DK0432648T3 - Isatinderivater, deres fremstilling og anvendelse - Google Patents

Isatinderivater, deres fremstilling og anvendelse

Info

Publication number
DK0432648T3
DK0432648T3 DK90123474.0T DK90123474T DK0432648T3 DK 0432648 T3 DK0432648 T3 DK 0432648T3 DK 90123474 T DK90123474 T DK 90123474T DK 0432648 T3 DK0432648 T3 DK 0432648T3
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
branched
compounds
independently
Prior art date
Application number
DK90123474.0T
Other languages
Danish (da)
English (en)
Inventor
Frank Waetjen
Jorgen Drejer
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK624889A external-priority patent/DK624889D0/da
Priority claimed from DK647089A external-priority patent/DK647089D0/da
Priority claimed from DK8590A external-priority patent/DK8590D0/da
Priority claimed from DK8690A external-priority patent/DK8690D0/da
Priority claimed from DK36390A external-priority patent/DK36390D0/da
Priority claimed from DK209390A external-priority patent/DK209390D0/da
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of DK0432648T3 publication Critical patent/DK0432648T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
  • Holo Graphy (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90123474.0T 1989-12-11 1990-12-06 Isatinderivater, deres fremstilling og anvendelse DK0432648T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK624889A DK624889D0 (da) 1989-12-11 1989-12-11 Forbindelser og anvendelse
DK647089A DK647089D0 (da) 1989-12-19 1989-12-19 Forbindelser og anvendelse
DK8590A DK8590D0 (da) 1990-01-12 1990-01-12 Forbindelser og anvendelse
DK8690A DK8690D0 (da) 1990-01-12 1990-01-12 Forbindelser og anvendelse
DK36390A DK36390D0 (da) 1990-02-12 1990-02-12 Forbindelser og anvendelse
DK209390A DK209390D0 (da) 1990-08-31 1990-08-31 Kondenserede lactamforbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK0432648T3 true DK0432648T3 (da) 1995-11-06

Family

ID=27545140

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90123474.0T DK0432648T3 (da) 1989-12-11 1990-12-06 Isatinderivater, deres fremstilling og anvendelse

Country Status (14)

Country Link
EP (1) EP0432648B1 (pt)
JP (1) JP3057095B2 (pt)
AT (1) ATE125795T1 (pt)
AU (1) AU629075B2 (pt)
CA (1) CA2031756C (pt)
DE (1) DE69021347T2 (pt)
DK (1) DK0432648T3 (pt)
ES (1) ES2077623T3 (pt)
FI (1) FI100880B (pt)
GR (1) GR3017487T3 (pt)
IE (1) IE69677B1 (pt)
NO (1) NO174464C (pt)
NZ (1) NZ236200A (pt)
PT (1) PT96162B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164404A (en) * 1991-03-15 1992-11-17 Neurosearch A/S Hydrazone derivatives and their use
AU655643B2 (en) * 1991-07-09 1995-01-05 Neurosearch A/S Novel isatineoxime derivatives, their preparation and use
US5223527A (en) * 1991-07-09 1993-06-29 Neurosearch A/S Isatineoxime derivatives and their use
CA2076948C (en) * 1991-08-28 2002-04-16 Frank Watjen Isatineoxime derivatives, their preparation and use
DK69693D0 (da) * 1993-06-14 1993-06-14 Neurosearch As Farven lilla
US5565580A (en) * 1994-01-27 1996-10-15 Neurosearch A/S Glutamate Antagonists
AU687255B2 (en) * 1994-09-14 1998-02-19 Neurosearch A/S Indole-2,3-dione-3-oxime derivatives, their preparation and use
UA54403C2 (uk) * 1996-10-01 2003-03-17 Н'Юросерч А/С Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму
KR19980050063A (ko) * 1996-12-20 1998-09-15 이덕림 신규한 하이드라존 유도체
KR20010041625A (ko) 1998-03-06 2001-05-25 아스트라제네카 악티에볼라그 신규 용도
EP1135123B1 (en) 1998-12-04 2004-12-29 Neurosearch A/S Use of isatin derivatives as ion channel activating agents
WO2000071102A2 (en) * 1999-05-19 2000-11-30 Neurosearch A/S Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders
EP1736468A3 (en) * 2000-01-24 2007-01-03 NeuroSearch A/S Isatin derivatives with neurotrophic activity useful in the treatment of diseases mediated by the nerve growth factor (NGF) activation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR65270B (en) * 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
NO905320L (no) 1991-06-12
NO174464C (no) 1994-05-11
NZ236200A (en) 1994-12-22
ATE125795T1 (de) 1995-08-15
GR3017487T3 (en) 1995-12-31
PT96162B (pt) 1998-04-30
EP0432648B1 (en) 1995-08-02
FI905943A0 (fi) 1990-12-03
AU6792090A (en) 1991-06-13
FI100880B (fi) 1998-03-13
NO905320D0 (no) 1990-12-10
JPH03204856A (ja) 1991-09-06
EP0432648A2 (en) 1991-06-19
CA2031756C (en) 2002-06-11
ES2077623T3 (es) 1995-12-01
FI905943L (fi) 1991-06-12
JP3057095B2 (ja) 2000-06-26
DE69021347D1 (de) 1995-09-07
IE69677B1 (en) 1996-10-02
DE69021347T2 (de) 1996-01-04
EP0432648A3 (en) 1991-09-25
NO174464B (no) 1994-01-31
AU629075B2 (en) 1992-09-24
CA2031756A1 (en) 1991-06-12
PT96162A (pt) 1991-09-30
IE904175A1 (en) 1991-06-19

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