DK1129110T3 - Blodpladeafledt vækstfaktor D, DNA kodende derfor og anvendelser deraf - Google Patents

Blodpladeafledt vækstfaktor D, DNA kodende derfor og anvendelser deraf

Info

Publication number
DK1129110T3
DK1129110T3 DK99958854.4T DK99958854T DK1129110T3 DK 1129110 T3 DK1129110 T3 DK 1129110T3 DK 99958854 T DK99958854 T DK 99958854T DK 1129110 T3 DK1129110 T3 DK 1129110T3
Authority
DK
Denmark
Prior art keywords
platelet
growth factor
derived growth
dna coding
pdgf
Prior art date
Application number
DK99958854.4T
Other languages
English (en)
Inventor
Ulf Eriksson
Karin Aase
Annica Ponten
Marko Uutela
Kari Alitalo
Arne Oestman
Carl-Henrik Heldin
Xuri Li
Original Assignee
Ludwig Inst Cancer Res
Licentia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res, Licentia Ltd filed Critical Ludwig Inst Cancer Res
Application granted granted Critical
Publication of DK1129110T3 publication Critical patent/DK1129110T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
DK99958854.4T 1998-11-10 1999-11-10 Blodpladeafledt vækstfaktor D, DNA kodende derfor og anvendelser deraf DK1129110T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10785298P 1998-11-10 1998-11-10
US11399798P 1998-12-28 1998-12-28
US15060499P 1999-08-26 1999-08-26
US15710899P 1999-10-04 1999-10-04
US15775699P 1999-10-05 1999-10-05
PCT/US1999/026462 WO2000027879A1 (en) 1998-11-10 1999-11-10 Platelet-derived growth factor d, dna coding therefor, and uses thereof

Publications (1)

Publication Number Publication Date
DK1129110T3 true DK1129110T3 (da) 2010-04-06

Family

ID=27537197

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99958854.4T DK1129110T3 (da) 1998-11-10 1999-11-10 Blodpladeafledt vækstfaktor D, DNA kodende derfor og anvendelser deraf

Country Status (12)

Country Link
US (1) US6706687B1 (da)
EP (2) EP1129110B1 (da)
JP (1) JP2002534061A (da)
CN (1) CN1261453C (da)
AT (2) ATE451389T1 (da)
AU (1) AU770899B2 (da)
CA (1) CA2349951A1 (da)
DE (1) DE69941791D1 (da)
DK (1) DK1129110T3 (da)
ES (1) ES2336731T3 (da)
NZ (1) NZ511379A (da)
WO (1) WO2000027879A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630142B2 (en) * 1999-05-03 2003-10-07 Zymogenetics, Inc. Method of treating fibroproliferative disorders
US6468543B1 (en) 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
WO2000066736A1 (en) * 1999-05-03 2000-11-09 Zymogenetics, Inc. Growth factor homolog zvegf4
CA2386383A1 (en) * 1999-10-07 2001-04-12 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
AU2001272902A1 (en) * 2000-05-19 2001-12-03 Eli Lilly And Company Treating musculoskeletal disorders using lp85 and analogs thereof
AU2002248237A1 (en) 2000-10-30 2002-08-12 Zymogenetics, Inc. Compositions and methods for improving kidney function
AU2002248201A1 (en) * 2000-11-16 2002-08-06 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
ES2302845T3 (es) * 2001-10-19 2008-08-01 Zymogenetics, Inc. Factor de crecimiento dimerizado y materiales y metodos para producirlo.
US7135174B2 (en) * 2002-01-07 2006-11-14 Amgen Fremont, Inc. Antibodies directed to PDGFD and uses thereof
AU2003210996A1 (en) * 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
CA2499207A1 (en) * 2002-09-16 2004-03-25 Abgenix, Inc. Method for the treatment of nephritis using anti-pdgf-dd antibodies
US20030100502A1 (en) * 2002-10-23 2003-05-29 Beals John Michael Treating musculoskeletal disorders using lp85 and analogs thereof
US20050191286A1 (en) * 2004-02-09 2005-09-01 Gandy James B. Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
WO2005086684A2 (en) * 2004-03-08 2005-09-22 Ludwig Institute For Cancer Research Method for modulating, regulating and/or stabilizing angiogenesis
US20060004189A1 (en) * 2004-07-02 2006-01-05 James Gandy Compositions for treating wounds and processes for their preparation
US20060142198A1 (en) * 2004-07-02 2006-06-29 Wound Care Partners Llc Compositions for treating wounds and processes for their preparation
US20090041755A1 (en) * 2005-05-10 2009-02-12 Ludwig Institute For Cancer Research Methods and Compositions For PDGF-D Activation and Inhibition
EP1919944B1 (en) 2005-08-15 2011-03-23 Vegenics Pty Ltd Modified vegf and pdgf with improved angiogenic properties
AU2007254243B2 (en) 2006-05-17 2013-06-13 Ludwig Institute For Cancer Research Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases
CA2751445C (en) 2009-02-06 2018-06-19 Pepscan Systems B.V. Truncated cystine-knot proteins
KR101451340B1 (ko) * 2012-08-02 2014-10-15 (주)애드바이오텍 모발 생장 촉진용 조성물
CN103469672A (zh) * 2013-09-07 2013-12-25 郴州四方立投资有限公司 一种用于造纸行业的硅灰石长纤维的制备方法
EP3322297B1 (en) * 2015-07-13 2024-12-04 Sangamo Therapeutics, Inc. Delivery methods and compositions for nuclease-mediated genome engineering
CN110590930B (zh) * 2018-06-13 2023-03-31 四川好医生攀西药业有限责任公司 美洲大蠊生长因子pdgf在制备损伤修复药物中的应用
CN111487398B (zh) * 2019-01-25 2022-11-11 四川大学华西医院 血管瘤治疗的生物标记物
CN115612661B (zh) * 2021-07-14 2026-02-13 中山大学中山眼科中心 Pdgf-d在调控干细胞增殖和/或分化中的应用
CN114957439B (zh) * 2022-05-31 2023-11-28 新疆畜牧科学院生物技术研究所（新疆畜牧科学院中国-澳大利亚绵羊育种研究中心） 绵羊pdgfd、编码pdgfd核酸及其重组慢病毒、宿主细胞与应用
CN119997965A (zh) * 2022-06-29 2025-05-13 天津大学 Pdgf-d前结构域及其变体和融合体
KR20250040765A (ko) * 2023-09-15 2025-03-25 (주)케어젠 펩타이드를 유효성분으로 하는 발모 촉진 또는 탈모증의 억제, 예방 또는 개선용 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
US5585277A (en) 1993-06-21 1996-12-17 Scriptgen Pharmaceuticals, Inc. Screening method for identifying ligands for target proteins
ES2249762T3 (es) 1994-03-08 2006-04-01 Human Genome Sciences, Inc. Factor de crecimiento del endotelio vascular 2.
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
US5607918A (en) 1995-03-01 1997-03-04 Ludwig Institute For Cancer Research Vascular endothelial growth factor-B and DNA coding therefor
NZ301611A (en) 1995-03-02 2000-02-28 Amrad Operations Pty Ltd a peptide having vascular endothelial growth factor like properties, nucleic acid molecule encoding it and its use
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
WO1998007832A1 (en) 1996-08-23 1998-02-26 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor d (vegf-d)
AU764039B2 (en) * 1998-12-07 2003-08-07 Zymogenetics Inc. Growth factor homolog ZVEGF3
WO2000066736A1 (en) * 1999-05-03 2000-11-09 Zymogenetics, Inc. Growth factor homolog zvegf4

Also Published As

Publication number Publication date
EP1129110B1 (en) 2009-12-09
EP1129110A4 (en) 2004-08-04
AU1613600A (en) 2000-05-29
ATE556090T1 (de) 2012-05-15
ATE451389T1 (de) 2009-12-15
CN1325407A (zh) 2001-12-05
EP2151454A3 (en) 2010-02-17
US6706687B1 (en) 2004-03-16
EP2151454A2 (en) 2010-02-10
WO2000027879A1 (en) 2000-05-18
DE69941791D1 (de) 2010-01-21
JP2002534061A (ja) 2002-10-15
EP1129110A1 (en) 2001-09-05
CN1261453C (zh) 2006-06-28
CA2349951A1 (en) 2000-05-18
NZ511379A (en) 2003-06-30
AU770899B2 (en) 2004-03-04
EP2151454B1 (en) 2012-05-02
ES2336731T3 (es) 2010-04-15

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