EA202192519A1 - Системы и способы для получения ускоренных кильватерным полем электронов и рентгеновских лучей с использованием компактного лазера - Google Patents

Системы и способы для получения ускоренных кильватерным полем электронов и рентгеновских лучей с использованием компактного лазера

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Publication number
EA202192519A1
EA202192519A1 EA202192519A EA202192519A EA202192519A1 EA 202192519 A1 EA202192519 A1 EA 202192519A1 EA 202192519 A EA202192519 A EA 202192519A EA 202192519 A EA202192519 A EA 202192519A EA 202192519 A1 EA202192519 A1 EA 202192519A1
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EA
Eurasian Patent Office
Prior art keywords
laser
source
electron beam
systems
plasma target
Prior art date
Application number
EA202192519A
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English (en)
Inventor
Тосики Тадзима
Жерар Муру
Данте Роа
Алес Некас
Original Assignee
Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния
Таэ Текнолоджиз, Инк.
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Application filed by Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния, Таэ Текнолоджиз, Инк. filed Critical Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния
Publication of EA202192519A1 publication Critical patent/EA202192519A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H15/00—Methods or devices for acceleration of charged particles not otherwise provided for, e.g. wakefield accelerators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4021—Arrangements for generating radiation specially adapted for radiation diagnosis involving movement of the focal spot
    • A61B6/4028—Arrangements for generating radiation specially adapted for radiation diagnosis involving movement of the focal spot resulting in acquisition of views from substantially different positions, e.g. EBCT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/087—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N5/1015—Treatment of resected cavities created by surgery, e.g. lumpectomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/04—Positioning of patients; Tiltable beds or the like
    • A61B6/0407—Supports, e.g. tables or beds, for the body or parts of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/15—Laboratory, medical or dentistry appliances, e.g. catheters or sharps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A61N2005/1088—Ions; Protons generated by laser radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1089—Electrons
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05G—X-RAY TECHNIQUE
    • H05G2/00—Apparatus or processes specially adapted for producing X-rays, not involving X-ray tubes, e.g. involving generation of a plasma
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H2277/00—Applications of particle accelerators
    • H05H2277/10—Medical devices
    • H05H2277/11—Radiotherapy
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H2277/00—Applications of particle accelerators
    • H05H2277/10—Medical devices
    • H05H2277/11—Radiotherapy
    • H05H2277/113—Diagnostic systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Plasma & Fusion (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Radiation-Therapy Devices (AREA)
  • Particle Accelerators (AREA)

Abstract

Система с использованием пучков электронов, индуцируемых лазерным ускорением кильватерного поля (LWFA), для терапии рака и диагностики. Примеры варианта осуществления, представленные в настоящем описании, содержат одно или более лазерных волокон, а также источник пучка электронов в отдельном упомянутом одном или более лазерных волокнах, при этом источник пучка электронов включает в себя источник лазерных импульсов, плазменную мишень, набор оптики, помещенный между источником лазерных импульсов и плазменной мишенью и выполненный с возможностью фокусировки лазерного импульса, генерируемого источником лазерных импульсов, на плазменную мишень, при этом взаимодействие лазерного импульса с плазменной мишенью индуцирует генерацию пучка электронов. В различных вариантах осуществления, представленных в настоящем описании, электроны высокой энергии пучка электронов взаимодействуют с материалом с высоким Z для генерации рентгеновского излучения.
EA202192519A 2019-03-18 2020-03-18 Системы и способы для получения ускоренных кильватерным полем электронов и рентгеновских лучей с использованием компактного лазера EA202192519A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962819918P 2019-03-18 2019-03-18
PCT/US2020/023394 WO2020191074A1 (en) 2019-03-18 2020-03-18 Systems and methods for compact laser wakefield accelerated electrons and x-rays

Publications (1)

Publication Number Publication Date
EA202192519A1 true EA202192519A1 (ru) 2021-12-10

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Country Status (11)

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US (1) US20220117075A1 (ru)
EP (1) EP3941353A4 (ru)
JP (1) JP2022525912A (ru)
KR (1) KR20210139380A (ru)
CN (1) CN114269249A (ru)
AU (1) AU2020240068A1 (ru)
CA (1) CA3134044A1 (ru)
EA (1) EA202192519A1 (ru)
MX (1) MX2021011329A (ru)
SG (1) SG11202110149PA (ru)
WO (1) WO2020191074A1 (ru)

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CN115696710B (zh) * 2022-10-20 2025-12-05 中国工程物理研究院激光聚变研究中心 一种基于微通道器件的等离子体制备装置及制备方法
CN120676989A (zh) * 2023-02-13 2025-09-19 赫尔思国际解决方案有限公司 用于放射疗法验证的立方体电子检测器阵列
CN119471775B (zh) * 2024-11-15 2025-09-05 中国人民解放军国防科技大学 一种模拟空间轨道电子辐射环境的方法和系统

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US6087666A (en) * 1998-02-18 2000-07-11 The United States Of America As Represented By The Secretary Of The Navy Optically stimulated luminescent fiber optic radiation dosimeter
US6962587B2 (en) * 2000-07-25 2005-11-08 Rita Medical Systems, Inc. Method for detecting and treating tumors using localized impedance measurement
EP1314451B1 (en) * 2001-11-23 2009-07-01 Nucletron B.V. Device for effecting radiation therapy in an animal body
DE10341538A1 (de) * 2003-01-13 2004-07-22 Siemens Ag Röntgenquelle
JP4713362B2 (ja) * 2006-02-16 2011-06-29 学校法人光産業創成大学院大学 遺伝子改変装置
WO2012045040A1 (en) * 2010-10-01 2012-04-05 Varian Medical Systems, Inc. Laser accelerator driven particle brachytherapy devices, systems, and methods
HUE039588T2 (hu) * 2012-09-14 2019-01-28 Ecole Polytech Elrendezés protonnyaláb elõállítására és berendezés radioaktív hulladékok átalakítására
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EP2846422A1 (en) * 2013-09-09 2015-03-11 Ecole Polytechnique Free-Electron Laser driven by fibre based laser feeding a Laser Plasma Accelerator
US9839113B2 (en) * 2014-03-14 2017-12-05 The Regents Of The University Of California Solid media wakefield accelerators

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CA3134044A1 (en) 2020-09-24
KR20210139380A (ko) 2021-11-22
MX2021011329A (es) 2022-01-06
AU2020240068A1 (en) 2021-10-21
US20220117075A1 (en) 2022-04-14
JP2022525912A (ja) 2022-05-20
WO2020191074A1 (en) 2020-09-24
EP3941353A4 (en) 2022-12-14
CN114269249A (zh) 2022-04-01
SG11202110149PA (en) 2021-10-28
EP3941353A1 (en) 2022-01-26

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