DK3253911T3 - Fremgangsmåder og anordninger til analyse af partikler - Google Patents

Fremgangsmåder og anordninger til analyse af partikler Download PDF

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Publication number
DK3253911T3
DK3253911T3 DK16746018.7T DK16746018T DK3253911T3 DK 3253911 T3 DK3253911 T3 DK 3253911T3 DK 16746018 T DK16746018 T DK 16746018T DK 3253911 T3 DK3253911 T3 DK 3253911T3
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DK
Denmark
Prior art keywords
methods
devices
analyzing particles
analyzing
particles
Prior art date
Application number
DK16746018.7T
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English (en)
Inventor
Carl Lars Genghis Hansen
Hans Zahn
Jens Huft
Loenhout Marinus Theodorus Johannes Van
Kaston Leung
Bill Kengli Lin
Anders Klaus
Samuel Alves Jana Rodrigues Aparicio
Sohrab Prakash Shah
Adi Steif
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Univ British Columbia
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Publication of DK3253911T3 publication Critical patent/DK3253911T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Flexible containers without fluid transport within
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/14Means for pressure control

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Fluid Mechanics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK16746018.7T 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler DK3253911T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562111755P 2015-02-04 2015-02-04
US201562162039P 2015-05-15 2015-05-15
US201562237690P 2015-10-06 2015-10-06
PCT/CA2016/000031 WO2016123692A1 (en) 2015-02-04 2016-02-04 Methods and devices for analyzing particles

Publications (1)

Publication Number Publication Date
DK3253911T3 true DK3253911T3 (da) 2021-04-06

Family

ID=56563254

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16746018.7T DK3253911T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler
DK20197858.2T DK3792378T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK20197858.2T DK3792378T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Country Status (5)

Country Link
US (3) US10760121B2 (da)
EP (4) EP3253911B1 (da)
CA (1) CA2974632A1 (da)
DK (2) DK3253911T3 (da)
WO (1) WO2016123692A1 (da)

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US10017759B2 (en) 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
US10900065B2 (en) 2014-11-14 2021-01-26 University Of Washington Methods and kits for labeling cellular molecules
DK3253911T3 (da) 2015-02-04 2021-04-06 Univ British Columbia Fremgangsmåder og anordninger til analyse af partikler
WO2017218864A1 (en) * 2016-06-17 2017-12-21 Mayo Foundation For Medical Education And Research Methods and materials for the effective use of combined targeted enrichment of genomic regions and low coverage whole genome sequencing
US11213824B2 (en) 2017-03-29 2022-01-04 The Research Foundation For The State University Of New York Microfluidic device and methods
CN111095018B (zh) * 2017-08-31 2022-03-29 深圳市大疆创新科技有限公司 固态光探测和测距(lidar)系统、用于提高固态光探测和测距(lidar)分辨率的系统和方法
EA202091673A1 (ru) 2018-01-29 2021-02-03 Ст. Джуд Чилдрен'С Рисерч Хоспитал, Инк. Способ амплификации нуклеиновых кислот
CN108363902B (zh) * 2018-01-30 2022-02-25 成都奇恩生物科技有限公司 一种致病遗传变异的精确预测方法
CN112004920B (zh) * 2018-02-05 2024-08-02 斯坦福大学托管董事会 用于单细胞和集合细胞的多重测量的系统和方法
AU2019236328B2 (en) 2018-03-16 2025-10-09 Zoetis Services Llc Peptide vaccines against Interleukin-31
CA3093539A1 (en) 2018-03-16 2019-09-19 Zoetis Services Llc Interleukin-31 monoclonal antibodies for veterinary use
WO2019217099A1 (en) * 2018-05-08 2019-11-14 President And Fellows Of Harvard College Droplet-based single cell genomic dna sequencing
US11574706B2 (en) 2018-06-28 2023-02-07 10X Genomics, Inc. Systems and methods for visualization of single-cell resolution characteristics
US11124829B2 (en) * 2018-06-29 2021-09-21 Illumina, Inc. Flow cells
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
AU2020220461B2 (en) * 2019-02-14 2026-02-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Haplotagging - haplotype phasing and single-tube combinatorial barcoding of nucleic acid molecules using bead-immobilized Tn5 transposase
US11976269B2 (en) * 2019-03-18 2024-05-07 Cellular Research, Inc. Precise delivery of components into fluids
BR112022002365A2 (pt) 2019-08-09 2022-04-26 Nutcracker Therapeutics Inc Métodos e aparelhos para fabricar e para remover material de uma composição terapêutica
WO2021097456A1 (en) * 2019-11-17 2021-05-20 The Regents Of The University Of California Guided Microfluidic Flow for Cell Capture, Indexing, and Directed Release
EP4103321A4 (en) 2020-03-30 2023-05-10 Hewlett-Packard Development Company, L.P. FLUID EJECTION MATRIX WITH INWARD-CURVING ANTCHAMBER SIDEWALLS
CA3202814A1 (en) * 2020-12-22 2022-06-30 Hifibio Sas Microfluidic methods and systems
US20230220501A1 (en) * 2022-01-13 2023-07-13 Whitworth University Pathogen detection system
US20250154600A1 (en) * 2022-03-07 2025-05-15 Cedars-Sinai Medical Center Method for detecting cancer and tumor invasiveness using dna palindromes as a biomarker
US20250197924A1 (en) * 2023-12-15 2025-06-19 Amazon Technologies, Inc. Methods for selection and combination of sequencing results from biological samples for neoantigen scoring

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US7195670B2 (en) * 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
US7118910B2 (en) * 2001-11-30 2006-10-10 Fluidigm Corporation Microfluidic device and methods of using same
KR20100028526A (ko) * 2007-02-05 2010-03-12 마이크로칩 바이오테크놀로지스, 인크. 마이크로유체 및 나노유체 장치, 시스템 및 응용
EP2212437A4 (en) * 2007-11-07 2011-09-28 Univ British Columbia MICROFLUIDIC DEVICE AND METHOD OF USING THE DEVICE
US9080211B2 (en) 2008-10-24 2015-07-14 Epicentre Technologies Corporation Transposon end compositions and methods for modifying nucleic acids
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
CA3080686C (en) 2010-10-22 2023-10-10 Cold Spring Harbor Laboratory Varietal counting of nucleic acids for obtaining genomic copy number information
CN102533960B (zh) * 2010-12-31 2014-04-30 深圳华大基因科技有限公司 一种单细胞基因组分析方法及试剂盒
WO2012162779A1 (en) 2011-05-27 2012-12-06 The University Of British Columbia Microfluidic cell trap and assay apparatus for high-throughput analysis
US10017759B2 (en) * 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
WO2016115537A2 (en) * 2015-01-15 2016-07-21 Massachusetts Institute Of Technology Systems, methods, and apparatus for in vitro single-cell identification and recovery
DK3253911T3 (da) 2015-02-04 2021-04-06 Univ British Columbia Fremgangsmåder og anordninger til analyse af partikler

Also Published As

Publication number Publication date
US10760121B2 (en) 2020-09-01
EP4450635A3 (en) 2025-01-22
EP3792378A1 (en) 2021-03-17
DK3792378T3 (da) 2023-11-27
EP3253911A1 (en) 2017-12-13
EP3253911A4 (en) 2018-07-04
EP4273262A2 (en) 2023-11-08
CA2974632A1 (en) 2016-08-11
EP3253911B1 (en) 2021-01-20
US20200332357A1 (en) 2020-10-22
WO2016123692A1 (en) 2016-08-11
US11434530B2 (en) 2022-09-06
EP4273262A3 (en) 2023-12-27
EP3792378B1 (en) 2023-08-23
EP4450635A2 (en) 2024-10-23
US20180010179A1 (en) 2018-01-11
US20230091562A1 (en) 2023-03-23

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