CS263485A1 - Rozpustne a biodegradovatelne kopolymery aktivovane pro vazbu biologicky aktivnich latek - Google Patents

Rozpustne a biodegradovatelne kopolymery aktivovane pro vazbu biologicky aktivnich latek

Info

Publication number
CS263485A1
CS263485A1 CS852634A CS263485A CS263485A1 CS 263485 A1 CS263485 A1 CS 263485A1 CS 852634 A CS852634 A CS 852634A CS 263485 A CS263485 A CS 263485A CS 263485 A1 CS263485 A1 CS 263485A1
Authority
CS
Czechoslovakia
Prior art keywords
vazbu
rozpustne
kopolymery
biologicky
biodegradovatelne
Prior art date
Application number
CS852634A
Other languages
English (en)
Other versions
CS254355B1 (en
Inventor
Vladimir Rndr Csc Saudek
Frantisek Rndr Csc Rypacek
Jaroslav Doc Rndr Csc Drobnik
Original Assignee
Vladimir Rndr Csc Saudek
Frantisek Rndr Csc Rypacek
Jaroslav Doc Rndr Csc Drobnik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vladimir Rndr Csc Saudek, Frantisek Rndr Csc Rypacek, Jaroslav Doc Rndr Csc Drobnik filed Critical Vladimir Rndr Csc Saudek
Priority to CS852634A priority Critical patent/CS254355B1/cs
Priority to US06/846,707 priority patent/US4745161A/en
Priority to GB8607916A priority patent/GB2175596B/en
Priority to IT8620010A priority patent/IT1208208B/it
Priority to DE19863612102 priority patent/DE3612102A1/de
Publication of CS263485A1 publication Critical patent/CS263485A1/cs
Publication of CS254355B1 publication Critical patent/CS254355B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Polyamides (AREA)
CS852634A 1985-04-10 1985-04-10 Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances CS254355B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CS852634A CS254355B1 (en) 1985-04-10 1985-04-10 Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances
US06/846,707 US4745161A (en) 1985-04-10 1986-04-01 Soluble and biodegradable polyamino acid activated for bonding of biologically active compound
GB8607916A GB2175596B (en) 1985-04-10 1986-04-01 Biodegradable copolymers activated for bonding of biologically active compounds
IT8620010A IT1208208B (it) 1985-04-10 1986-04-09 Copolimeri solubili e biodegradabili per legare sostanze biologicamente attive.
DE19863612102 DE3612102A1 (de) 1985-04-10 1986-04-10 Loesliche und biologisch abbaubare mischpolymerisate fuer die bindung von biologisch aktiven stoffen und verfahren zu ihrer herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS852634A CS254355B1 (en) 1985-04-10 1985-04-10 Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances

Publications (2)

Publication Number Publication Date
CS263485A1 true CS263485A1 (en) 1987-05-14
CS254355B1 CS254355B1 (en) 1988-01-15

Family

ID=5364033

Family Applications (1)

Application Number Title Priority Date Filing Date
CS852634A CS254355B1 (en) 1985-04-10 1985-04-10 Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances

Country Status (5)

Country Link
US (1) US4745161A (cs)
CS (1) CS254355B1 (cs)
DE (1) DE3612102A1 (cs)
GB (1) GB2175596B (cs)
IT (1) IT1208208B (cs)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0245840B1 (de) * 1986-05-15 1993-12-01 Hoechst Aktiengesellschaft Biologisch abbaubare Polymere für Depotzubereitungen mit kontrollierter Wirkstoffabgabe
USRE35862E (en) * 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
DE3700128A1 (de) * 1987-01-03 1988-07-14 Hoechst Ag Biologisch abbaubare poly- (hydroxyalkyl)- aminodicarbonsaeure-derivate, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
DE3921912A1 (de) * 1989-07-04 1991-01-17 Roehm Gmbh Polyasparaginsaeurederivate als ueberzugsmittel fuer arzneiformen und lebensmittel
FR2658076B1 (fr) * 1990-02-12 1992-06-12 Sanofi Sa Composition cosmetique contenant des copolymeres d'aminoacides, utile comme agent hydratant.
IT1240684B (it) * 1990-04-26 1993-12-17 Tecnopart Srl Poliamminoacidi quali builders per formulazioni detergenti
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
US5197882A (en) * 1990-05-14 1993-03-30 Gary R. Jernberg Periodontal barrier and method for aiding periodontal tissue regeneration agents
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5451410A (en) * 1993-04-22 1995-09-19 Emisphere Technologies, Inc. Modified amino acids for encapsulating active agents
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5578323A (en) * 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
NZ239370A (en) * 1990-08-22 1994-04-27 Merck & Co Inc Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone
DE4217847A1 (de) * 1992-05-29 1993-12-02 Basf Ag Verwendung von Kondensaten der Asparaginsäure als Belagsverhinderer bei der Eindampfung von Zuckersäften
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
ES2244367T3 (es) * 1993-04-22 2005-12-16 Emisphere Technologies, Inc. Composiciones para la administracion por via oral.
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
GB2280600B (en) * 1993-08-06 1997-08-20 British Castors Ltd Furniture supports
CA2215317C (en) 1995-03-24 2002-07-23 Focal, Inc. Reduction of adhesions using controlled delivery of active oxygen inhibitors
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5750147A (en) * 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
WO1997010197A1 (en) * 1995-09-11 1997-03-20 Emisphere Technologies, Inc. METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
EP0866802A1 (en) * 1995-11-21 1998-09-30 Novartis AG Multivalent polymers, processes for their preparation, and their use for preparing biologically active compounds.
AU2595697A (en) * 1996-03-29 1997-10-22 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU3828597A (en) 1996-06-14 1998-01-07 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US5952294A (en) * 1996-07-31 1999-09-14 University Of Pittsburgh Of The Commonwealth System Of Higher Education Peptidyl prodrugs and methods of making and using the same
DE19631379A1 (de) * 1996-08-02 1998-02-05 Basf Ag Wasserlösliche oder wasserdispergierbare Polyasparaginsäure-Derivate, ihre Herstellung und ihre Verwendung
DE19631380A1 (de) * 1996-08-02 1998-02-05 Basf Ag Wasserlösliche oder wasserdispergierbare Polyasparaginsäure-Derivate, ihre Herstellung und ihre Verwendung
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) * 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US6123957A (en) * 1997-07-16 2000-09-26 Jernberg; Gary R. Delivery of agents and method for regeneration of periodontal tissues
US6136950A (en) 1997-09-23 2000-10-24 Mbt Holding Ag Highly efficient cement dispersants
US6066673A (en) * 1998-03-12 2000-05-23 The Procter & Gamble Company Enzyme inhibitors
EP0963758A3 (en) * 1998-05-07 2000-03-22 Universiteit Gent Synthetic polyaminoacid complexes for delivery of nucleic acids to target cells
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
EP1210093A4 (en) * 1999-09-03 2005-01-12 Polytherics Ltd DEGRADABLE POLYMERS
DE10200075A1 (de) 2002-01-03 2003-07-17 Goldschmidt Ag Th Verfahren zur Herstellung von copolymeren hydrophob modifizierten Polyglutaminsäurederivaten und ihre Verwendung
DE10250767A1 (de) * 2002-10-30 2004-06-17 Basf Ag Polyamide
DE602004026747D1 (de) * 2003-09-29 2010-06-02 Nitto Denko Corp Biologisch abbaubare polyacetale für die in-vivo-abgabe von polynucleotiden
US7674452B2 (en) * 2005-03-16 2010-03-09 Nitto Denko Corporation Polymer coating of cells
US7588754B2 (en) * 2005-05-10 2009-09-15 Nitto Denko Corporation Biodegradable polyacetals and methods
US20060263328A1 (en) * 2005-05-19 2006-11-23 Sang Van Hydrophilic polymers with pendant functional groups and method thereof
EP2077290B1 (en) * 2005-12-05 2010-04-21 Nitto Denko Corporation Polyglutamate-amino acid conjugates and methods
US20080181852A1 (en) * 2007-01-29 2008-07-31 Nitto Denko Corporation Multi-functional Drug Carriers
JP2010526159A (ja) * 2007-04-10 2010-07-29 日東電工株式会社 多機能性ポリグルタミン酸塩薬物担体
CN101730549B (zh) * 2007-05-09 2015-12-09 日东电工株式会社 与铂类药物结合的聚合物
EP2155253A2 (en) * 2007-05-09 2010-02-24 Nitto Denko Corporation Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs
ES2430380T3 (es) * 2007-05-09 2013-11-20 Nitto Denko Corporation Composiciones que incluyen un compuesto hidrófobo y un conjugado de poliaminoácido
WO2009111271A1 (en) * 2008-03-06 2009-09-11 Nitto Denko Corporation Polymer paclitaxel conjugates and methods for treating cancer
WO2013154707A1 (en) * 2012-04-12 2013-10-17 Nitto Denko Corporation Co-polymer conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB747901A (en) * 1953-07-01 1956-04-18 Courtaulds Ltd Improvements in and relating to the treatment of synthetic polypeptides
JPS5614690B2 (cs) * 1972-05-18 1981-04-06
JPS5241309B2 (cs) * 1972-10-18 1977-10-18
GB1484031A (en) * 1974-10-15 1977-08-24 Ajinomoto Kk Immobilized biologically active proteins and preparation thereof
US4435547A (en) * 1980-12-29 1984-03-06 Chevron Research Company Stabilized polypyrrolidone end capped with alkanolamine and process for preparing
JPH0917084A (ja) * 1995-07-03 1997-01-17 Matsushita Electric Ind Co Ltd 光ディスクドライブ装置

Also Published As

Publication number Publication date
CS254355B1 (en) 1988-01-15
GB8607916D0 (en) 1986-05-08
GB2175596A (en) 1986-12-03
GB2175596B (en) 1989-06-21
DE3612102A1 (de) 1986-10-16
US4745161A (en) 1988-05-17
IT8620010A0 (it) 1986-04-09
IT1208208B (it) 1989-06-12

Similar Documents

Publication Publication Date Title
CS873086A2 (en) Zpusob smesovani sterkoveho materialu a kapalne zivice a zarizeni k provadeni tohoto zpusobu
CS366986A1 (en) Zapojeni pro dalkove ovladani a dalkovou kontrolu servopohonu
CS276385A1 (en) Zarizeni pro davkovani a dopravu taveniny
CS562385A1 (en) Dvojcinna nesoumerna pneumaticka brzda pro pneumaticke pohomy spanacu vysokeho a velmi vysokeho napeti
CS330585A1 (en) Zarizeni pro mereni prutoku a mnozstvi tekutiny
CS284885A1 (en) Prostredek pro sorpci a desorpci kovovych iontu a zpusob jeho vyroby
CS754485A1 (en) Zapojeni pro bezdotykove mereni utlumu prostredi a objektu
CS20485A2 (en) Rotacka pro soucasny licovy a rubovy tisk
CS839085A1 (en) Zarizeni pro prepousteni kapalin a zkapalnenych plynu
CS633285A1 (en) Zpusob vytvareni behounove vrstvay pneumatiky navalovanim pasku a zarizeni pro kjeho provedeni
CS439285A1 (en) Ostrikovaci zarizeni pro obrabeci a tvareci procesy
CS210085A1 (en) Heterogenni biokatalyzatory pro biotransformace a zpusob jejich pripravy
CS782485A1 (en) Zarizeni pro upevneni izolovanych vodicu a kabelu
CS460085A1 (en) Zarizeni pro synchronizaci casovych zdroju seismologickych a seismoakustickych aparatur
CS757385A1 (en) Zapojeni obvodu pro soubezny zaznam hovoroveho a casoveho signalu
CS843985A1 (en) Zapojeni napajeciho a vazebniho prevodniku pro prenos impulsnich signalu
CS299185A1 (en) Zpusob ziskavani koloidnich suspenzi a zarizeni pro jeho uskutecneni
CS821785A1 (en) Zarizeni pro mereni prutoku a mnozstvi nadojeneho mleka
CS449685A1 (en) Zapojeni pro potlaceni napeti treti harmonicke mezi nulovym a ochrannym vodicem
CS630685A1 (en) Zpusob komplexniho stanoveni teplofyzickych vlastnosti latek a zarizeni pro jeho uskutecneni
CS614185A1 (en) Zapojeni obvodu pro samocinne nulovani a periodickou kontrolu cinnosti mikropocitace
CS366585A1 (en) Zpusob vyroby elektrografickeho ofsetoveho materialu pro stredni a vysoke tiskove naklady
CS804985A1 (en) Zarizeni pro stredove trnove tyce a vylisku lisoderovaci stolice
CS562885A1 (en) Kontaktni ustroji pro tlakoplynove spinace vysokeho a velmi vysokeho napeti
CS194385A1 (en) Hmota pro brousici a lestici telesa