DK0420264T3 - Transdermal indgivelse af (+)(2S,3S)-3-acetoxy-8-chlor-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4-(5H)-on - Google Patents

Transdermal indgivelse af (+)(2S,3S)-3-acetoxy-8-chlor-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4-(5H)-on

Info

Publication number: DK0420264T3
Authority: DK; Denmark
Prior art keywords: benzothiazepine; acetoxy; dimethylaminoethyl; methoxyphenyl; dihydro
Prior art date: 1989-09-29

Application number

DK90118673.4T

Other languages

Danish (da)

English (en)

Inventor

Prakash R Keshary

Donna R Jones

James W Mitchell

Original Assignee

Marion Merrell Dow Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-29

Filing date

1990-09-28

Publication date

1991-06-19

1990-09-28 Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc

1991-06-19 Application granted granted Critical

1991-06-19 Publication of DK0420264T3 publication Critical patent/DK0420264T3/da

Links

GYKFWCDBQAFCLJ-RTWAWAEBSA-N [(2s,3s)-8-chloro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=C(Cl)C=C2S1 GYKFWCDBQAFCLJ-RTWAWAEBSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK90118673.4T 1989-09-29 1990-09-28 Transdermal indgivelse af (+)(2S,3S)-3-acetoxy-8-chlor-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4-(5H)-on DK0420264T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/414,381 US5002773A (en)	1989-09-29	1989-09-29	Transdermal delivery of (+) (2S,3S)-3-acetoxy-8-chloro-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one

Publications (1)

Publication Number	Publication Date
DK0420264T3 true DK0420264T3 (da)	1991-06-19

Family

ID=23641207

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90118673.4T DK0420264T3 (da)	1989-09-29	1990-09-28	Transdermal indgivelse af (+)(2S,3S)-3-acetoxy-8-chlor-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4-(5H)-on

Country Status (6)

Country	Link
US (1)	US5002773A (ja)
EP (1)	EP0420264A3 (ja)
JP (1)	JPH03157332A (ja)
AU (1)	AU628660B2 (ja)
CA (1)	CA2026293A1 (ja)
DK (1)	DK0420264T3 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4963545A (en) *	1988-05-24	1990-10-16	Marion Laboratories, Inc.	Benzothiazepine anti-seizure method
US5383848A (en) *	1990-04-12	1995-01-24	Gensia, Inc.	Iontophoretic administration of drugs
IT1243745B (it) *	1990-10-17	1994-06-21	Vectorpharma Int	Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
US5985317A (en) *	1996-09-06	1999-11-16	Theratech, Inc.	Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
WO2003104257A2 (en) *	2002-05-22	2003-12-18	Smithkline Beecham Corporation	Protease inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3531545A1 (de) *	1985-09-04	1987-03-05	Goedecke Ag	Arzneimittel mit einem gehalt an calcium-antagonisten und deren verwendung
US4879289A (en) *	1988-05-24	1989-11-07	Marion Laboratories, Inc.	Method of ameliorating epileptic seizures

1989
- 1989-09-29 US US07/414,381 patent/US5002773A/en not_active Expired - Fee Related
1990
- 1990-09-26 CA CA002026293A patent/CA2026293A1/en not_active Abandoned
- 1990-09-26 AU AU63644/90A patent/AU628660B2/en not_active Ceased
- 1990-09-28 JP JP2257562A patent/JPH03157332A/ja active Pending
- 1990-09-28 EP EP19900118673 patent/EP0420264A3/en not_active Withdrawn
- 1990-09-28 DK DK90118673.4T patent/DK0420264T3/da active

Also Published As

Publication number	Publication date
EP0420264A3 (en)	1991-06-19
JPH03157332A (ja)	1991-07-05
EP0420264A2 (en)	1991-04-03
US5002773A (en)	1991-03-26
AU6364490A (en)	1991-04-11
AU628660B2 (en)	1992-09-17
CA2026293A1 (en)	1991-03-30

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