DK0841943T3 - Avirulente herpesvira anvendelige som tumordræbende midler og vacciner - Google Patents
Avirulente herpesvira anvendelige som tumordræbende midler og vaccinerInfo
- Publication number
- DK0841943T3 DK0841943T3 DK96927257T DK96927257T DK0841943T3 DK 0841943 T3 DK0841943 T3 DK 0841943T3 DK 96927257 T DK96927257 T DK 96927257T DK 96927257 T DK96927257 T DK 96927257T DK 0841943 T3 DK0841943 T3 DK 0841943T3
- Authority
- DK
- Denmark
- Prior art keywords
- viruses
- neoplastic cells
- herpetic
- avirulent
- tumoricidal
- Prior art date
Links
- 241001529453 unidentified herpesvirus Species 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 8
- 210000005170 neoplastic cell Anatomy 0.000 abstract 5
- 230000002476 tumorcidal effect Effects 0.000 abstract 3
- 241000700584 Simplexvirus Species 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000000508 neurotrophic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000003362 replicative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US160295P | 1995-07-27 | 1995-07-27 | |
| PCT/US1996/012281 WO1997004804A1 (en) | 1995-07-27 | 1996-07-25 | Avirulent herpetic viruses useful as tumoricidal agents and vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0841943T3 true DK0841943T3 (da) | 2003-12-08 |
Family
ID=21696918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96927257T DK0841943T3 (da) | 1995-07-27 | 1996-07-25 | Avirulente herpesvira anvendelige som tumordræbende midler og vacciner |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0841943B1 (da) |
| AT (1) | ATE248604T1 (da) |
| AU (1) | AU725557B2 (da) |
| CA (1) | CA2227860C (da) |
| DE (1) | DE69629819T2 (da) |
| DK (1) | DK0841943T3 (da) |
| ES (1) | ES2205053T3 (da) |
| IL (1) | IL118942A (da) |
| WO (1) | WO1997004804A1 (da) |
| ZA (1) | ZA966287B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704046D0 (en) * | 1997-02-27 | 1997-04-16 | Univ Leeds | Arrestable therapeutic |
| US6897057B1 (en) | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
| CA2383372C (en) * | 1999-08-31 | 2010-04-13 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes gamma 34.5 gene expression |
| DE60115600T2 (de) | 2000-01-21 | 2006-07-20 | Biovex Ltd. | Virusstämme für die onkolytische behandlung von krebs |
| CA2352439A1 (en) * | 2001-07-17 | 2003-01-17 | Patrick W. K. Lee | Engineering oncolytic viruses |
| GB0317511D0 (en) | 2003-07-25 | 2003-08-27 | Biovex Ltd | Viral vectors |
| GB0326798D0 (en) | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
| WO2005049846A2 (en) | 2003-11-17 | 2005-06-02 | Crusade Laboratories Limited | Mutant herpes simplex virus and use thereof in the treatment of squamous cell cancer |
| US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5328688A (en) * | 1990-09-10 | 1994-07-12 | Arch Development Corporation | Recombinant herpes simplex viruses vaccines and methods |
| CA2051289C (en) * | 1990-09-14 | 2002-11-26 | Robert L. Martuza | Viral mediated destruction of neoplastic cells |
| US5585096A (en) * | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
| GB9415320D0 (en) * | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
-
1996
- 1996-07-24 ZA ZA9606287A patent/ZA966287B/xx unknown
- 1996-07-24 IL IL11894296A patent/IL118942A/en not_active IP Right Cessation
- 1996-07-25 DE DE69629819T patent/DE69629819T2/de not_active Expired - Lifetime
- 1996-07-25 WO PCT/US1996/012281 patent/WO1997004804A1/en not_active Ceased
- 1996-07-25 AT AT96927257T patent/ATE248604T1/de not_active IP Right Cessation
- 1996-07-25 AU AU67139/96A patent/AU725557B2/en not_active Expired
- 1996-07-25 EP EP96927257A patent/EP0841943B1/en not_active Expired - Lifetime
- 1996-07-25 DK DK96927257T patent/DK0841943T3/da active
- 1996-07-25 ES ES96927257T patent/ES2205053T3/es not_active Expired - Lifetime
- 1996-07-25 CA CA2227860A patent/CA2227860C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IL118942A0 (en) | 1996-10-31 |
| ES2205053T3 (es) | 2004-05-01 |
| WO1997004804A1 (en) | 1997-02-13 |
| IL118942A (en) | 2002-09-12 |
| CA2227860C (en) | 2011-05-24 |
| DE69629819T2 (de) | 2004-05-06 |
| EP0841943A1 (en) | 1998-05-20 |
| CA2227860A1 (en) | 1997-02-13 |
| DE69629819D1 (de) | 2003-10-09 |
| ZA966287B (en) | 1998-03-09 |
| AU725557B2 (en) | 2000-10-12 |
| EP0841943B1 (en) | 2003-09-03 |
| ATE248604T1 (de) | 2003-09-15 |
| AU6713996A (en) | 1997-02-26 |
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