DK0874852T3 - Antibakterielt oxazolidinonmiddel med tricykliske substituenter - Google Patents
Antibakterielt oxazolidinonmiddel med tricykliske substituenterInfo
- Publication number
- DK0874852T3 DK0874852T3 DK96939496T DK96939496T DK0874852T3 DK 0874852 T3 DK0874852 T3 DK 0874852T3 DK 96939496 T DK96939496 T DK 96939496T DK 96939496 T DK96939496 T DK 96939496T DK 0874852 T3 DK0874852 T3 DK 0874852T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibacterial oxazolidinone
- organisms
- oxazolidinone agent
- tricyclic substituents
- tricyclic
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 241000186367 Mycobacterium avium Species 0.000 abstract 2
- 241000606125 Bacteroides Species 0.000 abstract 1
- 241001112696 Clostridia Species 0.000 abstract 1
- 241000295644 Staphylococcaceae Species 0.000 abstract 1
- 241001148470 aerobic bacillus Species 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US737195P | 1995-11-17 | 1995-11-17 | |
| PCT/US1996/017120 WO1997019089A1 (en) | 1995-11-17 | 1996-11-05 | Oxazolidinone antibacterial agent with tricyclic substituents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0874852T3 true DK0874852T3 (da) | 2004-06-07 |
Family
ID=21725778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96939496T DK0874852T3 (da) | 1995-11-17 | 1996-11-05 | Antibakterielt oxazolidinonmiddel med tricykliske substituenter |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5922707A (de) |
| EP (1) | EP0874852B1 (de) |
| JP (1) | JP2000500489A (de) |
| AT (1) | ATE263172T1 (de) |
| AU (1) | AU7665196A (de) |
| DE (1) | DE69632074T2 (de) |
| DK (1) | DK0874852T3 (de) |
| ES (1) | ES2217329T3 (de) |
| PT (1) | PT874852E (de) |
| TW (1) | TW426683B (de) |
| WO (1) | WO1997019089A1 (de) |
| ZA (1) | ZA968661B (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| GB9702213D0 (en) * | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| PL338947A1 (en) * | 1997-08-15 | 2000-12-04 | Pfizer Prod Inc | Derivatives of 2-(4-aryl or heteroaryl piperazin-1-ylmethyl)-1h-indole |
| GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
| DE19802239A1 (de) * | 1998-01-22 | 1999-07-29 | Bayer Ag | Neue mit Bicyclen substituierte Oxazolidinone |
| DE19802235A1 (de) * | 1998-01-22 | 1999-07-29 | Bayer Ag | Mit tricyclischen Indolen substituierte Oxazolidinone |
| US6562844B2 (en) | 1998-01-23 | 2003-05-13 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| KR20010015910A (ko) | 1998-01-23 | 2001-02-26 | 로렌스 티. 마이젠헬더 | 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법 |
| US7002020B1 (en) | 1998-01-23 | 2006-02-21 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| DE19805117A1 (de) * | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| MY122454A (en) * | 1998-06-05 | 2006-04-29 | Upjohn Co | Use of oxazolidinones for the preparation of a medicament for transdermal delivery |
| TR200003595T2 (tr) * | 1998-06-05 | 2001-07-23 | Astrazeneca Ab | Kimyasal bileşikler |
| ES2300151T3 (es) | 1998-09-22 | 2008-06-01 | Astellas Pharma Inc. | Derivados de cianofenilo. |
| JP2002535680A (ja) | 1999-01-27 | 2002-10-22 | ファルマシア・アンド・アップジョン・カンパニー | 延長因子ｐ活性モジュレーターのアッセイ方法 |
| ES2203473T3 (es) * | 1999-05-27 | 2004-04-16 | PHARMACIA & UPJOHN COMPANY | Oxazolidinonas biciclicas como agentes antibacterianos. |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ES2258234T3 (es) | 2002-08-12 | 2006-08-16 | PHARMACIA & UPJOHN COMPANY LLC | N-aril-2-oxazolidinonas y sus derivados. |
| JP2006509035A (ja) | 2002-11-21 | 2006-03-16 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 抗菌剤としてのｎ−（４−（ピペラジン−１−イル）−フェニル−２−オキサゾリジノン−５−カルボキサミド誘導体および関連化合物 |
| CA2515311A1 (en) * | 2003-02-07 | 2004-08-19 | Warner-Lambert Company Llc | Antibacterial agents |
| EP1661898A4 (de) * | 2003-08-29 | 2009-04-15 | Takeda Pharmaceutical | Bicyclische piperazinverbindung und deren verwendung |
| AR057828A1 (es) * | 2005-09-29 | 2007-12-19 | Astrazeneca Ab | Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica |
| JP2009523820A (ja) * | 2006-01-23 | 2009-06-25 | アミラ ファーマシューティカルス，インコーポレーテッド | ５−リポキシゲナーゼの三環系抑制剤 |
| EP3553064B1 (de) * | 2016-12-12 | 2023-06-07 | Hangzhou Innogate Pharma Co., Ltd. | Verbindung mit tricyclischer heteroarylgruppe |
| CN114644634B (zh) * | 2020-12-21 | 2023-06-20 | 深圳市祥根生物医药有限公司 | 一种吡咯衍生物及其制备方法和用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883522A (en) * | 1974-02-11 | 1975-05-13 | Riker Laboratories Inc | Substituted pyrido(1,2,3-de)-1,4-benzoxazines |
| US4080499A (en) * | 1976-12-20 | 1978-03-21 | 1 | Substituted 7,8-dihydro-6H-(1,2,5)thiadiazolo(3',4'-5,6)pyrazino(2,3-b)(1,4)oxazines |
| US5039690A (en) * | 1987-10-09 | 1991-08-13 | Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents |
| AU617871B2 (en) * | 1988-09-15 | 1991-12-05 | Pharmacia & Upjohn Company | In position 3 substituted-5-beta-amidomethyl-oxazolidin-2- ones |
| US5225565A (en) * | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| JP3512110B2 (ja) * | 1992-02-13 | 2004-03-29 | ファルマシア・アンド・アップジョン・カンパニー | ベンゾジアゼピン受容体結合剤として有用な４−オキソ−および４Ｈ−イミダゾ（５，１−ｃ）（１，４）ベンゾオキサジン類 |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| US5668286A (en) * | 1994-03-15 | 1997-09-16 | Pharmacia & Upjohn Company | Oxazolidinone derivatives and pharmaceutical compositions containing them |
| BR9509673A (pt) * | 1994-11-15 | 1997-09-30 | Upjohn Co | Compostos e uso dos mesmos |
| ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
-
1996
- 1996-10-14 ZA ZA9608661A patent/ZA968661B/xx unknown
- 1996-11-05 AT AT96939496T patent/ATE263172T1/de not_active IP Right Cessation
- 1996-11-05 WO PCT/US1996/017120 patent/WO1997019089A1/en not_active Ceased
- 1996-11-05 AU AU76651/96A patent/AU7665196A/en not_active Abandoned
- 1996-11-05 DK DK96939496T patent/DK0874852T3/da active
- 1996-11-05 JP JP9519726A patent/JP2000500489A/ja not_active Withdrawn
- 1996-11-05 ES ES96939496T patent/ES2217329T3/es not_active Expired - Lifetime
- 1996-11-05 EP EP96939496A patent/EP0874852B1/de not_active Expired - Lifetime
- 1996-11-05 DE DE69632074T patent/DE69632074T2/de not_active Expired - Fee Related
- 1996-11-05 PT PT96939496T patent/PT874852E/pt unknown
- 1996-11-15 TW TW085114048A patent/TW426683B/zh not_active IP Right Cessation
-
1997
- 1997-05-02 US US08/850,424 patent/US5922707A/en not_active Expired - Fee Related
-
1999
- 1999-02-15 US US09/250,382 patent/US5955460A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997019089A1 (en) | 1997-05-29 |
| JP2000500489A (ja) | 2000-01-18 |
| ZA968661B (en) | 1998-04-14 |
| EP0874852B1 (de) | 2004-03-31 |
| DE69632074T2 (de) | 2005-01-20 |
| ES2217329T3 (es) | 2004-11-01 |
| DE69632074D1 (de) | 2004-05-06 |
| US5955460A (en) | 1999-09-21 |
| ATE263172T1 (de) | 2004-04-15 |
| US5922707A (en) | 1999-07-13 |
| TW426683B (en) | 2001-03-21 |
| AU7665196A (en) | 1997-06-11 |
| PT874852E (pt) | 2004-08-31 |
| EP0874852A1 (de) | 1998-11-04 |
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