EP0675718A4 - Substituted pyridyl compounds useful as leukotriene antagonists. - Google Patents

Substituted pyridyl compounds useful as leukotriene antagonists.

Info

Publication number: EP0675718A4
Authority: EP; European Patent Office
Prior art keywords: compounds useful; substituted pyridyl; leukotriene antagonists; pyridyl compounds; leukotriene
Prior art date: 1992-12-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19940904523

Other languages

German (de)

French (fr)

Other versions

EP0675718A1 (en

Inventor

Robert A Daines

Israil Pendrak

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-23

Filing date

1993-12-21

Publication date

1995-08-22

1993-12-21 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1995-08-22 Publication of EP0675718A4 publication Critical patent/EP0675718A4/en

1995-10-11 Publication of EP0675718A1 publication Critical patent/EP0675718A1/en

Status Withdrawn legal-status Critical Current

Links

239000003199 leukotriene receptor blocking agent Substances 0.000 title 1
125000004076 pyridyl group Chemical group 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP94904523A 1992-12-23 1993-12-21 Substituted pyridyl compounds useful as leukotriene antagonists Withdrawn EP0675718A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US99621992A	1992-12-23	1992-12-23
US996219		1992-12-23
PCT/US1993/012518 WO1994014442A1 (en)	1992-12-23	1993-12-21	Substituted pyridyl compounds useful as leukotriene antagonists

Publications (2)

Publication Number	Publication Date
EP0675718A4 true EP0675718A4 (en)	1995-08-22
EP0675718A1 EP0675718A1 (en)	1995-10-11

Family

ID=25542633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94904523A Withdrawn EP0675718A1 (en)	1992-12-23	1993-12-21	Substituted pyridyl compounds useful as leukotriene antagonists

Country Status (3)

Country	Link
EP (1)	EP0675718A1 (en)
JP (1)	JPH08505148A (en)
WO (1)	WO1994014442A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991018880A1 (en) *	1990-06-07	1991-12-12	Smithkline Beecham Corporation	Benzoic acid derivatives for treating leukotriene-related diseases
WO1993010780A1 (en) *	1991-12-06	1993-06-10	Smithkline Beecham Corporation	Heterocyclic-substituted pyridine compounds and uses
WO1993011768A1 (en) *	1991-12-13	1993-06-24	Smithkline Beecham Corporation	Pyridyl compounds for psoriasis treatment

1993
- 1993-12-21 WO PCT/US1993/012518 patent/WO1994014442A1/en not_active Ceased
- 1993-12-21 EP EP94904523A patent/EP0675718A1/en not_active Withdrawn
- 1993-12-21 JP JP6515430A patent/JPH08505148A/en active Pending

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991018880A1 (en) *	1990-06-07	1991-12-12	Smithkline Beecham Corporation	Benzoic acid derivatives for treating leukotriene-related diseases
WO1993010780A1 (en) *	1991-12-06	1993-06-10	Smithkline Beecham Corporation	Heterocyclic-substituted pyridine compounds and uses
WO1993011768A1 (en) *	1991-12-13	1993-06-24	Smithkline Beecham Corporation	Pyridyl compounds for psoriasis treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9414442A1 *

Also Published As

Publication number	Publication date
EP0675718A1 (en)	1995-10-11
WO1994014442A1 (en)	1994-07-07
JPH08505148A (en)	1996-06-04

Legal Events

Date	Code	Title	Description
1995-08-22	A4	Supplementary search report drawn up and despatched
1995-08-22	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): BE CH DE FR GB IT LI NL
1995-08-25	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-10-11	17P	Request for examination filed	Effective date: 19950705
1995-10-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE CH DE FR GB IT LI NL
1997-11-07	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1997-12-29	18D	Application deemed to be withdrawn	Effective date: 19970701

Publication	Publication Date	Title
GR3030794T3 (en)	1999-11-30	Substituted thiazolidinedione derivatives.
PH31071A (en)	1998-02-05	Substituted pyrridopyrimidines useful antgiotensinII antagonists.
EP0624159A4 (en)	1995-04-12	Pyridyl substituted imidazoles.
AU3122793A (en)	1993-05-21	Substituted heterocycles as angiotensin ii antagonists
GR3030668T3 (en)	1999-10-29	Condensed indole derivatives as 5ht 4?-receptor antagonists.
GB9405803D0 (en)	1994-05-11	Heteroaromatic compounds
ZA92908B (en)	1993-08-09	Compounds.
SG65570A1 (en)	1999-06-22	Heterobicyclic compounds
AU639611B2 (en)	1993-07-29	Saturated hydroxyalkylquinoline acids as leukotriene antagonists
EP0633771A4 (en)	1995-02-22	Compounds.
ZA929517B (en)	1993-07-12	Compounds.
EP0666851A4 (en)	1995-08-30	Substituted phthalazinones as nerotensin antagonists.
ZA911111B (en)	1992-10-28	Leukotriene antagonists
HU9601772D0 (en)	1996-09-30	Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists
EP0662834A4 (en)	1996-04-17	Novel epoxide-containing compounds.
ZA94891B (en)	1995-08-10	Heteroaromatic compounds
ZA917666B (en)	1993-03-25	Heterocyclic compounds.
GB2264115B (en)	1995-12-20	1H-2-Methylimidazo(4,5-c)pyridinyl Derivatives as PAF Antagonists
EP0546449A3 (en)	1993-07-14	Benzofuranderivatives as angiotensin ii antagonists
HU9402436D0 (en)	1994-10-28	2,6-method-2h-quinolizin derivative as 5-ht3-receptor antagonist
EP0675718A4 (en)	1995-08-22	Substituted pyridyl compounds useful as leukotriene antagonists.
GR3033237T3 (en)	2000-09-29	Quinoline derivatives as leukoriene antagonists.
ZA929462B (en)	1993-10-13	Heterocycle-substituted pyridine compounds useful as leukotriene antagonists
OA09552A (en)	1993-01-31	Heterocyclic compounds.
AU4226493A (en)	1993-11-29	Leukotriene antagonists