EP0643706A4 - Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles. - Google Patents
Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles.Info
- Publication number
- EP0643706A4 EP0643706A4 EP19930900600 EP93900600A EP0643706A4 EP 0643706 A4 EP0643706 A4 EP 0643706A4 EP 19930900600 EP19930900600 EP 19930900600 EP 93900600 A EP93900600 A EP 93900600A EP 0643706 A4 EP0643706 A4 EP 0643706A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- bio
- compositions
- particles
- compounds
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1258—Pills, tablets, lozenges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dispersion Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Indole Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79893691A | 1991-11-27 | 1991-11-27 | |
| US798936 | 1991-11-27 | ||
| US07/884,432 US5667764A (en) | 1988-05-02 | 1992-05-15 | Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles |
| US884432 | 1992-05-15 | ||
| PCT/US1992/010076 WO1993011120A1 (en) | 1991-11-27 | 1992-11-24 | Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0643706A4 true EP0643706A4 (en) | 1994-12-27 |
| EP0643706A1 EP0643706A1 (en) | 1995-03-22 |
Family
ID=27122052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP93900600A Withdrawn EP0643706A1 (en) | 1991-11-27 | 1992-11-24 | Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0643706A1 (en) |
| JP (2) | JP3682974B2 (en) |
| CN (1) | CN1074911A (en) |
| AU (2) | AU3221993A (en) |
| CA (1) | CA2124329C (en) |
| IL (1) | IL103874A0 (en) |
| MX (1) | MX9206844A (en) |
| NZ (1) | NZ245271A (en) |
| PH (1) | PH31676A (en) |
| WO (1) | WO1993011120A1 (en) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2472404A1 (en) † | 1993-07-19 | 1995-02-02 | Angiotech Pharmaceuticals, Inc. | Combination of stent and anti-angiogenic factor |
| EP1118325B2 (en) | 1993-07-29 | 2010-01-06 | The United States of America, represented by the Secretary, Department of Health and Human Services | Use of Paclitaxel and its derivatives in the manufacture of a medicament for treating restenosis. |
| US5480901A (en) * | 1994-10-07 | 1996-01-02 | Zynaxis, Inc. | Method for reducing unwanted cellular adhesions |
| US6492332B1 (en) | 1995-12-12 | 2002-12-10 | Omeros Corporation | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation |
| US6004536A (en) * | 1995-11-14 | 1999-12-21 | Molecular Probes, Inc. | Lipophilic cyanine dyes with enchanced aqueous solubilty |
| WO1997024459A1 (en) * | 1995-12-29 | 1997-07-10 | Phanos Technologoes, Inc. | Method for reducing unwanted cellular adhesions |
| US5871436A (en) * | 1996-07-19 | 1999-02-16 | Advanced Cardiovascular Systems, Inc. | Radiation therapy method and device |
| US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US6515016B2 (en) | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
| WO1998043618A2 (en) * | 1997-03-31 | 1998-10-08 | Neorx Corporation | Use of cytoskeletal inhibitors for the prevention of restenosis |
| US7208011B2 (en) | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
| US20040254635A1 (en) | 1998-03-30 | 2004-12-16 | Shanley John F. | Expandable medical device for delivery of beneficial agent |
| US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US6241762B1 (en) | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
| US7045305B1 (en) * | 1998-04-08 | 2006-05-16 | The Regents Of The University Of California | Methods and reagents for targeting organic compounds to selected cellular locations |
| WO1999055396A1 (en) | 1998-04-27 | 1999-11-04 | Surmodics, Inc. | Bioactive agent release coating |
| US6120847A (en) * | 1999-01-08 | 2000-09-19 | Scimed Life Systems, Inc. | Surface treatment method for stent coating |
| US6333347B1 (en) | 1999-01-29 | 2001-12-25 | Angiotech Pharmaceuticals & Advanced Research Tech | Intrapericardial delivery of anti-microtubule agents |
| US6419692B1 (en) | 1999-02-03 | 2002-07-16 | Scimed Life Systems, Inc. | Surface protection method for stents and balloon catheters for drug delivery |
| US6156373A (en) | 1999-05-03 | 2000-12-05 | Scimed Life Systems, Inc. | Medical device coating methods and devices |
| MXPA02001902A (en) * | 1999-08-23 | 2003-04-10 | Angiogene Inc | Radioactively coated device and method of making same for preventing restenosis. |
| CO5261573A1 (en) | 1999-11-19 | 2003-03-31 | Novartis Ag | DERIVATIVES OF BENZOXA AND BEZOTIAZOL, COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM AND PROCESS FOR THE PREPARATION OF THE MENTIONED COMPOSITION |
| IT1319168B1 (en) * | 2000-03-17 | 2003-09-26 | Indena Spa | ANTI-CANCER CONDENSATION DERIVATIVES, THEIR METHOD OF PREPARATION AND FORMULATIONS CONTAINING THEM. |
| DE60133053T2 (en) | 2000-10-16 | 2009-02-26 | Conor Medsystems, Inc., Menlo Park | Expandable medical device for delivering a beneficial agent |
| DE10115740A1 (en) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Preparation for restenosis prophylaxis |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| US7056338B2 (en) | 2003-03-28 | 2006-06-06 | Conor Medsystems, Inc. | Therapeutic agent delivery device with controlled therapeutic agent release rates |
| DE10244847A1 (en) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medical device for drug delivery |
| US7776529B2 (en) | 2003-12-05 | 2010-08-17 | Life Technologies Corporation | Methine-substituted cyanine dye compounds |
| JP2007532187A (en) | 2004-04-06 | 2007-11-15 | サーモディクス，インコーポレイティド | Coating composition for bioactive substances |
| USD516723S1 (en) | 2004-07-06 | 2006-03-07 | Conor Medsystems, Inc. | Stent wall structure |
| DE602005025911D1 (en) | 2004-11-22 | 2011-02-24 | Ge Healthcare As | CONTRASTANT FOR AN EXTRA-CELLULAR MATRIX |
| US9050393B2 (en) | 2005-02-08 | 2015-06-09 | Bruce N. Saffran | Medical devices and methods for modulation of physiology using device-based surface chemistry |
| JP5306811B2 (en) | 2005-05-11 | 2013-10-02 | ライフ テクノロジーズ コーポレーション | Fluorescent chemicals with high selectivity to double-stranded DNA and their use |
| US9198968B2 (en) | 2008-09-15 | 2015-12-01 | The Spectranetics Corporation | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8257722B2 (en) | 2008-09-15 | 2012-09-04 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8114429B2 (en) | 2008-09-15 | 2012-02-14 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
| CN105745266B (en) * | 2013-11-26 | 2019-05-17 | 住友化学株式会社 | Rubber composition and vulcanization aid |
| US10525171B2 (en) | 2014-01-24 | 2020-01-07 | The Spectranetics Corporation | Coatings for medical devices |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| ES2814555T3 (en) | 2016-11-28 | 2021-03-29 | Bayer Pharma AG | Gadolinium chelate compounds with high relaxivity for use in magnetic resonance imaging |
| KR102934987B1 (en) | 2018-11-23 | 2026-03-09 | 바이엘 악티엔게젤샤프트 | Formulation of contrast medium and method for producing same |
| JP7423888B2 (en) * | 2019-11-22 | 2024-01-30 | 株式会社同仁化学研究所 | Dye for staining lipid bilayer membranes and method for staining lipid bilayer membranes using the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
| EP0047470B1 (en) * | 1980-09-02 | 1985-04-24 | Fuji Photo Film Co., Ltd. | Method for immunochemical measurement |
| US4501728A (en) * | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4751219A (en) * | 1985-02-05 | 1988-06-14 | Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek | Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides |
| US4783401A (en) * | 1986-10-31 | 1988-11-08 | Smithkline Beckman Corporation | Viable cell labelling |
| US4762701A (en) * | 1986-10-31 | 1988-08-09 | Smithkline Beckman Corporation | In vivo cellular tracking |
| US4906749A (en) * | 1987-06-30 | 1990-03-06 | Viomedics Inc. | Cyclic anhydride derivatives of chromophors |
| EP0396626A1 (en) * | 1988-01-19 | 1990-11-14 | Board Of Regents, The University Of Texas System | Glycosides, liposomal compositions thereof, and methods for their use |
| ATE145337T1 (en) * | 1988-05-02 | 1996-12-15 | Phanos Tech Inc | COMPOUNDS, COMPOSITIONS AND METHODS FOR BONDING BIO-AFFECTION SUBSTANCES TO SURFACE MEMBRANES OF BIO-PARTICLES |
| US5149794A (en) * | 1990-11-01 | 1992-09-22 | State Of Oregon | Covalent lipid-drug conjugates for drug targeting |
-
1992
- 1992-11-24 EP EP93900600A patent/EP0643706A1/en not_active Withdrawn
- 1992-11-24 AU AU32219/93A patent/AU3221993A/en not_active Abandoned
- 1992-11-24 JP JP51019093A patent/JP3682974B2/en not_active Expired - Lifetime
- 1992-11-24 WO PCT/US1992/010076 patent/WO1993011120A1/en not_active Ceased
- 1992-11-24 CA CA002124329A patent/CA2124329C/en not_active Expired - Lifetime
- 1992-11-25 NZ NZ245271A patent/NZ245271A/en unknown
- 1992-11-25 IL IL103874A patent/IL103874A0/en unknown
- 1992-11-26 PH PH45327A patent/PH31676A/en unknown
- 1992-11-26 CN CN92115176A patent/CN1074911A/en active Pending
- 1992-11-27 MX MX9206844A patent/MX9206844A/en unknown
-
1997
- 1997-04-30 AU AU19914/97A patent/AU1991497A/en not_active Abandoned
-
2002
- 2002-07-01 JP JP2002192417A patent/JP4095847B2/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| No further relevant documents disclosed * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL103874A0 (en) | 1993-04-04 |
| CA2124329C (en) | 2008-11-18 |
| NZ245271A (en) | 1996-03-26 |
| CA2124329A1 (en) | 1993-06-10 |
| CN1074911A (en) | 1993-08-04 |
| JP3682974B2 (en) | 2005-08-17 |
| EP0643706A1 (en) | 1995-03-22 |
| MX9206844A (en) | 1993-07-01 |
| JP4095847B2 (en) | 2008-06-04 |
| AU1991497A (en) | 1997-07-10 |
| AU3221993A (en) | 1993-06-28 |
| WO1993011120A1 (en) | 1993-06-10 |
| JPH08502719A (en) | 1996-03-26 |
| JP2003026657A (en) | 2003-01-29 |
| PH31676A (en) | 1999-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A4 | Supplementary search report drawn up and despatched | ||
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB IE IT LI LU NL SE |
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| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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| 17P | Request for examination filed |
Effective date: 19940617 |
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| AK | Designated contracting states |
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| 17Q | First examination report despatched |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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| 18D | Application deemed to be withdrawn |
Effective date: 19980328 |