EP0730466A4 - COMPOSITIONS AND METHODS FOR INHIBITING THE INVASION OF HEPATOCYTES BY MALARIA SPOROZOES - Google Patents

COMPOSITIONS AND METHODS FOR INHIBITING THE INVASION OF HEPATOCYTES BY MALARIA SPOROZOES

Info

Publication number
EP0730466A4
EP0730466A4 EP94928067A EP94928067A EP0730466A4 EP 0730466 A4 EP0730466 A4 EP 0730466A4 EP 94928067 A EP94928067 A EP 94928067A EP 94928067 A EP94928067 A EP 94928067A EP 0730466 A4 EP0730466 A4 EP 0730466A4
Authority
EP
European Patent Office
Prior art keywords
sporozoes
hepatocytes
malaria
invasion
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94928067A
Other languages
German (de)
French (fr)
Other versions
EP0730466A1 (en
Inventor
Carla Cerami
Ute Frevert
Phetori Sinnis
Victor Nussenzweig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University NYU filed Critical New York University NYU
Publication of EP0730466A1 publication Critical patent/EP0730466A1/en
Publication of EP0730466A4 publication Critical patent/EP0730466A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
EP94928067A 1993-09-10 1994-09-09 COMPOSITIONS AND METHODS FOR INHIBITING THE INVASION OF HEPATOCYTES BY MALARIA SPOROZOES Withdrawn EP0730466A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11969493A 1993-09-10 1993-09-10
US119694 1993-09-10
PCT/US1994/010186 WO1995007094A1 (en) 1993-09-10 1994-09-09 Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Publications (2)

Publication Number Publication Date
EP0730466A1 EP0730466A1 (en) 1996-09-11
EP0730466A4 true EP0730466A4 (en) 1999-04-14

Family

ID=22385814

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94928067A Withdrawn EP0730466A4 (en) 1993-09-10 1994-09-09 COMPOSITIONS AND METHODS FOR INHIBITING THE INVASION OF HEPATOCYTES BY MALARIA SPOROZOES

Country Status (4)

Country Link
EP (1) EP0730466A4 (en)
AU (1) AU7724894A (en)
CA (1) CA2171562A1 (en)
WO (1) WO1995007094A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9266930B1 (en) 1993-03-05 2016-02-23 Epimmune Inc. Inducing cellular immune responses to Plasmodium falciparum using peptide and nucleic acid compositions
FR2840220A1 (en) * 2002-05-28 2003-12-05 Univ Paris Curie METHOD FOR THE PROPHYLACTIC TREATMENT OF MALARIA, OR PROCESS FOR THE PREPARATION OF A MEDICAMENT FOR THE PROPHYLACTIC TREATMENT OF MALARIA
BRPI0417762A8 (en) 2003-12-19 2015-12-22 Seattle Biomedical Res Institute LIVE ORGANISMS, A PLASMODIUM, METHOD FOR INOCCULATING A VERTEBRATE HOST AGAINST MALARIA, VACCINE COMPOSITION, USE OF A LIVE ORGANISM, A PLASMODIUM, AND, METHOD OF PRODUCTION OF A VACCINE COMPOSITION
US8168166B2 (en) 2003-12-19 2012-05-01 Seattle Biomedical Research Institute Live genetically attenuated malaria vaccine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0432965A1 (en) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria vaccine
EP0517182A1 (en) * 1991-06-03 1992-12-09 Mitsubishi Chemical Corporation Hepatocyte-growth agent
WO1993002704A1 (en) * 1991-07-31 1993-02-18 Institut Pasteur Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum
WO1993003057A1 (en) * 1991-07-31 1993-02-18 Institut Pasteur Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions
EP0578342A2 (en) * 1992-05-14 1994-01-12 W.R. Grace & Co.-Conn. Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor
WO1994006464A1 (en) * 1992-09-17 1994-03-31 New York University Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0432965A1 (en) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria vaccine
EP0517182A1 (en) * 1991-06-03 1992-12-09 Mitsubishi Chemical Corporation Hepatocyte-growth agent
WO1993002704A1 (en) * 1991-07-31 1993-02-18 Institut Pasteur Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum
WO1993003057A1 (en) * 1991-07-31 1993-02-18 Institut Pasteur Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions
EP0578342A2 (en) * 1992-05-14 1994-01-12 W.R. Grace & Co.-Conn. Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor
WO1994006464A1 (en) * 1992-09-17 1994-03-31 New York University Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CERAMI, CARLA ET AL: "The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites", CELL (CAMBRIDGE, MASS.) (1992), 70(6), 1021-33 CODEN: CELLB5;ISSN: 0092-8674, 1992, XP002090186 *
See also references of WO9507094A1 *
SINNIS, PHOTINI ET AL: "Structural and functional properties of region II-plus of the malaria circumsporozoite protein", J. EXP. MED. (1994), 180(1), 297-306 CODEN: JEMEAV;ISSN: 0022-1007, 1994, XP002090187 *

Also Published As

Publication number Publication date
EP0730466A1 (en) 1996-09-11
AU7724894A (en) 1995-03-27
CA2171562A1 (en) 1995-03-16
WO1995007094A1 (en) 1995-03-16

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