DK1311682T3 - Rekombinante konstruktioner af Borrelia burgdorferi - Google Patents

Rekombinante konstruktioner af Borrelia burgdorferi

Info

Publication number: DK1311682T3
Authority: DK; Denmark
Prior art keywords: chimeric; borrelia burgdorferi; recombinant constructs; disclosed; proteins
Prior art date: 2000-08-18

Application number

DK01959607T

Other languages

English (en)

Inventor

Benjamin J Luft

John J Dunn

Original Assignee

Univ New York State Res Found

Brookhaven Sciences Ass Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-18

Filing date

2001-08-07

Publication date

2008-05-05

2001-08-07 Application filed by Univ New York State Res Found, Brookhaven Sciences Ass Llc filed Critical Univ New York State Res Found

2008-05-05 Application granted granted Critical

2008-05-05 Publication of DK1311682T3 publication Critical patent/DK1311682T3/da

Links

241000589969 Borreliella burgdorferi Species 0.000 title 1
208000016604 Lyme disease Diseases 0.000 abstract 2
230000000890 antigenic effect Effects 0.000 abstract 2
239000012634 fragment Substances 0.000 abstract 2
102000037865 fusion proteins Human genes 0.000 abstract 2
108020001507 fusion proteins Proteins 0.000 abstract 2
150000007523 nucleic acids Chemical class 0.000 abstract 2
241000589968 Borrelia Species 0.000 abstract 1
108700006640 OspA Proteins 0.000 abstract 1
108700023315 OspC Proteins 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK01959607T 2000-08-18 2001-08-07 Rekombinante konstruktioner af Borrelia burgdorferi DK1311682T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US22648400P	2000-08-18	2000-08-18
US66601700A	2000-09-19	2000-09-19
PCT/US2001/024736 WO2002016422A2 (en)	2000-08-18	2001-08-07	Recombinant constructs of borrelia burgdorferi

Publications (1)

Publication Number	Publication Date
DK1311682T3 true DK1311682T3 (da)	2008-05-05

Family

ID=26920578

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01959607T DK1311682T3 (da)	2000-08-18	2001-08-07	Rekombinante konstruktioner af Borrelia burgdorferi

Country Status (8)

Country	Link
EP (1)	EP1311682B1 (da)
AT (1)	ATE380870T1 (da)
AU (1)	AU2001281145A1 (da)
DE (1)	DE60131858T2 (da)
DK (1)	DK1311682T3 (da)
ES (1)	ES2298246T3 (da)
PT (1)	PT1311682E (da)
WO (1)	WO2002016422A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7008625B2 (en)	1993-11-01	2006-03-07	Research Foundation Of The State University Of New York	Recombinant constructs of Borrelia burgdorferi
US8821893B2 (en)	2004-07-02	2014-09-02	Bio Peptides, Corp.	Oral vaccine for Borrelia
AU2007295927A1 (en)	2006-09-15	2008-03-20	Intercell Ag	Borrelia antigens
CA2668100C (en) *	2006-11-01	2014-12-23	Immport Therapeutics, Inc.	Compositions and methods for immunodominant antigens
EP2361930A3 (en)	2007-03-26	2011-10-26	Dako Denmark A/S	Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
EP3620465B1 (en)	2007-07-03	2025-02-19	Dako Denmark A/S	Improved methods for generation, labeling and use of mhc multimers
US10611818B2 (en)	2007-09-27	2020-04-07	Agilent Technologies, Inc.	MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da)	2008-02-28	2019-09-09	Dako Denmark As	MHC-multimerer til Borrelia-diagnostik og sygdom
US10722562B2 (en)	2008-07-23	2020-07-28	Immudex Aps	Combinatorial analysis and repair
GB0817244D0 (en)	2008-09-20	2008-10-29	Univ Cardiff	Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (en)	2008-10-02	2010-04-08	Dako Denmark A/S	Molecular vaccines for infectious disease
US11992518B2 (en)	2008-10-02	2024-05-28	Agilent Technologies, Inc.	Molecular vaccines for infectious disease
WO2011081598A1 (en) *	2009-12-28	2011-07-07	Mivac Development Aktiebolag	New antigens for use in a vaccine against h.pylori infection
EP3705133B1 (en)	2010-05-14	2024-06-26	Baxalta Incorporated	Ospa chimeras and use thereof in vaccines
JP2015524802A (ja)	2012-07-27	2015-08-27	バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒＩｎｔｅｒｎａｔｉｏｎａｌＩｎｃｏｒｐ０Ｒａｔｅｄ	キメラｏｓｐａ分子を含む組成物およびその使用方法
PL223175B1 (pl)	2012-10-22	2016-10-31	Inst Chemii Bioorganicznej Polskiej Akademii Nauk	Szczepionka przeciw boreliozie, konstrukt genetyczny, rekombinowane białko, sposób otrzymywania konstruktu genetycznego, sposób otrzymywania szczepionki, sposób otrzymywania rekombinowanych białek, zastosowanie rekombinowanych białek do wytwarzania szczepionki przeciwko boreliozie
CZ2014320A3 (cs) *	2014-05-09	2015-11-18	VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i.	Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy
HK1244534A1 (zh) *	2014-10-07	2018-08-10	The Research Foundation For The State University Of New York	重组疏螺旋体蛋白及其使用方法
US12258373B2 (en)	2018-12-17	2025-03-25	Immudex Aps	Panel comprising Borrelia MHC multimers
WO2025015077A1 (en) *	2023-07-10	2025-01-16	Dynavax Technologies Corporation	Lyme disease vaccines comprising an adjuvant and borrelia outer surface protein a and c antigens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT726955E (pt) *	1993-11-01	2004-08-31	Brookhaven Science Ass Llc	Proteinas quimericas compreendendo polipeptidos borrelia: suas utilizacoes
PT1100922E (pt) *	1998-07-31	2008-05-30	Gundersen Lutheran Medical Fou	Utilização do(s) epítopo(s) borrelicida(s) da proteína de superfície externa c (ospc) de borrelia burgdorferi, como vacina

2001
- 2001-08-07 DK DK01959607T patent/DK1311682T3/da active
- 2001-08-07 EP EP01959607A patent/EP1311682B1/en not_active Expired - Lifetime
- 2001-08-07 AU AU2001281145A patent/AU2001281145A1/en not_active Abandoned
- 2001-08-07 AT AT01959607T patent/ATE380870T1/de active
- 2001-08-07 DE DE60131858T patent/DE60131858T2/de not_active Expired - Lifetime
- 2001-08-07 WO PCT/US2001/024736 patent/WO2002016422A2/en not_active Ceased
- 2001-08-07 ES ES01959607T patent/ES2298246T3/es not_active Expired - Lifetime
- 2001-08-07 PT PT01959607T patent/PT1311682E/pt unknown

Also Published As

Publication number	Publication date
WO2002016422A2 (en)	2002-02-28
DE60131858D1 (de)	2008-01-24
AU2001281145A1 (en)	2002-03-04
PT1311682E (pt)	2008-03-11
EP1311682B1 (en)	2007-12-12
ATE380870T1 (de)	2007-12-15
DE60131858T2 (de)	2008-12-04
EP1311682A2 (en)	2003-05-21
ES2298246T3 (es)	2008-05-16
WO2002016422A3 (en)	2002-10-03

Publication	Publication Date	Title
DK1311682T3 (da)	2008-05-05	Rekombinante konstruktioner af Borrelia burgdorferi
DK0726955T3 (da)	2004-08-09	Kimære proteiner, som omfatter Borreliapolypeptider, og anvendelser heraf
PL351277A1 (en)	2002-07-01	Nucleic acid sequence, dna fragments, recombined dna molecules, live recombined carriers, host cells, proteins and their application, vaccines against lawsonia intracellularis and methods of obtaining them as well as relevant diagnostic tests
CY1118443T1 (el)	2017-06-28	Anti-tnf αντισωματα, συνθεσεις, μεθοδοι και χρησεις
DK1282702T3 (da)	2007-04-02	Immunogene polypeptider, som er kodet af KAGE-minigener, og anvendelser deraf
EP1609107A4 (en)	2006-08-30	METHOD FOR IDENTIFYING OPTIMAL PEPTIDE PITOPARIANTS
DE60139542D1 (de)	2009-09-24	Methoden zur herstellung humaner monoklonaler antikörper
DK0870046T3 (da)	2009-05-11	Levende rekombinant vaccine som indeholder felint herpesvirus type 1, især til behandling af felin infektiös peritonitis
NO20054836L (no)	2005-10-19	Nogo-reseptorbindingsprotein
ATE470673T1 (de)	2010-06-15	Impfstoffe mit lawsoniaintrazellularis- untereinheit
WO2004098526A3 (en)	2005-05-19	Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein
WO2003058248A3 (en)	2003-12-18	Diagnostics and vaccines for mycrobacterium paratuberculosis infections
DK1053329T3 (da)	2010-01-25	Rekombinant lipideret PsaA-protein, fremgangsmåder til fremstilling og anvendelse
DK1386931T3 (da)	2006-09-04	Human neurotriminhomolog
ATE450545T1 (de)	2009-12-15	Impfstoff mit lawsonia intracellularis- untereinheit
WO2004007726A3 (en)	2004-02-19	Brachyspira hyodysenteriae vaccine
WO2005002512A3 (en)	2005-04-14	Immunotherapeutic vaccine strategy
DK1078072T3 (da)	2007-05-14	Nye peptidfragmenter til oprensning af proteiner
WO1999042586A3 (en)	2000-02-24	Exo1 and exo2, exocytotic proteins
PT1176192E (pt)	2004-01-30	Vacina de helicobacter felis
AR030133A1 (es)	2003-08-13	Anticuerpos anti-tnf, composiciones, metodos y usos
ECSP993160A (es)	2000-01-27	Acidos nucleicos y polipeptidos homologos il-17, vectores,celulas huesped, metodos y usos de los mismos