CA2436116A1 - Traitement et prevention des etats associes a l'insulino-resistance cardiaque - Google Patents
Traitement et prevention des etats associes a l'insulino-resistance cardiaque Download PDFInfo
- Publication number
- CA2436116A1 CA2436116A1 CA002436116A CA2436116A CA2436116A1 CA 2436116 A1 CA2436116 A1 CA 2436116A1 CA 002436116 A CA002436116 A CA 002436116A CA 2436116 A CA2436116 A CA 2436116A CA 2436116 A1 CA2436116 A1 CA 2436116A1
- Authority
- CA
- Canada
- Prior art keywords
- insulin resistance
- cardiac
- heart failure
- treatment
- congestive heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procédé de traitement ou de prévention de l'insulino-résistance cardiaque ou des états associés à l'insulino-résistance cardiaque chez les mammaliens humains ou non humains, qui comprend l'administration d'une quantité efficace, non toxique et pharmaceutiquement acceptable d'un agoniste de PPARy tel que le composé (I) ou un dérivé pharmaceutiquement acceptable de celui-ci. Les états associés à l'insulino-résistance cardiaque sont l'angine microvasculaire, l'athérosclérose et l'insuffisance cardiaque globale. Les composés comprennent la rosiglitazone, la troglitazone, l'englitazone et la pioglitazone.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2000/002347 WO2001095906A1 (fr) | 2000-06-16 | 2000-06-16 | Traitement et prevention des etats associes a l'insulino-resistance cardiaque |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2436116A1 true CA2436116A1 (fr) | 2001-12-20 |
Family
ID=9884792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002436116A Abandoned CA2436116A1 (fr) | 2000-06-16 | 2000-06-16 | Traitement et prevention des etats associes a l'insulino-resistance cardiaque |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1292301A1 (fr) |
| JP (1) | JP2004503499A (fr) |
| CN (1) | CN1592620A (fr) |
| AP (1) | AP2002002688A0 (fr) |
| AU (1) | AU2000254153A1 (fr) |
| BG (1) | BG107384A (fr) |
| BR (1) | BR0017254A (fr) |
| CA (1) | CA2436116A1 (fr) |
| DZ (1) | DZ3389A1 (fr) |
| EA (1) | EA200300028A1 (fr) |
| HU (1) | HUP0301103A2 (fr) |
| IL (1) | IL153452A0 (fr) |
| MX (1) | MXPA02012619A (fr) |
| NO (1) | NO20026000L (fr) |
| WO (1) | WO2001095906A1 (fr) |
| YU (1) | YU1203A (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041691B1 (en) | 1999-06-30 | 2006-05-09 | Amgen Inc. | Compounds for the modulation of PPARγ activity |
| US7223761B2 (en) | 2003-10-03 | 2007-05-29 | Amgen Inc. | Salts and polymorphs of a potent antidiabetic compound |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
| US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
| WO1998005331A2 (fr) * | 1996-08-02 | 1998-02-12 | Ligand Pharmaceuticals Incorporated | Prevention ou traitement de diabetes non insulinodependants ou de maladies cardiovasculaires avec des modulateurs ppar |
| WO1999059586A1 (fr) * | 1998-05-19 | 1999-11-25 | Regents Of The University Of California | Derives de thiazolidine et d'oxazolidine pour le traitement d'infarctus du myocarde aigus et pour l'inhibition de l'apoptose des cardiomyocytes |
| MA26662A1 (fr) * | 1998-07-21 | 2004-12-20 | Smithkline Beecham Plc | Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation |
-
2000
- 2000-06-16 EP EP00938933A patent/EP1292301A1/fr not_active Withdrawn
- 2000-06-16 CA CA002436116A patent/CA2436116A1/fr not_active Abandoned
- 2000-06-16 AU AU2000254153A patent/AU2000254153A1/en not_active Abandoned
- 2000-06-16 YU YU1203A patent/YU1203A/sh unknown
- 2000-06-16 BR BR0017254-5A patent/BR0017254A/pt not_active IP Right Cessation
- 2000-06-16 MX MXPA02012619A patent/MXPA02012619A/es unknown
- 2000-06-16 EA EA200300028A patent/EA200300028A1/ru unknown
- 2000-06-16 HU HU0301103A patent/HUP0301103A2/hu unknown
- 2000-06-16 IL IL15345200A patent/IL153452A0/xx unknown
- 2000-06-16 CN CNA008197679A patent/CN1592620A/zh active Pending
- 2000-06-16 DZ DZ003389A patent/DZ3389A1/fr active
- 2000-06-16 WO PCT/GB2000/002347 patent/WO2001095906A1/fr not_active Ceased
- 2000-06-16 JP JP2002510084A patent/JP2004503499A/ja active Pending
- 2000-06-16 AP APAP/P/2002/002688A patent/AP2002002688A0/en unknown
-
2002
- 2002-12-12 BG BG107384A patent/BG107384A/bg unknown
- 2002-12-13 NO NO20026000A patent/NO20026000L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2000254153A1 (en) | 2001-12-24 |
| WO2001095906A1 (fr) | 2001-12-20 |
| JP2004503499A (ja) | 2004-02-05 |
| DZ3389A1 (fr) | 2001-12-20 |
| NO20026000D0 (no) | 2002-12-13 |
| HUP0301103A2 (hu) | 2003-08-28 |
| MXPA02012619A (es) | 2003-04-10 |
| AP2002002688A0 (en) | 2002-12-31 |
| BR0017254A (pt) | 2004-01-06 |
| NO20026000L (no) | 2003-02-11 |
| YU1203A (sh) | 2006-05-25 |
| CN1592620A (zh) | 2005-03-09 |
| EA200300028A1 (ru) | 2003-04-24 |
| EP1292301A1 (fr) | 2003-03-19 |
| BG107384A (bg) | 2003-09-30 |
| IL153452A0 (en) | 2003-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |