BR9911217A - Métodos para ampliação dos nìveis de acetilcolina - Google Patents
Métodos para ampliação dos nìveis de acetilcolinaInfo
- Publication number
- BR9911217A BR9911217A BR9911217-5A BR9911217A BR9911217A BR 9911217 A BR9911217 A BR 9911217A BR 9911217 A BR9911217 A BR 9911217A BR 9911217 A BR9911217 A BR 9911217A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- acetylcholine levels
- increasing acetylcholine
- levels
- increasing
- Prior art date
Links
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004373 acetylcholine Drugs 0.000 title abstract 3
- 229940124596 AChE inhibitor Drugs 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Patente de Invenção: <B>"MéTODOS PARA AMPLIAçãO DOS NìVEIS DE ACETILCOLINA"<D>. A presente invenção refere-se a um método para ampliação dos níveis de acetilcolina compreendendo a administração a um mamífero necessitado da mesma de uma quantidade eficiente de um composto de fórmula I e, opcionalmente, de um inibidor de AChE.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8948898P | 1998-06-16 | 1998-06-16 | |
| PCT/US1999/012603 WO1999065309A1 (en) | 1998-06-16 | 1999-06-04 | Methods for increasing levels of acetylcholine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9911217A true BR9911217A (pt) | 2001-03-06 |
Family
ID=22217922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9911217-5A BR9911217A (pt) | 1998-06-16 | 1999-06-04 | Métodos para ampliação dos nìveis de acetilcolina |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0966964A1 (pt) |
| JP (1) | JP2002518299A (pt) |
| KR (1) | KR20010052892A (pt) |
| CN (1) | CN1305343A (pt) |
| AU (1) | AU748659B2 (pt) |
| BR (1) | BR9911217A (pt) |
| CA (1) | CA2333453A1 (pt) |
| HR (1) | HRP20000861A2 (pt) |
| HU (1) | HUP0103834A2 (pt) |
| IL (1) | IL138914A0 (pt) |
| NO (1) | NO20006088D0 (pt) |
| PL (1) | PL346242A1 (pt) |
| SK (1) | SK18812000A3 (pt) |
| TR (1) | TR200003714T2 (pt) |
| TW (1) | TW486367B (pt) |
| WO (1) | WO1999065309A1 (pt) |
| ZA (1) | ZA200005885B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6288108B1 (en) | 1998-06-16 | 2001-09-11 | Eli Lilly And Company | Methods for increasing levels of acetylcholine |
| KR20010052891A (ko) | 1998-06-16 | 2001-06-25 | 피터 지. 스트링거 | 아세틸콜린 수치를 상승시키는 방법 |
| KR101226702B1 (ko) * | 2010-10-08 | 2013-01-25 | 충북대학교 산학협력단 | 인간 콜린 아세틸트랜스퍼라아제를 발현하는 인간 신경줄기세포 및 이의 용도 |
| KR102117741B1 (ko) * | 2017-12-31 | 2020-06-01 | 롯데첨단소재(주) | 도금용 열가소성 수지 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995017095A1 (en) * | 1993-12-21 | 1995-06-29 | Eli Lilly And Company | Methods for the treatment or prevention of conditions associated with amyloidogenic reptides |
| US5552415A (en) * | 1993-12-21 | 1996-09-03 | Eli Lilly And Company | Method of inhibiting Alzheimer's Disease |
| US5510357A (en) * | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
| UA44710C2 (uk) * | 1995-02-28 | 2002-03-15 | Елі Ліллі Енд Компані | Похідні бензотіофену, спосіб їх одержання (варіанти), проміжні сполуки, фармацевтична композиція |
| SI9720038B (sl) * | 1996-06-07 | 2010-06-30 | Eisai Co Ltd | Polimorfi donepezil hidroklorida in postopek izdelave |
| ZA982877B (en) * | 1997-04-09 | 1999-10-04 | Lilly Co Eli | Treatment of central nervous system disorders with selective estrogen receptor modulators. |
-
1999
- 1999-06-04 WO PCT/US1999/012603 patent/WO1999065309A1/en not_active Ceased
- 1999-06-04 IL IL13891499A patent/IL138914A0/xx unknown
- 1999-06-04 SK SK1881-2000A patent/SK18812000A3/sk unknown
- 1999-06-04 AU AU48191/99A patent/AU748659B2/en not_active Ceased
- 1999-06-04 JP JP2000554200A patent/JP2002518299A/ja not_active Withdrawn
- 1999-06-04 PL PL99346242A patent/PL346242A1/xx unknown
- 1999-06-04 HU HU0103834A patent/HUP0103834A2/hu unknown
- 1999-06-04 CN CN99807286A patent/CN1305343A/zh active Pending
- 1999-06-04 CA CA002333453A patent/CA2333453A1/en not_active Abandoned
- 1999-06-04 TR TR2000/03714T patent/TR200003714T2/xx unknown
- 1999-06-04 HR HR20000861A patent/HRP20000861A2/hr not_active Application Discontinuation
- 1999-06-04 BR BR9911217-5A patent/BR9911217A/pt not_active IP Right Cessation
- 1999-06-04 KR KR1020007014237A patent/KR20010052892A/ko not_active Withdrawn
- 1999-06-10 TW TW088109701A patent/TW486367B/zh not_active IP Right Cessation
- 1999-06-11 EP EP99304581A patent/EP0966964A1/en not_active Withdrawn
-
2000
- 2000-10-20 ZA ZA200005885A patent/ZA200005885B/en unknown
- 2000-11-30 NO NO20006088A patent/NO20006088D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL346242A1 (en) | 2002-01-28 |
| AU748659B2 (en) | 2002-06-06 |
| EP0966964A1 (en) | 1999-12-29 |
| SK18812000A3 (sk) | 2002-01-07 |
| NO20006088L (no) | 2000-11-30 |
| KR20010052892A (ko) | 2001-06-25 |
| JP2002518299A (ja) | 2002-06-25 |
| AU4819199A (en) | 2000-01-05 |
| WO1999065309A1 (en) | 1999-12-23 |
| NO20006088D0 (no) | 2000-11-30 |
| HRP20000861A2 (en) | 2001-10-31 |
| ZA200005885B (en) | 2001-10-22 |
| CN1305343A (zh) | 2001-07-25 |
| CA2333453A1 (en) | 1999-12-23 |
| TR200003714T2 (tr) | 2001-07-23 |
| TW486367B (en) | 2002-05-11 |
| HUP0103834A2 (hu) | 2002-05-29 |
| IL138914A0 (en) | 2001-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5,6,7 E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |