CN108558724A - 视黄醇酯的酯交换方法 - Google Patents

视黄醇酯的酯交换方法 Download PDF

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Publication number
CN108558724A
CN108558724A CN201810319627.1A CN201810319627A CN108558724A CN 108558724 A CN108558724 A CN 108558724A CN 201810319627 A CN201810319627 A CN 201810319627A CN 108558724 A CN108558724 A CN 108558724A
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CN
China
Prior art keywords
transesterification
formula
compound
alcohol
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810319627.1A
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English (en)
Chinese (zh)
Inventor
沃纳尔·邦拉蒂
亚历克斯·贾俄
克劳德·斯特里特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
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DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48918423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN108558724(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of CN108558724A publication Critical patent/CN108558724A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CN201810319627.1A 2012-08-07 2013-08-07 视黄醇酯的酯交换方法 Pending CN108558724A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12179461.4 2012-08-07
EP12179461 2012-08-07
CN201380041720.6A CN104520270A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380041720.6A Division CN104520270A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Publications (1)

Publication Number Publication Date
CN108558724A true CN108558724A (zh) 2018-09-21

Family

ID=48918423

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201810319627.1A Pending CN108558724A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法
CN201380041720.6A Pending CN104520270A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201380041720.6A Pending CN104520270A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Country Status (6)

Country Link
US (1) US9371279B2 (2)
EP (1) EP2882709B1 (2)
CN (2) CN108558724A (2)
EA (1) EA027565B1 (2)
IN (1) IN2015DN00725A (2)
WO (1) WO2014023772A1 (2)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544391B (zh) * 2016-11-25 2019-10-18 厦门金达威维生素有限公司 酶催化制备维生素a棕榈酸酯的方法
CN108623507A (zh) * 2017-03-15 2018-10-09 四川海思科制药有限公司 维生素a棕榈酸酯的制备方法
EP4126796A1 (en) * 2020-03-31 2023-02-08 DSM IP Assets B.V. Process for production of terpenoid-intermediates
CN112522331B (zh) * 2020-12-09 2024-03-22 上海克琴科技有限公司 一种生物酶催化的羟基频哪酮视黄酸酯的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971966A (en) * 1957-08-30 1961-02-14 Pfizer & Co C Process of preparing vitamin a esters
US3287382A (en) * 1962-04-27 1966-11-22 Philips Corp Vitamin a acid ester of vitamin a
WO2004044212A1 (en) * 2002-11-11 2004-05-27 Unilever Plc Method of producing retinyl esters
CN101553574A (zh) * 2006-10-06 2009-10-07 伊士曼化工公司 制备视黄酯的方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971966A (en) * 1957-08-30 1961-02-14 Pfizer & Co C Process of preparing vitamin a esters
US3287382A (en) * 1962-04-27 1966-11-22 Philips Corp Vitamin a acid ester of vitamin a
WO2004044212A1 (en) * 2002-11-11 2004-05-27 Unilever Plc Method of producing retinyl esters
CN101553574A (zh) * 2006-10-06 2009-10-07 伊士曼化工公司 制备视黄酯的方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MILAN SOUKUP等: "PREPARATION OF (7Z)- AND (7Z,11Z)-VITAMIN A", 《TETRAHEDRON LETTERS》 *

Also Published As

Publication number Publication date
EP2882709A1 (en) 2015-06-17
IN2015DN00725A (2) 2015-07-10
EA027565B1 (ru) 2017-08-31
WO2014023772A1 (en) 2014-02-13
EA201500210A1 (ru) 2015-07-30
EP2882709B1 (en) 2018-06-20
US20150183734A1 (en) 2015-07-02
CN104520270A (zh) 2015-04-15
US9371279B2 (en) 2016-06-21

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Application publication date: 20180921

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