DK174095B1 - Anvendelse af et humant rhinovirus (HRV)-hovedreceptorpræparat til fremstilling af et lægemiddel til inhibering af initieringen eller spredningen af rhino-virusinfektion - Google Patents
Anvendelse af et humant rhinovirus (HRV)-hovedreceptorpræparat til fremstilling af et lægemiddel til inhibering af initieringen eller spredningen af rhino-virusinfektion Download PDFInfo
- Publication number
- DK174095B1 DK174095B1 DK198904312A DK431289A DK174095B1 DK 174095 B1 DK174095 B1 DK 174095B1 DK 198904312 A DK198904312 A DK 198904312A DK 431289 A DK431289 A DK 431289A DK 174095 B1 DK174095 B1 DK 174095B1
- Authority
- DK
- Denmark
- Prior art keywords
- receptor
- hrv
- protein
- icam
- cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23957188A | 1988-09-01 | 1988-09-01 | |
| US23957188 | 1988-09-01 | ||
| US26242888A | 1988-10-25 | 1988-10-25 | |
| US26242888 | 1988-10-25 | ||
| US39066289A | 1989-08-10 | 1989-08-10 | |
| US39066289 | 1989-08-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK431289D0 DK431289D0 (da) | 1989-08-31 |
| DK431289A DK431289A (da) | 1990-03-02 |
| DK174095B1 true DK174095B1 (da) | 2002-06-10 |
Family
ID=27399251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198904312A DK174095B1 (da) | 1988-09-01 | 1989-08-31 | Anvendelse af et humant rhinovirus (HRV)-hovedreceptorpræparat til fremstilling af et lægemiddel til inhibering af initieringen eller spredningen af rhino-virusinfektion |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7132395B1 (de) |
| EP (1) | EP0362531B1 (de) |
| JP (1) | JP3253064B2 (de) |
| AT (1) | ATE186552T1 (de) |
| AU (1) | AU637324B2 (de) |
| CA (1) | CA1339193C (de) |
| DE (1) | DE68929096T2 (de) |
| DK (1) | DK174095B1 (de) |
| ES (1) | ES2141076T3 (de) |
| FI (1) | FI894065A7 (de) |
| GR (1) | GR3032456T3 (de) |
| IL (1) | IL91454A (de) |
| NO (1) | NO893373L (de) |
| NZ (1) | NZ230474A (de) |
| PT (1) | PT91570B (de) |
Families Citing this family (42)
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| US5585264A (en) * | 1988-07-15 | 1996-12-17 | University Of Saskatchewan | Nucleotide sequences encoding recombinant bovine herpesvirus type-1 GI, GIII and GIV polypeptides |
| ES2141076T3 (es) | 1988-09-01 | 2000-03-16 | Bayer Ag | Proteina del receptor de rinovirus humano que inhibe la infectividad del virus. |
| ZA896668B (en) * | 1988-09-01 | 1990-06-27 | Molecular Therapeutics Inc | A human rhinovirus receptor protein that inhibits virus infectivity |
| US6143298A (en) * | 1988-09-01 | 2000-11-07 | Bayer Corporation | Soluble truncated forms of ICAM-1 |
| US6051231A (en) * | 1988-09-01 | 2000-04-18 | Bayer Corporation | Antiviral methods and prepations |
| US6514936B1 (en) | 1988-09-01 | 2003-02-04 | Bayer Corporation | Antiviral methods using human rhinovirus receptor (ICAM-1) |
| NO900155L (no) * | 1989-01-24 | 1990-07-25 | Molecular Therapeutics Inc | Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1. |
| JPH04505009A (ja) * | 1989-03-09 | 1992-09-03 | ダナ・ファーバー・キャンサー・インスティチュート | クローニングlfa―1 |
| ATE219838T1 (de) * | 1989-03-16 | 2002-07-15 | Blood Res Center | Verwendung von funktionellen derivaten des interzellulär-adhäsions-moleküls icam-1 in einer antivirus-therapie |
| WO1991018010A1 (en) * | 1990-05-15 | 1991-11-28 | Swinburne Limited | Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof |
| US5686581A (en) * | 1990-07-20 | 1997-11-11 | Bayer Corporation | Multimeric form of human rhinovirus receptor protein |
| ES2134762T3 (es) * | 1990-07-20 | 1999-10-16 | Bayer Ag | Formas multimericas de proteinas receptoras de rinovirus humanos. |
| US6130202A (en) * | 1990-07-20 | 2000-10-10 | Bayer Corporation | Antiviral methods |
| US5686582A (en) * | 1990-07-20 | 1997-11-11 | Bayer Corporation | Multimeric forms of human rhinovirus receptor protein |
| US6107461A (en) * | 1990-07-20 | 2000-08-22 | Bayer Corporation | Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use |
| US5288854A (en) * | 1990-11-28 | 1994-02-22 | Center For Blood Research, Inc. | Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1 |
| US5629162A (en) * | 1991-06-11 | 1997-05-13 | The Center For Blood Research | Method of identifying agents which modulate ICAM-3 binding to LFA-1 |
| US5525487A (en) * | 1992-01-27 | 1996-06-11 | Icos Corporation | DNA encoding I-CAM related protein |
| US6153395A (en) * | 1992-01-27 | 2000-11-28 | Icos Corporation | ICAM-related protein |
| US5811517A (en) * | 1992-01-27 | 1998-09-22 | Icos Corporation | ICAM-related protein variants |
| US6818743B1 (en) | 1992-01-27 | 2004-11-16 | Icos Corporation | I-CAM related protein |
| US5989843A (en) * | 1992-01-27 | 1999-11-23 | Icos Corporation | Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein |
| US5532127A (en) * | 1992-01-27 | 1996-07-02 | Icos Corporation | Assay for 1-CAM related protein expression |
| WO1993014776A1 (en) * | 1992-01-27 | 1993-08-05 | Icos Corporation | Icam-related protein |
| US5837822A (en) * | 1992-01-27 | 1998-11-17 | Icos Corporation | Humanized antibodies specific for ICAM related protein |
| US6100383A (en) * | 1992-01-27 | 2000-08-08 | Icos Corporation | Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions |
| AU710965B2 (en) * | 1992-06-22 | 1999-09-30 | Bayer Corporation | Multimeric forms of human rhinovirus receptor protein |
| WO1994011400A1 (en) * | 1992-11-18 | 1994-05-26 | Helsinki University Licensing Ltd. Oy | Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis |
| GB9414966D0 (en) * | 1994-07-26 | 1994-09-14 | Danbiosyst Uk | Pharmaceutical compositions for the nasal administration of antiviral agents |
| US5879712A (en) | 1995-06-07 | 1999-03-09 | Sri International | Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced |
| DE69722594T2 (de) * | 1996-03-06 | 2004-04-29 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Pulverförmiges arzneimittel enthaltend interzelluläres adhäsionsmolekül |
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| DK2444079T3 (en) | 2005-05-17 | 2017-01-30 | Sarcode Bioscience Inc | Compositions and Methods for the Treatment of Eye Diseases |
| ES2830024T3 (es) | 2007-10-19 | 2021-06-02 | Novartis Ag | Composiciones y métodos para el tratamiento del edema macular |
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| KR20200108932A (ko) | 2012-07-25 | 2020-09-21 | 에스에이알코드 바이오사이언스 인코포레이티드 | Lfa-1 저해제 및 그의 다형체 |
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| DK0566554T3 (da) | 1992-03-13 | 2000-08-07 | Monsanto Co | Fremstilling af rekombinante proteiner ved anvendelse af herpesviruspromotorer og VP16-transaktivatorer |
| JPH06510208A (ja) | 1992-06-22 | 1994-11-17 | マイルス・インコーポレーテツド | 多量体形態のヒトライノウイルスレセプタ蛋白質 |
| JPH06510673A (ja) | 1992-07-08 | 1994-12-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ヒトライノウイルスに対する結合部位を有する受容体誘導体 |
| US5580969A (en) | 1992-07-24 | 1996-12-03 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ICAM-I RNA |
| WO1994011400A1 (en) | 1992-11-18 | 1994-05-26 | Helsinki University Licensing Ltd. Oy | Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis |
| EP0757697A4 (de) | 1994-04-12 | 2000-05-17 | Boehringer Ingelheim Pharma | Verwendung von agentien, die die interzellülare wechselwirkung inhibieren, in der behandlung von viralen infektionen des atemweges |
| WO1995028170A1 (en) | 1994-04-19 | 1995-10-26 | The University Of Kansas | Icam-1/lfa-1 short-chain peptides and method of using same |
| GB9414966D0 (en) | 1994-07-26 | 1994-09-14 | Danbiosyst Uk | Pharmaceutical compositions for the nasal administration of antiviral agents |
| AU3159595A (en) | 1994-08-30 | 1996-03-22 | Hyal Pharmaceutical Corporation | Hyaluronic acid and derivatives for modulation of cellular activity |
| US5733540A (en) | 1995-03-08 | 1998-03-31 | Lee; Peter Poon-Hang | Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria |
| US5695760A (en) | 1995-04-24 | 1997-12-09 | Boehringer Inglehiem Pharmaceuticals, Inc. | Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation |
| US5879712A (en) | 1995-06-07 | 1999-03-09 | Sri International | Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced |
| ES2222775B1 (es) | 2002-01-31 | 2006-12-16 | Laboratorios Indas, S.A. | Procedimiento para la deteccion de una predisposicion a una enfermedad cardiovascular. |
| AUPS161102A0 (en) | 2002-04-08 | 2002-05-16 | Industrial Engineering Technology Pty Ltd | Improved gas burner |
-
1989
- 1989-08-19 ES ES89115358T patent/ES2141076T3/es not_active Expired - Lifetime
- 1989-08-19 AT AT89115358T patent/ATE186552T1/de not_active IP Right Cessation
- 1989-08-19 DE DE68929096T patent/DE68929096T2/de not_active Expired - Lifetime
- 1989-08-19 EP EP89115358A patent/EP0362531B1/de not_active Expired - Lifetime
- 1989-08-22 NO NO89893373A patent/NO893373L/no unknown
- 1989-08-25 CA CA000609473A patent/CA1339193C/en not_active Expired - Fee Related
- 1989-08-25 AU AU40271/89A patent/AU637324B2/en not_active Ceased
- 1989-08-28 IL IL9145489A patent/IL91454A/en not_active IP Right Cessation
- 1989-08-29 NZ NZ230474A patent/NZ230474A/xx unknown
- 1989-08-30 FI FI894065A patent/FI894065A7/fi not_active Application Discontinuation
- 1989-08-30 PT PT91570A patent/PT91570B/pt not_active IP Right Cessation
- 1989-08-31 DK DK198904312A patent/DK174095B1/da not_active IP Right Cessation
- 1989-09-01 JP JP22730189A patent/JP3253064B2/ja not_active Expired - Lifetime
-
1994
- 1994-09-30 US US08/316,384 patent/US7132395B1/en not_active Expired - Fee Related
-
2000
- 2000-01-25 GR GR20000400150T patent/GR3032456T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI894065A0 (fi) | 1989-08-30 |
| JP3253064B2 (ja) | 2002-02-04 |
| NO893373L (no) | 1990-03-02 |
| JPH02238892A (ja) | 1990-09-21 |
| PT91570B (pt) | 1995-05-31 |
| NO893373D0 (no) | 1989-08-22 |
| FI894065L (fi) | 1990-03-02 |
| AU4027189A (en) | 1990-03-08 |
| AU637324B2 (en) | 1993-05-27 |
| DK431289D0 (da) | 1989-08-31 |
| EP0362531B1 (de) | 1999-11-10 |
| US7132395B1 (en) | 2006-11-07 |
| PT91570A (pt) | 1990-03-30 |
| GR3032456T3 (en) | 2000-05-31 |
| ES2141076T3 (es) | 2000-03-16 |
| DE68929096D1 (de) | 1999-12-16 |
| IL91454A (en) | 1995-08-31 |
| EP0362531A1 (de) | 1990-04-11 |
| DE68929096T2 (de) | 2000-05-11 |
| ATE186552T1 (de) | 1999-11-15 |
| NZ230474A (en) | 1993-03-26 |
| DK431289A (da) | 1990-03-02 |
| FI894065A7 (fi) | 1990-03-02 |
| IL91454A0 (en) | 1990-04-29 |
| CA1339193C (en) | 1997-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |