CS17884A2 - Method of o-(2,6-dichloroanilino)phenylacetic acid's new resinate production - Google Patents

Method of o-(2,6-dichloroanilino)phenylacetic acid's new resinate production

Info

Publication number
CS17884A2
CS17884A2 CS84178A CS17884A CS17884A2 CS 17884 A2 CS17884 A2 CS 17884A2 CS 84178 A CS84178 A CS 84178A CS 17884 A CS17884 A CS 17884A CS 17884 A2 CS17884 A2 CS 17884A2
Authority
CS
Czechoslovakia
Prior art keywords
dichloroanilino
resinate
new
production
phenylacetic acid
Prior art date
Application number
CS84178A
Other languages
English (en)
Other versions
CS269954B2 (en
Inventor
Satish Chandra Dr Khanna
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CS17884A2 publication Critical patent/CS17884A2/cs
Publication of CS269954B2 publication Critical patent/CS269954B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS84178A 1983-01-12 1984-01-09 Method of o-(2,6-dichloroanilino)phenylacetic acid's new resinate production CS269954B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH14783A CH655507B (cs) 1983-01-12 1983-01-12

Publications (2)

Publication Number Publication Date
CS17884A2 true CS17884A2 (en) 1989-10-13
CS269954B2 CS269954B2 (en) 1990-05-14

Family

ID=4180317

Family Applications (1)

Application Number Title Priority Date Filing Date
CS84178A CS269954B2 (en) 1983-01-12 1984-01-09 Method of o-(2,6-dichloroanilino)phenylacetic acid's new resinate production

Country Status (41)

Country Link
US (1) US4510128A (cs)
EP (1) EP0122219B1 (cs)
JP (1) JPS59134759A (cs)
KR (1) KR900006747B1 (cs)
AR (1) AR240310A1 (cs)
AT (2) AT391467B (cs)
AU (1) AU570230B2 (cs)
BE (1) BE898649A (cs)
CA (1) CA1218077A (cs)
CH (1) CH655507B (cs)
CS (1) CS269954B2 (cs)
DD (1) DD218373A5 (cs)
DE (2) DE3474152D1 (cs)
DK (1) DK166683B1 (cs)
DZ (1) DZ593A1 (cs)
EG (1) EG16562A (cs)
ES (1) ES8504849A1 (cs)
FI (1) FI82682C (cs)
FR (1) FR2542735B1 (cs)
GB (1) GB2134529B (cs)
GR (1) GR79793B (cs)
HK (1) HK90390A (cs)
HU (1) HU190750B (cs)
IE (1) IE56545B1 (cs)
IL (1) IL70660A (cs)
IT (1) IT1177501B (cs)
LU (1) LU85171A1 (cs)
MA (1) MA20000A1 (cs)
MC (1) MC1564A1 (cs)
MT (1) MTP943B (cs)
NL (1) NL8400098A (cs)
NO (1) NO162862C (cs)
NZ (1) NZ206815A (cs)
OA (1) OA07628A (cs)
PH (1) PH21795A (cs)
PL (1) PL142737B1 (cs)
PT (1) PT77932B (cs)
RO (1) RO88481A (cs)
SE (1) SE457959B (cs)
ZA (1) ZA84212B (cs)
ZW (1) ZW484A1 (cs)

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CH664085A5 (de) * 1985-02-08 1988-02-15 Ciba Geigy Ag Pharmazeutische praeparate mit analgetischer wirksamkeit, sowie deren herstellung.
ES8604955A1 (es) * 1985-11-08 1986-03-16 Covex Sa Procedimiento para la preparacion de resinatos de la (-) eburnamenina-14-(15h)-ona
GB8730010D0 (en) * 1987-12-23 1988-02-03 Smith Kline French Lab Compounds
AU608114B2 (en) * 1987-12-23 1991-03-21 Smith Kline & French Laboratories Limited Compounds
US5230885A (en) * 1987-12-23 1993-07-27 Smith Kline & French Laboratories Limited Polystyrene anion exchange polymer pharmaceutical composition
CH675537A5 (cs) * 1988-03-25 1990-10-15 Ciba Geigy Ag
SE509029C2 (sv) * 1988-08-16 1998-11-30 Ss Pharmaceutical Co Långtidsverkande diklofenak-natriumpreparat
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
ES2054089T3 (es) * 1988-11-10 1994-08-01 Ciba Geigy Ag Formulaciones orales liquidas.
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
GB8911719D0 (en) * 1989-05-22 1989-07-05 Smith Kline French Lab Compounds
GB8913700D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
GB8913699D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
US5079001A (en) * 1989-11-03 1992-01-07 Ciba-Geigy Corporation Liquid oral formulation of diclofenac
GB8928278D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
SE9004129D0 (sv) * 1990-12-21 1990-12-21 Pharmacia Lkb Biotech Anion exchanger
EP0592569A1 (en) * 1991-07-03 1994-04-20 Sano Corporation Composition and method for transdermal delivery of diclofenac
DE60232290D1 (de) * 2001-04-09 2009-06-25 Rohm & Haas Kontrollierte Auflösung von Wirkstoffen
US20020176842A1 (en) * 2001-04-09 2002-11-28 Lyn Hughes Extended release of active ingredients
US20030180249A1 (en) * 2002-03-18 2003-09-25 Khanna Satish Chandra Dosage forms for hygroscopic active ingredients
RU2221559C1 (ru) * 2002-11-15 2004-01-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Препарат диклофенак натрия длительного действия
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US20080095842A1 (en) * 2004-12-06 2008-04-24 Antarkar Amit K Rapidly Disintegrating Taste Masked Compositions and a Process for Its Preparations
ATE536867T1 (de) 2006-03-16 2011-12-15 Tris Pharma Inc Modifizierte freisetzungsformulierungen mit arznei-ion-austausch-harzkomplexen
US7799347B2 (en) * 2006-09-07 2010-09-21 Chondrex Inc. Endotoxin-adsorbent for the prevention and treatment of autoimmune diseases
ES2651948T3 (es) * 2008-10-02 2018-01-30 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Administración de un polímero adsorbente para el tratamiento de la inflamación sistémica
MX377251B (es) 2010-03-24 2025-03-07 Jazz Pharmaceuticals Inc Star Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.
AU2013302657B2 (en) 2012-08-15 2018-08-09 Tris Pharma, Inc. Methylphenidate extended release chewable tablet
US10398662B1 (en) 2015-02-18 2019-09-03 Jazz Pharma Ireland Limited GHB formulation and method for its manufacture
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12478604B1 (en) 2016-07-22 2025-11-25 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12186296B1 (en) 2016-07-22 2025-01-07 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US20180263936A1 (en) 2017-03-17 2018-09-20 Jazz Pharmaceuticals Ireland Limited Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US12458592B1 (en) 2017-09-24 2025-11-04 Tris Pharma, Inc. Extended release amphetamine tablets
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
BR112021006027A2 (pt) 2018-11-19 2021-06-29 Jazz Pharmaceuticals Ireland Limited formulações de fármaco resistente a álcool
US11400065B2 (en) 2019-03-01 2022-08-02 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
TW202139986A (zh) 2020-02-21 2021-11-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 治療原發性嗜睡症之方法
WO2022076824A1 (en) 2020-10-08 2022-04-14 Jazz Pharmaceuticals Ireland Limited Sodium oxybate to treat idiopathic hypersomnia
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
JP2026513019A (ja) 2023-02-03 2026-04-22 トリス・フアルマ・インコーポレーテツド １晩１回の低ナトリウムオキシベート組成物

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GB823000A (en) * 1957-10-03 1959-11-04 Clinical Products Ltd Resin-drug compounds
GB869149A (en) * 1958-09-16 1961-05-31 Clinical Products Ltd Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances
US3316282A (en) * 1965-02-08 1967-04-25 Squibb & Sons Inc Anion exchange resin complex of a cycloborate ester of a steroid
SE366296B (cs) * 1967-12-20 1974-04-22 Ciba Geigy Ag
CH519476A (de) * 1968-03-30 1972-02-29 Hoechst Ag Verfahren zur Herstellung von Salzen von Acylamino-alkylbenzolsulfonyl-harnstoffen mit Anionenaustauschern
US3926864A (en) * 1971-06-21 1975-12-16 Ionics Ion exchange membranes having a macroporous surface area
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FR2352547A1 (fr) * 1976-05-25 1977-12-23 Viridis Ets Nouvelle resine anionique a action hypocholesterolemiante, son procede de preparation et compositions therapeutiques la contenant
US4217421A (en) * 1977-06-27 1980-08-12 Rohm And Haas Company Anion exchange resins prepared from crosslinked polystyrenesulfonylchloride
US4380590A (en) * 1978-09-19 1983-04-19 Rohm And Haas Company Emulsion copolymer cation exchange resins
IT1106718B (it) * 1978-12-21 1985-11-18 Alfa Farmaceutici Spa Composizioni a base di resine anioniche salificate farmacologicamente attive
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Also Published As

Publication number Publication date
CH655507B (cs) 1986-04-30
ZA84212B (en) 1984-08-29
CA1218077A (en) 1987-02-17
DE3400491C2 (cs) 1988-11-10
FI840069A0 (fi) 1984-01-09
BE898649A (fr) 1984-07-11
NO840090L (no) 1984-07-13
DK166683B1 (da) 1993-06-28
FI840069A7 (fi) 1984-07-13
IT8447527A0 (it) 1984-01-10
DD218373A5 (de) 1985-02-06
PT77932A (en) 1984-02-01
DZ593A1 (fr) 2004-09-13
PL142737B1 (en) 1987-11-30
PT77932B (en) 1986-07-22
AU2323084A (en) 1984-07-19
NL8400098A (nl) 1984-08-01
AT391467B (de) 1990-10-10
GB2134529B (en) 1986-09-24
IE56545B1 (en) 1991-08-28
FR2542735A1 (fr) 1984-09-21
ZW484A1 (en) 1984-08-08
CS269954B2 (en) 1990-05-14
US4510128A (en) 1985-04-09
SE457959B (sv) 1989-02-13
ES528770A0 (es) 1985-05-01
MTP943B (en) 1984-06-05
IT8447527A1 (it) 1985-07-10
EP0122219A2 (de) 1984-10-17
AR240310A1 (es) 1990-03-30
EP0122219A3 (en) 1985-05-08
DK11884D0 (da) 1984-01-11
KR840007562A (ko) 1984-12-08
PL245656A1 (en) 1985-01-02
FR2542735B1 (fr) 1986-04-18
RO88481A (ro) 1986-01-30
FI82682C (fi) 1991-04-10
KR900006747B1 (ko) 1990-09-20
NO162862C (no) 1990-02-28
NO162862B (no) 1989-11-20
SE8400098D0 (sv) 1984-01-10
AU570230B2 (en) 1988-03-10
JPH0257058B2 (cs) 1990-12-03
ATA784A (de) 1990-04-15
EP0122219B1 (de) 1988-09-21
GR79793B (cs) 1984-10-31
ES8504849A1 (es) 1985-05-01
ATE37378T1 (de) 1988-10-15
PH21795A (en) 1988-02-29
IE840049L (en) 1984-07-12
IL70660A0 (en) 1984-04-30
SE8400098L (sv) 1984-07-13
FI82682B (fi) 1990-12-31
IT1177501B (it) 1987-08-26
MC1564A1 (fr) 1984-11-12
GB8400251D0 (en) 1984-02-08
MA20000A1 (fr) 1984-10-01
DK11884A (da) 1984-07-13
HK90390A (en) 1990-11-09
IL70660A (en) 1987-08-31
NZ206815A (en) 1986-08-08
HU190750B (en) 1986-10-28
LU85171A1 (de) 1984-10-24
GB2134529A (en) 1984-08-15
JPS59134759A (ja) 1984-08-02
EG16562A (en) 1991-12-30
OA07628A (fr) 1985-05-23
DE3400491A1 (de) 1984-07-12
HUT34151A (en) 1985-02-28
DE3474152D1 (en) 1988-10-27

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