EP0716694A4 - USE OF THE HUMAN HORMONE GLUCAGON AS A PEPTIDE RECEPTOR 1 - Google Patents

USE OF THE HUMAN HORMONE GLUCAGON AS A PEPTIDE RECEPTOR 1

Info

Publication number
EP0716694A4
EP0716694A4 EP94925207A EP94925207A EP0716694A4 EP 0716694 A4 EP0716694 A4 EP 0716694A4 EP 94925207 A EP94925207 A EP 94925207A EP 94925207 A EP94925207 A EP 94925207A EP 0716694 A4 EP0716694 A4 EP 0716694A4
Authority
EP
European Patent Office
Prior art keywords
peptide receptor
human hormone
hormone glucagon
glucagon
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94925207A
Other languages
German (de)
French (fr)
Other versions
EP0716694A1 (en
Inventor
Michael P Graziano
Doreen A Borkowski
Gary G Chicchi
Patricia J Hey
Catherine D Strader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0716694A1 publication Critical patent/EP0716694A1/en
Publication of EP0716694A4 publication Critical patent/EP0716694A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP94925207A 1993-08-09 1994-08-03 USE OF THE HUMAN HORMONE GLUCAGON AS A PEPTIDE RECEPTOR 1 Withdrawn EP0716694A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10451793A 1993-08-09 1993-08-09
US104517 1993-08-09
PCT/US1994/008913 WO1995004821A1 (en) 1993-08-09 1994-08-03 Human glucagon-like 1 peptide receptor

Publications (2)

Publication Number Publication Date
EP0716694A1 EP0716694A1 (en) 1996-06-19
EP0716694A4 true EP0716694A4 (en) 1997-06-04

Family

ID=22300913

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94925207A Withdrawn EP0716694A4 (en) 1993-08-09 1994-08-03 USE OF THE HUMAN HORMONE GLUCAGON AS A PEPTIDE RECEPTOR 1

Country Status (4)

Country Link
EP (1) EP0716694A4 (en)
JP (1) JPH09501054A (en)
CA (1) CA2168448A1 (en)
WO (1) WO1995004821A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889167A (en) * 1996-05-22 1999-03-30 Merck & Co., Inc. Synthetic glucagon binding proteins
WO1997044357A1 (en) * 1996-05-22 1997-11-27 Merck & Co., Inc. Synthetic glucagon binding proteins
ATE358682T1 (en) * 1996-12-13 2007-04-15 Allelix Biopharma CLONED RECEPTORS OF GLUCAGON-LIKE PEPTIDE-2
US8592553B2 (en) 1996-12-13 2013-11-26 Nps Pharmaceuticals, Inc. Cloned glucagon-like peptide-2 receptors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019175A1 (en) * 1992-03-25 1993-09-30 Bernard Thorens Receptor for the glucagon-like-peptide-1 (glp-1)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019175A1 (en) * 1992-03-25 1993-09-30 Bernard Thorens Receptor for the glucagon-like-peptide-1 (glp-1)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GRAZIANO MP ET AL: "Cloning and functional expression of a human glucagon-like peptide-1 receptor.", BIOCHEM BIOPHYS RES COMMUN, OCT 15 1993, 196 (1) P141-6, UNITED STATES, XP002028256 *
See also references of WO9504821A1 *

Also Published As

Publication number Publication date
WO1995004821A1 (en) 1995-02-16
CA2168448A1 (en) 1995-02-16
EP0716694A1 (en) 1996-06-19
JPH09501054A (en) 1997-02-04

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Legal Events

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