DK0787115T3 - Fremgangsmåde til fremstilling af 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepinderivater - Google Patents

Fremgangsmåde til fremstilling af 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepinderivater

Info

Publication number: DK0787115T3
Authority: DK; Denmark
Prior art keywords: benzofuro; hexahydro; preparation; benzazepine derivatives; benzazepine
Prior art date: 1994-10-21

Application number

DK95944807T

Other languages

Danish (da)

English (en)

Inventor

Ulrich Jordis

Enburg Bernhard K

Laszlo Czollner

Johannes Frihlich

Original Assignee

Sanochemia Pharmazeutika Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-21

Filing date

1995-10-23

Publication date

2000-05-08

1994-10-21 Priority claimed from AT198094A external-priority patent/AT401058B/de

1995-10-23 Application filed by Sanochemia Pharmazeutika Ag filed Critical Sanochemia Pharmazeutika Ag

2000-05-08 Application granted granted Critical

2000-05-08 Publication of DK0787115T3 publication Critical patent/DK0787115T3/da

Links

WGJYTAVHUDKGNK-UHFFFAOYSA-N O1C(C2=3)=CC=CC=3CNCCC22C1CCC=C2 Chemical class O1C(C2=3)=CC=CC=3CNCCC22C1CCC=C2 WGJYTAVHUDKGNK-UHFFFAOYSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)

DK95944807T 1994-10-21 1995-10-23 Fremgangsmåde til fremstilling af 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepinderivater DK0787115T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AT198094A AT401058B (de)	1994-10-21	1994-10-21	Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
US48710295A	1995-06-07	1995-06-07
PCT/AT1995/000208 WO1996012692A1 (fr)	1994-10-21	1995-10-23	PROCEDE DE PREPARATION DE DERIVES DE 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO[3a,3,2-ef][2]BENZAZEPINE

Publications (1)

Publication Number	Publication Date
DK0787115T3 true DK0787115T3 (da)	2000-05-08

Family

ID=25597335

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95944807T DK0787115T3 (da)	1994-10-21	1995-10-23	Fremgangsmåde til fremstilling af 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepinderivater

Country Status (27)

Country	Link
US (1)	US6043359A (fr)
EP (1)	EP0787115B1 (fr)
JP (1)	JP4187786B2 (fr)
KR (1)	KR100352212B1 (fr)
CN (1)	CN1069624C (fr)
AT (1)	ATE188460T1 (fr)
AU (1)	AU695352B2 (fr)
BG (1)	BG62133B1 (fr)
BR (1)	BR9509406A (fr)
CA (1)	CA2203183C (fr)
CZ (1)	CZ295528B6 (fr)
DE (1)	DE59507585D1 (fr)
DK (1)	DK0787115T3 (fr)
ES (1)	ES2106700T3 (fr)
FI (1)	FI114477B (fr)
GR (2)	GR980300015T1 (fr)
HU (1)	HU217207B (fr)
MX (1)	MX9702892A (fr)
NO (2)	NO313234B1 (fr)
NZ (1)	NZ294191A (fr)
PL (1)	PL184590B1 (fr)
PT (1)	PT787115E (fr)
RO (1)	RO118419B1 (fr)
RU (1)	RU2146258C1 (fr)
SI (1)	SI0787115T1 (fr)
SK (1)	SK283877B6 (fr)
WO (1)	WO1996012692A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9519267D0 (en) *	1995-09-21	1995-11-22	Chiroscience Ltd	Preparation of alkaloids
AT403803B (de)	1996-04-19	1998-05-25	Sanochemia Ltd	Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
GB9610887D0 (en) *	1996-05-24	1996-07-31	N H S Trust	Process
GB9707413D0 (en) *	1997-04-11	1997-05-28	Chiroscience Ltd	Process
ATE263171T1 (de)	2000-03-31	2004-04-15	Sanochemia Pharmazeutika Ag	Neue derivate und analoga von galanthamin
US6897228B2 (en) *	2000-07-07	2005-05-24	Medicure International Inc.	Pyridoxine and pyridoxal analogues: new uses
WO2002061457A2 (fr) *	2001-01-30	2002-08-08	Decharms R Christopher	Procedes de surveillance physiologique, d'entrainement, d'exercice et de regulation
DE10129265A1 (de) *	2001-06-18	2003-01-02	Hf Arzneimittelforsch Gmbh	Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
DE10134038A1 (de) *	2001-07-12	2003-02-06	Hf Arzneimittelforsch Gmbh	Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
US20060111341A1 (en) *	2003-09-29	2006-05-25	Angelika Bodenteich	Use of galanthamine and the derivatives thereof in the production of medicaments
AT414125B (de) *	2003-09-29	2006-09-15	Sanochemia Pharmazeutika Ag	Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
WO2005065662A1 (fr) *	2003-12-31	2005-07-21	Actavis Group Hf	Formulations solides d'administration de galantamine
CA2551946A1 (fr) *	2003-12-31	2005-07-21	Actavis Group Hf	Formulations de galantamine
WO2006013546A2 (fr) *	2004-07-28	2006-02-09	Ranbaxy Laboratories Limited	Procede de preparation de galantamine pure
WO2006018703A2 (fr) *	2004-08-16	2006-02-23	Ranbaxy Laboratories Limited	Procedes de preparation de la narwedine et son utilisation dans la synthese de galantamine
AR054753A1 (es) *	2005-05-03	2007-07-11	Medichem Sa	Sintesis y preparaciones de narwedina galantamina y compuestos relacionados
AT504663B1 (de) *	2007-02-22	2008-07-15	Sanochemia Pharmazeutika Ag	Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten
NZ580271A (en)	2007-04-12	2011-03-31	Scinopharm Taiwan Ltd	Process for making galantamine
EP2009015B1 (fr)	2007-06-18	2012-01-11	Aurobindo Pharma Limited	Procédé pour la préparation de bromhydrate de galantamine
AT507039A1 (de) *	2008-06-26	2010-01-15	Sanochemia Pharmazeutika Ag	Verfahren zum herstellen von hochreinen benzazepinderivaten
DE102008056086A1 (de) *	2008-11-06	2010-05-12	Gp Solar Gmbh	Additiv für alkalische Ätzlösungen, insbesondere für Texturätzlösungen sowie Verfahren zu dessen Herstellung
WO2013160728A1 (fr)	2012-04-26	2013-10-31	Alma Mater Studiorum - Universita' Di Bologna	Composés à double ciblage pour le traitement de la maladie d'alzheimer
CN102924462B (zh) *	2012-10-24	2015-01-14	华东师范大学	1,2,3,4,5,9-取代苯并吖庚因类化合物的合成方法
CN103345954B (zh) *	2013-06-20	2016-06-08	哈尔滨工业大学	一种高锰酸盐与活性炭联用去除放射性碘污染的水处理方法
CN109336897A (zh) *	2018-12-06	2019-02-15	河南中帅医药科技股份有限公司	一种氢溴酸加兰他敏工业化制备方法
CN112521364B (zh) *	2019-09-17	2023-09-05	鲁南制药集团股份有限公司	一种加兰他敏中间体化合物v
CN112521395B (zh) *	2019-09-17	2023-09-05	鲁南制药集团股份有限公司	一种加兰他敏的制备方法
CN110714208B (zh) *	2019-10-30	2020-12-29	常州工学院	一种电催化制备6-(磺酰甲基)菲啶类化合物的方法
CN118908968B (zh) *	2024-10-09	2025-03-04	威胜生物医药(苏州)股份有限公司	一种加兰他敏中间体衍生物及其催化氧化制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BG28325A1 (en) *	1978-11-21	1980-04-15	Vlakhov	Method of obtaining of enons navedine type and their derivatives
US4290862A (en) *	1979-11-14	1981-09-22	Edinen Centar P Chimia	Method for the preparation of narwedine-type enones
US4663318A (en) *	1986-01-15	1987-05-05	Bonnie Davis	Method of treating Alzheimer's disease
EP0363415B1 (fr) *	1987-05-04	2008-10-15	Davis, Bonnie	Composes permettant le traitement de la maladie d'alzheimer
US5428159A (en) *	1994-04-08	1995-06-27	Ciba-Geigy Corporation	Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

1995
- 1995-10-23 WO PCT/AT1995/000208 patent/WO1996012692A1/fr not_active Ceased
- 1995-10-23 HU HU9800766A patent/HU217207B/hu unknown
- 1995-10-23 RU RU97107848A patent/RU2146258C1/ru active
- 1995-10-23 JP JP51352796A patent/JP4187786B2/ja not_active Expired - Fee Related
- 1995-10-23 AT AT95944807T patent/ATE188460T1/de active
- 1995-10-23 KR KR1019970702612A patent/KR100352212B1/ko not_active Expired - Lifetime
- 1995-10-23 DK DK95944807T patent/DK0787115T3/da active
- 1995-10-23 SI SI9530182T patent/SI0787115T1/xx unknown
- 1995-10-23 CA CA002203183A patent/CA2203183C/fr not_active Expired - Lifetime
- 1995-10-23 SK SK483-97A patent/SK283877B6/sk not_active IP Right Cessation
- 1995-10-23 ES ES95944807T patent/ES2106700T3/es not_active Expired - Lifetime
- 1995-10-23 CZ CZ19971195A patent/CZ295528B6/cs not_active IP Right Cessation
- 1995-10-23 RO RO97-00721A patent/RO118419B1/ro unknown
- 1995-10-23 DE DE59507585T patent/DE59507585D1/de not_active Expired - Lifetime
- 1995-10-23 BR BR9509406A patent/BR9509406A/pt not_active Application Discontinuation
- 1995-10-23 NZ NZ294191A patent/NZ294191A/xx not_active IP Right Cessation
- 1995-10-23 EP EP95944807A patent/EP0787115B1/fr not_active Expired - Lifetime
- 1995-10-23 PT PT95944807T patent/PT787115E/pt unknown
- 1995-10-23 PL PL95319754A patent/PL184590B1/pl unknown
- 1995-10-23 AU AU36938/95A patent/AU695352B2/en not_active Expired
- 1995-10-23 CN CN95196432A patent/CN1069624C/zh not_active Expired - Lifetime
1997
- 1997-04-10 NO NO19971645A patent/NO313234B1/no not_active IP Right Cessation
- 1997-04-16 FI FI971609A patent/FI114477B/fi not_active IP Right Cessation
- 1997-04-16 BG BG101417A patent/BG62133B1/bg unknown
- 1997-04-18 US US08/839,350 patent/US6043359A/en not_active Expired - Lifetime
- 1997-04-18 NO NO971796A patent/NO971796L/no unknown
- 1997-04-21 MX MX9702892A patent/MX9702892A/es unknown
1998
- 1998-03-31 GR GR980300015T patent/GR980300015T1/el unknown
2000
- 2000-03-15 GR GR20000400665T patent/GR3032965T3/el unknown

Also Published As

Publication number	Publication date
EP0787115A1 (fr)	1997-08-06
CA2203183C (fr)	2008-04-08
JPH10507457A (ja)	1998-07-21
AU3693895A (en)	1996-05-15
SK283877B6 (sk)	2004-04-06
DE59507585D1 (de)	2000-02-10
ATE188460T1 (de)	2000-01-15
FI114477B (fi)	2004-10-29
KR100352212B1 (ko)	2003-04-18
AU695352B2 (en)	1998-08-13
NO971796L (no)	1997-05-28
HUT77716A (hu)	1998-07-28
PL184590B1 (pl)	2002-11-29
HU217207B (hu)	1999-12-28
NO971796D0 (no)	1997-04-18
FI971609A0 (fi)	1997-04-16
NO313234B1 (no)	2002-09-02
PL319754A1 (en)	1997-08-18
MX9702892A (es)	1998-07-31
ES2106700T3 (es)	2000-05-16
CN1069624C (zh)	2001-08-15
JP4187786B2 (ja)	2008-11-26
WO1996012692A1 (fr)	1996-05-02
BG101417A (en)	1997-12-30
US6043359A (en)	2000-03-28
BR9509406A (pt)	1998-11-03
SK48397A3 (en)	1997-11-05
CN1170395A (zh)	1998-01-14
EP0787115B1 (fr)	2000-01-05
CZ295528B6 (cs)	2005-08-17
CA2203183A1 (fr)	1996-05-02
NO971645D0 (no)	1997-04-10
GR3032965T3 (en)	2000-07-31
SI0787115T1 (en)	2000-04-30
CZ119597A3 (en)	1997-08-13
RO118419B1 (ro)	2003-05-30
BG62133B1 (bg)	1999-03-31
FI971609L (fi)	1997-06-02
ES2106700T1 (es)	1997-11-16
NZ294191A (en)	1998-10-28
PT787115E (pt)	2000-05-31
RU2146258C1 (ru)	2000-03-10
NO971645L (no)	1997-05-07
GR980300015T1 (en)	1998-03-31

Publication	Publication Date	Title
DK0787115T3 (da)	2000-05-08	Fremgangsmåde til fremstilling af 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepinderivater
ZA968957B (en)	1998-04-24	Process for the preparation of dihaloazolopyrimidines.
NO981800L (no)	1998-06-11	FremgangsmÕte for fremstilling av 1,1,1,3,3-pentafluorpentan
DZ2135A1 (fr)	2002-07-23	Procédé de préparation de mélamine pure.
DK0839138T3 (da)	2004-09-27	Fremgangsmåde til fremstilling af N-substituerede 3-hydroxypyrazoler
EP0671206A3 (fr)	1995-11-08	Procédé de préparation de microcapsules.
EP0669363A3 (fr)	1996-05-01	Procédé de préparation de polyorganosilane.
DK0815092T3 (da)	1999-12-06	Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner
ZA968550B (en)	1998-04-14	Novel processes for the preparation of anti-malarial compounds.
FI952145L (fi)	1995-11-07	Menetelmä alfa-D-glukopyranosido-1,6-mannitolin ja -sorbitolin valmistamiseksi alfa-D-glukopyrano-sido-1,6-fruktoosista
NO985535D0 (no)	1998-11-27	FremgangsmÕte for fremstilling av 1,3-alkandioler
DK0721929T3 (da)	2000-03-27	Fremgangsmåde til fremstilling af hydroxyalkoxybenzophenoner
NO303495B1 (no)	1998-07-20	FremgangsmÕte til fremstilling av N-alkyl-laktamer
NO20013219D0 (no)	2001-06-27	Fremgangsmåte for fremstilling av trinatrium-pentacyanoamino- ferrat (II)
IL118731A0 (en)	1996-10-16	Process for the preparation of 2,2-dialkyl-arylidene-cycloalkanones
NO20005743L (no)	2001-01-03	Fremgangsmåte til fremstilling av 4,5-epoksymorfinan-6- glukuronider
DK0783491T3 (da)	2002-01-21	Fremgangsmåde til fremstilling af 3,3,5-trichlorglutarimid
HU9500962D0 (en)	1995-05-29	Process for the preparation of substituted, nitrogen containing heterocyclic compounds
WO1999040078A3 (fr)	1999-10-07	Procede de preparation de sotolon
FR2700334B1 (fr)	1995-03-10	Procédé de préparation de fuchsones.
EP0628634A3 (fr)	1995-09-06	Procédé de préparation de la serine-hydroxyméthyltransferase.
WO1999051573A3 (fr)	1999-12-02	Procede de preparation d'un compose de 2-oxopyrrolidine
IL119112A0 (en)	1996-11-14	Process for the preparation of 4,6-dichloropyrimidines
IL139521A0 (en)	2001-11-25	Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides