DK1295944T3 - GDP-dissociationsstimulerende protein, hjernespecifikt nukleosomsamlingsprotein, skeletmuskelspecifikt ubiquitinkonjugerende enzym, celleproliferationsprotein, phosphatidylinositolkinase, nelbeslægtede proteiner - Google Patents
GDP-dissociationsstimulerende protein, hjernespecifikt nukleosomsamlingsprotein, skeletmuskelspecifikt ubiquitinkonjugerende enzym, celleproliferationsprotein, phosphatidylinositolkinase, nelbeslægtede proteinerInfo
- Publication number
- DK1295944T3 DK1295944T3 DK02026841T DK02026841T DK1295944T3 DK 1295944 T3 DK1295944 T3 DK 1295944T3 DK 02026841 T DK02026841 T DK 02026841T DK 02026841 T DK02026841 T DK 02026841T DK 1295944 T3 DK1295944 T3 DK 1295944T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- specific
- nel
- brain
- cell proliferation
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 102000004169 proteins and genes Human genes 0.000 title 3
- 101710107897 Nucleosome assembly protein Proteins 0.000 title 1
- 102000017343 Phosphatidylinositol kinases Human genes 0.000 title 1
- 108050005377 Phosphatidylinositol kinases Proteins 0.000 title 1
- 101100133168 Rattus norvegicus Nell2 gene Proteins 0.000 title 1
- 102000003431 Ubiquitin-Conjugating Enzyme Human genes 0.000 title 1
- 108060008747 Ubiquitin-Conjugating Enzyme Proteins 0.000 title 1
- 210000004556 brain Anatomy 0.000 title 1
- 230000004663 cell proliferation Effects 0.000 title 1
- 210000002027 skeletal muscle Anatomy 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102000003839 Human Proteins Human genes 0.000 abstract 1
- 108090000144 Human Proteins Proteins 0.000 abstract 1
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 208000024556 Mendelian disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6341096 | 1996-03-19 | ||
| JP06916397A JP3646191B2 (ja) | 1996-03-19 | 1997-03-05 | ヒト遺伝子 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1295944T3 true DK1295944T3 (da) | 2007-09-17 |
Family
ID=26404531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02026841T DK1295944T3 (da) | 1996-03-19 | 1997-03-19 | GDP-dissociationsstimulerende protein, hjernespecifikt nukleosomsamlingsprotein, skeletmuskelspecifikt ubiquitinkonjugerende enzym, celleproliferationsprotein, phosphatidylinositolkinase, nelbeslægtede proteiner |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US5831058A (fr) |
| EP (6) | EP1295944B1 (fr) |
| JP (1) | JP3646191B2 (fr) |
| AT (1) | ATE362536T1 (fr) |
| CA (2) | CA2200371C (fr) |
| DE (1) | DE69737740T2 (fr) |
| DK (1) | DK1295944T3 (fr) |
| ES (1) | ES2284770T3 (fr) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US20030170864A1 (en) * | 2000-05-30 | 2003-09-11 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2274732A1 (fr) * | 1996-12-18 | 1998-06-25 | Genetics Institute, Inc. | Proteines secretees et polynucleotides codant pour lesdites proteines |
| US5976837A (en) * | 1997-03-14 | 1999-11-02 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US5863779A (en) * | 1997-08-21 | 1999-01-26 | Incyte Pharmaceuticals, Inc. | UBC7-like ubiquitin-conjugating enzyme |
| WO1999050421A1 (fr) * | 1998-03-27 | 1999-10-07 | University Of Leeds | Enzyme conjuguant l'ubiquitine |
| US6171790B1 (en) | 1998-05-01 | 2001-01-09 | Incyte Pharmaceuticals, Inc. | Human protease associated proteins |
| JP2000109433A (ja) * | 1998-08-05 | 2000-04-18 | Otsuka Pharmaceut Co Ltd | 神経変性疾患治療剤 |
| AU4649600A (en) * | 1999-04-22 | 2000-11-10 | Joel F. Habener | Bridge-1, a transcription factor |
| US7884066B2 (en) * | 1999-10-05 | 2011-02-08 | The Regents Of The University Of California | NELL-1 enhanced bone mineralization |
| AU2001240820A1 (en) * | 2000-03-15 | 2001-09-24 | Oxford Glycosciences (Uk) Ltd. | Proteins, genes and their use for diagnosis and treatment of vascular dementia |
| US6689877B2 (en) * | 2000-11-06 | 2004-02-10 | The Board Of Regents Of The University Of Nebraska | Methods and compositions for the treatment of human immunodeficiency virus infection |
| US20030039968A1 (en) * | 2001-07-10 | 2003-02-27 | Applera Corporation | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
| US20040049024A1 (en) * | 2001-12-07 | 2004-03-11 | Geoff Clark | Compositions and methods related to the minn1 tumor suppressor gene and protein |
| AU2003299314A1 (en) | 2002-12-16 | 2004-07-09 | Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung | Fwd, pp2c1, adk3, cg3860, cdk4, cg7134, eip75b involved in the regulation of energy homeostasis |
| DE602004032107D1 (de) | 2003-02-07 | 2011-05-19 | Univ California | Nell-peptidexpressionssysteme und knochenbildende aktivität des nell-peptids |
| US7691607B2 (en) | 2004-02-09 | 2010-04-06 | The Regents Of The University Of California | Expression system of NELL peptide |
| KR20120064120A (ko) | 2004-06-01 | 2012-06-18 | 제넨테크, 인크. | 항체 약물 접합체 및 방법 |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| EP1817059A2 (fr) | 2004-12-01 | 2007-08-15 | Genentech, Inc. | Conjugues medicament anticorps et procedes correspondants |
| MX2010003718A (es) * | 2007-10-19 | 2010-04-21 | Genentech Inc | Anticuerpos anti-tenb2 producidos por ingenieria de cisteina y conjugados de farmaco y anticuerpo. |
| CA2739608A1 (fr) * | 2008-10-07 | 2010-04-15 | The Regents Of The University Of California | Production de proteines nell recombinantes |
| CA2809819A1 (fr) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Conjugues medicamenteux cibles a visee extracellulaire |
| DK2528625T3 (da) | 2010-04-15 | 2013-10-14 | Spirogen Sarl | Pyrrolobenzodiazepiner og konjugater deraf |
| BR112012030311A2 (pt) | 2010-06-08 | 2017-01-24 | Genentech Inc | anticorpo |
| JP5889912B2 (ja) | 2010-11-17 | 2016-03-22 | ジェネンテック， インコーポレイテッド | アラニニルメイタンシノール抗体コンジュゲート |
| KR101992502B1 (ko) | 2011-05-12 | 2019-06-24 | 제넨테크, 인크. | 프레임워크 시그너처 펩티드를 사용하여 동물 샘플에서 치료 항체를 검출하기 위한 다중 반응 모니터링 lc-ms/ms 방법 |
| JP6104257B2 (ja) | 2011-10-14 | 2017-03-29 | メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ | ピロロベンゾジアゼピンおよびそのコンジュゲート |
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| CN104837502B (zh) | 2012-10-12 | 2018-08-10 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓及其结合物 |
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| EP4698230A2 (fr) | 2023-04-17 | 2026-02-25 | Peak Bio, Inc. | Anticorps et conjugués anticorps-médicament et procédés d'utilisation, processus synthétiques et intermédiaires |
| WO2026006688A2 (fr) | 2024-06-28 | 2026-01-02 | Firefly Bio, Inc. | Conjugués d'anticorps de dégradation et leurs utilisations |
| WO2026006689A2 (fr) | 2024-06-28 | 2026-01-02 | Firefly Bio, Inc. | Conjugués anticorps-dégradeur de bcl-xl et leurs utilisations |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05268957A (ja) | 1992-03-27 | 1993-10-19 | Bio Material Kenkyusho:Kk | ラット多機能プロテアーゼ構成因子およびそのｄｎａ |
| JP3125235B2 (ja) | 1992-04-22 | 2001-01-15 | 株式会社バイオマテリアル研究所 | ヒト２６ｓプロテアソーム |
| JPH05317059A (ja) | 1992-05-22 | 1993-12-03 | Bio Material Kenkyusho:Kk | ラットプロテアソームのコンポーネントおよび そのｄｎａ |
| US5470577A (en) * | 1993-07-07 | 1995-11-28 | Trustees Of Boston University | Stimulation of tanning by DNA fragments or single-stranded DNA |
| AU713364B2 (en) * | 1995-05-19 | 1999-12-02 | Human Genome Sciences, Inc. | Transforming growth factor alpha HII |
| US5863779A (en) * | 1997-08-21 | 1999-01-26 | Incyte Pharmaceuticals, Inc. | UBC7-like ubiquitin-conjugating enzyme |
| DE602004032107D1 (de) * | 2003-02-07 | 2011-05-19 | Univ California | Nell-peptidexpressionssysteme und knochenbildende aktivität des nell-peptids |
-
1997
- 1997-03-05 JP JP06916397A patent/JP3646191B2/ja not_active Expired - Fee Related
- 1997-03-19 EP EP02026841A patent/EP1295944B1/fr not_active Expired - Lifetime
- 1997-03-19 DK DK02026841T patent/DK1295944T3/da active
- 1997-03-19 ES ES02026841T patent/ES2284770T3/es not_active Expired - Lifetime
- 1997-03-19 CA CA002200371A patent/CA2200371C/fr not_active Expired - Fee Related
- 1997-03-19 AT AT02026841T patent/ATE362536T1/de active
- 1997-03-19 EP EP10185775A patent/EP2361982A1/fr not_active Withdrawn
- 1997-03-19 EP EP97104842A patent/EP0796913A3/fr not_active Ceased
- 1997-03-19 DE DE69737740T patent/DE69737740T2/de not_active Expired - Lifetime
- 1997-03-19 CA CA2641565A patent/CA2641565C/fr not_active Expired - Fee Related
- 1997-03-19 EP EP10182760A patent/EP2272960A1/fr not_active Withdrawn
- 1997-03-19 EP EP07014998A patent/EP1860189A1/fr not_active Withdrawn
- 1997-03-19 EP EP04004141A patent/EP1439230A3/fr not_active Withdrawn
- 1997-03-19 US US08/820,170 patent/US5831058A/en not_active Expired - Lifetime
-
2004
- 2004-02-20 US US10/781,841 patent/US20060134634A1/en not_active Abandoned
-
2006
- 2006-11-07 US US11/593,525 patent/US7674889B2/en not_active Expired - Fee Related
-
2007
- 2007-07-06 US US11/774,330 patent/US7592438B2/en not_active Expired - Fee Related
-
2009
- 2009-07-27 US US12/510,074 patent/US7858754B2/en not_active Expired - Fee Related
-
2010
- 2010-01-19 US US12/689,917 patent/US8048995B2/en not_active Expired - Fee Related
- 2010-12-23 US US12/977,497 patent/US8106171B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7858754B2 (en) | 2010-12-28 |
| US20100160611A1 (en) | 2010-06-24 |
| US8048995B2 (en) | 2011-11-01 |
| JP3646191B2 (ja) | 2005-05-11 |
| CA2200371A1 (fr) | 1997-09-19 |
| ES2284770T3 (es) | 2007-11-16 |
| US7592438B2 (en) | 2009-09-22 |
| CA2641565A1 (fr) | 1997-09-19 |
| EP1439230A3 (fr) | 2004-09-22 |
| DE69737740D1 (de) | 2007-06-28 |
| JPH09308492A (ja) | 1997-12-02 |
| EP1295944B1 (fr) | 2007-05-16 |
| CA2200371C (fr) | 2007-07-10 |
| EP2361982A1 (fr) | 2011-08-31 |
| US20060134634A1 (en) | 2006-06-22 |
| US20080032337A1 (en) | 2008-02-07 |
| DE69737740T2 (de) | 2008-01-31 |
| US20110105718A1 (en) | 2011-05-05 |
| ATE362536T1 (de) | 2007-06-15 |
| US5831058A (en) | 1998-11-03 |
| EP1860189A1 (fr) | 2007-11-28 |
| CA2641565C (fr) | 2012-11-13 |
| US20070111285A1 (en) | 2007-05-17 |
| EP1295944A2 (fr) | 2003-03-26 |
| EP0796913A3 (fr) | 2001-01-31 |
| US8106171B2 (en) | 2012-01-31 |
| EP1295944A3 (fr) | 2004-04-21 |
| US7674889B2 (en) | 2010-03-09 |
| US20100048878A1 (en) | 2010-02-25 |
| EP1439230A2 (fr) | 2004-07-21 |
| EP0796913A2 (fr) | 1997-09-24 |
| EP2272960A1 (fr) | 2011-01-12 |
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