BRPI0011152B8 - peptídeos inibidores da exocitose neuronal, mistura de peptídeos, composições cosméticas e farmacêuticas, utilização de um peptídeo, e, método para o tratamento cosmético em um ser humano das rugas faciais e/ou da assimetria facial - Google Patents
peptídeos inibidores da exocitose neuronal, mistura de peptídeos, composições cosméticas e farmacêuticas, utilização de um peptídeo, e, método para o tratamento cosmético em um ser humano das rugas faciais e/ou da assimetria facialInfo
- Publication number
- BRPI0011152B8 BRPI0011152B8 BRPI0011152A BRPI0011152A BRPI0011152B8 BR PI0011152 B8 BRPI0011152 B8 BR PI0011152B8 BR PI0011152 A BRPI0011152 A BR PI0011152A BR PI0011152 A BRPI0011152 A BR PI0011152A BR PI0011152 B8 BRPI0011152 B8 BR PI0011152B8
- Authority
- BR
- Brazil
- Prior art keywords
- cosmetic
- peptides
- facial
- peptide
- pharmaceutical compositions
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 239000002537 cosmetic Substances 0.000 title abstract 4
- 230000028023 exocytosis Effects 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 230000001537 neural effect Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 206010068737 Facial asymmetry Diseases 0.000 title abstract 2
- 230000001815 facial effect Effects 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000037303 wrinkles Effects 0.000 title abstract 2
- 230000001575 pathological effect Effects 0.000 abstract 2
- 102000004183 Synaptosomal-Associated Protein 25 Human genes 0.000 abstract 1
- 108010057722 Synaptosomal-Associated Protein 25 Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Immunology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"péptidos inibidores da exocitosis neurónica, composições cosméticas e farmacêuticas que os contêm". o péptido tem uma sequência de 3 a 30 amino-ácidos contíguos procedentes do extremo amino da proteína snap-25 e é útil como inibidor da exocitosis neurónica. as composições cosméticas e farmacêuticas compreendem o mencionado péptido, opcionalmente junto com um ou mais péptidos procedentes do extremo carboxilo da snap-25. as composições são adequadas para o tratamento das rugas faciais, da assimetria facial e de transtornos e alterações patológicas mediadas por uma exócitosis neurónica patológica.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009900844A ES2160485B1 (es) | 1999-04-23 | 1999-04-23 | Peptidos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen. |
| ESP9900844 | 1999-04-23 | ||
| PCT/ES2000/000058 WO2000064932A1 (es) | 1999-04-23 | 2000-02-18 | Peptitos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0011152B1 BRPI0011152B1 (pt) | 2018-03-13 |
| BRPI0011152B8 true BRPI0011152B8 (pt) | 2022-05-10 |
Family
ID=8308129
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0011152A BRPI0011152B8 (pt) | 1999-04-23 | 2000-02-18 | peptídeos inibidores da exocitose neuronal, mistura de peptídeos, composições cosméticas e farmacêuticas, utilização de um peptídeo, e, método para o tratamento cosmético em um ser humano das rugas faciais e/ou da assimetria facial |
| BR0011152-0A BR0011152A (pt) | 1999-04-23 | 2000-02-18 | Péptidos inibidores da exocitosis neurónica, composições cosméticas e farmacêuticas que os contêm |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0011152-0A BR0011152A (pt) | 1999-04-23 | 2000-02-18 | Péptidos inibidores da exocitosis neurónica, composições cosméticas e farmacêuticas que os contêm |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7015192B1 (pt) |
| EP (1) | EP1180524B2 (pt) |
| JP (2) | JP4363556B2 (pt) |
| AT (1) | ATE338062T1 (pt) |
| AU (1) | AU2672900A (pt) |
| BR (2) | BRPI0011152B8 (pt) |
| CA (1) | CA2370289C (pt) |
| DE (1) | DE60030429T3 (pt) |
| DK (1) | DK1180524T4 (pt) |
| ES (1) | ES2160485B1 (pt) |
| PT (1) | PT1180524E (pt) |
| WO (1) | WO2000064932A1 (pt) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2160485B1 (es) * | 1999-04-23 | 2002-05-16 | Lipotec Sa | Peptidos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen. |
| EP1301213B1 (en) | 2000-07-21 | 2017-01-18 | ReVance Therapeutics, Inc. | Multi-component biological transport systems |
| US7332567B2 (en) * | 2001-08-28 | 2008-02-19 | Allergan, Inc. | Fret protease assays for clostridial toxins |
| FR2846885B1 (fr) * | 2002-11-13 | 2004-12-24 | Oreal | Utilisation d'une association de composants a effet synergique inhibiteur de canaux calciques pour prevenir ou traiter les ridules |
| US7071167B2 (en) | 2002-11-13 | 2006-07-04 | L'oreal | Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat wrinkles and fine lines |
| JP2004323400A (ja) * | 2003-04-23 | 2004-11-18 | Mikimoto Pharmaceut Co Ltd | 皮膚外用剤 |
| CA2558676C (en) | 2004-03-03 | 2019-04-16 | Essentia Biosystems, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| CN1946431B (zh) | 2004-03-03 | 2011-12-07 | 雷文斯治疗公司 | 用于肉毒毒素的局部施用和透皮递送的组合物和方法 |
| US20060073208A1 (en) | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| CA2584643C (en) * | 2004-11-02 | 2013-01-29 | Pentapharm Ag | New, topically applicable actives against mimic and age-related wrinkles |
| SG160357A1 (en) | 2005-03-03 | 2010-04-29 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| CN101160318A (zh) | 2005-03-03 | 2008-04-09 | 雷文斯治疗公司 | 用于局部施用和经皮肤递送寡肽的组合物和方法 |
| ES2259928B1 (es) * | 2005-04-08 | 2007-11-01 | Lipotec, S.A. | Composicion cosmetica o dermofarmaceutica que comprende peptidos derivados de encefalinas para reducir y/o eliminar arrugas faciales. |
| NZ568216A (en) | 2005-11-17 | 2012-09-28 | Revance Therapeutics Inc | Compositions and methods of topical application and transdermal delivery of botulinum toxins with reduced non-toxin proteins |
| WO2007071448A2 (en) * | 2005-12-23 | 2007-06-28 | Partnership & Corp. Technology Transfer | Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation |
| ES2322882B1 (es) * | 2006-10-25 | 2010-04-22 | Lipotec Sa | Peptidos inhibidores de la exocitosis neuronal. |
| EP1992332A1 (en) * | 2007-05-08 | 2008-11-19 | Tupperware Products S.A. | Cosmetic anti ageing skin care compositions |
| ES2356883B1 (es) * | 2008-07-24 | 2012-02-22 | Bcn Peptides, S.A. | Composición para el tratamiento del dolor y/o la inflamación. |
| JP5782439B2 (ja) * | 2009-07-24 | 2015-09-24 | リポテック, エセ.ア.Lipotec, S.A. | 筋肉収縮を抑制する化合物 |
| US20130078295A1 (en) * | 2010-06-09 | 2013-03-28 | Lipotec S.A. | Skin antiaging treatment |
| US20110305735A1 (en) * | 2010-06-09 | 2011-12-15 | Lipotec, S.A. | Skin antiaging treatment |
| ES2385683B1 (es) * | 2010-10-18 | 2013-10-07 | Bcn Peptides, S.A. | Composiciones para el tratamiento del dolor y/o la inflamación. |
| WO2013070808A1 (en) * | 2011-11-07 | 2013-05-16 | Feng Tian | Peptide-based compounds as inhibitors of neurotransmitter secretion |
| ES2424294B1 (es) | 2012-03-22 | 2014-07-21 | Lipotec, S.A. | Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas |
| US10149812B2 (en) | 2012-04-13 | 2018-12-11 | Activen | Cosmetic composition comprising a muconopeptide |
| EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
| WO2013153236A2 (en) | 2012-04-13 | 2013-10-17 | Activen | Cosmetic composition comprising a muconopeptide |
| EP2836193B1 (en) | 2012-04-13 | 2018-01-31 | Lubrizol Advanced Materials, Inc. | Compounds which inhibit neuronal exocytosis (ii) |
| EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
| EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
| WO2015063613A2 (en) | 2013-11-01 | 2015-05-07 | Spherium Biomed S.L. | Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents |
| MX394677B (es) | 2014-10-31 | 2025-03-24 | Lubrizol Advanced Mat Inc | Pelicula de poliuretano termoplastico para la liberacion de agentes activos a superficies de piel. |
| CN104478991B (zh) * | 2014-12-10 | 2018-06-19 | 深圳市维琪医药研发有限公司 | 一种新型多肽化合物及其制备方法和其医药应用 |
| CN104829691B (zh) * | 2015-05-19 | 2018-11-02 | 山西锦波生物医药股份有限公司 | 除皱短肽及其制备方法 |
| US20180311358A1 (en) | 2015-11-05 | 2018-11-01 | Lubrizol Advanced Materials, Inc. | Thermoformable dual network hydrogel compositions |
| ES2937382T3 (es) | 2018-02-27 | 2023-03-28 | Lipotrue S L | Péptidos y composiciones para uso en cosmética y medicina |
| WO2019238683A1 (en) | 2018-06-13 | 2019-12-19 | Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.P.A. | Peptides having inhibitory activity on neuronal exocytosis |
| EP3833674A1 (en) | 2018-08-10 | 2021-06-16 | Lubrizol Advanced Materials, Inc. | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes |
| JP2022514114A (ja) | 2018-10-16 | 2022-02-09 | ジーエルオー ファーマ,インク. | ニコチン性アセチルコリン受容体ペプチドアンタゴニストであるコノトキシン組成物、およびこれに関連する方法 |
| MX2020014330A (es) * | 2018-12-26 | 2021-03-09 | Caregen Co Ltd | Composicion para relajacion muscular. |
| EP4144337B1 (en) | 2021-09-02 | 2024-08-07 | Guangzhou Jiyan Cosmetics Technology Co. Ltd. | Vitis vinifera cosmetic composition |
| CN113826764B (zh) * | 2021-09-24 | 2024-07-12 | 江苏三仪生物工程有限公司 | 一种大豆小肽螯合铁的制备方法 |
| EP4230638A1 (en) | 2022-02-16 | 2023-08-23 | Lipotrue, S.L. | Peptides and compositions for use in cosmetics |
| US20250161409A1 (en) | 2022-02-23 | 2025-05-22 | Prospera Biotech, S.L. | Compositions for treating hyperhidrosis |
| CN117203217B (zh) | 2022-03-28 | 2024-11-29 | 深圳市维琪科技股份有限公司 | 一种多肽及其组合物和用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6169074B1 (en) * | 1996-03-18 | 2001-01-02 | The Regents Of The University Of California | Peptide inhibitors of neurotransmitter secretion by neuronal cells |
| ES2160485B1 (es) * | 1999-04-23 | 2002-05-16 | Lipotec Sa | Peptidos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen. |
-
1999
- 1999-04-23 ES ES009900844A patent/ES2160485B1/es not_active Expired - Fee Related
-
2000
- 2000-02-18 AT AT00905076T patent/ATE338062T1/de active
- 2000-02-18 BR BRPI0011152A patent/BRPI0011152B8/pt unknown
- 2000-02-18 DE DE60030429T patent/DE60030429T3/de not_active Expired - Lifetime
- 2000-02-18 PT PT00905076T patent/PT1180524E/pt unknown
- 2000-02-18 JP JP2000614281A patent/JP4363556B2/ja not_active Expired - Lifetime
- 2000-02-18 US US10/030,485 patent/US7015192B1/en not_active Expired - Lifetime
- 2000-02-18 CA CA2370289A patent/CA2370289C/en not_active Expired - Lifetime
- 2000-02-18 DK DK00905076.6T patent/DK1180524T4/da active
- 2000-02-18 AU AU26729/00A patent/AU2672900A/en not_active Abandoned
- 2000-02-18 WO PCT/ES2000/000058 patent/WO2000064932A1/es not_active Ceased
- 2000-02-18 EP EP00905076A patent/EP1180524B2/en not_active Expired - Lifetime
- 2000-02-18 BR BR0011152-0A patent/BR0011152A/pt not_active IP Right Cessation
-
2006
- 2006-01-09 US US11/327,952 patent/US7473679B2/en not_active Expired - Fee Related
-
2009
- 2009-06-17 JP JP2009144480A patent/JP4892037B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2370289C (en) | 2011-04-19 |
| DE60030429D1 (de) | 2006-10-12 |
| EP1180524A1 (en) | 2002-02-20 |
| BR0011152A (pt) | 2002-02-19 |
| ES2160485B1 (es) | 2002-05-16 |
| EP1180524B1 (en) | 2006-08-30 |
| DE60030429T3 (de) | 2012-01-12 |
| WO2000064932A1 (es) | 2000-11-02 |
| BRPI0011152B1 (pt) | 2018-03-13 |
| DK1180524T3 (da) | 2006-12-11 |
| JP2002542777A (ja) | 2002-12-17 |
| EP1180524B2 (en) | 2010-07-07 |
| JP4363556B2 (ja) | 2009-11-11 |
| US20060276392A1 (en) | 2006-12-07 |
| US7473679B2 (en) | 2009-01-06 |
| JP4892037B2 (ja) | 2012-03-07 |
| DK1180524T4 (da) | 2010-10-25 |
| JP2009221223A (ja) | 2009-10-01 |
| ATE338062T1 (de) | 2006-09-15 |
| CA2370289A1 (en) | 2000-11-02 |
| US7015192B1 (en) | 2006-03-21 |
| DE60030429T2 (de) | 2007-10-31 |
| AU2672900A (en) | 2000-11-10 |
| ES2160485A1 (es) | 2001-11-01 |
| PT1180524E (pt) | 2007-01-31 |
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