EP0663839A4 - COMBINATIONS OF IBUPROFEN WITH A H2 ANTAGONIST. - Google Patents

COMBINATIONS OF IBUPROFEN WITH A H2 ANTAGONIST.

Info

Publication number: EP0663839A4
Authority: EP; European Patent Office
Prior art keywords: ibuprofen; antagonist; combinations
Prior art date: 1992-09-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93921709A

Other languages

German (de)

French (fr)

Other versions

EP0663839A1 (en

Inventor

Robert T Sims

William Slivka

Thomas N Gates

Robert Mcmahon

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kenvue Brands LLC

Merck and Co Inc

Original Assignee

McNeil PPC Inc

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-29

Filing date

1993-09-21

Publication date

1998-06-03

1993-09-21 Application filed by McNeil PPC Inc, Merck and Co Inc filed Critical McNeil PPC Inc

1995-07-26 Publication of EP0663839A1 publication Critical patent/EP0663839A1/en

1998-06-03 Publication of EP0663839A4 publication Critical patent/EP0663839A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP93921709A 1992-09-29 1993-09-21 COMBINATIONS OF IBUPROFEN WITH A H2 ANTAGONIST. Withdrawn EP0663839A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US95344092A	1992-09-29	1992-09-29
US953440		1992-09-29
PCT/US1993/008947 WO1994007541A1 (en)	1992-09-29	1993-09-21	Ibuprofen-h2 antagonist combinations

Publications (2)

Publication Number	Publication Date
EP0663839A1 EP0663839A1 (en)	1995-07-26
EP0663839A4 true EP0663839A4 (en)	1998-06-03

Family

ID=25493996

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93921709A Withdrawn EP0663839A4 (en)	1992-09-29	1993-09-21	COMBINATIONS OF IBUPROFEN WITH A H2 ANTAGONIST.

Country Status (6)

Country	Link
EP (1)	EP0663839A4 (en)
JP (1)	JPH08502254A (en)
AU (1)	AU4931693A (en)
CA (1)	CA2144155A1 (en)
MX (1)	MX9306006A (en)
WO (1)	WO1994007541A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU772188B2 (en)	1998-11-17	2004-04-08	Nitromed, Inc.	Nitrosated and nitrosylated H2 receptor antagonist compounds, compositions and methods of use
SE0000774D0 (en)	2000-03-08	2000-03-08	Astrazeneca Ab	New formulation
EP2260837A1 (en)	2001-06-01	2010-12-15	Pozen, Inc.	Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8206741B2 (en)	2001-06-01	2012-06-26	Pozen Inc.	Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (en)	2001-09-07	2001-09-07	Astrazeneca Ab	New self emulsifying drug delivery system
WO2007012019A2 (en)	2005-07-18	2007-01-25	Horizon Therapeutics, Inc.	Medicaments containing famotidine and ibuprofen and administration of same
US8067451B2 (en)	2006-07-18	2011-11-29	Horizon Pharma Usa, Inc.	Methods and medicaments for administration of ibuprofen
US20080020040A1 (en) *	2006-07-18	2008-01-24	Horizon Therapeutics, Inc.	Unit dose form for administration of ibuprofen
US8067033B2 (en)	2007-11-30	2011-11-29	Horizon Pharma Usa, Inc.	Stable compositions of famotidine and ibuprofen
ES2380747T3 (en) *	2006-07-18	2012-05-18	Horizon Pharma Usa, Inc.	Methods and medications for administration of ibuprofen
PL2240018T3 (en)	2008-01-04	2017-01-31	Schabar Res Ass Llc	ANTI-PAIN AND ANTI-HISTAMIN AGENT COMPOSITION
BRPI0918492A2 (en)	2008-09-09	2015-12-01	Astrazeneca Ab	use of naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof
EP2445499A4 (en)	2009-06-25	2013-02-27	Astrazeneca Ab	METHOD FOR THE TREATMENT OF A PATIENT AT RISK OF DEVELOPING A ULCERE ASSOCIATED WITH NSAID
UA115139C2 (en)	2011-12-28	2017-09-25	Поузен Інк.	Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
WO2015163832A1 (en) *	2014-04-25	2015-10-29	Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş.	An ibuprofen and famotidine combined composition having improved stability
CA3124579C (en)	2020-07-15	2026-03-31	Schabar Research Associates Llc	Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
EP4181912A1 (en)	2020-07-15	2023-05-24	Schabar Research Associates LLC	Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn
US12514846B2 (en)	2020-07-15	2026-01-06	Schabar Research Associates Llc	Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2105193B (en) *	1981-09-04	1984-09-12	Glaxo Group Ltd	Pharmaceutical compositions containing non-steroidal anti-inflammatory agents
NZ235877A (en) *	1989-11-02	1992-09-25	Mcneil Ppc Inc	Composition comprising acetaminophen or nsaid and an h 1 or h 2 receptor blocker and/or proton pump inhibitor for treating overindulgence
US4994604A (en) *	1990-01-10	1991-02-19	Merck & Co., Inc.	Formation and resolution of ibuprofen lysinate
US5009895A (en) *	1990-02-02	1991-04-23	Merck & Co., Inc.	Sustained release with high and low viscosity HPMC

1993
- 1993-09-21 CA CA002144155A patent/CA2144155A1/en not_active Abandoned
- 1993-09-21 EP EP93921709A patent/EP0663839A4/en not_active Withdrawn
- 1993-09-21 WO PCT/US1993/008947 patent/WO1994007541A1/en not_active Ceased
- 1993-09-21 AU AU49316/93A patent/AU4931693A/en not_active Abandoned
- 1993-09-21 JP JP6509138A patent/JPH08502254A/en active Pending
- 1993-09-28 MX MX9306006A patent/MX9306006A/en unknown

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9407541A1 *

Also Published As

Publication number	Publication date
WO1994007541A1 (en)	1994-04-14
MX9306006A (en)	1995-01-31
JPH08502254A (en)	1996-03-12
EP0663839A1 (en)	1995-07-26
CA2144155A1 (en)	1994-04-14
AU4931693A (en)	1994-04-26

Legal Events

Date	Code	Title	Description
1995-06-09	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-07-26	17P	Request for examination filed	Effective date: 19950502
1995-07-26	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1998-06-03	A4	Supplementary search report drawn up and despatched	Effective date: 19980421
1998-06-03	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1998-10-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1998-12-09	18D	Application deemed to be withdrawn	Effective date: 19980710
1998-12-16	RA4	Supplementary search report drawn up and despatched (corrected)	Effective date: 19981028

Publication	Publication Date	Title
EP0663839A4 (en)	1998-06-03	COMBINATIONS OF IBUPROFEN WITH A H2 ANTAGONIST.
DE69229069D1 (en)	1999-06-10	Telephone connection with a close seller
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DE4493840T1 (en)	1996-04-25	Catheter arrangement with a catheter
PT90966A (en)	1989-12-29	PROFILED FACTS
DE68920688D1 (en)	1995-03-02	Anti-growth coating.
ES291766Y (en)	1987-07-16	A STRATIFIED ARTICLE.
DE3881301D1 (en)	1993-07-01	FIBER-PROOFED OPTOELECTRONIC CONVERTER.
DE68904679D1 (en)	1993-03-18	ELECTROPLATING SMALL PARTICLES.
DE69027892D1 (en)	1996-08-29	D / A converter with segment arrangement
DE69328626D1 (en)	2000-06-15	PHOTOCOPYER WITH CODING FUNCTION
DE59300389D1 (en)	1995-08-31	Cathode with a solid element.
NO891757L (en)	1989-11-03	Acrylic polymers.
ATA130593A (en)	1996-05-15	DRAWER WITH A CONNECTING FITTING
DE68905055D1 (en)	1993-04-08	BINAER-TERNAER CONVERTER FOR COMBINING TWO BINAER SIGNALS.
NO943221D0 (en)	1994-08-31	polymerisation
DE68911649D1 (en)	1994-02-03	Joining metallic surfaces.
DE69720007D1 (en)	2003-04-24	BUCKLE USED WITH A GARDEN PRAMER
DE59404378D1 (en)	1997-11-27	Electroacoustic transducer with a terminating part
DE68910414D1 (en)	1993-12-09	Two tone paint film.
DE69413713D1 (en)	1998-11-05	COATING AGENTS WITH A HIGH SOLIDS PART
DE69324681D1 (en)	1999-06-02	DE-PROTEINIZATION WITH AZLACTON-COUPLED FUNCTIONALIZERS
DE68910219D1 (en)	1993-12-02	Angle converter.
DE69408529D1 (en)	1998-03-19	CONTAINER WITH A CHILD-LOCKED, MUG-LOCK