DK1482042T3 - Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren - Google Patents

Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren

Info

Publication number
DK1482042T3
DK1482042T3 DK04018812T DK04018812T DK1482042T3 DK 1482042 T3 DK1482042 T3 DK 1482042T3 DK 04018812 T DK04018812 T DK 04018812T DK 04018812 T DK04018812 T DK 04018812T DK 1482042 T3 DK1482042 T3 DK 1482042T3
Authority
DK
Denmark
Prior art keywords
inactive
receptor
active
nucleic acid
acid molecules
Prior art date
Application number
DK04018812T
Other languages
Danish (da)
English (en)
Inventor
Gilbert Vassart
Marc Parmentier
Frederique Libert
Michel Samson
Original Assignee
Euroscreen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26144381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1482042(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euroscreen Sa filed Critical Euroscreen Sa
Application granted granted Critical
Publication of DK1482042T3 publication Critical patent/DK1482042T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
DK04018812T 1996-03-01 1997-02-28 Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren DK1482042T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96870021 1996-03-01
EP96870102 1996-08-06
PCT/BE1997/000023 WO1997032019A2 (fr) 1996-03-01 1997-02-28 Recepteur-5 de chimiokine cc, recepteur de chimiokines cc, leurs derives et leurs applications

Publications (1)

Publication Number Publication Date
DK1482042T3 true DK1482042T3 (da) 2009-06-15

Family

ID=26144381

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97904948T DK0883687T3 (da) 1996-03-01 1997-02-28 C-C CKR-5, CC-chemokinreceptor, derivater deraf og anvendelse deraf
DK04018812T DK1482042T3 (da) 1996-03-01 1997-02-28 Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK97904948T DK0883687T3 (da) 1996-03-01 1997-02-28 C-C CKR-5, CC-chemokinreceptor, derivater deraf og anvendelse deraf

Country Status (10)

Country Link
US (6) US6448375B1 (fr)
EP (4) EP0883687B1 (fr)
JP (2) JP4117904B2 (fr)
AT (2) ATE428785T1 (fr)
CA (1) CA2247989C (fr)
DE (2) DE69731373T2 (fr)
DK (2) DK0883687T3 (fr)
ES (2) ES2227672T3 (fr)
PT (1) PT883687E (fr)
WO (1) WO1997032019A2 (fr)

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US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
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US6261763B1 (en) * 1995-06-07 2001-07-17 Progenics Pharmaceuticals, Inc. Fluorescence resonance energy transfer screening assay for the identification of compounds that are capable of abrogating macrophage-tropic HIV-1 cell fusion
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US6344545B1 (en) * 1996-06-14 2002-02-05 Progenics Pharmaceuticals, Inc. Method for preventing HIV-1 infection of CD4+ cells
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
EP0915969A4 (fr) 1996-04-02 2002-04-17 Progenics Pharm Inc Methode de prevention de l'infection des cellules cd4+ par le vih-1
EP0906424A2 (fr) * 1996-04-26 1999-04-07 Incyte Pharmaceuticals, Inc. Recepteurs mixtes mammaliens de lymphocytes et de chimoquine
US5939320A (en) * 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US6258527B1 (en) 1996-05-20 2001-07-10 The Aaron Diamond Aids Research Center Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
EP0975749A2 (fr) 1996-05-28 2000-02-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Recepteur 5 de cc chemokine, anticorps diriges contre ce dernier et animaux transgeniques
US20040086528A1 (en) * 1996-06-14 2004-05-06 Progenics Pharmaceuticals, Inc. Uses of a chemokine receptor for inhibiting HIV-1 infection
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US6388055B1 (en) 1996-10-03 2002-05-14 Smithkline Beecham Corporation Mouse CC-CKR5 receptor polypeptide
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WO1998034945A1 (fr) * 1997-02-06 1998-08-13 Epoch Pharmaceuticals, Inc. Modification ciblee du gene ccr-5
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US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6204024B1 (en) 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
FR2771423A1 (fr) * 1997-11-21 1999-05-28 Transgene Sa Vecteurs permettant d'inhiber ou retarder la liaison d'un virus d'immunodeficience et/ou sa penetration dans une cellule cible
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US20040228869A1 (en) * 1998-12-16 2004-11-18 Progenics Pharmaceuticals, Inc. Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto
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US7304127B2 (en) * 1999-08-27 2007-12-04 United States Of America As Represented By The Secretary, Department Of Health And Human Services Polypeptides that bind HIV gp120 and related nucleic acids, antibodies, compositions, and methods of use
AU6104699A (en) * 1999-09-23 2001-04-24 Isis Innovation Limited Susceptibility gene for inflammatory bowel disease
CA2389196A1 (fr) * 1999-10-28 2001-05-03 Nissui Pharmaceutical Co., Ltd. Peptides cycliques et vaccins contre le sida
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US20030104496A1 (en) * 2001-11-30 2003-06-05 Cytokinetics, Inc. Novel motor protein of P. falciparum and methods for its use
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US20080283557A1 (en) * 2007-05-17 2008-11-20 Julianne Desautels Spout for food stuff container
US20090074766A1 (en) * 2007-09-14 2009-03-19 Ketas Thomas J Methods of inhibiting HIV-2 infection
EP2425001A4 (fr) 2009-04-30 2012-11-14 Univ California Vecteurs d'association anti-vih, vecteurs de ciblage, et procédés d'utilisation
WO2014026053A1 (fr) 2012-08-09 2014-02-13 The Regents Of The University Of California Vecteurs cd25 anti-vih à combinaison pré-sélective, vecteurs de ciblage et procédés d'utilisation
JP2016522679A (ja) * 2013-04-04 2016-08-04 プレジデント アンド フェローズ オブ ハーバード カレッジ ＣＲＩＳＰＲ／Ｃａｓ系を用いたゲノム編集の治療的使用
JP2016528890A (ja) 2013-07-09 2016-09-23 プレジデント アンド フェローズ オブ ハーバード カレッジ ＣＲＩＳＰＲ／Ｃａｓ系を用いるゲノム編集の治療用の使用
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US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
EP0906424A2 (fr) * 1996-04-26 1999-04-07 Incyte Pharmaceuticals, Inc. Recepteurs mixtes mammaliens de lymphocytes et de chimoquine
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Also Published As

Publication number Publication date
US20040110127A1 (en) 2004-06-10
US6930174B2 (en) 2005-08-16
US20020106742A1 (en) 2002-08-08
US6448375B1 (en) 2002-09-10
PT883687E (pt) 2005-02-28
DE69739366D1 (de) 2009-05-28
JP4117904B2 (ja) 2008-07-16
DK0883687T3 (da) 2005-03-07
US6800447B2 (en) 2004-10-05
US20040161739A1 (en) 2004-08-19
EP1199360A2 (fr) 2002-04-24
US7285390B2 (en) 2007-10-23
US20020110870A1 (en) 2002-08-15
EP1482042B1 (fr) 2009-04-15
EP1482042A1 (fr) 2004-12-01
ES2227672T3 (es) 2005-04-01
DE69731373D1 (de) 2004-12-02
ATE280826T1 (de) 2004-11-15
CA2247989C (fr) 2010-12-14
JP2008179639A (ja) 2008-08-07
CA2247989A1 (fr) 1997-09-04
EP0883687A2 (fr) 1998-12-16
ES2325073T3 (es) 2009-08-25
ATE428785T1 (de) 2009-05-15
EP2034023A1 (fr) 2009-03-11
DE69731373T2 (de) 2006-03-09
EP0883687B1 (fr) 2004-10-27
US20020110805A1 (en) 2002-08-15
WO1997032019A2 (fr) 1997-09-04
JP2000505301A (ja) 2000-05-09
WO1997032019A3 (fr) 1997-10-23
US6692938B2 (en) 2004-02-17
EP1199360A3 (fr) 2002-05-02

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