DK0817797T3 - Glycopeptidantibiotikumderivater - Google Patents

Glycopeptidantibiotikumderivater

Info

Publication number: DK0817797T3
Authority: DK; Denmark
Prior art keywords: glycopeptide antibiotic; derivative compounds; antibiotic derivatives; activity against; derivatives
Prior art date: 1995-03-24

Application number

DK96909713T

Other languages

English (en)

Inventor

Robin D G Cooper

Bret E Huff

Thalia I Nicas

Michael J Rodriguez

Mark J Zweifel

Michael A Staszak

Stephen C Wilkie

John T Quatroche

Nancy J Snyder

Richard C Thompson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-24

Filing date

1996-03-14

Publication date

2007-05-07

1996-03-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2007-05-07 Application granted granted Critical

2007-05-07 Publication of DK0817797T3 publication Critical patent/DK0817797T3/da

Links

MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical class O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title abstract 2
-1 glycopeptide antibiotic derivative compounds Chemical class 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
108010059993 Vancomycin Proteins 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229960003165 vancomycin Drugs 0.000 abstract 1
MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compounds Of Unknown Constitution (AREA)

DK96909713T 1995-03-24 1996-03-14 Glycopeptidantibiotikumderivater DK0817797T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/410,155 US5840684A (en)	1994-01-28	1995-03-24	Glycopeptide antibiotic derivatives
PCT/US1996/003550 WO1996030401A1 (en)	1995-03-24	1996-03-14	Glycopeptide antibiotic derivatives

Publications (1)

Publication Number	Publication Date
DK0817797T3 true DK0817797T3 (da)	2007-05-07

Family

ID=23623466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96909713T DK0817797T3 (da)	1995-03-24	1996-03-14	Glycopeptidantibiotikumderivater

Country Status (10)

Country	Link
US (2)	US5840684A (da)
EP (1)	EP0817797B1 (da)
JP (1)	JPH11502534A (da)
AT (1)	ATE349464T1 (da)
AU (1)	AU5312196A (da)
DE (1)	DE69636791T2 (da)
DK (1)	DK0817797T3 (da)
ES (1)	ES2274525T3 (da)
PT (1)	PT817797E (da)
WO (1)	WO1996030401A1 (da)

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KR100856479B1 (ko) *	2000-05-02	2008-09-04	세라밴스 인코포레이티드	환원성 알킬화 방법
JP4870314B2 (ja) *	2000-05-02	2012-02-08	セラヴァンス，インコーポレーテッド	シクロデキストリンを含むグリコペプチド抗生物質組成物
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EP1534316A2 (en) *	2002-08-30	2005-06-01	K.U. Leuven Research and Development	Glycopeptide antibiotics and semisynthetic derivatives thereof and their use as antiviral agents
ATE381957T1 (de) *	2003-07-22	2008-01-15	Theravance Inc	Verwendung eines antimykotischen echinocandin- mittels in kombination mit einem antibakteriellen glycopeptid-mittel
CA2588285A1 (en) *	2004-11-29	2006-06-01	National University Corporation Nagoya University	Glycopeptide antibiotic monomer derivatives
US20070185015A1 (en) *	2005-02-28	2007-08-09	Chiron Corporation and North China Pharmaceutical Corporation	Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7368422B2 (en) *	2005-02-28	2008-05-06	Novartis Vaccines And Diagnostics Inc.	Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) *	2005-02-28	2009-12-15	Novartis Vaccines And Diagnostics, Inc.	Semi-synthetic glycopeptides with antibiotic activity
UA90707C2 (en) *	2005-04-06	2010-05-25	Астразенека Аб	Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
AR053347A1 (es) *	2005-04-06	2007-05-02	Astrazeneca Ab	Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
CA2623239C (en)	2005-09-22	2016-07-12	Medivas, Llc	Solid polymer delivery compositions and methods for use thereof
JP5192384B2 (ja)	2005-09-22	2013-05-08	メディバスエルエルシー	ビス−（α−アミノ）−ジオール−ジエステル含有ポリ（エステルアミド）およびポリ（エステルウレタン）組成物および使用の方法
WO2007084507A2 (en) *	2006-01-13	2007-07-26	The Scripps Research Institute	[ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en)	2006-05-26	2008-02-16	Shionogi & Co	Glycopeptide antibiotic derivatives
ES2445941T3 (es)	2006-09-25	2014-03-06	The Medicines Company	Uso de oritavancina para la prevención y el tratamiento del ántrax
EP2097440A4 (en)	2006-12-22	2010-09-08	Targanta Therapeutics Inc	ANTIBIOTICS BASED ON GLYCOPEPTIDES AND LIPOGLYCOPEPTIDES PHOSPHONES AND THEIR USES IN THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS
CN101959900A (zh)	2007-12-26	2011-01-26	盐野义制药株式会社	糖肽类抗生素糖基化衍生物
EP2260060A4 (en)	2008-04-01	2013-01-16	Univ Cornell	ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM
US10201587B2 (en)	2008-04-08	2019-02-12	Melinta Therapeutics, Inc.	Methods of inhibiting and treating biofilms using glycopeptide antibiotics
PT3006038T (pt)	2008-08-30	2024-08-23	The Medicines Co	Doses únicas de oritavancina para tratamento ou prevenção de uma infeção bacteriana
AU2010245097B2 (en)	2009-04-28	2015-08-13	Melinta Therapeutics, Inc.	Methods of treating bacterial infections using oritavancin
ES2613806T3 (es)	2011-07-26	2017-05-26	The Medicines Company	Ensayo de difusión con disco para oritavancina
CA2904387C (en)	2013-03-15	2021-12-07	Melinta Therapeutics, Inc.	Methods of treating infections in overweight and obese patients using antibiotics
CN104418941B (zh)	2013-08-19	2017-11-07	爱斯医药科技(南京)有限公司	万古霉素衍生物、制备方法及其应用
LT3038616T (lt)	2013-08-26	2023-05-25	Melinta Therapeutics, Inc.	Bakteriemijos ir osteomielito gydymo būdai naudojant oritavanciną
IN2013CH04314A (da)	2013-09-23	2015-08-28	Jawaharlal Nehru Ct For Advanced Scient Res Jncasr
GB201402267D0 (en)	2014-02-10	2014-03-26	Cambridge Entpr Ltd	Antibacterial agents
CA2954653C (en) *	2014-07-10	2023-01-24	The Scripps Research Institute	N-(hydrophobe-substituted)vancosaminyl [.psi.[c(=nh)nh]tpg4]vancomycin and [.psi.[ch2nh]tpg4]vancomycin
EP4509178A3 (en)	2014-07-17	2025-06-25	Melinta Therapeutics, LLC	High purity oritavancin and method of producing same
US20170342110A1 (en) *	2014-12-25	2017-11-30	Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR)	Glycopeptides and uses thereof
US10561648B2 (en) *	2016-01-11	2020-02-18	Stc.Unm	Inhibition and treatment of bacterial infections by sex-specific GPER targeting
JP6671972B2 (ja) *	2016-01-15	2020-03-25	キヤノン株式会社	ファクシミリ装置、閾値設定方法、及びプログラム
RU2018129076A (ru)	2016-02-18	2020-03-18	Мелинта Терапьютикс, Инк.	Составы оритаванцина
WO2017179003A1 (en)	2016-04-15	2017-10-19	Lupin Limited	Topical compositions for ophthalmic and otic use
CN107619433B (zh) *	2016-07-15	2023-03-17	上海来益生物药物研究开发中心有限责任公司	糖肽类衍生物及其药学可接受的盐、制备方法和应用
CN108409837B (zh) *	2018-03-06	2021-09-24	上海来益生物药物研究开发中心有限责任公司	一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用

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AU2441697A (en) *	1996-04-12	1997-11-07	Eli Lilly And Company	Covalently-linked glycopeptide dimers
US5919756A (en) *	1996-06-28	1999-07-06	Eli Lilly And Company	Amides
US5977063A (en) *	1997-05-20	1999-11-02	Eli Lilly And Company	Alkylated hexapeptides

1995
- 1995-03-24 US US08/410,155 patent/US5840684A/en not_active Expired - Lifetime
1996
- 1996-03-14 DK DK96909713T patent/DK0817797T3/da active
- 1996-03-14 ES ES96909713T patent/ES2274525T3/es not_active Expired - Lifetime
- 1996-03-14 AU AU53121/96A patent/AU5312196A/en not_active Abandoned
- 1996-03-14 EP EP96909713A patent/EP0817797B1/en not_active Expired - Lifetime
- 1996-03-14 PT PT96909713T patent/PT817797E/pt unknown
- 1996-03-14 DE DE69636791T patent/DE69636791T2/de not_active Expired - Lifetime
- 1996-03-14 WO PCT/US1996/003550 patent/WO1996030401A1/en not_active Ceased
- 1996-03-14 AT AT96909713T patent/ATE349464T1/de active
- 1996-03-14 JP JP8529455A patent/JPH11502534A/ja active Pending
1998
- 1998-04-17 US US09/062,235 patent/US5977062A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU5312196A (en)	1996-10-16
PT817797E (pt)	2007-02-28
DE69636791T2 (de)	2007-10-11
ES2274525T3 (es)	2007-05-16
WO1996030401A1 (en)	1996-10-03
DE69636791D1 (de)	2007-02-08
US5840684A (en)	1998-11-24
ATE349464T1 (de)	2007-01-15
JPH11502534A (ja)	1999-03-02
EP0817797A4 (en)	2000-12-06
US5977062A (en)	1999-11-02
EP0817797B1 (en)	2006-12-27
EP0817797A1 (en)	1998-01-14

Publication	Publication Date	Title
DK0817797T3 (da)	2007-05-07	Glycopeptidantibiotikumderivater
MY128335A (en)	2007-01-31	Glycopeptide antibiotic derivatives
ES2131496T3 (es)	1999-08-01	Mejoras relativas a derivados glicopeptidicos.
NO970210L (no)	1997-07-21	Heteroatomholdige cyklopentanopyridyl-oksazolidinoner
DE59410450D1 (de)	2007-05-24	Implantat für den zwischenwirbelraum
EP0847238A4 (en)	2000-04-19	Seeding heart valves
DE69602638D1 (de)	1999-07-08	Naphthylverbindungen, Zwischenprodukte, Zusammensetzungen und Methoden
DE69619717D1 (de)	2002-04-18	Verbesserte Schlitzventiltür
WO1996032003A3 (en)	1997-01-03	Tetrahydroimidazopyridoindolediones and their use as medicaments
YU48666B (sh)	1999-06-15	Mometason furoat monohidrat i postupak za njegovo dobijanje
FI980862A0 (fi)	1998-04-17	Kiraalisia metyylifenyylioksatsolidinoneja
MX9700885A (es)	1998-04-30	Nuevas heteroariloxazolidinonas.
BR9913225A (pt)	2001-05-22	Novos agentes antibacterianos de isoxazolinona
DK0920421T3 (da)	2003-03-10	Isoxazolinderivater anvendelige som antimikrobielle midler
DK0824535T3 (da)	2003-06-02	Antibakterielle cephalosporinforbindelser.
DE59610952D1 (de)	2004-05-06	Einzel-Elektrodensonde für Zweikammer-Herzschrittmachersysteme, insbesondere für DDD-Herzschrittmachersysteme
PY0101314A (es)	2001-12-03	Compuestos farmaceuticos
NO980296D0 (no)	1998-01-23	Forbedrede terapeutiske midler
DE69618694D1 (de)	2002-03-14	N-Acetylpiperazinderivat, antibakteriell und anti-ulcer Medikament
CA2216167A1 (en)	1996-10-03	Glycopeptide antibiotic derivatives
BG101983A (en)	1998-04-30	Substituted phenylamidines, medicamentous forms containing them and mehtod for their preparation
RU94028649A (ru)	1996-06-20	Оксимные производные с цефалоспорановой структурой, способ их получения и промежуточные соединения
BR9510036A (pt)	1997-10-28	Derivados de 1,3,4-oxadiazina
DK0828715T3 (da)	2001-10-08	N-Oxider som antibakterielle midler
KR970020882U (ko)	1997-06-18	오존 살균 가구