CS363490A3 - Process for preparing novel esters of beta-carboline-3-carboxylic acidsbeing substituted in positions 5 or 6 - Google Patents

Process for preparing novel esters of beta-carboline-3-carboxylic acidsbeing substituted in positions 5 or 6

Info

Publication number: CS363490A3
Authority: CS; Czechoslovakia
Prior art keywords: substituted; carboline; beta; carboxylic; acidsbeing
Prior art date: 1986-03-20

Application number

CS903634A

Other languages

English (en)

Other versions

CS277498B6 (en

Inventor

Helmut Dr Bierre

Andreas Dr Huth

Dieter Dr Rahtz

Ralph Dr Schmiechen

Dieter Dr Seidelmann

Wolfgang Dr Kehr

Herbert Hans Dr Schneider

Mogens Dr Engelstoft

Bondo John Dr Hansen

Frank Dr Watjen

Tage Dr Honore

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-20

Filing date

1986-12-16

Publication date

1992-11-18

1986-12-16 Application filed by Schering Ag filed Critical Schering Ag

1992-11-18 Publication of CS363490A3 publication Critical patent/CS363490A3/cs

1993-02-17 Publication of CS277498B6 publication Critical patent/CS277498B6/cs

Links

ARLVFKCLBYUINL-UHFFFAOYSA-N 9h-pyrido[3,4-b]indole-3-carboxylic acid Chemical compound N1C2=CC=CC=C2C2=C1C=NC(C(=O)O)=C2 ARLVFKCLBYUINL-UHFFFAOYSA-N 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002648 azanetriyl group Chemical group *N(*)* 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Non-Alcoholic Beverages (AREA)
Carbon And Carbon Compounds (AREA)
Heat Sensitive Colour Forming Recording (AREA)
Polyesters Or Polycarbonates (AREA)
Fats And Perfumes (AREA)

CS903634A 1986-03-20 1986-12-16 Process for preparing esters of beta-carboline-3-carboxylic acids being substituted in position 5 or 6 CS277498B6 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863609699 DE3609699A1 (de)	1986-03-20	1986-03-20	5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester

Publications (2)

Publication Number	Publication Date
CS363490A3 true CS363490A3 (en)	1992-11-18
CS277498B6 CS277498B6 (en)	1993-02-17

Family

ID=6297016

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CS903634A CS277498B6 (en)	1986-03-20	1986-12-16	Process for preparing esters of beta-carboline-3-carboxylic acids being substituted in position 5 or 6
CS869386A CS277411B6 (en)	1986-03-20	1986-12-16	Novel esters of beta-carboline-3-carboxylic acids being substituted in position 5 or 6

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CS869386A CS277411B6 (en)	1986-03-20	1986-12-16	Novel esters of beta-carboline-3-carboxylic acids being substituted in position 5 or 6

Country Status (24)

Country	Link
US (2)	US5414002A (cs)
EP (1)	EP0239667B1 (cs)
JP (1)	JPH0670053B2 (cs)
AT (1)	ATE63119T1 (cs)
AU (1)	AU596385B2 (cs)
CA (1)	CA1332837C (cs)
CS (2)	CS277498B6 (cs)
DD (1)	DD260068A5 (cs)
DE (2)	DE3609699A1 (cs)
DK (1)	DK168953B1 (cs)
ES (1)	ES2039346T3 (cs)
FI (2)	FI864498A0 (cs)
GR (1)	GR3002085T3 (cs)
HU (1)	HU195218B (cs)
IE (1)	IE59344B1 (cs)
IL (1)	IL80667A (cs)
MX (1)	MX9203701A (cs)
NO (2)	NO864362D0 (cs)
NZ (1)	NZ218482A (cs)
PH (1)	PH25100A (cs)
PT (1)	PT83763B (cs)
RU (2)	RU1771475C (cs)
UA (2)	UA13475A (cs)
ZA (1)	ZA872072B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4122722A1 (de) *	1991-07-06	1993-01-07	Schering Ag	Verfahren zur herstellung von indol-derivaten
DE19502753A1 (de) *	1995-01-23	1996-07-25	Schering Ag	Neue 9H-Pyrido[3,4-b]indol-Derivate
US20030045541A1 (en) *	2001-07-23	2003-03-06	Christopher Bruckner	GABA-Receptor modulators with NMDA-Antagonistic activity
DE10136842A1 (de) *	2001-07-23	2003-02-13	Schering Ag	GABA¶A¶-Rezeptor-Modulatoren mit NMDA-antagonistischer Aktivität

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ194747A (en) *	1979-08-29	1988-11-29	Schering Ag	9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) *	1980-12-17	1982-07-31	Schering Ag	3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240511A1 (de) *	1982-10-29	1984-05-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur herstellung von ss-carbolinderivaten
DE3322895A1 (de) *	1983-06-23	1985-01-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DE3335323A1 (de) *	1983-09-27	1985-04-04	Schering AG, 1000 Berlin und 4709 Bergkamen	Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DK240184D0 (da) *	1984-05-15	1984-05-15	Ferrosan As	Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DK704488D0 (da) *	1988-12-19	1988-12-19	Novo Industri As	Nye n-substituerede azaheterocykliske carboxylsyrer
DE3504045A1 (de) *	1985-02-04	1986-08-07	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur herstellung von ss-carbolinen durch dehydrierung
DE3540653A1 (de) *	1985-11-13	1987-05-14	Schering Ag	Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) *	1985-12-20	1987-06-25	Schering Ag	5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

1986
- 1986-03-20 DE DE19863609699 patent/DE3609699A1/de not_active Withdrawn
- 1986-10-29 ES ES198686115006T patent/ES2039346T3/es not_active Expired - Lifetime
- 1986-10-29 AT AT86115006T patent/ATE63119T1/de not_active IP Right Cessation
- 1986-10-29 EP EP86115006A patent/EP0239667B1/de not_active Expired - Lifetime
- 1986-10-29 DE DE8686115006T patent/DE3679059D1/de not_active Expired - Lifetime
- 1986-10-31 NO NO864362A patent/NO864362D0/no unknown
- 1986-11-05 FI FI864498A patent/FI864498A0/fi not_active Application Discontinuation
- 1986-11-10 DK DK536386A patent/DK168953B1/da not_active IP Right Cessation
- 1986-11-13 AU AU65168/86A patent/AU596385B2/en not_active Expired
- 1986-11-17 IL IL80667A patent/IL80667A/xx not_active IP Right Cessation
- 1986-11-17 HU HU864740A patent/HU195218B/hu unknown
- 1986-11-18 PT PT83763A patent/PT83763B/pt unknown
- 1986-11-25 IE IE309486A patent/IE59344B1/en not_active IP Right Cessation
- 1986-12-03 NZ NZ218482A patent/NZ218482A/en unknown
- 1986-12-11 FI FI865058A patent/FI83321C/fi not_active IP Right Cessation
- 1986-12-16 CS CS903634A patent/CS277498B6/cs not_active IP Right Cessation
- 1986-12-16 CS CS869386A patent/CS277411B6/cs not_active IP Right Cessation
- 1986-12-17 NO NO865121A patent/NO163737C/no not_active IP Right Cessation
- 1986-12-18 PH PH34618A patent/PH25100A/en unknown
- 1986-12-26 JP JP61308969A patent/JPH0670053B2/ja not_active Expired - Fee Related
- 1986-12-30 DD DD86298773A patent/DD260068A5/de not_active IP Right Cessation
1987
- 1987-01-06 CA CA000526775A patent/CA1332837C/en not_active Expired - Fee Related
- 1987-01-30 UA UA4028879A patent/UA13475A/uk unknown
- 1987-01-30 RU SU874028879A patent/RU1771475C/ru active
- 1987-03-20 ZA ZA872072A patent/ZA872072B/xx unknown
1989
- 1989-10-03 US US07/416,629 patent/US5414002A/en not_active Expired - Lifetime
1991
- 1991-06-07 GR GR91400757T patent/GR3002085T3/el unknown
- 1991-07-30 UA UA5001115A patent/UA26390A/uk unknown
- 1991-07-30 RU SU915001115A patent/RU2034845C1/ru not_active IP Right Cessation
1992
- 1992-06-29 MX MX9203701A patent/MX9203701A/es unknown
1994
- 1994-05-18 US US08/245,278 patent/US5700808A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK536386A (da)	1987-09-21
DD260068A5 (de)	1988-09-14
ZA872072B (en)	1987-09-14
FI83321B (fi)	1991-03-15
PH25100A (en)	1991-02-19
EP0239667B1 (de)	1991-05-02
IE59344B1 (en)	1994-02-09
MX9203701A (es)	1992-09-01
US5700808A (en)	1997-12-23
US5414002A (en)	1995-05-09
CS938686A3 (en)	1992-11-18
NO864362D0 (no)	1986-10-31
DE3609699A1 (de)	1987-09-24
EP0239667A1 (de)	1987-10-07
ATE63119T1 (de)	1991-05-15
RU2034845C1 (ru)	1995-05-10
PT83763B (pt)	1989-07-31
JPH0670053B2 (ja)	1994-09-07
UA13475A (uk)	1997-04-25
DE3679059D1 (de)	1991-06-06
CA1332837C (en)	1994-11-01
FI864498A0 (fi)	1986-11-05
HU195218B (en)	1988-04-28
AU6516886A (en)	1987-09-24
GR3002085T3 (en)	1992-12-30
ES2039346T3 (es)	1993-10-01
FI865058L (fi)	1987-09-21
NO865121L (no)	1987-09-21
IL80667A0 (en)	1987-02-27
IE863094L (en)	1987-09-20
NO163737C (no)	1990-07-11
PT83763A (de)	1986-12-01
JPS62221684A (ja)	1987-09-29
FI83321C (fi)	1991-06-25
NO865121D0 (no)	1986-12-17
DK536386D0 (da)	1986-11-10
IL80667A (en)	1991-04-15
CS277498B6 (en)	1993-02-17
DK168953B1 (da)	1994-07-18
AU596385B2 (en)	1990-05-03
NZ218482A (en)	1990-01-29
RU1771475C (ru)	1992-10-23
CS277411B6 (en)	1993-03-17
FI865058A0 (fi)	1986-12-11
NO163737B (no)	1990-04-02
UA26390A (uk)	1999-08-30
HUT41787A (en)	1987-05-28

Legal Events

Date	Code	Title	Description
2000-06-30	IF00	In force as of 2000-06-30 in czech republic
2007-01-10	MK4A	Patent expired	Effective date: 20061216

Publication	Publication Date	Title
HUT47571A (en)	1989-03-28	Process for production of derivatives of tiazolidindion
WO1988000042A1 (en)	1988-01-14	New 5-alkoxy-2,4-diamino-alkyl benzols, and hair tinting means using them
EP0191507A3 (en)	1986-10-29	New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof
PH24199A (en)	1990-04-10	Derivatives of quinoline carboxylic acid,pharmaceutical composition containing same and process of preparing same
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AU1395283A (en)	1983-11-03	1-carboxyalkanoylindoline-2-carboxylic acid esters
CS363490A3 (en)	1992-11-18	Process for preparing novel esters of beta-carboline-3-carboxylic acidsbeing substituted in positions 5 or 6
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GR3015361T3 (en)	1995-06-30	Process for the preparation of 4-alkoxyalkyl-beta-carbolines.
DE69127396D1 (de)	1997-10-02	Verfahren zur Herstellung von Dihydrofuranonderivaten
AT383811B (de)	1987-08-25	Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten
ZA869400B (en)	1987-08-26	A process for the preparation of 7alpha-acetylthiosteroids