DK3436591T3 - Adenovirale coat-protein-afledte transportvehikler - Google Patents

Adenovirale coat-protein-afledte transportvehikler Download PDF

Info

Publication number: DK3436591T3
Authority: DK; Denmark
Prior art keywords: coat protein; transport vehicles; adenoviral coat; derived transport; derived
Prior art date: 2016-03-31

Application number

DK17715444.0T

Other languages

English (en)

Other versions

DK3436591T5 (da

Inventor

Imre Berger

Frédéric Garzoni

Pascal Fender

Original Assignee

The European Molecular Biology Laboratory

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-03-31

Filing date

2017-03-31

Publication date

2023-03-20

2017-03-31 Application filed by The European Molecular Biology Laboratory, Centre Nat Rech Scient filed Critical The European Molecular Biology Laboratory

2023-03-20 Application granted granted Critical

2023-03-20 Publication of DK3436591T3 publication Critical patent/DK3436591T3/da

2024-09-16 Publication of DK3436591T5 publication Critical patent/DK3436591T5/da

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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10023—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10323—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Plant Pathology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Physics & Mathematics (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK17715444.0T 2016-03-31 2017-03-31 Adenovirale coat-protein-afledte transportvehikler DK3436591T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP16163372		2016-03-31
PCT/EP2017/057747 WO2017167988A1 (en)	2016-03-31	2017-03-31	Adenoviral coat protein derived delivery vehicles

Publications (2)

Publication Number	Publication Date
DK3436591T3 true DK3436591T3 (da)	2023-03-20
DK3436591T5 DK3436591T5 (da)	2024-09-16

Family

ID=55650297

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK17715444.0T DK3436591T5 (da)	2016-03-31	2017-03-31	Adenovirale coat-protein-afledte transportvehikler

Country Status (17)

Country	Link
US (2)	US11274127B2 (da)
EP (2)	EP3436591B1 (da)
JP (4)	JP7466271B2 (da)
CN (2)	CN109415739A (da)
CA (2)	CA3280183A1 (da)
DK (1)	DK3436591T5 (da)
ES (2)	ES2941339T3 (da)
FI (1)	FI3436591T3 (da)
HR (1)	HRP20230197T1 (da)
HU (2)	HUE061690T2 (da)
LT (1)	LT3436591T (da)
PL (1)	PL3436591T3 (da)
PT (1)	PT3436591T (da)
RS (1)	RS64059B1 (da)
SI (1)	SI3436591T1 (da)
SM (1)	SMT202300106T1 (da)
WO (1)	WO2017167988A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3436591B1 (en)	2016-03-31	2023-01-04	The European Molecular Biology Laboratory	Adenoviral coat protein derived delivery vehicles
CA3070040A1 (en)	2017-08-29	2019-03-07	Ruprecht-Karls-Universitat Heidelberg	Rationally designed virus-like particles for modulation of chimeric antigen receptor (car)-t-cell therapy
SG11202100898UA (en)	2018-07-31	2021-02-25	Imophoron Ltd	Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base
MX2022009574A (es)	2020-02-05	2022-11-16	Imophoron Ltd	Polipéptidos modificados derivados de dominio variable de la base pentona de adenovirus.
WO2022121917A1 (zh) *	2020-12-11	2022-06-16	康希诺生物股份公司	一种药物组合物及其应用
WO2022218997A1 (en)	2021-04-12	2022-10-20	Centre National De La Recherche Scientifique (Cnrs)	Novel universal vaccine presenting system
CN114805599B (zh) *	2022-03-29	2023-08-04	华南农业大学	一种基于ADDomer嵌合猪O型口蹄疫病毒抗原表位的VLPs及应用
WO2024042100A1 (en)	2022-08-22	2024-02-29	Imophoron Limited	Adenovirus penton-based virus-like particles
WO2024192321A2 (en) *	2023-03-16	2024-09-19	Brown University	Sulfine-based compounds for generating hydrogen persulfide
CN118459559B (zh) *	2024-07-10	2024-11-15	首都儿科研究所	用于制备多型腺病毒通用检测抗体的多肽、人工抗原、多克隆抗体及应用

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US6083720A (en) *	1995-11-13	2000-07-04	Chroboczek; Jadwiga	Dodecahedral adenoviral protein complex, composition containing same and uses thereof
EP0866721A4 (en)	1995-12-08	2003-06-04	Univ Alabama Birmingham Res Fo	TARGET ADENOVIRAL VECTORS
AU2001265154A1 (en)	2000-05-31	2001-12-11	Genvec, Inc.	Method and composition for targeting an adenoviral vector
WO2005075506A1 (en) *	2004-01-09	2005-08-18	The Scripps Research Institute	Identification of endogenous trimerization domains in the adenovirus fiber protein that allow detargeting and retargeting of viral vectors
ATE449105T1 (de)	2004-01-23	2009-12-15	Angeletti P Ist Richerche Bio	Impfstoffträger für schimpansen-adenovirus
AU2006284756B2 (en) *	2005-08-31	2012-06-07	Genvec, Inc.	Adenoviral vector-based malaria vaccines
WO2007094653A1 (en) *	2006-02-13	2007-08-23	Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg	Adenovirus particles having a chimeric adenovirus spike protein, use thereof and methods for producing such particles.
EP2391638B1 (en)	2009-02-02	2018-06-27	GlaxoSmithKline Biologicals SA	Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof
PL222496B1 (pl) *	2009-04-10	2016-08-31	Inst Biochemii I Biofizyki Pan	Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania oraz kompozycja farmaceutyczna zawierająca wektorową cząsteczkę wirusopodobną
PL222497B1 (pl) *	2009-06-26	2016-08-31	Inst Biochemii I Biofizyki Pan	Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej
US9862931B2 (en) *	2010-04-28	2018-01-09	Institut Gustave Roussy	Adenovirus vaccine vectors
CN104271748B9 (zh) *	2012-02-02	2019-05-24	得克萨斯州大学系统董事会	表达异源肿瘤相关抗原的腺病毒
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PE20180241A1 (es) *	2015-04-30	2018-01-31	Psioxus Therapeutics Ltd	Adenovirus oncolitico que codifica una proteina b7
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EP3436591B1 (en)	2016-03-31	2023-01-04	The European Molecular Biology Laboratory	Adenoviral coat protein derived delivery vehicles

2017
- 2017-03-31 EP EP17715444.0A patent/EP3436591B1/en active Active
- 2017-03-31 SI SI201731329T patent/SI3436591T1/sl unknown
- 2017-03-31 PT PT177154440T patent/PT3436591T/pt unknown
- 2017-03-31 SM SM20230106T patent/SMT202300106T1/it unknown
- 2017-03-31 HR HRP20230197TT patent/HRP20230197T1/hr unknown
- 2017-03-31 EP EP22216930.2A patent/EP4190906B1/en active Active
- 2017-03-31 CN CN201780021098.0A patent/CN109415739A/zh active Pending
- 2017-03-31 CA CA3280183A patent/CA3280183A1/en active Pending
- 2017-03-31 WO PCT/EP2017/057747 patent/WO2017167988A1/en not_active Ceased
- 2017-03-31 ES ES17715444T patent/ES2941339T3/es active Active
- 2017-03-31 US US16/088,905 patent/US11274127B2/en active Active
- 2017-03-31 RS RS20230209A patent/RS64059B1/sr unknown
- 2017-03-31 HU HUE17715444A patent/HUE061690T2/hu unknown
- 2017-03-31 FI FIEP17715444.0T patent/FI3436591T3/fi active
- 2017-03-31 PL PL17715444.0T patent/PL3436591T3/pl unknown
- 2017-03-31 CN CN202311358393.9A patent/CN117534735A/zh active Pending
- 2017-03-31 JP JP2018551787A patent/JP7466271B2/ja active Active
- 2017-03-31 ES ES22216930T patent/ES3044922T3/es active Active
- 2017-03-31 LT LTEPPCT/EP2017/057747T patent/LT3436591T/lt unknown
- 2017-03-31 HU HUE22216930A patent/HUE072880T2/hu unknown
- 2017-03-31 DK DK17715444.0T patent/DK3436591T5/da active
- 2017-03-31 CA CA3018427A patent/CA3018427C/en active Active
2022
- 2022-02-01 US US17/590,444 patent/US12122806B2/en active Active
- 2022-08-05 JP JP2022125445A patent/JP2022166109A/ja active Pending
- 2022-08-05 JP JP2022125446A patent/JP2022166110A/ja active Pending
2024
- 2024-07-22 JP JP2024116678A patent/JP2024160245A/ja active Pending

Also Published As

Publication number	Publication date
HUE072880T2 (hu)	2025-12-28
EP4190906C0 (en)	2025-08-20
SI3436591T1 (sl)	2023-05-31
CN117534735A (zh)	2024-02-09
RS64059B1 (sr)	2023-04-28
EP3436591A1 (en)	2019-02-06
EP3436591B1 (en)	2023-01-04
JP2024160245A (ja)	2024-11-13
PL3436591T3 (pl)	2023-06-26
US20200325179A1 (en)	2020-10-15
EP4190906B1 (en)	2025-08-20
US11274127B2 (en)	2022-03-15
HUE061690T2 (hu)	2023-08-28
JP2022166110A (ja)	2022-11-01
CA3018427C (en)	2025-11-18
DK3436591T5 (da)	2024-09-16
PT3436591T (pt)	2023-04-11
HRP20230197T1 (hr)	2023-03-31
CN109415739A (zh)	2019-03-01
ES2941339T3 (es)	2023-05-22
LT3436591T (lt)	2023-04-11
ES3044922T3 (en)	2025-11-27
FI3436591T3 (fi)	2023-03-30
EP4190906A1 (en)	2023-06-07
SMT202300106T1 (it)	2023-05-12
US12122806B2 (en)	2024-10-22
JP2022166109A (ja)	2022-11-01
JP2019512261A (ja)	2019-05-16
JP7466271B2 (ja)	2024-04-12
CA3280183A1 (en)	2026-03-02
WO2017167988A1 (en)	2017-10-05
CA3018427A1 (en)	2017-10-05
US20220162267A1 (en)	2022-05-26

Publication	Publication Date	Title
DK3436591T5 (da)	2024-09-16	Adenovirale coat-protein-afledte transportvehikler
IL270896A (en)	2020-01-30	Chimeric antigen receptors targeting flt3
DK3401186T3 (da)	2020-02-24	Artikeltransportkøretøj
CL2016001960S1 (es)	2017-01-20	Automovil
CL2016002006S1 (es)	2017-01-20	Automovil
CL2016002093S1 (es)	2017-01-20	Automovil
CL2018001630S1 (es)	2018-12-21	Automóvil
EP3533728A4 (en)	2020-05-27	HIGH RAILWAY TRANSPORT VEHICLE
CL2016002796S1 (es)	2017-09-08	Automóvil
CL2017000733S1 (es)	2018-04-27	Automóvil
CL2016002472S1 (es)	2017-08-11	Automóvil
EP3325375A4 (en)	2019-02-20	FÖRDERSYSTEME
IL265212B (en)	2022-05-01	Charge management system
UA35043S (uk)	2017-08-10	Автомобіль
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DK3205564T3 (da)	2019-09-23	Ladcykel
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