CA2079275A1 - Melanges de polymeres de glycolide et de lactide et de homopolymeres et copolymeres poly(p-dioxanone), et sutures resorbables fabriquees a partir de ces materiaux - Google Patents

Melanges de polymeres de glycolide et de lactide et de homopolymeres et copolymeres poly(p-dioxanone), et sutures resorbables fabriquees a partir de ces materiaux

Info

Publication number: CA2079275A1
Authority: CA; Canada
Prior art keywords: glycolide; lactide; dioxanone; copolymer; poly
Prior art date: 1991-09-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002079275A

Other languages

English (en)

Inventor

Donald S. Kaplan

Ross R. Muth

Matthew Hermes

John Kennedy

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

United States Surgical Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-30

Filing date

1992-09-28

Publication date

1993-03-31

1992-09-28 Application filed by Individual filed Critical Individual

1993-03-31 Publication of CA2079275A1 publication Critical patent/CA2079275A1/fr

Status Abandoned legal-status Critical Current

Links

RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 title claims abstract description 96
229920001577 copolymer Polymers 0.000 title claims abstract description 81
JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 title claims abstract description 63
229920001519 homopolymer Polymers 0.000 title claims abstract description 32
229920002463 poly(p-dioxanone) polymer Polymers 0.000 title claims abstract description 30
239000000203 mixture Substances 0.000 title claims description 85
-1 poly(p-dioxanone) Polymers 0.000 title claims description 55
229920000642 polymer Polymers 0.000 title claims description 45
VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims abstract description 36
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 12
BYEAHWXPCBROCE-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoropropan-2-ol Chemical compound FC(F)(F)C(O)C(F)(F)F BYEAHWXPCBROCE-UHFFFAOYSA-N 0.000 claims description 7
210000000988 bone and bone Anatomy 0.000 claims description 4
238000004519 manufacturing process Methods 0.000 claims description 4
229920002959 polymer blend Polymers 0.000 abstract description 8
125000004122 cyclic group Chemical group 0.000 abstract description 5
239000000178 monomer Substances 0.000 description 11
238000002347 injection Methods 0.000 description 8
239000007924 injection Substances 0.000 description 8
238000012360 testing method Methods 0.000 description 8
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 7
239000000463 material Substances 0.000 description 6
238000000034 method Methods 0.000 description 6
230000009477 glass transition Effects 0.000 description 5
238000010438 heat treatment Methods 0.000 description 5
239000007943 implant Substances 0.000 description 5
238000001746 injection moulding Methods 0.000 description 5
XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
238000000137 annealing Methods 0.000 description 4
238000002425 crystallisation Methods 0.000 description 4
230000008025 crystallization Effects 0.000 description 4
238000002513 implantation Methods 0.000 description 4
238000001727 in vivo Methods 0.000 description 4
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
238000010521 absorption reaction Methods 0.000 description 3
239000007795 chemical reaction product Substances 0.000 description 3
230000014759 maintenance of location Effects 0.000 description 3
239000000155 melt Substances 0.000 description 3
238000002156 mixing Methods 0.000 description 3
230000000704 physical effect Effects 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 description 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
229920001634 Copolyester Polymers 0.000 description 2
229920000954 Polyglycolide Polymers 0.000 description 2
229910052786 argon Inorganic materials 0.000 description 2
239000003054 catalyst Substances 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000000465 moulding Methods 0.000 description 2
229920000747 poly(lactic acid) Polymers 0.000 description 2
238000012545 processing Methods 0.000 description 2
238000010926 purge Methods 0.000 description 2
239000000243 solution Substances 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
OORRCVPWRPVJEK-UHFFFAOYSA-N 2-oxidanylethanoic acid Chemical compound OCC(O)=O.OCC(O)=O OORRCVPWRPVJEK-UHFFFAOYSA-N 0.000 description 1
AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 1
230000002411 adverse Effects 0.000 description 1
229920002988 biodegradable polymer Polymers 0.000 description 1
239000004621 biodegradable polymer Substances 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
238000000576 coating method Methods 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
238000001816 cooling Methods 0.000 description 1
238000007334 copolymerization reaction Methods 0.000 description 1
238000005336 cracking Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000007547 defect Effects 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000004821 distillation Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000000605 extraction Methods 0.000 description 1
238000001125 extrusion Methods 0.000 description 1
239000007789 gas Substances 0.000 description 1
230000003301 hydrolyzing effect Effects 0.000 description 1
238000009863 impact test Methods 0.000 description 1
239000012535 impurity Substances 0.000 description 1
238000007373 indentation Methods 0.000 description 1
239000011261 inert gas Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
239000002245 particle Substances 0.000 description 1
239000008188 pellet Substances 0.000 description 1
239000000622 polydioxanone Substances 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
239000004633 polyglycolic acid Substances 0.000 description 1
238000000746 purification Methods 0.000 description 1
239000000376 reactant Substances 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
238000003303 reheating Methods 0.000 description 1
239000013557 residual solvent Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000000859 sublimation Methods 0.000 description 1
230000008022 sublimation Effects 0.000 description 1
KSBAEPSJVUENNK-UHFFFAOYSA-L tin(ii) 2-ethylhexanoate Chemical compound [Sn+2].CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O KSBAEPSJVUENNK-UHFFFAOYSA-L 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
238000012546 transfer Methods 0.000 description 1
239000012780 transparent material Substances 0.000 description 1

Landscapes

Polyesters Or Polycarbonates (AREA)
Materials For Medical Uses (AREA)

CA002079275A 1991-09-30 1992-09-28 Melanges de polymeres de glycolide et de lactide et de homopolymeres et copolymeres poly(p-dioxanone), et sutures resorbables fabriquees a partir de ces materiaux Abandoned CA2079275A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76817791A	1991-09-30	1991-09-30
US07/768,177		1991-09-30

Publications (1)

Publication Number	Publication Date
CA2079275A1 true CA2079275A1 (fr)	1993-03-31

Family

ID=25081771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002079275A Abandoned CA2079275A1 (fr)	1991-09-30	1992-09-28	Melanges de polymeres de glycolide et de lactide et de homopolymeres et copolymeres poly(p-dioxanone), et sutures resorbables fabriquees a partir de ces materiaux

Country Status (1)

Country	Link
CA (1)	CA2079275A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0707044A2 (fr)	1994-10-11	1996-04-17	Ethicon, Inc.	Mélanges de polymères absorbables
CN117982740A (zh) *	2024-04-07	2024-05-07	四川国纳科技有限公司	可吸收生物医用高分子材料、结扎夹及制备方法

1992
- 1992-09-28 CA CA002079275A patent/CA2079275A1/fr not_active Abandoned

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0707044A2 (fr)	1994-10-11	1996-04-17	Ethicon, Inc.	Mélanges de polymères absorbables
US5641501A (en) *	1994-10-11	1997-06-24	Ethicon, Inc.	Absorbable polymer blends
CN117982740A (zh) *	2024-04-07	2024-05-07	四川国纳科技有限公司	可吸收生物医用高分子材料、结扎夹及制备方法
WO2025213703A1 (fr) *	2024-04-07	2025-10-16	四川国纳科技有限公司	Matériau polymère biomédical résorbable, pince de ligature et procédé de préparation associé

Similar Documents

Publication	Publication Date	Title
US5475063A (en)	1995-12-12	Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorbable surgical devices made
US6228954B1 (en)	2001-05-08	Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorabable surgical devices made therefrom
US4744365A (en)	1988-05-17	Two-phase compositions for absorbable surgical devices
EP0667885B1 (fr)	1997-07-16	Composition de polylactide et/ou de glycolide modifiee au caoutchouc
EP0107591B2 (fr)	1999-04-14	Articles chirurgicaux absorbables
AU652761B2 (en)	1994-09-08	Deformable surgical device
CA2459801C (fr)	2012-01-10	Copolymeres poly(l-lactide-co-glycolide), procedes de production et utilisation de ces copolymeres et dispositifs contenant ces copolymeres
US4844854A (en)	1989-07-04	Process for making a surgical device using two-phase compositions
Feng et al.	2009	Biodegradable multiblock copolymers based on oligodepsipeptides with shape‐memory properties
Cai et al.	2000	Synthesis and degradation of a tri-component copolymer derived from glycolide, L-lactide, and ε-caprolactone
US4839130A (en)	1989-06-13	Process of making an absorbable surgical device
CA2035153A1 (fr)	1991-07-31	Copolymeres cristallins de la -dioxanone et de l'¹-caprolac tone
CA2615243A1 (fr)	2007-01-25	Polyetheresters resorbables et leur utilisation pour produire des implants medicaux
US20090234375A1 (en)	2009-09-17	Polymer Material Useful for Medical Devices
Grijpma et al.	1993	Poly (L-lactide) crosslinked with spiro-bis-dimethylene-carbonate
US5124103A (en)	1992-06-23	Two phase compositions for absorbable surgical devices
CA2079274C (fr)	2004-11-30	Melanges de polymeres de glycolide et de lactide et de caprolactone et de polymeres de carbonate de trimethylene, et sutures resorbables fabriquees a partir de ces materiaux
CA2079275A1 (fr)	1993-03-31	Melanges de polymeres de glycolide et de lactide et de homopolymeres et copolymeres poly(p-dioxanone), et sutures resorbables fabriquees a partir de ces materiaux
IE910379A1 (en)	1991-08-14	Segmented copolymers of -caprolactone and glycolide
US7652127B2 (en)	2010-01-26	Absorbable copolyesters of poly(ethoxyethylene diglycolate) and glycolide
TWI312350B (en)	2009-07-21	Biodegradable polyesteramide and preparation method
EP1311581B1 (fr)	2008-09-10	Resine polymere absorbable a haute consistance
US8298260B2 (en)	2012-10-30	Compliant, long-lasting absorbable monofilament sutures
AU2001290515A1 (en)	2002-05-23	High consistency absorbable polymeric resin

Legal Events

Date	Code	Title	Description
1998-09-28	FZDE	Discontinued
2023-05-26	FZDE	Discontinued	Effective date: 19980928