34181 A3 BG 34181A3
Authority
BG
Bulgaria
Prior art keywords
antigenic protein
antigene
obtaining
patent medicine
microvesicles
Prior art date
Application number
BG034303A
Other languages
Bulgarian (bg)
Inventor
June Almeida
David Edwards
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG34181A3 publication Critical patent/BG34181A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Метод за получаване на антигенен препарат, съдържащ липозоми и антигенен протеин, характеризиращ се с това, че липидът, от който са съставени липозомите се разклаща във водна среда до образуване на микровезикули, които след това се разклащат в присъствие на антигенен протеин, при което антигенният протеин се свързва с външната повърхност на липидния двоен слой на микровезикулите, като в даден случай за свързване на антигенния протеин с външната повърхност на липидния двоен слой на микровезикулите се разклаща смес от липид, водна среда и антигенен протеин. Автентните претенции са формулирани в 5 точки.A method for preparing an antigenic preparation containing liposomes and an antigenic protein, characterized in that the lipid from which the liposomes are composed is shaken in an aqueous medium until microvesicles are formed, which are then shaken in the presence of an antigenic protein, wherein the antigenic protein binds to the outer surface of the lipid bilayer of the microvesicles, in some case a mixture of lipid, aqueous medium and antigenic protein is shaken to bind the antigenic protein to the outer surface of the lipid bilayer of the microvesicles. Authentic claims are formulated in 5 points.

BG034303A 1975-09-29 1976-09-28 Method for obtaining antigene patent medicine BG34181A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB39857/75A GB1564500A (en) 1975-09-29 1975-09-29 Biological preparations

Publications (1)

Publication Number Publication Date
BG34181A3 true BG34181A3 (en) 1983-07-15

Family

ID=10411873

Family Applications (1)

Application Number Title Priority Date Filing Date
BG034303A BG34181A3 (en) 1975-09-29 1976-09-28 Method for obtaining antigene patent medicine

Country Status (15)

Country Link
JP (1) JPS5244228A (en)
AU (1) AU514848B2 (en)
BE (1) BE846681A (en)
BG (1) BG34181A3 (en)
CA (1) CA1079634A (en)
DD (1) DD127598A5 (en)
DE (1) DE2643641A1 (en)
ES (1) ES451923A1 (en)
FR (1) FR2325387A1 (en)
GB (1) GB1564500A (en)
HU (1) HU176180B (en)
NL (1) NL7610736A (en)
PL (1) PL103082B1 (en)
SE (1) SE7610708L (en)
ZA (1) ZA765817B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148876A (en) 1975-09-29 1979-04-10 Burroughs Wellcome Co. Biological preparations
US4196191A (en) 1975-09-29 1980-04-01 Burroughs Wellcome Co. Biological preparations
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2420545A1 (en) * 1978-03-20 1979-10-19 Anvar NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
US4201767A (en) * 1978-11-08 1980-05-06 Merck & Co., Inc. Viral liposome particle
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
HU184141B (en) * 1979-12-27 1984-07-30 Human Oltoanyagtermelo Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
DE3173713D1 (en) * 1980-09-05 1986-03-20 Frappier Armand Inst Formation of an immunosome exclusively made of viral antigens reconstituted on an artificial membrane
FR2543018B1 (en) * 1983-03-22 1985-07-26 Oreal PROCESS FOR THE PREPARATION OF LIPID VESICLES BY SPRAYING SOLVENTS
IT1238343B (en) * 1989-10-16 1993-07-13 Cesalpino Andrea Fond PROCEDURE FOR THE PREPARATION OF VACCINES CAPABLE OF GENERATING NOT ONLY THE IMMUNE RESPONSE OF T HELPER LYMPHOCYTES, BUT ALSO AN EFFECTIVE RESPONSE OF CYTOTOXIC T LYMPHOCYTES, AND VACCINES WITH THESE CHARACTERISTICS
RU94040856A (en) * 1992-03-03 1996-08-20 Дайити Фармасьютикал Ко. Vaccine for oral administration
US6096291A (en) * 1996-12-27 2000-08-01 Biovector Therapeutics, S.A. Mucosal administration of substances to mammals
AU2014368594B2 (en) * 2013-12-19 2020-03-05 Janssen Vaccines & Prevention B.V. Improved formulations for virosomes

Also Published As

Publication number Publication date
DD127598A5 (en) 1977-10-05
JPS5244228A (en) 1977-04-07
CA1079634A (en) 1980-06-17
ZA765817B (en) 1978-05-30
AU1816476A (en) 1978-04-06
GB1564500A (en) 1980-04-10
BE846681A (en) 1977-03-28
SE7610708L (en) 1977-03-30
FR2325387A1 (en) 1977-04-22
PL103082B1 (en) 1979-05-31
ES451923A1 (en) 1977-08-16
DE2643641A1 (en) 1977-04-14
AU514848B2 (en) 1981-03-05
HU176180B (en) 1980-12-28
FR2325387B1 (en) 1980-06-27
NL7610736A (en) 1977-03-31

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