EE200200274A - Pürrolidiinatseetamiidi derivaadi kasutamine ravimi valmistamiseks, mis on ette nähtud kesknärvisüsteemi häirete ravimiseks, ja farmatseutiline kompositsioon - Google Patents
Pürrolidiinatseetamiidi derivaadi kasutamine ravimi valmistamiseks, mis on ette nähtud kesknärvisüsteemi häirete ravimiseks, ja farmatseutiline kompositsioonInfo
- Publication number
- EE200200274A EE200200274A EEP200200274A EEP200200274A EE200200274A EE 200200274 A EE200200274 A EE 200200274A EE P200200274 A EEP200200274 A EE P200200274A EE P200200274 A EEP200200274 A EE P200200274A EE 200200274 A EE200200274 A EE 200200274A
- Authority
- EE
- Estonia
- Prior art keywords
- medicament
- disorders
- manufacture
- treatment
- pharmaceutical composition
- Prior art date
Links
- JZQKDDCNNQFGRM-UHFFFAOYSA-N acetamide;pyrrolidine Chemical class CC(N)=O.C1CCNC1 JZQKDDCNNQFGRM-UHFFFAOYSA-N 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99123803 | 1999-12-01 | ||
| EP99124269 | 1999-12-01 | ||
| PCT/EP2000/011808 WO2001039779A1 (en) | 1999-12-01 | 2000-11-27 | A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200274A true EE200200274A (et) | 2003-06-16 |
Family
ID=26153183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200274A EE200200274A (et) | 1999-12-01 | 2000-11-27 | Pürrolidiinatseetamiidi derivaadi kasutamine ravimi valmistamiseks, mis on ette nähtud kesknärvisüsteemi häirete ravimiseks, ja farmatseutiline kompositsioon |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US6903130B1 (es) |
| EP (4) | EP1244456B1 (es) |
| JP (2) | JP4249415B2 (es) |
| KR (1) | KR20030016205A (es) |
| CN (1) | CN100525761C (es) |
| AR (1) | AR026610A1 (es) |
| AT (1) | ATE361751T1 (es) |
| AU (1) | AU773418B2 (es) |
| BG (1) | BG106708A (es) |
| BR (1) | BR0015974A (es) |
| CA (2) | CA2475026A1 (es) |
| CO (1) | CO5261590A1 (es) |
| CZ (1) | CZ20021904A3 (es) |
| DE (1) | DE60034815T2 (es) |
| EE (1) | EE200200274A (es) |
| ES (1) | ES2287039T3 (es) |
| HK (1) | HK1052647B (es) |
| HU (1) | HUP0204023A3 (es) |
| IL (2) | IL149530A0 (es) |
| IS (1) | IS6377A (es) |
| MX (1) | MXPA02005275A (es) |
| MY (1) | MY127980A (es) |
| NO (1) | NO20022585L (es) |
| NZ (1) | NZ518901A (es) |
| PL (1) | PL357472A1 (es) |
| RO (1) | RO121085B1 (es) |
| RU (1) | RU2261093C2 (es) |
| SA (1) | SA01210655B1 (es) |
| SK (1) | SK7492002A3 (es) |
| TW (1) | TWI238062B (es) |
| WO (1) | WO2001039779A1 (es) |
| YU (1) | YU37602A (es) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0004297D0 (en) | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| KR100823668B1 (ko) * | 2000-12-28 | 2008-04-21 | 해밀턴 파마슈티컬스 인코포레이티드 | 신경성 통증 치료 및 예방약 |
| US20040116505A1 (en) * | 2001-02-23 | 2004-06-17 | Gregory Krauss | Treatment of tics, tremors and related disorders |
| EP1406872B1 (en) * | 2001-06-20 | 2007-12-19 | Merck & Co., Inc. | Dipeptidyl peptidase inhibitors for the treatment of diabetes |
| US7544681B2 (en) | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
| AU2002340971B2 (en) * | 2001-10-08 | 2007-04-26 | Ucb | Use of 2-oxo-1-pyrrolidine derivatives for the treatment of dyskinesia and movement disorders |
| WO2003094913A1 (en) * | 2002-05-14 | 2003-11-20 | Ucb, S.A. | Use of 2-oxo-1-pyrrolidone derivatives for the preparation of a drug |
| JP2006516390A (ja) | 2002-12-03 | 2006-07-06 | ユ セ ベ ソシエテ アノニム | 発作、神経系疾患、内分泌障害及びホルモン疾患の治療用薬剤の同定方法 |
| WO2004052350A2 (en) * | 2002-12-11 | 2004-06-24 | Taro Pharmaceutical Industries Limited | Method of treating movement disorders using barbituric acid derivatives |
| US20050143445A1 (en) * | 2003-03-18 | 2005-06-30 | Parthasaradhi Reddy B. | Novel crystalline forms of levetiracetam |
| GB0307860D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Organic compounds |
| JPWO2004093910A1 (ja) * | 2003-04-22 | 2006-07-13 | アステラス製薬株式会社 | PPARδアゴニストによる脳神経変性疾患治療剤 |
| WO2005032535A1 (ja) | 2003-10-03 | 2005-04-14 | Ono Pharmaceutical Co., Ltd. | 神経再生促進剤 |
| JP2008534522A (ja) * | 2005-03-30 | 2008-08-28 | ジェンファーム インク | 医薬組成物のための複合ステップ製造方法 |
| US20060252745A1 (en) | 2005-05-06 | 2006-11-09 | Almeida Jose L D | Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use |
| WO2006127300A1 (en) * | 2005-05-24 | 2006-11-30 | Cambrex Charles City, Inc. | SYNTHESIS OF (S)-α-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE |
| KR20080030546A (ko) | 2005-07-26 | 2008-04-04 | 유씨비 파마, 에스.에이. | 레베티라세탐을 포함하는 약제 조성물 및 이의 제조 방법 |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| FR2890563B1 (fr) * | 2005-09-09 | 2007-10-19 | Servier Lab | Nouvelle association entre l'agomelatine et un agent thymoregulateur et les compositions pharmaceutiques qui la contiennent |
| WO2007086891A1 (en) * | 2006-01-24 | 2007-08-02 | Teva Pharmaceutical Industries Ltd. | Levetiracetam formulations and methods for their manufacture |
| EA019757B1 (ru) * | 2006-06-15 | 2014-06-30 | ЮСиБи ФАРМА ГМБХ | Фармацевтическая композиция с синергетическим противосудорожным эффектом |
| EP2051735B1 (en) * | 2006-07-17 | 2012-08-29 | Ramot, at Tel Aviv University Ltd. | Conjugates comprising a psychotropic drug or a gaba agonist and an organic acid and their use treating pain and other cns disorders |
| GB0700773D0 (en) | 2007-01-15 | 2007-02-21 | Portela & Ca Sa | Drug therapies |
| WO2008095221A1 (en) | 2007-02-07 | 2008-08-14 | Gosforth Centre (Holdings) Pty Ltd | Treatment of adhd |
| AU2012201853B2 (en) * | 2007-04-16 | 2013-06-27 | Neurotune Ag | Use of dimiracetam in the treatment of chronic pain |
| ITMI20070770A1 (it) * | 2007-04-16 | 2008-10-17 | Brane Discovery S R L | Impiego di dimiracetam nel trattamento del dolore cronico |
| WO2009101616A1 (en) | 2008-02-11 | 2009-08-20 | Ramot At Tel Aviv University Ltd. | Novel conjugates for treating neurodegenerative diseases and disorders |
| EP2331088A4 (en) | 2008-08-06 | 2011-10-12 | Gosforth Ct Holdings Pty Ltd | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC ILLNESSES |
| DK3260118T3 (da) | 2008-10-16 | 2021-04-19 | Univ Johns Hopkins | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| PL389364A1 (pl) * | 2009-10-23 | 2011-04-26 | Uniwersytet Jagielloński | Nowe zastosowanie pochodnych 2-pirolidonu |
| US8377929B2 (en) | 2010-02-24 | 2013-02-19 | Ramot At Tel-Aviv University Ltd. | Crystalline forms of the tri-mesylate salt of perphenazine-GABA and process of producing the same |
| US8822539B2 (en) * | 2010-03-28 | 2014-09-02 | Children's Medical Center Corporation | Combination therapies: inhibitors of GABA transaminase and NKCC1 |
| WO2012038963A1 (en) | 2010-09-22 | 2012-03-29 | Ramot At Tel-Aviv University Ltd. | An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same |
| US20140206667A1 (en) * | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| AU2018208662B2 (en) * | 2012-11-14 | 2020-07-23 | The Johns Hopkins University | Methods and Compositions for Treating Schizophrenia |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| KR101690175B1 (ko) * | 2013-07-02 | 2016-12-27 | 경희대학교 산학협력단 | 고본 추출물을 유효성분으로 포함하는 불면증의 예방 또는 치료용 약학적 조성물 |
| RU2538724C1 (ru) * | 2013-12-19 | 2015-01-10 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Способ лечения эпилепсии |
| KR20220049612A (ko) | 2014-01-21 | 2022-04-21 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| HUE053734T2 (hu) | 2014-01-21 | 2021-07-28 | Janssen Pharmaceutica Nv | 2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait tartalmazó kombinációk és alkalmazásuk |
| RU2563124C1 (ru) * | 2014-04-28 | 2015-09-20 | Федеральное государственное бюджетное учреждение "Федеральный медицинский исследовательский центр психиатрии и наркологии имени В.П. Сербского" Министерства здравоохранения Российской Федерации (ФГБУ "ФМИЦПН им. В.П. Сербского" Минздрава России) | Способ диагностики шизофрении |
| CA2986598C (en) | 2015-05-22 | 2023-09-26 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| ES2972849T3 (es) | 2016-10-14 | 2024-06-17 | Cns Biosciences Inc | Tratamiento del dolor neuropático en personas con lesión de la médula espinal |
| PL244071B1 (pl) * | 2019-01-07 | 2023-11-27 | Univ Jagiellonski | Pochodne (2,5-dioksopirolidyn-1-ylo)(fenylo)-acetamidu i ich zastosowanie do leczenia chorób o podłożu neurologicznym |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8412357D0 (en) | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
| GB8827389D0 (en) | 1988-11-23 | 1988-12-29 | Ucb Sa | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| EP0408782A1 (en) | 1989-07-18 | 1991-01-23 | Nauchnoissledovatelski Chimikopharmatzevtichen Institut | Antihypoxic agent |
| GB9319732D0 (en) | 1993-09-24 | 1993-11-10 | Ucb Sa | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
| US5998380A (en) * | 1995-10-13 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Treatment of migraine |
| CN1131855C (zh) | 1997-12-16 | 2003-12-24 | 沃尼尔·朗伯公司 | 1-取代-1-氨基甲基-环烷衍生物(=加巴喷丁类似物)、其制备及其在治疗神经病方面的用途 |
| CA2309354A1 (en) | 1998-01-23 | 1999-07-29 | Leslie Magnus-Miller | Gabapentin and its derivatives for the treatment of muscular and skeletal pain |
| DE19820381B4 (de) * | 1998-05-07 | 2007-01-25 | Trw Fahrwerksysteme Gmbh & Co Kg | Verfahren zur Beeinflussung der Ventilkennlinie |
| US6495601B1 (en) | 1998-12-23 | 2002-12-17 | Cytoscan Sciences Llc | Methods and compositions for treating conditions of the central and peripheral nervous systems using non-synaptic mechanisms |
| AU2384500A (en) * | 1998-12-23 | 2000-07-12 | Cytoscan Sciences L.L.C. | Compounds, methods of screening and methods of treatment for central and peripheral nervous system disorders |
| US6465458B1 (en) * | 1999-07-01 | 2002-10-15 | Pharmacia & Upjohn Company | Method of treating or preventing chronic pain with a highly selective norepinephrine reuptake inhibitor |
| AU2003225813A1 (en) * | 2002-03-18 | 2003-10-08 | Roger K. Cady | Preemptive prophylaxis of migraine |
| US20040116506A1 (en) * | 2002-06-20 | 2004-06-17 | Krusz John Claude | Use of levetiracetam for treating or preventing acute headaches |
| JP2006516390A (ja) * | 2002-12-03 | 2006-07-06 | ユ セ ベ ソシエテ アノニム | 発作、神経系疾患、内分泌障害及びホルモン疾患の治療用薬剤の同定方法 |
-
2000
- 2000-11-27 CA CA002475026A patent/CA2475026A1/en not_active Abandoned
- 2000-11-27 EP EP00977580A patent/EP1244456B1/en not_active Expired - Lifetime
- 2000-11-27 SK SK749-2002A patent/SK7492002A3/sk unknown
- 2000-11-27 HU HU0204023A patent/HUP0204023A3/hu unknown
- 2000-11-27 US US10/148,347 patent/US6903130B1/en not_active Expired - Fee Related
- 2000-11-27 EP EP05019209A patent/EP1600167A3/en not_active Withdrawn
- 2000-11-27 AT AT00977580T patent/ATE361751T1/de not_active IP Right Cessation
- 2000-11-27 EP EP05019212A patent/EP1600169A3/en not_active Withdrawn
- 2000-11-27 CA CA002392879A patent/CA2392879C/en not_active Expired - Fee Related
- 2000-11-27 KR KR1020027006987A patent/KR20030016205A/ko not_active Ceased
- 2000-11-27 CZ CZ20021904A patent/CZ20021904A3/cs unknown
- 2000-11-27 HK HK03104923.1A patent/HK1052647B/zh not_active IP Right Cessation
- 2000-11-27 PL PL00357472A patent/PL357472A1/xx unknown
- 2000-11-27 ES ES00977580T patent/ES2287039T3/es not_active Expired - Lifetime
- 2000-11-27 WO PCT/EP2000/011808 patent/WO2001039779A1/en not_active Ceased
- 2000-11-27 YU YU37602A patent/YU37602A/sh unknown
- 2000-11-27 MX MXPA02005275A patent/MXPA02005275A/es active IP Right Grant
- 2000-11-27 AR ARP000106224A patent/AR026610A1/es unknown
- 2000-11-27 AU AU15241/01A patent/AU773418B2/en not_active Ceased
- 2000-11-27 TW TW089125114A patent/TWI238062B/zh not_active IP Right Cessation
- 2000-11-27 NZ NZ518901A patent/NZ518901A/en unknown
- 2000-11-27 JP JP2001541511A patent/JP4249415B2/ja not_active Expired - Fee Related
- 2000-11-27 CN CNB008165378A patent/CN100525761C/zh not_active Expired - Fee Related
- 2000-11-27 BR BR0015974-3A patent/BR0015974A/pt not_active Application Discontinuation
- 2000-11-27 EP EP05019211A patent/EP1600168A3/en not_active Withdrawn
- 2000-11-27 RO ROA200200730A patent/RO121085B1/ro unknown
- 2000-11-27 DE DE60034815T patent/DE60034815T2/de not_active Expired - Lifetime
- 2000-11-27 EE EEP200200274A patent/EE200200274A/xx unknown
- 2000-11-27 IL IL14953000A patent/IL149530A0/xx active IP Right Grant
- 2000-11-27 RU RU2002117279/15A patent/RU2261093C2/ru not_active IP Right Cessation
- 2000-11-30 CO CO00091771A patent/CO5261590A1/es not_active Application Discontinuation
- 2000-12-01 MY MYPI20005634A patent/MY127980A/en unknown
-
2001
- 2001-01-20 SA SA01210655A patent/SA01210655B1/ar unknown
-
2002
- 2002-05-08 IL IL149530A patent/IL149530A/en not_active IP Right Cessation
- 2002-05-10 IS IS6377A patent/IS6377A/is unknown
- 2002-05-16 BG BG106708A patent/BG106708A/bg unknown
- 2002-05-31 NO NO20022585A patent/NO20022585L/no not_active Application Discontinuation
-
2005
- 2005-04-21 US US11/111,636 patent/US20050187205A1/en not_active Abandoned
-
2007
- 2007-11-14 JP JP2007295865A patent/JP2008056697A/ja active Pending
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