CL2015000752A1 - Nuevos ligandos de rig-i y metodos para producirlos - Google Patents

Nuevos ligandos de rig-i y metodos para producirlos

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Publication number
CL2015000752A1
CL2015000752A1 CL2015000752A CL2015000752A CL2015000752A1 CL 2015000752 A1 CL2015000752 A1 CL 2015000752A1 CL 2015000752 A CL2015000752 A CL 2015000752A CL 2015000752 A CL2015000752 A CL 2015000752A CL 2015000752 A1 CL2015000752 A1 CL 2015000752A1
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CL
Chile
Prior art keywords
ligands
produce
methods
new rig
rig
Prior art date
Application number
CL2015000752A
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English (en)
Inventor
Marion Goldeck
Den Boorn Jasper Van
JáNOS LUDWIG
Christine Schubert-Wagner
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Univ Bonn
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Publication date
Application filed by Univ Bonn filed Critical Univ Bonn
Publication of CL2015000752A1 publication Critical patent/CL2015000752A1/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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Abstract

OLIGONUCLEÓTIDO TRIFOSFATO-MODIFICADO QUE PUEDE ACTUAR COMO LIGANDO DE RIG-I; COMPOSICIÓN FARMACÉUTICA QUE LO COMPRENDE; Y MÉTODO DE PREPARACIÓN.
CL2015000752A 2012-09-27 2015-03-25 Nuevos ligandos de rig-i y metodos para producirlos CL2015000752A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12186444.1A EP2712870A1 (en) 2012-09-27 2012-09-27 Novel RIG-I ligands and methods for producing them

Publications (1)

Publication Number Publication Date
CL2015000752A1 true CL2015000752A1 (es) 2015-12-04

Family

ID=46940404

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000752A CL2015000752A1 (es) 2012-09-27 2015-03-25 Nuevos ligandos de rig-i y metodos para producirlos

Country Status (32)

Country Link
US (3) US10059943B2 (es)
EP (5) EP2712870A1 (es)
JP (1) JP6313768B2 (es)
KR (1) KR102182479B1 (es)
CN (2) CN104703996B (es)
AU (2) AU2013322620C1 (es)
BR (2) BR122019023887B1 (es)
CA (1) CA2885564C (es)
CL (1) CL2015000752A1 (es)
CY (1) CY1120660T1 (es)
DK (1) DK2903997T3 (es)
EA (2) EA034605B1 (es)
ES (1) ES2679373T3 (es)
HK (1) HK1214602A1 (es)
HR (1) HRP20181114T1 (es)
HU (1) HUE038811T2 (es)
IL (1) IL237794B (es)
LT (1) LT2903997T (es)
MX (1) MX2015003787A (es)
NZ (2) NZ736108A (es)
PH (1) PH12015500644B1 (es)
PL (1) PL2903997T3 (es)
PT (1) PT2903997T (es)
RS (1) RS57609B1 (es)
SA (2) SA517380700B1 (es)
SG (3) SG10201702028YA (es)
SI (1) SI2903997T1 (es)
TN (1) TN2015000104A1 (es)
TR (1) TR201810231T4 (es)
UA (1) UA117565C2 (es)
WO (1) WO2014049079A1 (es)
ZA (1) ZA201501718B (es)

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JP7366057B2 (ja) 2018-04-19 2023-10-20 チェックメイト ファーマシューティカルズ， インコーポレイテッド 合成ｒｉｇ－ｉ様受容体アゴニスト
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EP3990635A1 (en) 2019-06-27 2022-05-04 Rigontec GmbH Design method for optimized rig-i ligands
US20230242918A1 (en) * 2020-05-22 2023-08-03 President And Fellows Of Harvard College Interferon- inducing oligonucleotide duplexes and methods of use
AU2022302143A1 (en) 2021-07-02 2024-01-18 Yale University Compositions and methods for treating cancers
EP4395832A1 (en) 2021-08-31 2024-07-10 Yale University Compositions and methods for treating cancers
US20230303719A1 (en) 2022-03-03 2023-09-28 Yale University Humanized 3e10 antibodies, variants, and antigen binding fragments thereof
WO2025088117A1 (en) * 2023-10-25 2025-05-01 Rheinische Friedrich-Wilhelms-Universität Bonn Ribonucleic acid construct capable of inducing an immune response, as well as pharmaceutical composition and kit comprising same
WO2025158069A1 (en) 2024-01-25 2025-07-31 Rheinische Friedrich-Wilhelms-Universität Bonn CONSTRUCT COMPRISING mRNA-STRAND AND RETINOIC ACID-INDUCIBLE GENE I (RIG-I)-LIGAND(S), PHARMACEUTICAL COMPOSITION AND KIT COMPRISING THE SAME
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