CN107308039A - 一种抗衰老修复面膜 - Google Patents
一种抗衰老修复面膜 Download PDFInfo
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- CN107308039A CN107308039A CN201710450243.9A CN201710450243A CN107308039A CN 107308039 A CN107308039 A CN 107308039A CN 201710450243 A CN201710450243 A CN 201710450243A CN 107308039 A CN107308039 A CN 107308039A
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- facial mask
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Abstract
本发明公开了一种抗衰老修复面膜，包括毛叶香茶菜二萜、密蒙花黄酮、木棉花黄酮、甘油、丁二醇、甜菜碱、海藻糖、烟酰胺等成分。面膜中添加天然的毛叶香茶菜二萜、密蒙花黄酮和密蒙花黄酮活性成分，能有效中断过氧化链式反应，清除游离自由基，鳌合金属离子，并调节炎症细胞，达到延缓细胞衰老，修复并预防细胞损伤的功效；另外，密蒙花黄酮能激活其修复基因，促进损伤部位的修复，防止炎症扩大或持续过长，结合毛叶香茶菜调节此过程中激酶与信号素的分泌与转移，间接调节修复和炎症的发生，并调节生物膜流动性，从而增强真皮弹性纤维，稳定细胞结构，达到显著的修复效果；本发明的面膜还能起到保湿、补水和美白作用。
Description
技术领域
本发明涉及化妆品领域，具体涉及一种抗衰老修复面膜。
背景技术
衰老又称为老化，是生命活性中必经阶段。长期受紫外线照射是 导致皮肤衰老的最常见和作用最强的外在因素。紫外线损害的积累造 成皮肤的衰老被称为“光老化”。光老化的特征变化限于光暴露部位， 表现为皮肤暴露部位粗糙略显肥厚、皱纹加深加粗、皮肤角质增厚、 不规则性色素沉着、毛细血管扩张或消失、表皮角化不良及真皮弹性 纤维变性等。目前人们生活比较安定富足，对外貌表观的美化要求 越来越高，因此，抗衰老护肤将是将来一个持续的发展趋势。国内抗 衰老市场已经基本成熟，但其相关产品及服务的发展空间十分巨大。
植物活性成分应用于化妆品已经很常见，但是针对面部抗衰老修 复，且效果显著的面膜较少。
发明内容
基于此，本发明的目的在于提供一种抗衰老修复面膜，有较好的 保湿、滋润效果，还能达到显著的抗衰老修复作用。并提供面膜的制 备方法。
为了达到上述目的，本发明提供如下的技术方案：
一种抗衰老修复面膜包括质量百分比为0.3-6％的植物组合物；其 中，所述植物组合物由毛叶香茶菜二萜、密蒙花黄酮、木棉花黄酮组 成，且毛叶香茶菜二萜、密蒙花黄酮、木棉花黄酮的重量比为 (0.1-2):(0.1-2):(0.1-2)。
所述毛叶香茶菜二萜的制备方法包括以下步骤：将毛叶香茶菜洗 净烘干，粉碎过40-60目筛，按料液比1:10-20加入50-80％乙醇浸泡 过夜，超声提取10-30min，提取频率80-120Hz，温度40-60℃，提取 3次，过滤，合并滤液后减压浓缩干燥，得到毛叶香茶菜二萜。
所述密蒙花黄酮的制备方法包括以下步骤：将密蒙花洗净干燥， 粉碎过40-60目筛，按料液比1:20-30加入50-70％乙醇，于45-65℃ 条件下恒温水浴提取1-3h，过滤，滤液经减压浓缩干燥，得到密蒙花 黄酮。
所述木棉花黄酮的制备方法包括以下步骤：将木棉花洗净干燥， 粉碎过40-60目筛，按料液比1:25-35加入50-70％乙醇，超声提取 20-40min，超声功率400-500W，温度20-40℃，过滤，滤液经减压浓 缩干燥，得到木棉花黄酮。
所述面膜还包括以下成分：甘油2-8％、丁二醇10-20％、甜菜碱 1-6％、海藻糖2-6％、烟酰胺0.05-0.2％、羟苯甲酯0.5-2％、泛醇0.5-1.5、 尿囊素0.1-0.5％、纤维素0.2-1％、透明质酸钠0.05-0.1％、黄原胶 0.01-0.1％、芦芭胶0.1-0.5％、苯氧乙醇0.3-1％、去离子水余量。
本发明还提供一种抗衰老修复面膜的制备方法，包括以下步骤： (1)将甘油、丁二醇、甜菜碱、海藻糖、烟酰胺、黄原胶、羟苯甲 酯、泛醇、尿囊素、纤维素、透明质酸钠、芦芭胶、去离子水，加入 搅拌锅中加热至80-85℃，搅拌溶解完全；
(2)降温至45-55℃，加入上述植物组合物、苯氧乙醇，搅拌至溶解 完全、冷却出料。
对本发明的植物活性成分作如下介绍：
毛叶香茶菜提取物包括萜类化合物、苯丙素、甾体类等多种活性 成分。毛叶香茶菜中丰富的二萜类化合物能有效抑制微生物繁殖，其 原因为二萜化合物的结构单元能与微生物活性基团结合，进而产生抗 菌活性；能通过调节激酶和信号素，进而可以间接调节各种炎症。对 于细胞氧化损伤，二萜类化合物能减少脂质过氧化引起的不良产物积 累，预防进一步的过氧化链式反应，同时能延缓衰老细胞的生物膜流 动性下降，有效清除过量的自由基，进一步减少氧化损伤。
密蒙花提取物含有黄酮类、苯乙醇苷类、皂苷类、环烯醚萜类等 活性物质。其中黄酮类为主要活性物质。密蒙花黄酮能激活细胞修复 相关基因，同时抑制过度表达的炎症基因，能有效修复受损细胞并防 止损伤扩大。由于密蒙花黄酮含有多个强还原基团，能作为氢供体提 供出游离质子，与自由基结合，减少游离自由基对细胞内其他物质与 结构造成损伤。
木棉花提取物具有多种功能活性成分，如黄酮、多酚、多糖、花 青素及各种矿物质元素，具有消炎抗微生物、预防细胞损伤，抗氧化 抗衰老等功效，其中主要活性物质为木棉花黄酮。木棉花中的黄酮类 化合物含量较髙，具有较强的抗氧化活性，对体内的自由基有较强的 清除作用。木棉花黄酮中，含有丰富的酚羟基，能有效提高抗氧化酶 的活性，同时降低脂质过氧化产物的含量。此外木棉花黄酮与金属离 子能发生鳌合作用，形成稳定螯合物，防止金属离子与细胞内其他物 质互相影响产生自由基。
与现有技术相比，本发明的有益效果如下：(1)本发明的面膜中 添加天然的毛叶香茶菜二萜、密蒙花黄酮和密蒙花黄酮活性成分，能 有效中断过氧化链式反应，清除游离自由基，鳌合金属离子，并调节 炎症细胞，达到延缓细胞衰老，修复并预防细胞损伤的功效；(2)另 外，密蒙花黄酮能激活其修复基因，促进损伤部位的修复，防止炎症 扩大或持续过长，结合毛叶香茶菜调节此过程中激酶与信号素的分泌 与转移，间接调节修复和炎症的发生，并调节生物膜流动性，从而增 强真皮弹性纤维，稳定细胞结构，达到显著的修复效果；(3)本发明 的面膜不仅能抗衰老，修复肌肤，还能起到保湿、补水和美白作用； (4)本发明的面膜安全、温和，各项卫生指标和和感官指标皆理想。
具体实施方式
以下结合具体实施例对本发明作进一步阐述。
本发明实施例1-5本发明抗衰老修复面膜配方见表1
表1
上述毛叶香茶菜二萜的制备方法包括以下步骤：
将毛叶香茶菜洗净烘干，粉碎过40目筛，按料液比1:15加入70％乙 醇浸泡过夜，超声提取20min，提取频率100Hz，温度50℃，提取3 次，过滤，合并滤液后减压浓缩干燥，得到毛叶香茶菜二萜。
上述密蒙花黄酮的制备方法包括以下步骤：
将密蒙花洗净干燥，粉碎过40目筛，按料液比1:25加入70％乙醇， 于60℃条件下恒温水浴提取2h，过滤，滤液经减压浓缩干燥，得到 密蒙花黄酮。
上述木棉花黄酮的制备方法包括以下步骤：
将木棉花洗净干燥，粉碎过40目筛，按料液比1:30加入70％乙醇， 超声提取30min，超声功率450W，温度40℃，过滤，滤液经减压浓 缩干燥，得到木棉花黄酮。
实施例1-5一种抗衰老修复面膜的制备方法包括以下步骤：
(3)将甘油、丁二醇、甜菜碱、海藻糖、烟酰胺、黄原胶、羟苯甲 酯、泛醇、尿囊素、纤维素、透明质酸钠、芦芭胶、去离子水，加入 搅拌锅中加热至85℃，搅拌溶解完全；
(4)降温至50℃，加入上述植物组合物、苯氧乙醇，搅拌至溶解完 全、冷却出料。
对比例1
与实施例1的区别是未加入毛叶香茶菜二萜，其他制备条件和方法与 实施例1相同。
对比例2
与实施例1的区别是未加入密蒙花黄酮，其他制备条件和方法与实施 例1相同。
对比例3
与实施例1的区别是未加入木棉花黄酮，其他制备条件和方法与实施 例1相同。
对比例4
与实施例1的区别是未加入植物组合物，其他制备条件和方法与实施
例1相同。
抗炎症能力测试
皮肤抗炎测试：通过肉眼观察，选取皮肤被蚊虫叮咬出现发炎现象的 患者，观察使用效果。选取150个试用者，在湿度相同的环境中，分 为10组，每组15人，分别采用一组对照组(市售的宣称具有抗炎功 效的面膜)，9组实验组(实施例1-5和对比例1-4)，每日使用两次， 每次一小时，三天后测试结果如表2所示
表2
| 组别 | 总人数/人 | 痊愈人数/人 | 明显缓解人数/人 | 无明显缓解人数/人 |
| 实施例1 | 15 | 11 | 3 | 1 |
| 实施例2 | 15 | 9 | 4 | 2 |
| 实施例3 | 15 | 9 | 5 | 1 |
| 实施例4 | 15 | 10 | 3 | 2 |
| 实施例5 | 15 | 10 | 4 | 1 |
| 对比例1 | 15 | 4 | 6 | 5 |
| 对比例2 | 15 | 5 | 6 | 4 |
| 对比例3 | 15 | 4 | 5 | 6 |
| 对比例4 | 15 | 0 | 0 | 15 |
| 对照组 | 15 | 4 | 5 | 6 |
上表数据表明实施例1-5的抗炎症能力明显高于对比例和对照组，可 见本发明抗衰老修复面膜中添加的植物组合物具有优异的抗炎症能 力，三种成分协同发挥功效，调节炎症细胞，促进损伤部位的修复。 保湿抗衰老功效试验
选取15-60岁的志愿者150名，分为10组，每组15人，分别采用一 组对照组(市售的宣称具有保湿抗衰老功效的面膜)，9组实验组(实 施例1-5和对比例1-4)，每晚洁面后使用，并加以适当按摩，连续坚 持使用30天，观察记录皮肤情况，结果如表3所示
表3
从表3结果可知，实施例1-5和对比例1-4制得的本发明抗衰老修复 面膜对皮肤均匀不同程度的保湿补水、抗衰老效果。从实验数据来看， 实施例1-5的效果均优于对比例和对照组面膜，对比例4为在与实施 例1配方其他成分相同的情况下未添加植物组合物的抗衰老修复面 膜，从数据中可见其效果明显下降。由此可见，添加植物组合物的本 发明抗衰老修复面膜，对皮肤具有较佳的抗衰老，保湿，修复功效。 以上实施例仅说明本发明的实施方案，并没有对本发明有任何形式上 的限制；任何从事本专业的技术人员，都有能力利用揭示的技术内容 作出一些更动或修饰，成为等同变化的等效实施例，根据本发明技术 实质，对本发明进行简单修改、等同变化与修饰，均属于本发明技术 方案的范围内。
Claims (7)
1.一种抗衰老修复面膜，其特征在于，所述面膜包括质量百分比为0.3-6％的植物组合物；
其中，所述植物组合物由毛叶香茶菜二萜、密蒙花黄酮、木棉花黄酮组成。
2.根据权利要求1所述的一种抗衰老修复面膜，其特征在于，所述毛叶香茶菜二萜、密蒙花黄酮、木棉花黄酮的重量比为(0.1-2):(0.1-2):(0.1-2)。
3.根据权利要求1所述的一种抗衰老修复面膜，其特征在于，所述毛叶香茶菜二萜的制备方法包括以下步骤：
将毛叶香茶菜洗净烘干，粉碎过40-60目筛，按料液比1:10-20加入50-80％乙醇浸泡过夜，超声提取10-30min，提取频率80-120Hz，温度40-60℃，提取3次，过滤，合并滤液后减压浓缩干燥，得到毛叶香茶菜二萜。
4.根据权利要求1所述的一种抗衰老修复面膜，其特征在于，所述密蒙花黄酮的制备方法包括以下步骤：
将密蒙花洗净干燥，粉碎过40-60目筛，按料液比1:20-30加入50-70％乙醇，于45-65℃条件下恒温水浴提取1-3h，过滤，滤液经减压浓缩干燥，得到密蒙花黄酮。
5.根据权利要求1所述的一种抗衰老修复面膜，其特征在于，所述木棉花黄酮的制备方法包括以下步骤：
将木棉花洗净干燥，粉碎过40-60目筛，按料液比1:25-35加入50-70％乙醇，超声提取20-40min，超声功率400-500W，温度20-40℃，过滤，滤液经减压浓缩干燥，得到木棉花黄酮。
6.根据权利要求1所述的一种抗衰老修复面膜，其特征在于，所述面膜还包括以下成分：
甘油2-8％、丁二醇10-20％、甜菜碱1-6％、海藻糖2-6％、烟酰胺0.05-0.2％、羟苯甲酯0.5-2％、泛醇0.5-1.5、尿囊素0.1-0.5％、纤维素0.2-1％、透明质酸钠0.05-0.1％、黄原胶0.01-0.1％、芦芭胶0.1-0.5％、苯氧乙醇0.3-1％、去离子水余量。
7.一种如权利要求1-6任一项所述抗衰老修复面膜的制备方法，其特征在于，包括以下步骤：
(1)将甘油、丁二醇、甜菜碱、海藻糖、烟酰胺、黄原胶、羟苯甲酯、泛醇、尿囊素、纤维素、透明质酸钠、芦芭胶、去离子水，加入搅拌锅中加热至80-85℃，搅拌溶解完全；
(2)降温至45-55℃，加入如权利要求1所述植物组合物、苯氧乙醇，搅拌至溶解完全、冷却出料。
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