CN112129961B - Reaction vessel supply device and reaction vessel supply method - Google Patents

Reaction vessel supply device and reaction vessel supply method

Info

Publication number
CN112129961B
CN112129961B CN202011001581.2A CN202011001581A CN112129961B CN 112129961 B CN112129961 B CN 112129961B CN 202011001581 A CN202011001581 A CN 202011001581A CN 112129961 B CN112129961 B CN 112129961B
Authority
CN
China
Prior art keywords
conveying
reaction vessel
supply
reaction
conveying device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202011001581.2A
Other languages
Chinese (zh)
Other versions
CN112129961A (en
Inventor
张少鹏
龚伟
张珥
高智诚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maccura Medical Electronics Co Ltd
Original Assignee
Maccura Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maccura Medical Electronics Co Ltd filed Critical Maccura Medical Electronics Co Ltd
Priority to CN202011001581.2A priority Critical patent/CN112129961B/en
Publication of CN112129961A publication Critical patent/CN112129961A/en
Priority to PCT/CN2021/119715 priority patent/WO2022063141A1/en
Application granted granted Critical
Publication of CN112129961B publication Critical patent/CN112129961B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

本发明涉及一种反应容器供给装置及反应容器供给方法,该反应容器供给装置包括:固定架,包括至少两个安装板;至少两个输送装置,分别与至少两个安装板一一对应地可移动连接;每个输送装置包括相对设置的一对导向板件,一对导向板件之间形成供给通道,输送装置通过供给通道供给多个反应容器;控制器,用于监测当前处于工作模式的一个输送装置供给反应容器的运行状态;当运行状态为异常时,关闭当前输送装置,并启动至少两个输送装置中的另一个输送装置以继续供给反应容器。本发明可以连续供给反应容器,减少停机处理异常问题的时间,提高整机工作效率。

This invention relates to a reaction vessel supply device and method. The reaction vessel supply device includes: a fixed frame comprising at least two mounting plates; at least two conveying devices, each movably connected to one of the at least two mounting plates; each conveying device including a pair of guide plates arranged opposite each other, forming a supply channel between the pair of guide plates, through which the conveying devices supply multiple reaction vessels; and a controller for monitoring the operating status of one conveying device currently in operation, supplying reaction vessels; when the operating status is abnormal, shutting down the current conveying device and activating another of the at least two conveying devices to continue supplying reaction vessels. This invention can continuously supply reaction vessels, reducing downtime for handling abnormal problems and improving overall machine efficiency.

Description

Reactor supply device and reactor supply method
Technical Field
The present invention relates to the field of medical diagnosis technology, and more particularly, to a reaction vessel supply device and a reaction vessel supply method.
Background
In the field of medical diagnosis, when a body fluid sample such as blood or urine is subjected to detection and analysis, the sample and a reaction reagent must be loaded together in a reaction container and then detected. The steps of supplying, loading samples and reaction reagents from the reaction container, detecting, analyzing, recovering the waste reaction container and the like need to be carried through a production line so as to realize batch detection and analysis operation. The existing reaction vessel supply device is independently arranged, and is required to be shut down for maintenance when faults occur, so that the detection and analysis efficiency of the whole machine is greatly reduced.
Disclosure of Invention
The invention aims to provide a reaction vessel supply device and a reaction vessel supply method, wherein the reaction vessel supply device can continuously supply reaction vessels, and is beneficial to improving the working efficiency of the whole machine.
On one hand, the invention provides a reaction vessel supply device which comprises a fixing frame, at least two conveying devices, a controller and a control device, wherein the fixing frame comprises at least two mounting plates, the at least two conveying devices are respectively and correspondingly movably connected with the at least two mounting plates one by one, each conveying device comprises a pair of guide plates which are oppositely arranged, a supply channel is formed between the pair of guide plates, the conveying devices supply a plurality of reaction vessels through the supply channel, the controller is used for monitoring the running state of one conveying device which is in a working mode at present and supplies the reaction vessels, and when the running state is abnormal, the current conveying device is closed, and the other conveying device of the at least two conveying devices is started to continue supplying the reaction vessels.
According to one aspect of the embodiment of the invention, the supply channel of each conveying device is provided with a feeding position and a discharging position along the length direction of the supply channel, and the guide plate is provided with a first sensor corresponding to the discharging position and used for sending a first signal to the controller when the reaction container reaches the discharging position and sending a second signal to the controller when the reaction container is taken away.
According to an aspect of the embodiment of the present invention, the controller is further configured to count the number of times the first signal is sent by the first sensor of the conveying device currently in the operation mode, and determine that the operation state of the current conveying device is abnormal when the number of times the first signal is equal to the supply threshold value of the reaction container.
According to an aspect of the embodiment of the present invention, the controller is further configured to determine that the current operation state of the conveying device is abnormal when the first signal or the second signal sent by the first sensor of the conveying device currently in the operation mode is not received within a predetermined time.
According to one aspect of the embodiment of the invention, the fixing frame further comprises a bottom plate, the bottom plate is used for supporting at least two conveying devices, a first magnetic piece is arranged at one end of the bottom plate corresponding to the supply channel, a second magnetic piece and a second sensor are arranged on the guide plate, and after the conveying devices move to a preset position along the mounting plate, the first magnetic piece and the second magnetic piece are adsorbed together and trigger the second sensor to send a third signal to the controller.
According to one aspect of the embodiment of the invention, one end of the bottom plate corresponding to the supply channel is further provided with a fixing piece, the fixing piece is provided with a positioning pin, the guide plate is correspondingly provided with a pin hole matched with the positioning pin, and after the conveying device moves to a preset position along the mounting plate, the positioning pin stretches into the pin hole.
According to one aspect of the embodiment of the invention, each conveying device comprises a supporting plate movably connected with a mounting plate, a pair of guide plates fixedly connected with the supporting plate, a rotary table rotatably connected with the supporting plate and comprising a rotary shaft and a pair of disc bodies coaxially connected with the rotary shaft and arranged at intervals, a conveyor belt, one end of the conveyor belt is wound on the rotary shaft between the pair of disc bodies, a plurality of reaction containers which are sequentially arranged are arranged along the length direction of the conveyor belt and are positioned on one side of the conveyor belt, which is away from the rotary shaft, and a rotary wheel assembly connected with the supporting plate and arranged between the rotary table and the guide plates, wherein the other end of the conveyor belt is wound on the rotary wheel assembly and used for guiding the reaction containers on the conveyor belt into a supply channel.
According to one aspect of the embodiment of the invention, the rotating wheel assembly comprises a driving motor, a driving rotating wheel, a first guide wheel and a second guide wheel, wherein the driving motor is electrically connected with the controller and is rotatably connected with the supporting plate, the driving rotating wheel is coaxially connected with an output shaft of the driving motor, an annular groove is formed in the driving rotating wheel, the other end of the conveying belt is wound on the annular groove, the first guide wheel and the second guide wheel are respectively positioned between the rotating wheel and the driving rotating wheel and are in friction contact with the conveying belt, the first guide wheel is close to the rotating wheel and is used for guiding the conveying belt into the supply channel, and the second guide wheel is positioned on one side, away from the rotating wheel, of the first guide wheel and is positioned above the supply channel and is used for separating the reaction container from the conveying belt.
According to one aspect of the embodiment of the invention, a first central connecting line between the central axis of the first guide wheel and the central axis of the second guide wheel is L1, a second central connecting line between the central axis of the second guide wheel and the central axis of the driving wheel is L2, and an included angle θ between the first central connecting line L1 and the second central connecting line is not less than 90 °.
According to one aspect of the embodiment of the invention, the reaction vessel is provided with oppositely arranged lugs connected with the conveyor belt, the side of each guide plate facing the supply channel is provided with inwards concave grooves, and the width dimension d1 between the oppositely arranged lugs is larger than the width dimension d2 of the conveyor belt and smaller than the distance d3 between the pair of grooves.
According to an aspect of the embodiment of the invention, the reaction vessel supply device further includes a cover assembly including a cover plate covering the supply passage between the second guide wheel and the discharge position, and a protruding portion provided at a side of the cover plate facing the supply passage, and the protruding portion is telescopically inserted into the supply passage under the second guide wheel.
According to one aspect of the embodiment of the invention, the supporting plate is provided with a convex column and a lock pin which is rotatably connected with the convex column corresponding to the rotating shaft of the turntable, the rotating shaft is sleeved on the periphery side of the convex column and is pressed on one of the disk bodies through the lock pin, and an elastic piece is arranged between the other disk body and the supporting plate.
On the other hand, the invention also provides a reaction vessel supply method of the reaction vessel supply device, which comprises the steps of acquiring the running state information of the conveying device in the current working mode for supplying the reaction vessel, sending a stop signal to the current conveying device when the running state information is abnormal, and starting the other conveying device of the at least two conveying devices to continuously supply the reaction vessel.
According to the reaction container supply device and the reaction container supply method, at least two conveying devices capable of being pushed and pulled are arranged, when one conveying device is used for supplying the reaction container abnormally, the other conveying device can be replaced, so that the reaction container can be continuously supplied, the time for stopping the machine to treat the abnormal problem is reduced, and the working efficiency of the whole machine is improved. In addition, the reaction vessel supply device has compact overall structure, saves space and is beneficial to being arranged in the assembly line detection and analysis equipment.
Drawings
Features, advantages, and technical effects of exemplary embodiments of the present invention will be described below with reference to the accompanying drawings. In the drawings, like parts are designated with like reference numerals. The figures are not drawn to scale.
FIG. 1 is a schematic perspective view of a reaction vessel supply apparatus according to an embodiment of the present invention;
FIG. 2 is a schematic side view of the reaction vessel supplying apparatus shown in FIG. 1 in the direction A;
FIG. 3 is a partially enlarged schematic view of the region D of the reaction vessel supply apparatus shown in FIG. 2;
FIG. 4 is a partially enlarged schematic view of the region B of the reaction vessel supply apparatus shown in FIG. 1;
FIG. 5 is a schematic view showing the structure of a conveyor in the reaction vessel supplying apparatus shown in FIG. 1;
FIG. 6 is an exploded view of the delivery device shown in FIG. 5;
FIG. 7 is a schematic view showing an assembled structure of a reaction vessel and a conveyor belt in the reaction vessel supplying apparatus shown in FIG. 5;
FIG. 8 is a schematic top view of a cap assembly in the reaction vessel supply apparatus shown in FIG. 5;
FIG. 9 is a schematic view showing a back surface structure of a cap assembly in the reaction vessel supplying apparatus shown in FIG. 5;
FIG. 10 is a block flow diagram of a method for supplying a reaction vessel according to an embodiment of the present invention.
Reference numerals illustrate:
1-fixing frame, 11-mounting plate, 111-guide rail, 112-sliding block, 12-bottom plate, 121-first magnetic piece, 122-fixing piece, 123-locating pin, C-reaction container, E-ear, C1-container body, C2-fixing column and O-magnetic bead;
2-conveying device, 20-guide plate, 21-supply channel, P1-feeding position, P2-discharging position, 201-first sensor, 202-second sensor, 203-second magnetic piece, 204-pin hole, 205-groove, 22-support plate, 221-convex column, 222-lock pin, 223-bending part, 23-rotary disk, 231-rotary shaft, 232-disk body, 24-conveyer belt, 25-rotary wheel assembly, 251-driving motor, 252-driving rotary wheel, 252 a-annular groove, 253-first guide wheel, 254-second guide wheel and 26-elastic piece;
3-cap assembly, 31-cap plate, 311-blind slot, 32-extension, 33-toggle, 34-hinge.
Detailed Description
Features and exemplary embodiments of various aspects of the invention are described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of the invention. It will be apparent, however, to one skilled in the art that the present invention may be practiced without some of these specific details. The following description of the embodiments is merely intended to provide a better understanding of the invention by showing examples of the invention. In the drawings and the following description, at least some well-known structures and techniques have not been shown in order to avoid unnecessarily obscuring the present invention, and the dimensions of some of the structures may be exaggerated for clarity. Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.
The directional terms appearing in the following description are directions shown in the drawings and do not limit the specific structure of the reaction vessel supply apparatus of the present invention. In the description of the present invention, it should also be noted that, unless explicitly specified and limited otherwise, the terms "mounted" and "connected" are to be construed broadly, and may be fixedly connected, detachably connected, integrally connected, directly connected, or indirectly connected, for example. The specific meaning of the above terms in the present invention can be understood as appropriate by those of ordinary skill in the art.
In order to better understand the present invention, a reaction vessel supply apparatus and a reaction vessel supply method according to embodiments of the present invention will be described in detail with reference to fig. 1 to 10.
Referring to fig. 1 to 3, the present invention provides a reaction vessel supplying apparatus, which includes a fixing frame 1, at least two conveying devices 2 and a controller (not shown).
The fixing frame 1 comprises at least two mounting plates 11, and at least two conveying devices 2 are respectively movably connected with the at least two mounting plates 11 in a one-to-one correspondence. Each of the conveying devices 2 includes a pair of guide plates 20 disposed opposite to each other, a supply passage 21 is formed between the pair of guide plates 20, and the conveying device 2 supplies a plurality of reaction containers C through the supply passage 21.
The conveying device 2 may be movably connected with the mounting plate 11 through a moving device, and the moving device may include, for example, a guide rail 111 and a slider 112 slidably connected with the guide rail 111, where the guide rail 111 is fixedly connected with the mounting plate 11, the conveying device 2 is fixedly connected with the slider 112, and an extending direction of the guide rail 111 is a moving direction of the conveying device 2. The conveying device 2 is movably arranged relative to the mounting plate 11, so that the conveying device 2 is conveniently pulled out of the fixing frame 1 to carry out overhaul, maintenance, loading of the reaction container C and the like, and then the conveying device 2 is pushed to the fixing frame 1.
In order to increase the stability of the fixing of the conveyor devices 2, two moving devices may be provided, which are spaced apart in the height direction of each conveyor device 2. In order to reduce the weight of the fixing frame 1 and improve the rigidity of the fixing frame 1, the mounting plate 11 can be partially hollowed out, and will not be described again. In addition, the number of the conveying devices 2 is at least two, one conveying device 2 is in the current working mode, and the rest conveying devices 2 are standby. The at least two conveying devices 2 are each movably connected to at least two mounting plates 11 in a one-to-one correspondence.
The controller is used for monitoring the running state of one conveying device 2 in the current working mode for supplying the reaction container C, and when the running state is abnormal, the current conveying device 2 is closed, and the other conveying device 2 in the at least two conveying devices 2 is started to continuously supply the reaction container C. The controller may be provided at any position, for example, fixed to the holder 1, or may be fixed to a position other than the reaction vessel supply device.
When the controller judges that the operation state of one of the conveying devices 2 currently in the operation mode is abnormal, the current conveying device 2 may be turned off and the other conveying device 2 may be started to continue supplying the reaction vessel C. The closed conveying device 2 can be pulled out from the fixing frame 1 to carry out maintenance work such as overhaul and the like, and the closed conveying device 2 is pushed into the original position after the maintenance is completed to serve as a standby conveying device 2. The whole maintenance process does not influence the normal operation of the other conveying device 2, so that the reaction container C can be continuously supplied, the time for stopping the machine to treat abnormal problems is reduced, and the working efficiency of the whole machine is improved.
Optionally, at least two mounting plates 11 of the fixing frame 1 are arranged in parallel, so that at least two conveying devices 2 are arranged side by side, and when the fixing frame is applied to a production line of sample analysis equipment, a manipulator can conveniently move to a supply channel 21 of any designated conveying device 2 along the same direction perpendicular to the side by side direction, a reaction container C is grasped, the movement path of the manipulator is simplified, and the detection efficiency of the sample analysis equipment is improved.
According to the reaction container supply device provided by the embodiment of the invention, by arranging at least two conveying devices 2 capable of being pushed and pulled to move, when one conveying device 2 supplies the reaction container abnormally, the other conveying device 2 can be replaced, so that the reaction container C can be continuously supplied, the time for stopping the machine to treat the abnormal problem is reduced, and the working efficiency of the whole machine is improved. In addition, the reaction vessel supply device has compact overall structure, saves space and is beneficial to being arranged in the assembly line detection and analysis equipment.
The specific structure of a reaction vessel supply apparatus according to an embodiment of the present invention is described in further detail below with reference to the accompanying drawings. For convenience of description, the embodiment of the present invention will be described by taking an example in which the reaction vessel supplying apparatus includes two transporting apparatuses 2.
Referring to fig. 1 and 4 together, the supply channel 21 of each conveyor 2 has a feeding position P1 and a discharging position P2 along its length, and the guide plate 20 is provided with a first sensor 201 corresponding to the discharging position P2 for sending a first signal to the controller when the reaction container C reaches the discharging position P2 and a second signal to the controller when the reaction container C is removed.
Alternatively, the first sensor 201 is a photosensor. The first signal indicates that the reaction container C has reached the discharging position P2, and at this time, the controller may control the conveying device 2to suspend conveying the reaction container C, so as to facilitate a manipulator or a manual removal of the reaction container C. The second signal indicates that the reaction vessel C at the discharge position P2 is empty, which means that the reaction vessel C has been removed, and the controller can control the conveying device 2to continue conveying the next reaction vessel C.
As an alternative embodiment, the controller is further configured to count the number of times the first signal is sent by the first sensor 201 of the conveying device 2 currently in the operation mode, and determine that the current operation state of the conveying device 2 is abnormal when the number of times the first signal is equal to the supply threshold value of the reaction container C.
The number of times the first signal is transmitted by the first sensor 201 is the number of reaction containers C that have been supplied to the discharging position P2. The supply threshold of the reaction containers C refers to a threshold of the number of the reaction containers C that have been supplied in place, which may be, for example, 99.5% of the total number. For example, if the total number of reaction containers C that the conveying device 2 can supply is 1000, the supply threshold is 995. When the number of times of the first signal transmitted from the first sensor 201 is equal to the supply threshold value of the reaction container C, the controller determines that the current operation state of the conveyor device 2 is abnormal, and needs to switch to another conveyor device 2 and reload the reaction container C for that conveyor device 2.
As an alternative embodiment, the controller is further configured to determine that the current operation state of the conveying device 2 is abnormal when the first signal or the second signal sent by the first sensor 201 of the conveying device 2 currently in the operation mode is not received within a predetermined time.
If the controller does not receive the first signal or the second signal within the predetermined time, for example, the predetermined time is 1s, which indicates that the reaction vessel C may be jammed due to a failure of the conveying device 2, the controller determines that the current operation state of the conveying device 2 is abnormal, and needs to switch to another conveying device 2, and eliminates a failure problem of the conveying device 2.
As described above, when the controller determines that the current operation state of the conveyor 2 is abnormal, the conveyor 2 needs to be pulled out from the holder 1 along the moving device for maintenance, and the conveyor 2 is pushed to the holder 1 after the maintenance is completed. At this time, it is necessary to ensure that the conveying device 2 is pushed to the original position, so that a safety accident is avoided when the conveying device 2 is started.
Specifically, the fixing frame 1 further includes a bottom plate 12, the bottom plate 12 is used for supporting at least two conveying devices 2, a first magnetic member 121 is disposed at one end of the bottom plate 12 corresponding to the supply channel 21, a second magnetic member 203 and a second sensor 202 are disposed on the guide plate 20, after the conveying devices 2 move to a predetermined position along the mounting plate 11, the first magnetic member 121 and the second magnetic member 203 are adsorbed together, and the second sensor 202 is triggered to send a third signal to the controller.
Alternatively, the first magnetic member 121 is a magnet, the second magnetic member 203 is a metal member having magnetic attraction property, such as an iron plate, a nickel plate or an iron-nickel alloy plate, and the outer surface is coated with an anti-corrosion coating. Alternatively, the second magnetic member 203 may be an electrolytic lead-zinc-plated sheet, i.e., a zinc-plated layer on the surface of a cold-rolled sheet. Optionally, the second sensor 202 is a micro switch, and the micro switch is a switch triggered by physical and mechanical, so that the micro switch is not interfered by the attribute of the triggering object, and the problem of detection misjudgment caused by the traditional photoelectric sensor can be effectively solved. The second magnetic member 203 and the second sensor 202 are located in the same plane, and when the first magnetic member 121 and the second magnetic member 203 are attracted together, the conveying device 2 is illustrated to move to a predetermined position along the mounting plate 11, and at this time, the first magnetic member 121 can just touch the second sensor 202, so that the second sensor 202 is triggered to send a third signal to the controller. The third signal indicates that the conveyor 2 has moved to a predetermined position along the mounting plate 11 and can be switched to the operating mode at any time.
In addition, as shown in fig. 3, magnetic beads O are preset in the reaction container C for subsequent mixing of the sample with the functional modules such as reaction reagent and magnetic bead detection. In order to prevent the first magnetic member 121 from magnetizing the magnetic beads O in the reaction vessel C, affecting the magnetic bead detection result, the height difference between the first magnetic member 121 and the reaction vessel C needs to satisfy a preset distance. The predetermined distance is related to the magnitude of the magnetic force of the first magnetic member 121, depending on the specific application.
Due to machining errors of parts such as the mounting plate 11 or assembly errors of the parts with the guide rail 111 and the sliding block 112, the conveying device 2 may shift in the direction in which at least two conveying devices 2 are arranged side by side, so that the conveying devices 2 wear during operation, which is unfavorable for the conveying precision of the conveying devices 2 for supplying the reaction containers C.
To solve this problem, the end of the bottom plate 12 corresponding to the supply passage 21 is further provided with a fixing member 122, the fixing member 122 is provided with a positioning pin 123, the guide plate member 20 is correspondingly provided with a pin hole 204 which is engaged with the positioning pin 123, and the positioning pin 123 extends into the pin hole 204 after the conveying device 2 moves to a predetermined position along the mounting plate 11. By the engagement of the positioning pin 123 with the pin hole 204, the conveying device 2 can be positioned quickly. At the same time, the continuous magnetic attraction force generated between the first magnetic member 121 and the second magnetic member 203 can ensure that the conveying device 2 does not move in the side-by-side direction, and further improves the conveying precision of the conveying device 2 for supplying the reaction containers C.
Referring to fig. 5 to 7, each conveyor 2 includes a support plate 22, a turntable 23, a conveyor belt 24, and a wheel assembly 25.
The support plate 22 is movably coupled to the mounting plate 11, and a pair of guide plates 20 are fixedly coupled to the support plate 22. Specifically, the support plate 22 is connected to the slider 112 of the aforementioned moving device, so as to realize movable connection of the support plate 22 to the mounting plate 11. The support plate 22 further includes a bent portion 223 parallel to the bottom plate 12, and a pair of guide plates 20 are disposed at the bent portion 223 to form the supply passage 21.
The turntable 23 is rotatably connected with the support plate 22, and the turntable 23 includes a rotating shaft 231 and a pair of disk bodies 232 coaxially connected with the rotating shaft 231 and arranged at intervals.
One end of the conveyor belt 24 is wound on the rotating shaft 231 between the pair of disc bodies 232, the conveyor belt 24 is provided with a plurality of reaction containers C which are sequentially arranged along the length direction of the conveyor belt 24, and the reaction containers C are positioned on one side of the conveyor belt 24 away from the rotating shaft 231.
The rotating wheel assembly 25 is connected to the support plate 22, the rotating wheel assembly 25 is disposed between the turntable 23 and the guide plate 20, and the other end of the conveyor belt 24 is wound around the rotating wheel assembly 25 for guiding the reaction containers C on the conveyor belt 24 to the supply passage 21.
Further, the wheel assembly 25 includes a drive motor 251, a drive wheel 252, a first guide wheel 253, and a second guide wheel 254.
The driving motor 251 is electrically connected to the controller and to the support plate 22. The driving wheel 252 is coaxially connected with the output shaft of the driving motor 251, an annular groove 252a is arranged on the driving wheel 252, and the other end of the conveyor belt 24 is wound on the annular groove 252 a. Specifically, the driving motor 251 and the driving wheel 252 are respectively disposed on two sides of the supporting plate 22, so as to drive the driving wheel 252 to drive the conveyor belt 24 to rotate.
The first guide wheel 253 and the second guide wheel 254 are respectively positioned between the turntable 23 and the driving pulley 252 and are in frictional contact with the conveyor belt 24, the first guide wheel 253 is positioned close to the turntable 23 for guiding the conveyor belt 24 into the supply channel 21, and the second guide wheel 254 is positioned on one side of the first guide wheel 253 away from the turntable 23 and above the supply channel 21 for separating the reaction containers C from the conveyor belt 24.
As shown in fig. 5, the driving motor 251 drives the driving wheel 252 to rotate in a counterclockwise direction, and drives the conveyor belt 24 to move in the arrow direction in the drawing, and the conveyor belt 24 wound by the rotating shaft 231 of the turntable 23 is wound onto the annular groove 252a of the driving wheel 252 under the guidance of the first guide wheel 253 and the second guide wheel 254, and simultaneously conveys the plurality of reaction containers C disposed on the conveyor belt 24 into the supply passage 21 under the second guide wheel 254.
Wherein the reaction vessel C is separated from the conveyor belt 24 as the conveyor belt 24 passes the second guide wheel 254, and thus falls into the supply passage 21 under the second guide wheel 254. The separation of the reaction vessel C from the conveyor belt 24 is related to the arrangement of the components of the rotor assembly 25 and the structure of the feed channel 21.
In one aspect, as shown in fig. 5, a first central line between the central axis of the first guide wheel 253 and the central axis of the second guide wheel 254 is L1, a second central line between the central axis of the second guide wheel 254 and the central axis of the driving wheel 252 is L2, and an included angle θ between the first central line L1 and the second central line is equal to or greater than 90 °.
Since the included angle θ between the first central line L1 and the second central line L2 is greater than or equal to 90 °, when the conveyor belt 24 is guided into the supply channel 21 by the first guide wheel 253 and is in frictional contact with the second guide wheel 254, the reaction container C shown at the far right in fig. 5 has a tendency to separate from the conveyor belt 24 moving upward under the action of its own gravity.
On the other hand, as shown in fig. 3 and 7, the reaction vessel C has oppositely disposed ears E, and the ears E are connected to the conveyor belt 24. Specifically, the reaction vessel C further includes a vessel body C1, the oppositely disposed ears E are connected with the vessel body C1, the ears E are provided with fixing posts C2 thereon, and the fixing posts C2 pass through the through holes on the conveyor belt 24, thereby connecting the ears E of the reaction vessel C with the conveyor belt 24. Each guide plate member 20 is provided with an inwardly recessed groove 205 on a side facing the supply passage 21, and a width dimension d1 between the oppositely disposed ears E is larger than a width dimension d2 of the conveyor belt 24 and smaller than a distance d3 between the pair of grooves 205.
When the conveyor belt 24 is guided into the supply channel 21, it moves toward the driving wheel 252 under the guiding action of the second guiding wheel 254, so as to drive the reaction container C to move upward, while the ears E of the reaction container C are blocked by the grooves 205 provided in the pair of guiding plates 20, and the conveyor belt 24 continues to move upward toward the driving wheel 252 through the grooves 205, while the reaction container C moves downward under the action of its own gravity, so that the conveyor belt 24 is separated from the reaction container C, and the reaction container C falls into the supply channel 21.
Referring to fig. 4 and 7-9, the reactor supply apparatus further includes a cover assembly 3, the cover assembly 3 includes a cover plate 31 and an extension portion 32, the cover plate 31 covers the supply channel 21 between the second guide wheel 254 and the discharging position P2, the extension portion 32 is disposed on a side of the cover plate 31 facing the supply channel 21, and the extension portion 32 is telescopically inserted into the supply channel 21 under the second guide wheel 254.
As shown in fig. 8 and 9, the cap assembly 3 further includes a toggle 33 and a hinge 34, and the cover plate 31 is pivotally connected to the guide plate 20 by the hinge 34 to open or close the supply passage 21. The toggle member 33 is disposed on a side of the cover plate 31 facing away from the supply passage 21 and is connected to the protruding portion 32. One end of the extension 32 is telescopically inserted between the second guide wheel 254 and the reaction vessel C in the supply passage 21, the other end is provided with a cylinder, a spring (not shown in the drawing) is sleeved outside the cylinder, and the cover plate 31 is correspondingly provided with a hole matched with the cylinder and the spring, so that the extension 32 can telescopically move relative to the cover plate 31. When the toggle member 33 is moved in the arrow direction in fig. 8, the protruding portion 32 can be inserted into the supply passage 21 under the second guide wheel 254. When the toggle member 33 is moved in a direction opposite to the arrow direction in fig. 8, the protruding portion 32 is withdrawn from the supply passage 21 under the second guide wheel 254, so that the cover plate 31 can be turned around the hinge 34 to open the supply passage 21.
As shown in fig. 7, the reaction container C is pre-provided with magnetic beads O therein, and when the conveyor belt 24 is separated from the reaction container C, the opening H of the reaction container C is opened, the reaction container C moves downward to fall into the supply passage 21, and the magnetic beads O tend to escape toward the opening H of the reaction container C due to inertia. By moving the toggle member 33 to the left, the projecting portion 32 can be inserted into the supply passage 21 below the second guide wheel 254 and covered with the opening H of the reaction container C just separated from the conveyor belt 24, so that the magnetic beads O can be prevented from escaping from the opening H. In addition, the cover plate 31 covers the supply channel 21 between the second guide wheel 254 and the discharging position P2, so as to prevent impurities such as dust from falling into the reaction container C, thereby avoiding affecting the cleanliness of the subsequent sample and the accuracy of the sample analysis result.
When most of the conveyor belt 24 wound around the rotating shaft 231 of the turntable 23 is wound around the annular groove 252a of the driving pulley 252 and the conveyor belt 24 is in a tensioned state, the conveyor belt 24 cannot drive the reaction containers C to move toward the feeding channel 21, the controller recognizes that the operation state of the conveying device 2 is abnormal, and controls the driving motor 251 to stop rotating, and at this time, a small amount of reaction containers C fall into the feeding channel 21 and cannot move to the discharging position P2. The conveying device 2 is moved out of the fixing frame 1, the toggle piece 33 is moved to the right, then the cover plate 31 is turned around the pivot of the hinge 34, so that a small amount of reaction containers C falling into the supply channel 21 can be manually taken out, and the counting of the reaction containers C arranged on the new conveying belt 24 is prevented from being influenced.
If the counting of the reaction containers C does not need to be considered, the controller does not receive the first signal or the second signal sent by the first sensor 201 of the conveying device 2 currently in the working mode within a predetermined time to determine the running state of the current conveying device 2, a small number of reaction containers C may also be manually moved to a suitable position, for example, the reaction container C in the front of the queue is moved to the discharging position P2, and the remaining reaction containers C are sequentially arranged, so that the movement of the new conveyor belt 24 is not affected, and the waste of the reaction containers C is avoided. Then, the cover plate 31 is turned around the hinge 34, the cover plate 31 is covered on the supply channel 21, the toggle piece 33 is moved to the left, the new conveyor belt 24 is reloaded between the rotating shaft 231 of the rotating disc 23 and the rotating wheel assembly 25, and the conveying device 2 is moved to the original position of the fixing frame 1 to serve as a standby conveying device.
Referring to fig. 6 again, a supporting plate 22 of the conveying device 2 is provided with a boss 221 and a lock pin 222 rotatably connected with the boss 221 corresponding to a rotating shaft 231 of the turntable 23, the rotating shaft 231 is sleeved on the outer periphery side of the boss 221 and is pressed on one of the discs 232 through the lock pin 222, and an elastic member 26 is arranged between the other disc 232 and the supporting plate 22.
Alternatively, the elastic member 26 is an O-ring rubber. Because the arm of force of the locking pin 222 pressing the disc 232 is short, the disc 232 is not easily pressed. The elastic piece 26 is arranged between the tray 232 and the support plate 22, so that friction force generated by extrusion between the tray 232 and the support plate 22 can be increased, and the anti-loosening purpose is achieved.
Referring to fig. 10, an embodiment of the present invention further provides a reaction vessel supply method of the reaction vessel supply apparatus as described above, including:
Step S1, acquiring the running state information of the conveying device 2 in the current working mode for supplying the reaction vessel C;
Step S2, when the running state information is abnormal, sending a stop signal to the current conveying device 2;
step S3, starting the other conveying device 2 of the at least two conveying devices 2 to continue to supply the reaction vessel C.
As described above, when the controller determines that the current operation state of the conveyor device 2 is abnormal, there is a possibility that the remaining amount of the reaction container C is insufficient, or that the current conveyor device 2 is out of order, and the conveyor device 2 needs to be pulled out of the holder 1 along the moving device to perform maintenance, for example, the reaction container C is reloaded into the conveyor device 2, the problem of the failure of the conveyor device 2 is eliminated, and the conveyor device 2 is pushed to the original position of the holder 1 after the maintenance is completed. The maintenance process does not affect the normal operation of other conveying devices 2, so that the reaction container C can be continuously supplied, the time for stopping the machine to treat abnormal problems is reduced, and the working efficiency of the whole machine is improved.
While the invention has been described with reference to a preferred embodiment, various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, the technical features mentioned in the respective embodiments may be combined in any manner as long as there is no structural conflict. The present invention is not limited to the specific embodiments disclosed herein, but encompasses all technical solutions falling within the scope of the claims.

Claims (13)

1. A reaction vessel supply apparatus, comprising:
the fixing frame comprises at least two mounting plates;
the at least two conveying devices are respectively and movably connected with the at least two mounting plates in one-to-one correspondence, so that the conveying devices can be pulled out from the fixing frame;
Each of the conveying devices includes:
The rotary table comprises a rotary shaft and a pair of disc bodies which are coaxially connected with the rotary shaft and are arranged at intervals;
One end of the conveyor belt is wound on the rotating shaft between the pair of disc bodies, a plurality of reaction containers which are sequentially arranged are arranged on the conveyor belt along the length direction of the conveyor belt, and magnetic beads are preset in the reaction containers;
A pair of guide plates disposed opposite to each other, a supply passage being formed between the pair of guide plates, through which the conveying device supplies a plurality of reaction containers;
a runner assembly cooperating with the feed channel for separating the conveyor belt from the reaction vessel and transporting the reaction vessel along the feed channel;
and when the operation state is abnormal, closing the current conveying device, and starting the other conveying device of the at least two conveying devices to continue to supply the reaction container.
2. The reactor vessel feeding apparatus according to claim 1, wherein the feeding passage of each of the conveying apparatuses has a feeding position and a discharging position in a longitudinal direction thereof, and the guide plate member is provided with a first sensor corresponding to the discharging position for sending a first signal to the controller when the reactor vessel reaches the discharging position and a second signal to the controller when the reactor vessel is taken out.
3. The reaction vessel supply apparatus according to claim 2, wherein the controller is further configured to count the number of times the first signal is transmitted by the first sensor of the conveying apparatus currently in the operation mode, and determine that the current operation state of the conveying apparatus is abnormal when the number of times the first signal is equal to a supply threshold value of the reaction vessel.
4. The reaction vessel supply apparatus according to claim 2, wherein the controller is further configured to determine that the current operation state of the conveying apparatus is abnormal when the first signal or the second signal transmitted from the first sensor of the conveying apparatus currently in the operation mode is not received within a predetermined time.
5. The reactor vessel feeding apparatus according to claim 1, wherein the holder further comprises a bottom plate for supporting the at least two conveying means, a first magnetic member is provided at one end of the bottom plate corresponding to the feeding passage, a second magnetic member and a second sensor are provided on the guide plate, and the first magnetic member and the second magnetic member are attracted together after the conveying means moves to a predetermined position along the mounting plate, and the second sensor is triggered to send a third signal to the controller.
6. The reactor vessel feeding apparatus according to claim 5, wherein one end of the bottom plate corresponding to the feeding passage is further provided with a fixing member, the fixing member is provided with a positioning pin, the guide plate member is correspondingly provided with a pin hole which is engaged with the positioning pin, and the positioning pin extends into the pin hole after the conveyor moves to the predetermined position along the mounting plate.
7. The reaction vessel supply apparatus according to claim 1, wherein each of the conveying means comprises:
The support plate is movably connected with the mounting plate, and the pair of guide plates are fixedly connected with the support plate;
The turntable is rotatably connected with the supporting plate;
the reaction container is positioned at one side of the conveyor belt away from the rotating shaft;
the rotating wheel assembly is connected with the supporting plate, the rotating wheel assembly is arranged between the rotating disc and the guide plate, and the other end of the conveying belt is wound on the rotating wheel assembly and used for guiding the reaction container on the conveying belt into the supply channel.
8. The reactor vessel feeding apparatus as recited in claim 7, wherein the runner assembly comprises:
the driving motor is electrically connected with the controller and is connected with the supporting plate;
the driving rotating wheel is coaxially connected with an output shaft of the driving motor, an annular groove is formed in the driving rotating wheel, and the other end of the conveying belt is wound on the annular groove;
The first guide wheel and the second guide wheel are respectively positioned between the rotary table and the driving rotary wheel and are in friction contact with the conveying belt, the first guide wheel is close to the rotary table and is used for guiding the conveying belt into the supply channel, and the second guide wheel is positioned on one side, away from the rotary table, of the first guide wheel and is positioned above the supply channel and is used for separating the reaction container from the conveying belt.
9. The reactor supply apparatus according to claim 8, wherein a first center line between the center axis of the first guide wheel and the center axis of the second guide wheel is L1, a second center line between the center axis of the second guide wheel and the center axis of the driving wheel is L2, and an angle θ between the first center line L1 and the second center line is equal to or larger than 90 °.
10. The reactor vessel feeding apparatus according to claim 7, wherein the reactor vessel has oppositely disposed ears connected to the conveyor belt, each of the guide plates is provided with an inwardly recessed groove on a side facing the feed passage, and a width dimension d1 between the oppositely disposed ears is larger than a width dimension d2 of the conveyor belt and smaller than a distance d3 between a pair of the grooves.
11. The reactor vessel feeding apparatus according to claim 8, further comprising a cover assembly including a cover plate covering the feeding passage between the second guide wheel and the discharge position, and a protruding portion provided on a side of the cover plate facing the feeding passage, and the protruding portion is telescopically inserted into the feeding passage below the second guide wheel.
12. The reactor supply apparatus according to claim 7, wherein a boss and a lock pin rotatably connected to the boss are provided in the support plate in correspondence with a rotation shaft of the turntable, the rotation shaft is fitted around an outer peripheral side of the boss and is press-fitted to one of the tray bodies through the lock pin, and an elastic member is provided between the other tray body and the support plate.
13. A reaction vessel supply method of the reaction vessel supply apparatus according to any one of claims 1 to 12, comprising:
acquiring the running state information of the conveying device in the current working mode for supplying to the reaction vessel;
when the running state information is abnormal, sending a stop signal to the current conveying device;
Activating another one of the at least two conveying means to continue feeding the reaction vessel.
CN202011001581.2A 2020-09-22 2020-09-22 Reaction vessel supply device and reaction vessel supply method Active CN112129961B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202011001581.2A CN112129961B (en) 2020-09-22 2020-09-22 Reaction vessel supply device and reaction vessel supply method
PCT/CN2021/119715 WO2022063141A1 (en) 2020-09-22 2021-09-22 Reaction vessel supply apparatus and reaction vessel supply method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011001581.2A CN112129961B (en) 2020-09-22 2020-09-22 Reaction vessel supply device and reaction vessel supply method

Publications (2)

Publication Number Publication Date
CN112129961A CN112129961A (en) 2020-12-25
CN112129961B true CN112129961B (en) 2025-12-30

Family

ID=73842139

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011001581.2A Active CN112129961B (en) 2020-09-22 2020-09-22 Reaction vessel supply device and reaction vessel supply method

Country Status (2)

Country Link
CN (1) CN112129961B (en)
WO (1) WO2022063141A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112129961B (en) * 2020-09-22 2025-12-30 迈克医疗电子有限公司 Reaction vessel supply device and reaction vessel supply method
CN114994345A (en) * 2022-06-16 2022-09-02 迈克医疗电子有限公司 Reaction vessel conveying device, reaction vessel conveying system and control method thereof
CN116087546B (en) * 2022-12-12 2023-11-24 南京诺唯赞医疗科技有限公司 Automatic loading device for reaction cup and sample analyzer
CN116660558A (en) * 2023-04-04 2023-08-29 迈克医疗电子有限公司 Reaction container detection method, detection device and sample analysis equipment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102236026A (en) * 2010-03-30 2011-11-09 希森美康株式会社 Sample rack transport system and sample rack transport method
CN103901222A (en) * 2012-12-27 2014-07-02 深圳雷杜生命科学股份有限公司 Reaction vessel transmission mechanism
CN107247134A (en) * 2017-06-28 2017-10-13 苏州长光华医生物医学工程有限公司 A kind of reaction cup anti-sticking cup conveying device
CN108238433A (en) * 2018-01-03 2018-07-03 迪瑞医疗科技股份有限公司 A kind of container continuous feeding device and method
CN109521211A (en) * 2017-09-20 2019-03-26 深圳迈瑞生物医疗电子股份有限公司 Reaction container automatic loading device and method

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595707A (en) * 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
ES2259277T3 (en) * 1993-09-24 2006-10-01 Abbott Laboratories METHOD OF OPERATING AN AUTOMATIC ANALYTICAL SYSTEM OF CONTINUOUS RANDOM ACCESS ABLE TO SIMULTANEOUSLY MULTIPLE TESTS IN A PLURALITY OF LIQUID SAMPLES.
US5908599A (en) * 1996-07-30 1999-06-01 Bayer Corporation Heated reaction chamber in a unified fluid circuit of a hematology diagnostic instrument
JP4804766B2 (en) * 2005-02-10 2011-11-02 日鉄鉱業株式会社 Container supply method and container supply apparatus
DE102012206295A1 (en) * 2012-04-17 2013-10-17 Krones Ag Filling plant for containers and method for operating the filling plant
FR3047082B1 (en) * 2016-01-25 2018-02-16 Arteion SUPPLY CONVEYING SYSTEM FOR CONTAINERS OF BIOLOGICAL LIQUID SAMPLES, AND AUTOMATIC ANALYSIS SYSTEM COMPRISING SUCH A CONVEYING SYSTEM
CN106768984B (en) * 2017-02-17 2019-02-22 安图实验仪器(郑州)有限公司 The test method of bulk type reaction cup automatic sequencing device
CN207516388U (en) * 2017-11-30 2018-06-19 深圳优迪生物技术有限公司 A kind of multistation specific protein analytical equipment
CN207698724U (en) * 2017-12-26 2018-08-07 河北省烟草公司唐山市公司 Special-shaped cigarette sorting line
KR101973503B1 (en) * 2018-07-10 2019-04-29 (주)에스티아이 Akutomatic transfer apparatus of chemical container and the method thereof
CN209939942U (en) * 2019-05-16 2020-01-14 上海易研机械设备有限公司 Full-automatic feeding and distributing system for high-viscosity materials
CN110422364B (en) * 2019-09-16 2024-07-02 山东大窑饮品有限公司 Automatic packaging equipment and packaging method for bottle-shaped containers
CN209870804U (en) * 2019-11-28 2019-12-31 山东交通职业学院 Transition conveying device
CN112129961B (en) * 2020-09-22 2025-12-30 迈克医疗电子有限公司 Reaction vessel supply device and reaction vessel supply method
CN213337677U (en) * 2020-09-22 2021-06-01 迈克医疗电子有限公司 Reactor vessel supply device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102236026A (en) * 2010-03-30 2011-11-09 希森美康株式会社 Sample rack transport system and sample rack transport method
CN103901222A (en) * 2012-12-27 2014-07-02 深圳雷杜生命科学股份有限公司 Reaction vessel transmission mechanism
CN107247134A (en) * 2017-06-28 2017-10-13 苏州长光华医生物医学工程有限公司 A kind of reaction cup anti-sticking cup conveying device
CN109521211A (en) * 2017-09-20 2019-03-26 深圳迈瑞生物医疗电子股份有限公司 Reaction container automatic loading device and method
CN108238433A (en) * 2018-01-03 2018-07-03 迪瑞医疗科技股份有限公司 A kind of container continuous feeding device and method

Also Published As

Publication number Publication date
WO2022063141A1 (en) 2022-03-31
CN112129961A (en) 2020-12-25

Similar Documents

Publication Publication Date Title
CN112129961B (en) Reaction vessel supply device and reaction vessel supply method
CN105593687B (en) Automatic analysing apparatus
US9835639B2 (en) Gripping mechanism
EP3683582B1 (en) Automated analyzing device
WO2001069263A1 (en) Automatic analyzer and part feeding device used for the analyzer
EP2883667B1 (en) Device and method for gripping vessels
CN109677872B (en) Automatic sample tube feeding device
CN213337677U (en) Reactor vessel supply device
CN109813883B (en) Cup arranging system for immunity analyzer
CN108196077B (en) Reagent container carrier and carrier system
US8074235B2 (en) Control method for a media transportation mechanism, and a media processing device
JP7165466B2 (en) automatic analyzer
CN216004404U (en) Loading attachment and battery production facility
CN212598483U (en) Button combination machine
CN217605879U (en) Incubation unit cup discarding mechanism and sample analyzer
CN217296316U (en) Reaction cup detects grabbing device and chemiluminescence analysis appearance
CN120028560A (en) Sample analysis device
CN216979105U (en) Reaction cup automatic loading device and in-vitro diagnosis analyzer
CN116413463A (en) Cup discarding mechanism, sample analyzer and cup discarding method of incubation unit
CN221661581U (en) Non-stop waste treatment device and analyzer using same
JP5452526B2 (en) Automatic analyzer
EP4685493A1 (en) Piercing mechanism and automatic analysis device including same
CN114994345A (en) Reaction vessel conveying device, reaction vessel conveying system and control method thereof
CN221342560U (en) Motor front cover torsion spring feed divider
KR100978400B1 (en) Bill ejector and bill ejector control method

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant