DK1480981T3 - 1-(Alkyl)-, 1-(heteroaryl)alkyl- og 1-[(aryl)alkyl]-7-(pyrimidin-4-yl) imidazo[1,2a]pyrimidin-5(1H)-onderivater - Google Patents

1-(Alkyl)-, 1-(heteroaryl)alkyl- og 1-[(aryl)alkyl]-7-(pyrimidin-4-yl) imidazo[1,2a]pyrimidin-5(1H)-onderivater

Info

Publication number: DK1480981T3
Authority: DK; Denmark
Prior art keywords: alkyl; pyrimidin; imidazo; heteroaryl; aryl
Prior art date: 2002-02-28

Application number

DK03709786T

Other languages

Danish (da)

English (en)

Inventor

Alistair Lochead

Philippe Yaiche

Mourad Saady

Original Assignee

Sanofi Aventis

Mitsubishi Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-28

Filing date

2003-02-26

Publication date

2006-03-20

2003-02-26 Application filed by Sanofi Aventis, Mitsubishi Pharma Corp filed Critical Sanofi Aventis

2006-03-20 Application granted granted Critical

2006-03-20 Publication of DK1480981T3 publication Critical patent/DK1480981T3/da

Links

125000000217 alkyl group Chemical group 0.000 title 3
UUHMFGQYTIQQIS-UHFFFAOYSA-N 1h-imidazo[1,2-a]pyrimidin-5-one Chemical class O=C1C=CN=C2NC=CN12 UUHMFGQYTIQQIS-UHFFFAOYSA-N 0.000 title 1
125000003118 aryl group Chemical group 0.000 title 1
125000001072 heteroaryl group Chemical group 0.000 title 1
125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Oncology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK03709786T 2002-02-28 2003-02-26 1-(Alkyl)-, 1-(heteroaryl)alkyl- og 1-[(aryl)alkyl]-7-(pyrimidin-4-yl) imidazo[1,2a]pyrimidin-5(1H)-onderivater DK1480981T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02290487A EP1340759A1 (fr)	2002-02-28	2002-02-28	Dérivés de la 1-alkyl, 1-(hétéroalkyl)alkyl et 1-(aryl)alkyl-7-pyrimidin-4-ylimidazo[1,2-a]pyrimidin-5(1H)-one

Publications (1)

Publication Number	Publication Date
DK1480981T3 true DK1480981T3 (da)	2006-03-20

Family

ID=27675771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03709786T DK1480981T3 (da)	2002-02-28	2003-02-26	1-(Alkyl)-, 1-(heteroaryl)alkyl- og 1-[(aryl)alkyl]-7-(pyrimidin-4-yl) imidazo[1,2a]pyrimidin-5(1H)-onderivater

Country Status (23)

Country	Link
US (2)	US7429663B2 (fr)
EP (2)	EP1340759A1 (fr)
JP (1)	JP4484524B2 (fr)
KR (1)	KR100935262B1 (fr)
CN (1)	CN100441581C (fr)
AR (1)	AR038620A1 (fr)
AT (1)	ATE309246T1 (fr)
AU (1)	AU2003214127C1 (fr)
BR (1)	BR0308106A (fr)
CA (1)	CA2474875C (fr)
DE (1)	DE60302220T2 (fr)
DK (1)	DK1480981T3 (fr)
EA (1)	EA007459B1 (fr)
ES (1)	ES2250876T3 (fr)
IL (1)	IL163288A (fr)
MX (1)	MXPA04008365A (fr)
NO (1)	NO329756B1 (fr)
NZ (1)	NZ534467A (fr)
PL (1)	PL372664A1 (fr)
SI (1)	SI1480981T1 (fr)
TW (1)	TWI305534B (fr)
WO (1)	WO2003072580A1 (fr)
ZA (1)	ZA200406154B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2541832C (fr) *	2003-10-10	2009-11-24	Pfizer Products Inc.	2h-[1,2,4]triazolo[4,3-a]pyrazines substituees en tant qu'inhibiteurs de la gsk-3
EP2258358A3 (fr)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenèse avec un inhibiteur de l'acetylcholinestérase
EP1928437A2 (fr)	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenese par modulation du recepteur muscarinique
EP1940389A2 (fr)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation de la neurogenese par inhibition de la pde
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
AU2009260526A1 (en) *	2008-05-30	2009-12-23	Merck Sharp & Dohme Corp.	Novel substituted indoles
EP2138494A1 (fr) *	2008-06-26	2009-12-30	Sanofi-Aventis	Dérivés substitués d'alkyl pyrimidin-4-one
WO2010099217A1 (fr)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
ES2627428T3 (es) *	2009-07-02	2017-07-28	Sanofi	Nuevos derivados de 2,3-dihidro-1H-imidazo{1,2-a}pirimidin-5-ona, su preparación y su utilización farmacéutica
RS61810B1 (sr) *	2014-05-13	2021-06-30	Hoffmann La Roche	Deuterisana heterociklična jedinjenja i njihova upotreba kao sredstva za snimanje
CN112574219A (zh) *	2021-01-31	2021-03-30	湖北大学	一种苯并咪唑并嘧啶酮衍生物的合成方法
CN115448921B (zh) *	2021-06-08	2023-08-01	四川大学	一类咪唑烷并嘧啶酮化合物及在治疗HsClpP介导的疾病中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3571974D1 (en) *	1984-12-06	1989-09-07	Pfizer	Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them
AU733877C (en) *	1996-12-05	2003-05-08	Amgen, Inc.	Substituted pyrimidine compounds and their use
TWI241298B (en) *	1998-09-25	2005-10-11	Mitsubishi Chem Corp	Pyrimidone derivatives
EP1184384A1 (fr) *	2000-09-01	2002-03-06	Sanofi-Synthelabo	Dérivés du 1-alkyl, 1-(hétéroalkyl)alkyl et 1-(aryl)alkyl-7-pyridin-4-ylimidazo[1,2-a]pyrimidin-5(1H)-one
EP1295884A1 (fr) *	2001-09-21	2003-03-26	Sanofi-Synthelabo	Dérivés de 2-Pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-Pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one

2002
- 2002-02-28 EP EP02290487A patent/EP1340759A1/fr not_active Withdrawn
2003
- 2003-02-26 ES ES03709786T patent/ES2250876T3/es not_active Expired - Lifetime
- 2003-02-26 EA EA200400937A patent/EA007459B1/ru not_active IP Right Cessation
- 2003-02-26 CA CA2474875A patent/CA2474875C/fr not_active Expired - Fee Related
- 2003-02-26 US US10/504,679 patent/US7429663B2/en not_active Expired - Fee Related
- 2003-02-26 KR KR1020047013439A patent/KR100935262B1/ko not_active Expired - Fee Related
- 2003-02-26 DE DE60302220T patent/DE60302220T2/de not_active Expired - Lifetime
- 2003-02-26 JP JP2003571286A patent/JP4484524B2/ja not_active Expired - Fee Related
- 2003-02-26 AT AT03709786T patent/ATE309246T1/de active
- 2003-02-26 BR BR0308106-0A patent/BR0308106A/pt active Search and Examination
- 2003-02-26 SI SI200330137T patent/SI1480981T1/sl unknown
- 2003-02-26 EP EP03709786A patent/EP1480981B1/fr not_active Expired - Lifetime
- 2003-02-26 AU AU2003214127A patent/AU2003214127C1/en not_active Ceased
- 2003-02-26 DK DK03709786T patent/DK1480981T3/da active
- 2003-02-26 MX MXPA04008365A patent/MXPA04008365A/es active IP Right Grant
- 2003-02-26 WO PCT/EP2003/002652 patent/WO2003072580A1/fr not_active Ceased
- 2003-02-26 NZ NZ534467A patent/NZ534467A/en not_active IP Right Cessation
- 2003-02-26 CN CNB038079380A patent/CN100441581C/zh not_active Expired - Fee Related
- 2003-02-26 PL PL03372664A patent/PL372664A1/xx not_active IP Right Cessation
- 2003-02-27 TW TW092104221A patent/TWI305534B/zh not_active IP Right Cessation
- 2003-02-28 AR ARP030100658A patent/AR038620A1/es unknown
2004
- 2004-07-29 IL IL163288A patent/IL163288A/en not_active IP Right Cessation
- 2004-08-02 ZA ZA200406154A patent/ZA200406154B/en unknown
- 2004-08-26 NO NO20043567A patent/NO329756B1/no not_active IP Right Cessation
2008
- 2008-08-20 US US12/194,899 patent/US20080318980A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2474875A1 (fr)	2003-09-04
JP4484524B2 (ja)	2010-06-16
PL372664A1 (en)	2005-07-25
NO329756B1 (no)	2010-12-13
ATE309246T1 (de)	2005-11-15
KR20040087328A (ko)	2004-10-13
AR038620A1 (es)	2005-01-19
ZA200406154B (en)	2005-08-02
NZ534467A (en)	2006-07-28
AU2003214127A1 (en)	2003-09-09
AU2003214127C1 (en)	2009-02-05
JP2005519087A (ja)	2005-06-30
US20080318980A1 (en)	2008-12-25
MXPA04008365A (es)	2005-07-26
DE60302220D1 (de)	2005-12-15
SI1480981T1 (sl)	2006-04-30
BR0308106A (pt)	2005-01-04
NO20043567L (no)	2004-11-26
US20050119280A1 (en)	2005-06-02
AU2003214127B2 (en)	2008-07-03
WO2003072580A1 (fr)	2003-09-04
EA007459B1 (ru)	2006-10-27
DE60302220T2 (de)	2006-07-27
EP1480981B1 (fr)	2005-11-09
IL163288A (en)	2009-12-24
EP1340759A1 (fr)	2003-09-03
ES2250876T3 (es)	2006-04-16
TW200418859A (en)	2004-10-01
EA200400937A1 (ru)	2005-02-24
EP1480981A1 (fr)	2004-12-01
KR100935262B1 (ko)	2010-01-06
CA2474875C (fr)	2011-04-12
US7429663B2 (en)	2008-09-30
CN1646533A (zh)	2005-07-27
TWI305534B (en)	2009-01-21
CN100441581C (zh)	2008-12-10

Publication	Publication Date	Title
NO20053955D0 (no)	2005-08-25	Pyrazolo [1,5-A] pyrimidinderivater
DE60016615D1 (de)	2005-01-13	Pyrazolo[4,3-d]pyrimidinderivate
DK1699795T3 (da)	2007-09-10	Substituerede 8'-pyri(mi)dinyldihydrospiro[cycloalkylamin]-pyrimido[1,2-a]pyrimidin-6-onderivater
IL169335A0 (en)	2007-07-04	PYRAZOLO[3,4,-b] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
DK1480981T3 (da)	2006-03-20	1-(Alkyl)-, 1-(heteroaryl)alkyl- og 1-[(aryl)alkyl]-7-(pyrimidin-4-yl) imidazo[1,2a]pyrimidin-5(1H)-onderivater
DE69915675D1 (de)	2004-04-22	Triazolo[4,5-d]pyrimidin-derivate
NO20030033D0 (no)	2003-01-03	Pyrido[2,3-D]pyrimidin- og pyrimido[4,5-D]pyrimidin- nukleosider
EE05351B1 (et)	2010-10-15	Prrolo[2,3-d]primidiinhendid
DE60206946D1 (de)	2005-12-01	Substituierte 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-on- und 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)onderivate gegen neurodegenerative erkrankungen
DK1430057T3 (da)	2006-01-16	Substituerede 2-pyridinyl-6,7,8, 9-tetrahydropyrimido [1,2-a] pyrimidin-4-on- og 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)onderivater
IL163287A (en)	2009-12-24	HETEROARYL SUBSTITUTED 2 - PYRIDINYL AND 2 - PYRIMIDINYL - 6,7,8,9 - TETRAHYDROPYRIMIDO [1,2-a] PYRIMIDIN - 4 - ONE DERIVATIVES
DK1315731T3 (da)	2004-10-11	2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-on og 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)on-derivater
ZA200507192B (en)	2007-03-28	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido [1,2-A] pyrimidin-4-one derivatives
DK1315730T3 (da)	2004-10-25	1-(alkyl)-, 1-[(heteroaryl)alkyl]-og 1-[(aryl)alkyl]-7-pyridinyl-imidazo[1,2-a]pyrimidin-5(1H)-onderivater
AU2003211993A1 (en)	2003-09-04	(1,2,4)TRIAZOLO(1,5-c)PYRIMIDINE DERIVATIVES
PL375709A1 (en)	2005-12-12	Derivatives of [6,7-dihydro-5h-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide
HK1069828A (en)	2005-06-03	1-(alkyl), 1-(heteroaryl)alkyl and 1-[(aryl)alkyl]-7-(pyrimidin-4-yl)-imidazo[1,2-a]pyrimidin-5(1h)-one derivatives
DE50106048D1 (de)	2005-06-02	Substituierte 3,4-dihydro-pyrimido [1,2-a]pyrimidine und 3,4-dihydropyrazino [1,2-a]pyrimidine
ZA200600471B (en)	2007-04-25	7-substituted 3-nitro-pyrazolo[1,5-A] pyrimidines
HK1084664A (en)	2006-08-04	Pyrazolo [1,5-a] pyrimidine derivatives
DK1325010T3 (da)	2005-05-17	Substituerede 3,4-dihydro-pyrimido[1,2-a]pyrimidiner og 3,4-dihydro-pyrazino[1,2-a]pyrimidiner