BR9206463A - Processos para a seleção separação e fusão de células - Google Patents
Processos para a seleção separação e fusão de célulasInfo
- Publication number
- BR9206463A BR9206463A BR9206463A BR9206463A BR9206463A BR 9206463 A BR9206463 A BR 9206463A BR 9206463 A BR9206463 A BR 9206463A BR 9206463 A BR9206463 A BR 9206463A BR 9206463 A BR9206463 A BR 9206463A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- cells
- fusion
- processes
- cell separation
- Prior art date
Links
- 230000004927 fusion Effects 0.000 title abstract 2
- 238000000926 separation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000004720 dielectrophoresis Methods 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Sustainable Development (AREA)
- Hematology (AREA)
- Electromagnetism (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Plant Pathology (AREA)
- Electrochemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPK821391 | 1991-09-05 | ||
| PCT/AU1992/000473 WO1993005166A1 (en) | 1991-09-05 | 1992-09-04 | Methods for the selection, separation and fusion of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9206463A true BR9206463A (pt) | 1995-12-12 |
Family
ID=3775670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9206463A BR9206463A (pt) | 1991-09-05 | 1992-09-04 | Processos para a seleção separação e fusão de células |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5589047A (pt) |
| EP (1) | EP0607178B1 (pt) |
| JP (1) | JP3104995B2 (pt) |
| KR (1) | KR100281177B1 (pt) |
| AT (1) | ATE216426T1 (pt) |
| AU (1) | AU661037B2 (pt) |
| BR (1) | BR9206463A (pt) |
| CA (1) | CA2117070A1 (pt) |
| DE (1) | DE69232560T2 (pt) |
| MX (1) | MX9205086A (pt) |
| NZ (1) | NZ244216A (pt) |
| WO (1) | WO1993005166A1 (pt) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795457A (en) * | 1990-01-30 | 1998-08-18 | British Technology Group Ltd. | Manipulation of solid, semi-solid or liquid materials |
| US6331274B1 (en) | 1993-11-01 | 2001-12-18 | Nanogen, Inc. | Advanced active circuits and devices for molecular biological analysis and diagnostics |
| US6225059B1 (en) | 1993-11-01 | 2001-05-01 | Nanogen, Inc. | Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics |
| US6129828A (en) | 1996-09-06 | 2000-10-10 | Nanogen, Inc. | Apparatus and methods for active biological sample preparation |
| WO1995023020A1 (de) * | 1994-02-24 | 1995-08-31 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Formen von mikropartikeln in elktrischen feldkäfigen |
| US6071394A (en) | 1996-09-06 | 2000-06-06 | Nanogen, Inc. | Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis |
| DE19859459A1 (de) * | 1998-12-22 | 2000-06-29 | Evotec Biosystems Ag | Mikrosysteme zur Zellpermeation und Zellfusion |
| US6537433B1 (en) * | 2000-03-10 | 2003-03-25 | Applera Corporation | Methods and apparatus for the location and concentration of polar analytes using an alternating electric field |
| GB2361479A (en) * | 2000-04-11 | 2001-10-24 | Secr Defence | Electric-field structuring of composite materials |
| US6661575B1 (en) * | 2000-10-31 | 2003-12-09 | Sergey A. Yakovenko | Methods and apparata for micromanipulation of micro-and nanoparticles |
| US7101703B2 (en) * | 2001-03-09 | 2006-09-05 | Cornell Research Foundation, Inc. | Electrofusion microelectrode |
| DE10116211A1 (de) * | 2001-03-27 | 2002-10-10 | Eppendorf Ag | Kammer zur Behandlung von in einer Suspension enthaltenen Zellen im elektrischen Feld |
| JP4217618B2 (ja) * | 2001-08-31 | 2009-02-04 | サイト パルス サイエンシズ、インコーポレイテッド | 細胞融合のためのノンリニアーな振幅の誘電泳動用波形 |
| US6750661B2 (en) * | 2001-11-13 | 2004-06-15 | Caliper Life Sciences, Inc. | Method and apparatus for controllably effecting samples using two signals |
| US20030119057A1 (en) * | 2001-12-20 | 2003-06-26 | Board Of Regents | Forming and modifying dielectrically-engineered microparticles |
| US6887362B2 (en) * | 2002-02-06 | 2005-05-03 | Nanogen, Inc. | Dielectrophoretic separation and immunoassay methods on active electronic matrix devices |
| CA2484629A1 (en) * | 2002-05-31 | 2003-12-11 | Apollo Life Sciences Pty Limited | Electrofusion of cells and apparatus therefore |
| US20060199168A1 (en) * | 2002-05-31 | 2006-09-07 | Wills Ivan N | Cell recovery |
| US20040003679A1 (en) * | 2002-07-05 | 2004-01-08 | David Ide | Apparatus and method for in vitro recording and stimulation of cells |
| AU2003302333A1 (en) * | 2002-12-20 | 2004-07-22 | Board Of Regents, The University Of Texas System | Methods and apparatus for electrosmear analysis |
| GB0303305D0 (en) * | 2003-02-12 | 2003-03-19 | Secr Defence | Apparatus for collecting particles |
| EP1702065B1 (en) | 2003-12-01 | 2017-02-15 | Cellectis | Non-uniform electric field chamber for cell fusion |
| WO2005075958A1 (de) * | 2004-02-04 | 2005-08-18 | Evotec Technologies Gmbh | Mikrofluidisches system und zugehöriges betriebsverfahren |
| US7390388B2 (en) * | 2004-03-25 | 2008-06-24 | Hewlett-Packard Development Company, L.P. | Method of sorting cells on a biodevice |
| US7160425B2 (en) * | 2004-03-25 | 2007-01-09 | Hewlett-Packard Development Company, L.P. | Cell transporter for a biodevice |
| US7390387B2 (en) * | 2004-03-25 | 2008-06-24 | Hewlett-Packard Development Company, L.P. | Method of sorting cells in series |
| EP2270130B1 (en) | 2005-06-13 | 2020-04-29 | Tosoh Corporation | Cell fusion device, and method for cell fusion using the same |
| US8262885B2 (en) * | 2005-11-18 | 2012-09-11 | President And Fellows Of Harvard College | Dielectrophoretic tweezers apparatus and methods |
| US7915044B2 (en) * | 2005-12-22 | 2011-03-29 | Cornell Research Foundation, Inc. | Electrofusion microelectrode and methods of using it to manipulate cells and/or cellular components |
| ITMI20061063A1 (it) * | 2006-05-31 | 2007-12-01 | Mindseeds Lab S R L | Metrodo e apparato pe rla selezione e la modifica di singole cellule e loro piccoli aggregati |
| US9018019B2 (en) * | 2006-10-04 | 2015-04-28 | President And Fellows Of Harvard College | Engineered conductive polymer films to mediate biochemical interactions |
| JP2010518857A (ja) | 2007-02-23 | 2010-06-03 | アドバンスド セル テクノロジー, インコーポレイテッド | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| US8021532B2 (en) * | 2008-02-26 | 2011-09-20 | President And Fellows Of Harvard College | Dielectrophoretic tweezers apparatus and methods |
| JP2009273459A (ja) * | 2008-04-15 | 2009-11-26 | Tosoh Corp | 細胞選別装置、およびそれを用いた細胞選別方法 |
| JP5515094B2 (ja) * | 2009-10-30 | 2014-06-11 | 独立行政法人海洋研究開発機構 | 増殖可能な動物細胞の調製方法 |
| EP2646830B1 (en) | 2010-12-03 | 2016-04-13 | Cellply S.R.L. | Rapid screening of monoclonal antibodies |
| CN104792845A (zh) * | 2014-08-07 | 2015-07-22 | 中国科学院微电子研究所 | 传感装置 |
| WO2016044271A2 (en) | 2014-09-15 | 2016-03-24 | Children's Medical Center Corporation | Methods and compositions to increase somatic cell nuclear transfer (scnt) efficiency by removing histone h3-lysine trimethylation |
| EP3258240B1 (en) | 2016-06-14 | 2023-06-07 | Cellply S.R.L. | Screening kit and methods |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018662A (en) * | 1975-01-03 | 1977-04-19 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Method and apparatus for simultaneous quantitative analysis of several constituents in a sample |
| DD136895A1 (de) * | 1978-06-02 | 1979-08-01 | Roland Glaser | Verfahren zur trennung von biologischen teilchengemischen durch dielektrophorese |
| US4326934A (en) * | 1979-12-31 | 1982-04-27 | Pohl Herbert A | Continuous dielectrophoretic cell classification method |
| US4578167A (en) * | 1982-09-28 | 1986-03-25 | Biofusion, Inc. | Cell fusion |
| US4441972A (en) * | 1983-04-08 | 1984-04-10 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US5001056A (en) * | 1984-06-08 | 1991-03-19 | The Johns Hopkins University | Preparation of monoclonal antibodies |
| US4561961A (en) * | 1984-07-27 | 1985-12-31 | Biotronics | Cooled microscope slide and electrode apparatus for use in live cell fusion system |
| DE8504192U1 (de) * | 1985-02-15 | 1985-08-01 | GCA Corp., Bedford, Mass. | Vorrichtung zur Elektrofusion von Zellen |
| JPH074216B2 (ja) * | 1986-08-20 | 1995-01-25 | 株式会社アドバンス | 電気細胞融合方法 |
| US4970154A (en) * | 1987-10-09 | 1990-11-13 | Baylor College Of Medicine | Method for inserting foreign genes into cells using pulsed radiofrequency |
| DD285992A5 (de) * | 1989-07-20 | 1991-01-10 | Akad Wissenschaften Ddr | Zellfusionsverfahren |
| GB9002092D0 (en) * | 1990-01-30 | 1990-03-28 | P & B Sciences Ltd | Manipulation of solid,semi-solid or liquid materials |
| JP3099049B2 (ja) * | 1992-07-29 | 2000-10-16 | 農林水産省果樹試験場長 | 電気的細胞融合及び電気的核酸導入のための大量処理用電極 |
-
1992
- 1992-01-17 JP JP04504761A patent/JP3104995B2/ja not_active Expired - Lifetime
- 1992-09-04 AT AT92919530T patent/ATE216426T1/de not_active IP Right Cessation
- 1992-09-04 BR BR9206463A patent/BR9206463A/pt not_active IP Right Cessation
- 1992-09-04 NZ NZ244216A patent/NZ244216A/en not_active IP Right Cessation
- 1992-09-04 KR KR1019940700737A patent/KR100281177B1/ko not_active Expired - Fee Related
- 1992-09-04 EP EP92919530A patent/EP0607178B1/en not_active Expired - Lifetime
- 1992-09-04 DE DE69232560T patent/DE69232560T2/de not_active Expired - Fee Related
- 1992-09-04 AU AU25620/92A patent/AU661037B2/en not_active Ceased
- 1992-09-04 MX MX9205086A patent/MX9205086A/es not_active IP Right Cessation
- 1992-09-04 WO PCT/AU1992/000473 patent/WO1993005166A1/en not_active Ceased
- 1992-09-04 CA CA002117070A patent/CA2117070A1/en not_active Abandoned
- 1992-09-04 US US08/204,253 patent/US5589047A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0607178B1 (en) | 2002-04-17 |
| WO1993005166A1 (en) | 1993-03-18 |
| ATE216426T1 (de) | 2002-05-15 |
| EP0607178A4 (en) | 1995-12-27 |
| NZ244216A (en) | 1994-06-27 |
| EP0607178A1 (en) | 1994-07-27 |
| MX9205086A (es) | 1993-05-01 |
| JPH06510193A (ja) | 1994-11-17 |
| JP3104995B2 (ja) | 2000-10-30 |
| AU2562092A (en) | 1993-04-05 |
| US5589047A (en) | 1996-12-31 |
| DE69232560T2 (de) | 2003-01-16 |
| DE69232560D1 (de) | 2002-05-23 |
| KR100281177B1 (ko) | 2001-04-02 |
| AU661037B2 (en) | 1995-07-13 |
| CA2117070A1 (en) | 1993-03-18 |
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