CN112773765A - 治疗普拉德-威利综合征的方法 - Google Patents

治疗普拉德-威利综合征的方法 Download PDF

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Publication number
CN112773765A
CN112773765A CN202110278199.4A CN202110278199A CN112773765A CN 112773765 A CN112773765 A CN 112773765A CN 202110278199 A CN202110278199 A CN 202110278199A CN 112773765 A CN112773765 A CN 112773765A
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CN
China
Prior art keywords
carbetocin
day
substituted
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110278199.4A
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English (en)
Chinese (zh)
Inventor
帕斯卡尔·丹格拉斯
迈克尔·雷迪
保罗·考纳尔
苏达考迪·阿拉加萨米
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Firelink
Ferring BV
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Firelink
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Publication of CN112773765A publication Critical patent/CN112773765A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202110278199.4A 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法 Pending CN112773765A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462052957P 2014-09-19 2014-09-19
US62/052,957 2014-09-19
CN201580049147.2A CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Related Parent Applications (1)

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CN201580049147.2A Division CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Publications (1)

Publication Number Publication Date
CN112773765A true CN112773765A (zh) 2021-05-11

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110278199.4A Pending CN112773765A (zh) 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法
CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Family Applications After (1)

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Country Status (16)

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US (3) US10441627B2 (2)
EP (2) EP3193907B1 (2)
JP (3) JP6599447B2 (2)
CN (2) CN112773765A (2)
CA (1) CA2957224A1 (2)
DK (1) DK3666258T3 (2)
ES (2) ES2970059T3 (2)
FI (1) FI3666258T3 (2)
HR (1) HRP20240166T1 (2)
HU (1) HUE065829T2 (2)
LT (1) LT3666258T (2)
PL (1) PL3666258T3 (2)
PT (1) PT3666258T (2)
RS (1) RS65144B1 (2)
SI (1) SI3666258T1 (2)
WO (1) WO2016044131A1 (2)

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ES2970059T3 (es) 2014-09-19 2024-05-24 Ferring Bv Método de tratamiento del síndrome de Prader-Willi
US20190135859A1 (en) 2017-08-11 2019-05-09 Ferring B.V. Method of manufacturing a pharmaceutical composition
BR112020001832A2 (pt) 2017-08-11 2020-07-28 Ferring B.V. método de produção de uma composição farmacêuti-ca
US10736894B2 (en) 2018-02-15 2020-08-11 Ovid Therapeutics Inc. Methods of treating developmental syndromes with PDE10A inhibitors
EP3852724A4 (en) 2018-09-20 2022-07-06 Levo Therapeutics, Inc. CARBETOCIN DRUG PRODUCT AND PROCESS FOR ITS MANUFACTURE
TW202031283A (zh) * 2018-09-20 2020-09-01 馬克 C 曼寧 穩定卡貝縮宮素鼻內製劑
CA3205469A1 (en) * 2020-12-18 2022-06-23 The General Hospital Corporation Probiotics compositions and method of using the same to enhance growth and social function in children
ES3010259T3 (en) 2021-03-26 2025-04-01 Ot4B Treatment of dysphagia

Citations (3)

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CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

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US7544662B2 (en) 1993-06-17 2009-06-09 Carle Development Foundation Polypeptides useful for appetite suppression
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
US6894026B1 (en) * 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
US9023793B2 (en) 2006-09-29 2015-05-05 Retrophin, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
CA2689476C (en) * 2007-06-07 2014-08-05 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
EP2187907A2 (en) 2007-09-11 2010-05-26 Mondobiotech Laboratories AG Use of tyr-w-mif-1 and urocortin 2 as therapeutic agents
WO2009033820A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
KR20100057642A (ko) 2007-09-11 2010-05-31 몬도바이오테크 래보래토리즈 아게 치료제로서의 cnp-22 단독 또는 피살라에민과 배합된 이의 용도
US20100184708A1 (en) 2007-09-11 2010-07-22 Dorian Bevec Use of gly-pro-glu-oh (gpe) as a therapeutic agent
EP2260053B1 (en) * 2008-03-31 2014-05-14 Ferring BV Oxytocin analogues
US8865746B2 (en) 2008-07-18 2014-10-21 Zafgen, Inc. Methods of treating an overweight or obese subject
US20120108510A1 (en) 2010-05-20 2012-05-03 Emory University Methods of improving behavioral therapies
EP2575853B1 (en) 2010-05-25 2016-08-24 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient
WO2012149472A2 (en) 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
EP2935312B1 (en) 2012-12-21 2018-08-08 F.Hoffmann-La Roche Ag Peptides as oxytocin agonists
AU2015270723A1 (en) 2014-06-03 2016-11-17 F. Hoffmann-La Roche Ag Peptides as oxytocin agonists
CR20160562A (es) 2014-06-06 2017-01-06 Hoffmann La Roche Péptidos como agonistas de la oxitocina
HRP20181916T1 (hr) 2014-08-07 2019-01-11 F. Hoffmann - La Roche Ag Postupci pripreme oksitocinskih analoga
ES2970059T3 (es) * 2014-09-19 2024-05-24 Ferring Bv Método de tratamiento del síndrome de Prader-Willi

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

Also Published As

Publication number Publication date
RS65144B1 (sr) 2024-02-29
DK3666258T3 (da) 2024-02-05
WO2016044131A1 (en) 2016-03-24
CA2957224A1 (en) 2016-03-24
US10441627B2 (en) 2019-10-15
US20200129584A1 (en) 2020-04-30
JP6921154B2 (ja) 2021-08-18
JP2017532316A (ja) 2017-11-02
SI3666258T1 (sl) 2024-04-30
JP6599447B2 (ja) 2019-10-30
US20170326200A1 (en) 2017-11-16
HUE065829T2 (hu) 2024-06-28
ES2775425T3 (es) 2020-07-27
HRP20240166T1 (hr) 2024-04-26
US20240082344A1 (en) 2024-03-14
EP3193907A1 (en) 2017-07-26
JP2020019790A (ja) 2020-02-06
PT3666258T (pt) 2024-02-01
LT3666258T (lt) 2024-01-10
FI3666258T3 (fi) 2024-02-09
JP2021098745A (ja) 2021-07-01
EP3666258B1 (en) 2023-11-15
EP3666258A1 (en) 2020-06-17
ES2970059T3 (es) 2024-05-24
CN106714819A (zh) 2017-05-24
EP3193907B1 (en) 2020-01-01
PL3666258T3 (pl) 2024-04-08

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