DK462688A - Anvendelse af nukleosider til fremstilling af laegemiddel til behandling af sygdomme foraarsaget af retrovirus eller hepatitis b virus - Google Patents
Anvendelse af nukleosider til fremstilling af laegemiddel til behandling af sygdomme foraarsaget af retrovirus eller hepatitis b virusInfo
- Publication number
- DK462688A DK462688A DK462688A DK462688A DK462688A DK 462688 A DK462688 A DK 462688A DK 462688 A DK462688 A DK 462688A DK 462688 A DK462688 A DK 462688A DK 462688 A DK462688 A DK 462688A
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atoms
- treatment
- retrovirus
- hepatitis
- virus
- Prior art date
Links
- 241001430294 unidentified retrovirus Species 0.000 title abstract 2
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000002777 nucleoside Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 beta -D-arabinofuranosyl Chemical group 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000002672 hepatitis B Diseases 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000004950 trifluoroalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8605503A SE8605503D0 (sv) | 1986-12-19 | 1986-12-19 | Novel medicinal use |
| PCT/SE1987/000608 WO1988004662A1 (en) | 1986-12-19 | 1987-12-16 | Use of nucleosides for the manufacture of medicament for treatment of diseases caused by retrovirus or hepatitis b virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK462688A true DK462688A (da) | 1988-08-18 |
| DK462688D0 DK462688D0 (da) | 1988-08-18 |
Family
ID=20366710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK462688A DK462688D0 (da) | 1986-12-19 | 1988-08-18 | Anvendelse af nukleosider til fremstilling af laegemiddel til behandling af sygdomme foraarsaget af retrovirus eller hepatitis b virus |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0294443B1 (de) |
| JP (1) | JPH01501551A (de) |
| AT (1) | ATE78824T1 (de) |
| AU (1) | AU607965B2 (de) |
| CA (1) | CA1306695C (de) |
| DE (1) | DE3780814T2 (de) |
| DK (1) | DK462688D0 (de) |
| SE (1) | SE8605503D0 (de) |
| WO (1) | WO1988004662A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68917479D1 (de) * | 1988-02-24 | 1994-09-15 | Inst Rech Chim Biolog | Derivate von deoxy-2'-uridin substituiert in der 5, 3' oder 5' stellung durch acylierte alpha-amino-gruppen, verfahren zur herstellung und arzneimittel daraus. |
| SE8802173D0 (sv) * | 1988-06-10 | 1988-06-10 | Astra Ab | Pyrimidine derivatives |
| SE8802687D0 (sv) * | 1988-07-20 | 1988-07-20 | Astra Ab | Nucleoside derivatives |
| DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
| US6001840A (en) * | 1990-03-06 | 1999-12-14 | Southern Research Institute | Methods of treatment of viral infections using carbocyclic deoxyguanosine analogs |
| GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
| GB9125271D0 (en) * | 1991-11-27 | 1992-01-29 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
| JPH10507763A (ja) * | 1994-10-24 | 1998-07-28 | ジェネンコア インターナショナル インコーポレーテッド | L−ピラノシルヌクレオシド |
| US5559101A (en) * | 1994-10-24 | 1996-09-24 | Genencor International, Inc. | L-ribofuranosyl nucleosides |
| EP1425022A4 (de) * | 2001-08-24 | 2009-04-29 | Koronis Pharmaceuticals Inc | Mutagene nucleosid-analoga zur behandlung von viruserkrankungen |
| AU2002360697B2 (en) * | 2001-12-20 | 2009-04-23 | Beth Israel Deaconess Medical Center | Treatment of EBV and KHSV infection and associated abnormal cellular proliferation |
| US8697357B2 (en) | 2008-03-12 | 2014-04-15 | Japan Advanced Institute Of Science And Technology | Method for detection of methylcytosine using photoresponsive probe |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3328388A (en) * | 1964-09-02 | 1967-06-27 | Merck & Co Inc | Arabinofuranosyl pyrimidines and methods of preparing same |
| DE1620185C3 (de) * | 1966-03-02 | 1982-01-14 | Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen | 5-Äthyl- und 5-Propyl-2'-deoxyuridin, Verfahren zur Herstellung dieser Verbindungen und diese Verbindungen enthaltende Arzneimittel |
| AT281862B (de) * | 1968-07-11 | 1970-06-10 | Robugen Gmbh | Verfahren zur Herstellung von neuen 2'-Desoxyuridinen |
| GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
| US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
| US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
| JPS5639019A (en) * | 1979-09-05 | 1981-04-14 | Yamasa Shoyu Co Ltd | Antiviral agent |
| GB2060604B (en) * | 1979-10-03 | 1983-11-23 | Univ Birmingham And Stichting | E15-(2-halogenovinyl)-2'-deoxycytidines |
| JPS5687599A (en) * | 1979-12-19 | 1981-07-16 | Yamasa Shoyu Co Ltd | E 55 22halogenovinyl arabinofuranosyluracil and its preparation |
| DE3045375A1 (de) * | 1980-12-02 | 1982-07-01 | Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen | Neue substituierte pyrimidin-nukleoside mit antiviraler wirkung, verfahren zu deren herstellung und daraus zubereitete arzneiformen |
| FI832884A7 (fi) * | 1982-08-17 | 1984-02-18 | Sandoz Ag | Desoksiuridiini-johdannaiset, niiden valmistusmenetelmät ja käyttö farmaseuttisina aineina. |
| JPS5979658A (ja) * | 1982-10-28 | 1984-05-08 | Fujitsu Ltd | 複合交換機 |
| IL78158A (en) * | 1985-03-16 | 1988-04-29 | Wellcome Found | Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine |
| EP0258412A1 (de) * | 1986-02-20 | 1988-03-09 | GREER, Sheldon B. | Zubereitung und verfahren zur behandlung von aids und verwandten krankheiten |
-
1986
- 1986-12-19 SE SE8605503A patent/SE8605503D0/xx unknown
-
1987
- 1987-12-16 AT AT88900484T patent/ATE78824T1/de not_active IP Right Cessation
- 1987-12-16 WO PCT/SE1987/000608 patent/WO1988004662A1/en not_active Ceased
- 1987-12-16 JP JP63501162A patent/JPH01501551A/ja active Pending
- 1987-12-16 DE DE8888900484T patent/DE3780814T2/de not_active Expired - Lifetime
- 1987-12-16 AU AU10834/88A patent/AU607965B2/en not_active Ceased
- 1987-12-16 EP EP88900484A patent/EP0294443B1/de not_active Expired - Lifetime
- 1987-12-18 CA CA000554775A patent/CA1306695C/en not_active Expired - Fee Related
-
1988
- 1988-08-18 DK DK462688A patent/DK462688D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3780814D1 (de) | 1992-09-03 |
| CA1306695C (en) | 1992-08-25 |
| AU607965B2 (en) | 1991-03-21 |
| EP0294443B1 (de) | 1992-07-29 |
| WO1988004662A1 (en) | 1988-06-30 |
| DE3780814T2 (de) | 1992-12-10 |
| DK462688D0 (da) | 1988-08-18 |
| SE8605503D0 (sv) | 1986-12-19 |
| JPH01501551A (ja) | 1989-06-01 |
| ATE78824T1 (de) | 1992-08-15 |
| EP0294443A1 (de) | 1988-12-14 |
| AU1083488A (en) | 1988-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |