CR20180427A - Composición anestésica tópica - Google Patents

Composición anestésica tópica

Info

Publication number
CR20180427A
CR20180427A CR20180427A CR20180427A CR20180427A CR 20180427 A CR20180427 A CR 20180427A CR 20180427 A CR20180427 A CR 20180427A CR 20180427 A CR20180427 A CR 20180427A CR 20180427 A CR20180427 A CR 20180427A
Authority
CR
Costa Rica
Prior art keywords
topical anesthetic
composition
anesthetic composition
pump
pharmaceutically acceptable
Prior art date
Application number
CR20180427A
Other languages
English (en)
Inventor
Garry Gwozdz
Original Assignee
Cetylite Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetylite Ind Inc filed Critical Cetylite Ind Inc
Publication of CR20180427A publication Critical patent/CR20180427A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/08—Implements for therapeutic treatment combined with anaesthetising implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00—Local anaesthesia; Hypothermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dentistry (AREA)
  • Emergency Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Se provee una composición anestésica tópica que comprende benzocaína, sal farmacéuticamente aceptable de la misma, amida de la misma y/o éster de la misma; tetracaína y/o sal farmacéuticamente aceptable de la misma; etanol; polietilenglicol; propilenglicol; agua; y alcohol bencílico. También se proporciona un método para dispensar la composición anestésica tópica anterior a un sitio deseado, tal como pulverizando el anestésico tópico desde un dispositivo de pulverización de dosis medida accionado por una bomba. La composición anestésica tópica también puede administrarse por vía subgingival con una jeringa y una punta aplicadora. Un producto que comprende la composición de pulverización anestésica tópica anterior contenida en un dispositivo de pulverización de dosis medida accionado por una bomba
CR20180427A 2016-03-04 2017-03-02 Composición anestésica tópica CR20180427A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/061,281 US10039830B2 (en) 2016-03-04 2016-03-04 Topical anesthetic composition
PCT/US2017/020411 WO2017151893A1 (en) 2016-03-04 2017-03-02 Topical annesthetic composition

Publications (1)

Publication Number Publication Date
CR20180427A true CR20180427A (es) 2019-01-22

Family

ID=59722459

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20180427A CR20180427A (es) 2016-03-04 2017-03-02 Composición anestésica tópica

Country Status (14)

Country Link
US (1) US10039830B2 (es)
EP (1) EP3423050A4 (es)
JP (1) JP6708759B2 (es)
KR (1) KR101987342B1 (es)
CN (1) CN109219435A (es)
AU (1) AU2017227830A1 (es)
BR (1) BR112018067710A2 (es)
CA (1) CA3016309C (es)
CO (1) CO2018009584A2 (es)
CR (1) CR20180427A (es)
IL (1) IL261571B (es)
MX (1) MX366381B (es)
RU (1) RU2018131855A (es)
WO (1) WO2017151893A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109157721B (zh) * 2018-10-12 2022-03-18 王亚伟 一种麻醉科用部位麻醉自动准确定量喷雾装置

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832460A (en) * 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
US4052513A (en) 1974-12-13 1977-10-04 Plough, Inc. Stable topical anesthetic compositions
SE7713618L (sv) 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
US4344965A (en) 1978-10-13 1982-08-17 Raymond Stone Anesthetic compositions containing benzocaine
US4600575A (en) 1979-03-08 1986-07-15 American Home Products Corporation Aerosol anesthetic compositions
US5446063A (en) 1986-10-30 1995-08-29 American Home Products Corporation Anesthetic compositions
US5002974A (en) 1988-04-04 1991-03-26 Warner-Lambert Co. Anesthetic/skin moisturizing composition and method of preparing same
US5332576A (en) 1991-02-27 1994-07-26 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5618515A (en) 1992-08-19 1997-04-08 Blistex Inc. Aerosol spray composition for the treatment of dermal burns by cooling and anesthetizing the wound and valved container for dispensing same
US5760077A (en) 1994-01-14 1998-06-02 Shahinian, Jr.; Lee Topical ophthalmic analgesic preparations for sustained and extended corneal analgesia
US5585398A (en) 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
GB9422571D0 (en) 1994-11-09 1995-01-04 Whitehall Lab Ltd Haemorrihoidal compositions and method of use
US5563153A (en) 1995-02-22 1996-10-08 University Of Kansas Medical Center Sterile topical anesthetic gel
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
US5993836A (en) 1998-04-28 1999-11-30 Castillo; James G. Topical anesthetic formulation
US6114344A (en) 1998-07-16 2000-09-05 Aryx Therapeutics Long-acting local anesthetics
US6299902B1 (en) 1999-05-19 2001-10-09 The University Of Georgia Research Foundation, Inc. Enhanced transdermal anesthesia of local anesthetic agents
US6187294B1 (en) 1999-06-10 2001-02-13 Russell Anthony Penner Topical anesthetic prophylaxis composition and the method for use thereof in scaling and polishing teeth
WO2001028550A1 (en) 1999-10-15 2001-04-26 Mayo Foundation For Medical Education And Research Topical anesthetics useful for treating cancer, autoimmune diseases and ischemia
WO2001041550A2 (en) 1999-10-22 2001-06-14 Transdermatech, Inc. Topical anesthetic formulation
US6413499B1 (en) 2000-01-06 2002-07-02 Bryan M. Clay Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic
US6894078B2 (en) 2001-09-17 2005-05-17 James G. Castillo Alcohol based topical anesthetic formulation and method
BR0301968A (pt) 2003-05-22 2005-06-28 Cristalia Prod Quimicos Farm Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica
CN1241651C (zh) * 2003-05-22 2006-02-15 强生有限公司 止血抗菌产品及其制造方法
US20050014823A1 (en) 2003-07-17 2005-01-20 Soderlund Patrick L. Topical anesthetic composition and method of administration
WO2005027989A1 (en) 2003-09-17 2005-03-31 Shaw Sharon M Disinfectant, antibiotic and anesthetic containing device for injections and incisions
WO2005032521A2 (en) * 2003-10-02 2005-04-14 Collegium Pharmaceutical, Inc. Non-flammable topical anesthetic liquid aerosols
US20050137177A1 (en) 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic
US20070232695A1 (en) * 2004-01-28 2007-10-04 Collegium Pharmaceutical, Inc. Gelled Periodontal Anesthetic Preparation
US20060079558A1 (en) 2004-09-27 2006-04-13 Bridge Pharma. Inc. R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics
CA2656966C (en) 2005-03-15 2014-06-10 Animal Ethics Pty Ltd A topical analgesic composition
US20060222687A1 (en) 2005-04-01 2006-10-05 Carter Stephen G Topical anesthetic
US20070048338A1 (en) 2005-08-26 2007-03-01 Ladd Byron S Compositions and methods for surface treatment in medical and surgical procedures
US8623334B1 (en) 2005-09-29 2014-01-07 Alan J. Wickenhauser Topical anesthetic
US7695733B2 (en) 2006-02-17 2010-04-13 Zasler Nathan D Application of topical anesthetics for modulation of neurogenic tremor
EP1998742A2 (en) * 2006-03-08 2008-12-10 Nuviance, INC. Transdermal drug delivery compositions and topical compositions for application on the skin
US7754234B2 (en) 2006-07-12 2010-07-13 Jones Thomas L Composition and method of treating a sore throat
BRPI0807880A2 (pt) 2007-03-02 2014-06-17 Combe Internat Ltd Composição anestésica em spray.
US20080268050A1 (en) 2007-04-30 2008-10-30 Gerrish Donald L Sprayable topical skin barriers
BRPI0704542B8 (pt) * 2007-05-15 2021-05-25 Univ Estadual Campinas Unicamp composição farmacêutica, processo de obtenção da composição farmacêutica, uso de uma quantidade farmaceuticamente eficaz de anestésico e agente gelificante, produto e método de tratamento
JP5358574B2 (ja) 2007-08-17 2013-12-04 アルション セラピューティクス， インコーポレイテッド 高濃度の局所麻酔薬調合物
US8523569B2 (en) 2007-12-28 2013-09-03 Khashayar Kevin Neshat Controlled release local anesthetic for post dental surgery and method of use
WO2009092040A2 (en) 2008-01-17 2009-07-23 Gary Dean Bennett Topical pain formulation
US7883488B2 (en) 2008-06-16 2011-02-08 Shantha Totada R Transdermal local anesthetic patch with injection port
WO2010005400A1 (en) 2008-07-11 2010-01-14 Ix Biopharma Pte Ltd Opioid agonist compositions for pain management
US8231588B2 (en) 2008-08-01 2012-07-31 Tian Xia Methods for ameliorating pain and devices for delivering a medicament
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
US20110288123A1 (en) 2008-11-06 2011-11-24 Nuvo Research Inc. Formulations for the treatment of acute herpes zoster pain
NZ595376A (en) * 2009-04-03 2013-09-27 St Renatus Llc Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration
US20100305130A1 (en) 2009-06-01 2010-12-02 PHILLIPS Thomas Nasal spray device and method of use thereof
US20120004303A1 (en) 2010-06-30 2012-01-05 Church & Dwight Co., Inc. Method of dispensing a teething gel with a metered dose applicator
WO2013123249A2 (en) 2012-02-14 2013-08-22 Particle Sciences, Inc. Formulations and methods for treating ear conditions
US20140162958A1 (en) 2012-12-12 2014-06-12 Michael J. Robbins Copolymer-1 Composition and Methods of Use
WO2015021387A2 (en) 2013-08-09 2015-02-12 Britt George N Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations

Also Published As

Publication number Publication date
CA3016309C (en) 2019-11-19
WO2017151893A1 (en) 2017-09-08
JP2019508499A (ja) 2019-03-28
IL261571A (en) 2018-10-31
MX2018010645A (es) 2019-01-21
EP3423050A4 (en) 2019-10-09
US20170252445A1 (en) 2017-09-07
BR112018067710A2 (pt) 2019-01-08
CO2018009584A2 (es) 2018-10-22
CA3016309A1 (en) 2017-09-08
AU2017227830A1 (en) 2018-09-27
JP6708759B2 (ja) 2020-06-10
KR101987342B1 (ko) 2019-06-10
MX366381B (es) 2019-07-05
KR20180114957A (ko) 2018-10-19
US10039830B2 (en) 2018-08-07
CN109219435A (zh) 2019-01-15
IL261571B (en) 2019-01-31
RU2018131855A (ru) 2020-04-06
EP3423050A1 (en) 2019-01-09

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