BR9612307A - Derivados de 1-(1,2-piperidinil di-substituído)-4-(mizadol fundido)-piperidina - Google Patents

Derivados de 1-(1,2-piperidinil di-substituído)-4-(mizadol fundido)-piperidina

Info

Publication number: BR9612307A
Authority: BR; Brazil
Prior art keywords: mizadol; piperidinyl; piperidine; fused; derivatives
Prior art date: 1995-12-27

Application number

BR9612307A

Other languages

English (en)

Inventor

Frans Eduard Jassens

Joseph Elisabeth Leenaertes

Yves Emiel Maria Va Roosbroeck

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-27

Filing date

1996-12-20

Publication date

1999-07-13

1996-12-20 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1999-07-13 Publication of BR9612307A publication Critical patent/BR9612307A/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Immunology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Otolaryngology (AREA)
Biotechnology (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BR9612307A 1995-12-27 1996-12-20 Derivados de 1-(1,2-piperidinil di-substituído)-4-(mizadol fundido)-piperidina BR9612307A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95203652		1995-12-27
PCT/EP1996/005885 WO1997024356A1 (en)	1995-12-27	1996-12-20	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

Publications (1)

Publication Number	Publication Date
BR9612307A true BR9612307A (pt)	1999-07-13

Family

ID=8221024

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9612307A BR9612307A (pt)	1995-12-27	1996-12-20	Derivados de 1-(1,2-piperidinil di-substituído)-4-(mizadol fundido)-piperidina

Country Status (29)

Country	Link
US (1)	US6251894B1 (pt)
EP (1)	EP0843679B1 (pt)
JP (1)	JP4097043B2 (pt)
KR (1)	KR100485147B1 (pt)
CN (1)	CN1066733C (pt)
AR (2)	AR005278A1 (pt)
AT (1)	ATE208392T1 (pt)
AU (1)	AU716071B2 (pt)
BR (1)	BR9612307A (pt)
CA (1)	CA2238817C (pt)
CY (1)	CY2271B1 (pt)
CZ (1)	CZ295861B6 (pt)
DE (1)	DE69616802T2 (pt)
DK (1)	DK0843679T3 (pt)
EA (1)	EA001374B1 (pt)
ES (1)	ES2167619T3 (pt)
HU (1)	HU229766B1 (pt)
IL (2)	IL124642A (pt)
MY (1)	MY117680A (pt)
NO (1)	NO310916B1 (pt)
NZ (1)	NZ325845A (pt)
PL (1)	PL183767B1 (pt)
PT (1)	PT843679E (pt)
SI (1)	SI0843679T1 (pt)
SK (1)	SK283540B6 (pt)
TR (1)	TR199801210T2 (pt)
TW (1)	TW382017B (pt)
WO (1)	WO1997024356A1 (pt)
ZA (1)	ZA9610889B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW527186B (en) *	1996-03-19	2003-04-11	Janssen Pharmaceutica Nv	Fused imidazole derivatives as multidrug resistance modulators
ATE233104T1 (de)	1997-09-18	2003-03-15	Janssen Pharmaceutica Nv	Kondensierte imidazolderivate zur erhöhung der oralen bioverfügbarkeit von pharmazeutika
BR9916371A (pt) *	1998-12-19	2001-09-18	Janssen Pharmaceutica Nv	Composto de espiro anti-histamìnico
WO2001030348A1 (en) *	1999-10-25	2001-05-03	Janssen Pharmaceutica N.V.	Use of substance p antagonists for influencing the circadian timing system
CA2448735C (en)	2001-06-12	2008-10-28	Janssen Pharmaceutica N.V.	Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine
US20030083345A1 (en) *	2001-07-10	2003-05-01	Torsten Hoffmann	Method of treatment and/or prevention of brain, spinal or nerve injury
AU2002356715B2 (en) *	2001-11-23	2008-05-15	Janssen Pharmaceutica N.V.	The use of anti-histaminics for acute reduction of elevated intracranial pressure
EP1457493A4 (en) *	2001-12-10	2005-11-30	Kyorin Seiyaku Kk	CONDENSED, BICYCLIC PYRIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS
DE60300683T2 (de) *	2002-01-16	2006-04-27	Janssen Pharmaceutica N.V.	Prucaloprid-n-oxid
ATE427310T1 (de)	2002-01-18	2009-04-15	Kyorin Seiyaku Kk	Kondensierte bicyclische pyrimidinderivate
KR20040099367A (ko)	2002-03-26	2004-11-26	교린 세이야꾸 가부시키 가이샤	타키키닌 수용체 길항제로서의 축합 바이사이클릭 피리딘 유도체
WO2004056805A1 (en) *	2002-12-23	2004-07-08	Janssen Pharmaceutica N.V.	Substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives and their use as neurokinin antagonists
JO2696B1 (en)	2002-12-23	2013-03-03	شركة جانسين فارماسوتيكا ان. في	Derivatives of 1-piperdine-4-yl-4-biprolidine-3-yl-piperazine substituted and used as quinine antagonists
JO2676B1 (en)	2004-04-06	2012-06-17	جانسين فارماسوتيكا ان. في	Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
JO2525B1 (en) *	2004-04-08	2010-03-17	شركة جانسين فارماسوتيكا ان. في	Derived 4-alkyl-and-4-canoelperidine derivatives and their use as anti-neroquin
KR101355064B1 (ko)	2005-03-03	2014-01-24	얀센 파마슈티카 엔.브이.	치환된 옥사-디아자-스피로-[5.5]-운데카논 유도체 및뉴로키닌 길항제로서의 이의 용도
ATE478075T1 (de)	2005-03-08	2010-09-15	Janssen Pharmaceutica Nv	Diazaspiro-ä4,4ü-nonanderivate als neurokinin- (nk1)-antagonisten
WO2009009829A1 (en) *	2007-07-19	2009-01-22	Adelaide Research & Innovation Pty Ltd	Method for reducing intracranial pressure
UA105182C2 (ru)	2008-07-03	2014-04-25	Ньюрексон, Інк.	Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
WO2013004766A1 (en)	2011-07-04	2013-01-10	Ferrari Giulio	Nk-1 receptor antagonists for treating corneal neovascularisation
CN111918647A (zh)	2018-02-26	2020-11-10	圣拉斐尔医院有限公司	用于治疗眼痛的nk-1拮抗剂
WO2021180885A1 (en)	2020-03-11	2021-09-16	Ospedale San Raffaele S.R.L.	Treatment of stem cell deficiency

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4329353A (en)	1980-10-22	1982-05-11	Janssen Pharmaceutica, N.V.	1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
ATE124045T1 (de) *	1990-10-10	1995-07-15	Schering Corp	Substituierte imidazobenzazepine und imidazopyridoazepine.
IL101851A (en) *	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
KR100346802B1 (ko) *	1993-07-13	2002-11-29	얀센 파마슈티카 엔.브이.	항앨러지성이미다조아제핀
TW397831B (en)	1994-07-15	2000-07-11	Meiji Seika Kaisha	The anti-platelet-agglutination hexahydrogenated pyridine and its derivatives
NZ321575A (en)	1995-10-30	1999-05-28	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives

1996
- 1996-12-13 TW TW085115390A patent/TW382017B/zh not_active IP Right Cessation
- 1996-12-20 SI SI9630419T patent/SI0843679T1/xx unknown
- 1996-12-20 BR BR9612307A patent/BR9612307A/pt not_active IP Right Cessation
- 1996-12-20 EP EP96944693A patent/EP0843679B1/en not_active Expired - Lifetime
- 1996-12-20 CN CN96199396A patent/CN1066733C/zh not_active Expired - Fee Related
- 1996-12-20 AU AU13086/97A patent/AU716071B2/en not_active Ceased
- 1996-12-20 AT AT96944693T patent/ATE208392T1/de active
- 1996-12-20 PL PL96327136A patent/PL183767B1/pl unknown
- 1996-12-20 CZ CZ19981865A patent/CZ295861B6/cs not_active IP Right Cessation
- 1996-12-20 JP JP52403397A patent/JP4097043B2/ja not_active Expired - Fee Related
- 1996-12-20 CA CA002238817A patent/CA2238817C/en not_active Expired - Fee Related
- 1996-12-20 SK SK830-98A patent/SK283540B6/sk unknown
- 1996-12-20 WO PCT/EP1996/005885 patent/WO1997024356A1/en not_active Ceased
- 1996-12-20 IL IL12464296A patent/IL124642A/en not_active IP Right Cessation
- 1996-12-20 ES ES96944693T patent/ES2167619T3/es not_active Expired - Lifetime
- 1996-12-20 DE DE69616802T patent/DE69616802T2/de not_active Expired - Lifetime
- 1996-12-20 DK DK96944693T patent/DK0843679T3/da active
- 1996-12-20 NZ NZ325845A patent/NZ325845A/xx not_active IP Right Cessation
- 1996-12-20 EA EA199800603A patent/EA001374B1/ru not_active IP Right Cessation
- 1996-12-20 TR TR1998/01210T patent/TR199801210T2/xx unknown
- 1996-12-20 IL IL12464196A patent/IL124641A/en not_active IP Right Cessation
- 1996-12-20 PT PT96944693T patent/PT843679E/pt unknown
- 1996-12-20 HU HU9903948 patent/HU229766B1/hu not_active IP Right Cessation
- 1996-12-20 KR KR10-1998-0704830A patent/KR100485147B1/ko not_active Expired - Fee Related
- 1996-12-23 ZA ZA9610889A patent/ZA9610889B/xx unknown
- 1996-12-26 AR ARP960105895A patent/AR005278A1/es active IP Right Grant
- 1996-12-27 MY MYPI96005516A patent/MY117680A/en unknown
1998
- 1998-05-27 NO NO19982405A patent/NO310916B1/no not_active IP Right Cessation
- 1998-06-22 US US09/102,136 patent/US6251894B1/en not_active Expired - Lifetime
2002
- 2002-04-25 CY CY0200023A patent/CY2271B1/xx unknown
2005
- 2005-12-16 AR ARP050105316A patent/AR051817A2/es active IP Right Grant

Also Published As

Publication number	Publication date
IL124642A0 (en)	1998-12-06
US6251894B1 (en)	2001-06-26
DE69616802D1 (de)	2001-12-13
DE69616802T2 (de)	2002-07-04
CZ186598A3 (cs)	1998-11-11
AR005278A1 (es)	1999-04-28
CA2238817C (en)	2006-10-17
PL183767B1 (pl)	2002-07-31
ATE208392T1 (de)	2001-11-15
CA2238817A1 (en)	1997-07-10
WO1997024356A1 (en)	1997-07-10
ZA9610889B (en)	1998-06-23
JP2000506503A (ja)	2000-05-30
IL124641A (en)	2001-11-25
NO982405L (no)	1998-08-19
CN1206417A (zh)	1999-01-27
DK0843679T3 (da)	2002-02-25
AR051817A2 (es)	2007-02-14
HUP9903948A3 (hu)	2000-04-28
CZ295861B6 (cs)	2005-11-16
SI0843679T1 (en)	2002-06-30
SK83098A3 (en)	1999-01-11
SK283540B6 (sk)	2003-09-11
PT843679E (pt)	2002-04-29
JP4097043B2 (ja)	2008-06-04
HUP9903948A2 (hu)	2000-03-28
CN1066733C (zh)	2001-06-06
EA199800603A1 (ru)	1998-12-24
NO982405D0 (no)	1998-05-27
EP0843679B1 (en)	2001-11-07
KR100485147B1 (ko)	2005-09-13
KR19990076715A (ko)	1999-10-15
IL124642A (en)	2002-08-14
EA001374B1 (ru)	2001-02-26
ES2167619T3 (es)	2002-05-16
HU229766B1 (hu)	2014-06-30
MY117680A (en)	2004-07-31
HK1011206A1 (en)	1999-07-09
NZ325845A (en)	1999-06-29
TR199801210T2 (xx)	1999-10-21
AU716071B2 (en)	2000-02-17
IL124641A0 (en)	1998-12-06
NO310916B1 (no)	2001-09-17
PL327136A1 (en)	1998-11-23
AU1308697A (en)	1997-07-28
EP0843679A1 (en)	1998-05-27
TW382017B (en)	2000-02-11
CY2271B1 (en)	2003-07-04

Legal Events

Date	Code	Title	Description
2003-09-23	FB36	Technical and formal requirements: requirement - article 36 of industrial property law
2004-03-09	HJEG	Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
2004-08-03	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2005-03-15	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
2016-10-25	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 20A ANUIDADE.
2017-02-21	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Publication	Publication Date	Title
BR9612307A (pt)	1999-07-13	Derivados de 1-(1,2-piperidinil di-substituído)-4-(mizadol fundido)-piperidina
BR9611184A (pt)	1999-03-30	Derivados de 1-(1,2-Piperidinil dissubstituído)-4-piperazina substituída
FI955184A7 (fi)	1996-05-01	Bentsyylipiperidiinijohdannaiset
DE69226449D1 (de)	1998-09-03	2-(2,6-difluorphenyl)-4-(2-ethoxy-4-tert-butylphenyl)-2-axazoline
DE69631390D1 (de)	2004-02-26	Substituierte Benzylaminpiperidin-Verbindungen
CZ186498A3 (cs)	1998-12-16	1-(1,2-Disubstituovaný piperidinyl)-4-substituované deriváty piperidinu
PT876359E (pt)	2003-12-31	D-tartarato de (-)- cis-6(s)-fenil-5(r)-¬4-(2-pirrolidin-1-iletoxi)fenil\|-5,6,7,8-tetra-hidronaftalen-2-ol
FI964898A7 (fi)	1996-12-05	4-aryyli-1-(indaanimetyyli-, dihydrobentsofuraanimetyyli- tai dihydrobentsotiofeenimetyyli) piperidiinejä, -tetra-hydropyridiinejä tai -piperatsiineja
DE122007000005I2 (de)	2008-04-24	Apolipoprotein-b syntheseinhibitoren
NO980290D0 (no)	1998-01-22	2(4-substituert)benzylamino-2-metylpropanamidderivater
BR9606815A (pt)	1997-12-30	Derivados de piperidina 4-(1H-indolil-1-il)-1-substituídos antipsicóticos
SV1996000004A (es)	1997-02-19	2-(2-n-alcoxifenil)-purin-6-onas 9 sustituidas
NO944487D0 (no)	1994-11-23	8-klor-11[1-[(5-metyl-3-pyridyl)metylÅ-4-piperidylidenÅ-6,11-dihydro-5H-benzo[5,6Åsyklohepta-[1,2-bÅpyridinfumarat
FI972239A0 (fi)	1997-05-27	(Tiofen-2-yyli) piperidiini- tai tetrahydropyridiinikarboksamideja
KR970006301A (ko)	1997-02-19	-피페리딘 또는 테트라하이드로피리딘 아자비사이클로카복스아미드
ITMI941593A0 (it)	1994-07-26	Tetraidropiridine 3,3-disostituite
FI960615A7 (fi)	1996-08-10	1-(2-(substituoitu-vinyyli))-5H-2,3-bentsodiatsepiinijohdannaiset
KR970027569U (ko)	1997-07-24	밀링머신 세팅 바
BR9504235A (pt)	1997-09-09	Refratário moldável/fusível
KR970011205U (ko)	1997-03-29	와이어 본딩용 히터 블록
KR970011867U (ko)	1997-04-25	넥타이홀더
KR970019644U (ko)	1997-05-26	퓨우즈용 홀더
KR970046483U (ko)	1997-07-31	휴즈 접속용 홀더