CA2015994A1 - Sequence d'adn-c de lactoferrine humaine - Google Patents

Sequence d'adn-c de lactoferrine humaine

Info

Publication number
CA2015994A1
CA2015994A1 CA2015994A CA2015994A CA2015994A1 CA 2015994 A1 CA2015994 A1 CA 2015994A1 CA 2015994 A CA2015994 A CA 2015994A CA 2015994 A CA2015994 A CA 2015994A CA 2015994 A1 CA2015994 A1 CA 2015994A1
Authority
CA
Canada
Prior art keywords
cdna sequence
human lactoferrin
lactoferrin cdna
hlf
cdna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2015994A
Other languages
English (en)
Other versions
CA2015994C (fr
Inventor
Denis R. Headon
Orla M. Conneely
Bert W. O'malley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Granada Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23367308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2015994(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Granada Biosciences Inc filed Critical Granada Biosciences Inc
Publication of CA2015994A1 publication Critical patent/CA2015994A1/fr
Application granted granted Critical
Publication of CA2015994C publication Critical patent/CA2015994C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA002015994A 1989-05-05 1990-05-03 Sequence d'adn-c de lactoferrine humaine Expired - Lifetime CA2015994C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34827089A 1989-05-05 1989-05-05
US348,270 1989-05-05

Publications (2)

Publication Number Publication Date
CA2015994A1 true CA2015994A1 (fr) 1990-11-05
CA2015994C CA2015994C (fr) 2000-02-15

Family

ID=23367308

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002015994A Expired - Lifetime CA2015994C (fr) 1989-05-05 1990-05-03 Sequence d'adn-c de lactoferrine humaine

Country Status (13)

Country Link
US (3) US6228614B1 (fr)
EP (1) EP0471011B2 (fr)
JP (1) JP2701976B2 (fr)
AT (1) ATE112801T1 (fr)
AU (1) AU5661890A (fr)
CA (1) CA2015994C (fr)
DE (1) DE69013342T3 (fr)
DK (1) DK0471011T4 (fr)
ES (1) ES2061038T5 (fr)
IE (1) IE66820B1 (fr)
IL (1) IL94183A (fr)
NZ (1) NZ233450A (fr)
WO (1) WO1990013642A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571697A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Texas Medical Center Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
IL94183A (en) 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US6066469A (en) 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
DK0510912T3 (da) * 1991-04-24 1998-02-09 Morinaga Milk Industry Co Ltd Antimikrobielt peptid og antimikrobielt middel
AU2029192A (en) * 1991-05-31 1993-01-08 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Human lactoferrin
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
JP3529423B2 (ja) * 1994-04-01 2004-05-24 森永乳業株式会社 抗菌性ペプチドの製造方法
WO1995030339A1 (fr) * 1994-05-05 1995-11-16 Ferrodynamics, Inc. Clonage, expression et utilisations de la lactoferrine humaine
FR2735983B1 (fr) 1995-06-29 1997-12-05 Centre Nat Rech Scient Peptide permettant de modifier l'activite du systeme immunitaire humain ou animal
DE19540233B4 (de) * 1995-10-19 2005-08-25 Schering Ag Sulfamat-Derivate von 1,3,5(10)-Estratrien-Derivaten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
ES2212357T3 (es) 1997-09-16 2004-07-16 Wolf-Georg Forssmann Peptidos bifidogenos y su uso.
US6399570B1 (en) * 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
EP1245236A4 (fr) * 1999-12-28 2004-09-22 Sumitomo Pharma Produits therapeutiques et prophylactiques pour l'hepatique chronique
WO2003057712A2 (fr) * 2001-12-28 2003-07-17 Campina B.V. Lactoferrine humanisee et utilisations de celle-ci
CN100467059C (zh) 2002-05-10 2009-03-11 阿根尼克斯有限公司 乳铁蛋白在治疗恶性肿瘤疾病中的用途
US7238661B2 (en) * 2002-05-24 2007-07-03 Agennix, Inc. Oral lactoferrin in the treatment of respiratory disorders
DE60335997D1 (de) * 2002-09-16 2011-03-24 Agennix Inc Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus
CA2508912A1 (fr) * 2002-12-06 2004-06-24 Agennix Incorporated Lactoferrine orale pour le traitement des sepsies
AU2003296447A1 (en) 2002-12-10 2004-06-30 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
AU2003293500A1 (en) * 2002-12-12 2004-07-09 Agennix Incorporated Lactoferrin in the reduction of pain
WO2004103285A2 (fr) * 2003-05-14 2004-12-02 Agennix Incorporated Lactoferrine pour traitement du diabete sucre
US8105615B2 (en) * 2003-06-06 2012-01-31 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
WO2005018542A2 (fr) * 2003-07-10 2005-03-03 Agennix Incorporated Utilisation de lactoferrine dans une prophylaxie dirigee contre une infection et/ou contre une inflammation, chez des patients immunosupprimes
WO2006047744A2 (fr) * 2004-10-26 2006-05-04 Agennix Incorporated Compositions de peptides en rapport avec la lactoferrine et utilisations
WO2006074450A2 (fr) * 2005-01-07 2006-07-13 President And Fellows Of Harvard College Methodes et compositions permettant de detecter et de moduler les maladies et les troubles parodontaux
US20090149166A1 (en) * 2006-04-24 2009-06-11 Hakem Mohamedali Habib Method, system and apparatus for conveying an event reminder
NZ555163A (en) 2007-05-14 2010-05-28 Fonterra Co Operative Group Methods of immune or hematological enhancement, inhibiting tumour formation or growth, and treating or preventing cancer, cancer symptoms, or the symptoms of cancer treatments
EP2560677A4 (fr) * 2010-04-23 2013-09-11 Probiotec Ltd Traitement du rhume
RU2554742C1 (ru) * 2013-12-26 2015-06-27 Российская Федерация, от имени которой выступает Министерство образования и науки РФ Технология опытного выделения лактоферрина человека
SMT201800031T1 (it) * 2015-11-20 2018-03-08 Geroa Diagnostics S L Lattoferrina per uso nella diagnosi o nella prognosi della malattia di alzheimer
TWI614022B (zh) * 2016-02-23 2018-02-11 肌活麗學創研所股份有限公司 降低黑色素含量的胜肽、方法及組合物
EP4200424A1 (fr) * 2020-08-18 2023-06-28 Novozymes A/S Dispersines exprimées avec des peptides signal d'amylase

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US142037A (en) * 1873-08-19 Improvement in match-planes
US105006A (en) * 1870-07-05 Improvement in cotton-seed planters
US190303A (en) * 1877-05-01 Improvement in ticket-punches
US9895A (en) * 1853-08-02 Apparatus to regrulate the supply of water
US9896A (en) * 1853-08-02 Abdominal suppobtek
US82504A (en) * 1868-09-29 Improvement in mitre-machines
US75277A (en) * 1868-03-10 Improvement in deiees
US733621A (en) * 1902-07-07 1903-07-14 W G Browne Mfg Company Egg-beater.
US728521A (en) * 1902-08-05 1903-05-19 Edward Turney Clutch-operating mechanism.
US732429A (en) * 1902-10-06 1903-06-30 Charles E Napp Holder for directory-leaves, &c.
US728275A (en) * 1902-12-08 1903-05-19 Jesse Morgenthau Coin-operated weighing-machine.
US862213A (en) * 1905-10-09 1907-08-06 David J Strassel Ribbon-slide.
US844865A (en) * 1906-08-24 1907-02-19 William J M Hames Polisher and cleaner.
IN150740B (fr) 1978-11-24 1982-12-04 Hoffmann La Roche
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4394443A (en) 1980-12-18 1983-07-19 Yale University Method for cloning genes
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US4652639A (en) 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
JPS6016669A (ja) 1983-07-08 1985-01-28 石川島播磨重工業株式会社 浮基礎式貯槽の底板の建設方法
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
US4740461A (en) 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
US4710465A (en) 1984-04-19 1987-12-01 Yale University Junction-fragment DNA probes and probe clusters
LU85479A1 (fr) 1984-07-25 1986-02-12 Oleofina Sa Compositions antibacteriennes de nourriture pour animaux et procede pour les preparer
JPS61145200A (ja) 1984-12-19 1986-07-02 Snow Brand Milk Prod Co Ltd ウシラクトフェリンの分離精製法
US4886747A (en) 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
AU5912586A (en) 1985-06-20 1986-12-24 Salk Institute Biotechnology/Industrial Associates, Inc., The Alpha-factor leader peptide-facilitated secretion from transformed s cerevisiae
US4959318A (en) 1985-06-27 1990-09-25 Zymogenetics, Inc. Expression of protein C
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
FR2600250B1 (fr) 1986-06-23 1989-11-24 Bio Serae Procede pour conditionner une composition antibacterienne et composition antibacterienne conditionnee
US4965190A (en) 1986-07-31 1990-10-23 Howard Hughes Medical Institute Methods for the identification of mutations in the human phenylalanine hydroxylase gene using DNA probes
US4977137B1 (en) * 1987-06-03 1994-06-28 Baylor College Medicine Lactoferrin as a dietary ingredient promoting the growth of the gastrointestinal tract
US5019508A (en) 1987-08-27 1991-05-28 Biotechnology Research Partners, Ltd. Synovial phospholipases
EP0383779B2 (fr) 1987-09-04 2000-05-31 Novo Nordisk A/S PROCEDE DE PRODUCTION DE PROTEINES DANS $i(ASPERGILLUS) ET PROMOTEURS DESTINES A EXPRIMER CE CHAMPIGNON
US5081227A (en) 1988-03-04 1992-01-14 La Jolla Cancer Research Foundation Germ cell alkaline phosphatase
US5571697A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Texas Medical Center Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
US6100054A (en) * 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
IL94183A (en) * 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US5766939A (en) * 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5155037A (en) 1989-08-04 1992-10-13 The Texas A&M University System Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
WO1991005045A1 (fr) 1989-09-28 1991-04-18 Granada Biosciences, Inc. SEQUENCE D'ADNc ET D'ACIDE AMINE DE LACTOFERINE PORCINE
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
CA2075206C (fr) 1989-12-01 2006-05-23 Herbert L. Heyneker Production de polypeptides recombinants par des especes bovines et methodes transgeniques
US5198419A (en) * 1989-12-08 1993-03-30 Immuno Japan Inc. Formulated medicines for enhancing the efficacy of beta-lactam antibiotics in prophylaxis and treatment against infectious disease due to pathogenic bacteria
US6066469A (en) * 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
WO1991013982A1 (fr) 1990-03-08 1991-09-19 Ferrodynamics, Inc. Lactoferrine humaine produite par technique genetique
US5166145A (en) 1990-09-10 1992-11-24 Alza Corporation Antiemetic therapy
NZ245713A (en) 1992-02-10 1994-12-22 Novopharm Ltd Production of the antibiotic lovastatin from genetically engineered aspergillus strains
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
JP3557011B2 (ja) * 1995-03-30 2004-08-25 株式会社東芝 半導体発光素子、及びその製造方法
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
US6399570B1 (en) * 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide

Also Published As

Publication number Publication date
US6635447B1 (en) 2003-10-21
DK0471011T3 (da) 1994-11-14
DE69013342T3 (de) 2005-02-17
IE901483L (en) 1990-11-05
ES2061038T5 (es) 2005-03-16
DE69013342T2 (de) 1995-03-23
CA2015994C (fr) 2000-02-15
ATE112801T1 (de) 1994-10-15
DE69013342D1 (de) 1994-11-17
EP0471011A1 (fr) 1992-02-19
IE66820B1 (en) 1996-02-07
NZ233450A (en) 1992-10-28
IL94183A0 (en) 1991-01-31
EP0471011B2 (fr) 2004-08-18
DK0471011T4 (da) 2004-09-13
JP2701976B2 (ja) 1998-01-21
EP0471011B1 (fr) 1994-10-12
ES2061038T3 (es) 1994-12-01
WO1990013642A1 (fr) 1990-11-15
US6228614B1 (en) 2001-05-08
IL94183A (en) 2003-09-17
US20050064546A1 (en) 2005-03-24
AU5661890A (en) 1990-11-29
JPH04505101A (ja) 1992-09-10

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