EP0708639A4 - METHODS AND COMPOSITIONS FOR TREATING DEPRESSION AND OTHER CONDITIONS WITH OPTICALLY PURE SIBUTRAMINE (+) - Google Patents

METHODS AND COMPOSITIONS FOR TREATING DEPRESSION AND OTHER CONDITIONS WITH OPTICALLY PURE SIBUTRAMINE (+)

Info

Publication number
EP0708639A4
EP0708639A4 EP93915449A EP93915449A EP0708639A4 EP 0708639 A4 EP0708639 A4 EP 0708639A4 EP 93915449 A EP93915449 A EP 93915449A EP 93915449 A EP93915449 A EP 93915449A EP 0708639 A4 EP0708639 A4 EP 0708639A4
Authority
EP
European Patent Office
Prior art keywords
compositions
conditions
methods
optically pure
treating depression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93915449A
Other languages
German (de)
French (fr)
Other versions
EP0708639A1 (en
Inventor
James W Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma America Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of EP0708639A1 publication Critical patent/EP0708639A1/en
Publication of EP0708639A4 publication Critical patent/EP0708639A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP93915449A 1992-06-23 1993-06-22 METHODS AND COMPOSITIONS FOR TREATING DEPRESSION AND OTHER CONDITIONS WITH OPTICALLY PURE SIBUTRAMINE (+) Withdrawn EP0708639A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90303492A 1992-06-23 1992-06-23
US903034 1992-06-23
PCT/US1993/005967 WO1994000047A1 (en) 1992-06-23 1993-06-22 Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine

Publications (2)

Publication Number Publication Date
EP0708639A1 EP0708639A1 (en) 1996-05-01
EP0708639A4 true EP0708639A4 (en) 1997-08-20

Family

ID=25416828

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93915449A Withdrawn EP0708639A4 (en) 1992-06-23 1993-06-22 METHODS AND COMPOSITIONS FOR TREATING DEPRESSION AND OTHER CONDITIONS WITH OPTICALLY PURE SIBUTRAMINE (+)

Country Status (5)

Country Link
EP (1) EP0708639A4 (en)
JP (1) JPH07508281A (en)
AU (1) AU4542993A (en)
CA (1) CA2139000A1 (en)
WO (1) WO1994000047A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020006964A1 (en) * 1995-05-16 2002-01-17 Young James W. Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds
DE19518988A1 (en) * 1995-05-29 1996-12-05 Basf Ag Use of aryl substituted cyclobutylalkylamines to treat obesity
GB9619962D0 (en) * 1996-09-25 1996-11-13 Knoll Ag Medical treatment
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6046242A (en) * 1998-11-27 2000-04-04 Basf Aktiengesellschaft Use of aryl-substituted cyclobutylalkylamines for treating urinary incontinence
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
US6323242B1 (en) 1998-12-02 2001-11-27 Peter Sterling Mueller Treatment of disorders secondary to organic impairments
US6696495B2 (en) 1998-12-02 2004-02-24 Snowden Pharmaceuticals, Llc Treatment of disorders secondary to organic impairments
IL145238A0 (en) * 1999-03-19 2002-06-30 Knoll Gmbh Treatment of osteoarthritis
DE60039132D1 (en) 1999-04-06 2008-07-17 Sepracor Inc O-desmethylvenlafaxine succinate
RU2238084C2 (en) * 1999-08-11 2004-10-20 Сепракор Инк. Compositions comprising inhibitors of dopamine re-uptake and methods for their using
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US20020115727A1 (en) * 2000-12-04 2002-08-22 Senanayake Chris H. Synthesis, methods of using, and compositions of hydroxylated cyclobutylalkylamines
EP1864967A1 (en) 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3008993A1 (en) * 1980-03-08 1981-10-01 Röhm Pharma GmbH, 6100 Darmstadt PHARMACEUTICAL PREPARATIONS
GB2098601B (en) * 1981-04-02 1985-07-24 Sandoz Products Ltd Improvements in or relating to organic compounds
ZA821577B (en) * 1981-04-06 1983-03-30 Boots Co Plc Therapeutic agents
GB8531071D0 (en) * 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
JP2675573B2 (en) * 1988-03-31 1997-11-12 科研製薬株式会社 Brain function improver

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9400047A1 *

Also Published As

Publication number Publication date
JPH07508281A (en) 1995-09-14
EP0708639A1 (en) 1996-05-01
AU4542993A (en) 1994-01-24
WO1994000047A1 (en) 1994-01-06
CA2139000A1 (en) 1994-01-06

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Legal Events

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Owner name: SEPRACOR INC.

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Effective date: 20050101