BR112022019338A2 - Tratamento preventivo de enxaqueca - Google Patents

Tratamento preventivo de enxaqueca

Info

Publication number
BR112022019338A2
BR112022019338A2 BR112022019338A BR112022019338A BR112022019338A2 BR 112022019338 A2 BR112022019338 A2 BR 112022019338A2 BR 112022019338 A BR112022019338 A BR 112022019338A BR 112022019338 A BR112022019338 A BR 112022019338A BR 112022019338 A2 BR112022019338 A2 BR 112022019338A2
Authority
BR
Brazil
Prior art keywords
preventive treatment
migraine
migraine preventive
rimegepant
pharmaceutical compositions
Prior art date
Application number
BR112022019338A
Other languages
English (en)
Inventor
Coric Vladimir
Croop Robert
Original Assignee
Biohaven Pharmaceutical Ireland Dac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohaven Pharmaceutical Ireland Dac filed Critical Biohaven Pharmaceutical Ireland Dac
Publication of BR112022019338A2 publication Critical patent/BR112022019338A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

TRATAMENTO PREVENTIVO DE ENXAQUECA. A presente invenção refere-se a métodos para o tratamento preventivo de enxaqueca, administrando a um paciente em necessidade do mesmo rimegepant ou um sal farmaceuticamente aceitável do mesmo. Composições farmacêuticas compreendendo rimegepant e kits que incluem as composições farmacêuticas e instruções também são divulgadas.
BR112022019338A 2020-03-29 2021-03-29 Tratamento preventivo de enxaqueca BR112022019338A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063001341P 2020-03-29 2020-03-29
US202063111138P 2020-11-09 2020-11-09
US202063125247P 2020-12-14 2020-12-14
PCT/US2021/024551 WO2021202321A1 (en) 2020-03-29 2021-03-29 Preventative treatment of migraine

Publications (1)

Publication Number Publication Date
BR112022019338A2 true BR112022019338A2 (pt) 2022-12-06

Family

ID=77929752

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022019338A BR112022019338A2 (pt) 2020-03-29 2021-03-29 Tratamento preventivo de enxaqueca

Country Status (11)

Country Link
US (1) US20230321066A1 (pt)
EP (1) EP4125899A4 (pt)
JP (1) JP2023533634A (pt)
KR (1) KR20230015324A (pt)
CN (1) CN115697335A (pt)
AU (1) AU2021247101A1 (pt)
BR (1) BR112022019338A2 (pt)
CA (1) CA3176432A1 (pt)
IL (1) IL296872A (pt)
MX (1) MX2022012001A (pt)
WO (1) WO2021202321A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7764620B2 (ja) * 2022-03-10 2025-11-05 エンザイマスター（ニンポー）バイオエンジニアリング カンパニー・リミテッド ウブロゲパント中間体を合成するための生体触媒及びその合成方法
CN118717761A (zh) * 2024-05-27 2024-10-01 复旦大学 瑞美吉泮在制备治疗/预防阿尔茨海默病药物中的应用
CN120733002B (zh) * 2025-09-03 2025-11-25 华中科技大学同济医学院附属同济医院 Cgrp受体小分子拮抗剂在制备治疗嗜酸性慢性鼻窦炎伴鼻息肉的药品中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3582755A4 (en) * 2017-02-15 2020-12-23 Molecular Infusions, LLC PREPARATIONS
US11400136B2 (en) * 2017-06-19 2022-08-02 President And Fellows Of Harvard College Methods and compositions for treating a microbial infection
MX2020009856A (es) * 2018-03-25 2020-10-08 Biohaven Pharm Holding Co Ltd Rimegepant para trastornos relacionados con el peptido relacionado con el gen para calcitonina (cgrp).
TW202535450A (zh) * 2018-07-05 2025-09-16 愛爾蘭商歐樂根製藥國際有限公司 Cgrp拮抗劑及梭菌衍生物之組合療法
WO2021173936A1 (en) * 2020-02-27 2021-09-02 Biohaven Pharmaceutical Holding Company Ltd. Oral fast-dispersing dosage form of rimegepant

Also Published As

Publication number Publication date
IL296872A (en) 2022-11-01
KR20230015324A (ko) 2023-01-31
CA3176432A1 (en) 2021-10-07
MX2022012001A (es) 2022-10-21
US20230321066A1 (en) 2023-10-12
JP2023533634A (ja) 2023-08-04
WO2021202321A1 (en) 2021-10-07
AU2021247101A1 (en) 2022-11-17
EP4125899A1 (en) 2023-02-08
EP4125899A4 (en) 2024-06-12
CN115697335A (zh) 2023-02-03

Similar Documents

Publication Publication Date Title
ZA202204929B (en) Rimegepant for cgrp related disorders
BR112021009595A2 (pt) Terapia de combinação incluindo um inibidor de krasg12c e um ou mais agentes farmaceuticamente ativos adicionais para o tratamento de cânceres
BR112022000019A2 (pt) Composto da fórmula, composição farmacêutica e método de tratamento de câncer
BR112021017350A2 (pt) Combinação de conjugado de anticorpo-derivado de pirrolobenzodiazepina e inibidor de parp
MX393855B (es) Terapia de combinación que comprende un inhibidor de raf y trametinib
BR112018005454A2 (pt) administração de potencializadores de cftr deuterados
BR112021023347A2 (pt) Compostos de pirrolidina
BR112022024120A2 (pt) Derivado de piridina-pirimidina, método de preparação do mesmo e uso farmacêutico do mesmo
BR112015029491A2 (pt) derivados de imidazopirrolidinona e seu uso no tratamento de doença
BR112019008431A2 (pt) aplicação de (s)-norcetamina e sal da mesma como fármaco
BR112015011497A2 (pt) composto, formulação farmacêutica, produto de combinação, e, método de tratamento de uma doença
BR112014000240A2 (pt) derivados de benzilamina como inibidores de calicreína plasmática
BR112015014458A2 (pt) derivados de manose para o tratamento de infecções bacterianas
BR112022019338A2 (pt) Tratamento preventivo de enxaqueca
MY195194A (en) Substituted Indoline Derivatives as Dengue Viral Replication Inhibitors
BR112013020586A2 (pt) Uso de células derivadas de tecido do cordão umbilical
BR112018015718A2 (pt) utilização de estimuladores de sgc para o tratamento de esteato-hepatite não alcoólica (nash)
BR112016027043A8 (pt) combinação, composição farmacêutica compreendendo glucocorticoide e edo-s101, kit e uso no tratamento de câncer
MX2023014492A (es) Compuestos utiles en la terapia para el vih.
BR112014023423A2 (pt) terapia de combinação
BR112019018615A2 (pt) compostos antimicrobianos, composições e usos dos mesmos
BR112021011325A2 (pt) Derivados de rapamicina
JOP20200242A1 (ar) مركبات البلاديينوليد واستخداماتها
BR112022022452A2 (pt) Inibidores de il4i1 e métodos de uso
BR112019005456A2 (pt) composição farmacêutica e método para tratamento de esteatose hepática não alcoólica

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: PFIZER IRELAND PHARMACEUTICALS (IE)

B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]