EP0814814A4 - Methodes de traitement de la thrombose - Google Patents

Methodes de traitement de la thrombose

Info

Publication number
EP0814814A4
EP0814814A4 EP95913770A EP95913770A EP0814814A4 EP 0814814 A4 EP0814814 A4 EP 0814814A4 EP 95913770 A EP95913770 A EP 95913770A EP 95913770 A EP95913770 A EP 95913770A EP 0814814 A4 EP0814814 A4 EP 0814814A4
Authority
EP
European Patent Office
Prior art keywords
thrombosis
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95913770A
Other languages
German (de)
English (en)
Other versions
EP0814814A1 (fr
Inventor
Lester R Sauvage
Svetlana Kaplan
Alenxander Kaplan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hope Heart Institute
Original Assignee
Hope Heart Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hope Heart Institute filed Critical Hope Heart Institute
Publication of EP0814814A1 publication Critical patent/EP0814814A1/fr
Publication of EP0814814A4 publication Critical patent/EP0814814A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP95913770A 1993-04-22 1995-03-15 Methodes de traitement de la thrombose Withdrawn EP0814814A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/052,219 US5401730A (en) 1990-07-06 1993-04-22 Method for reducing platelet aggregation
PCT/US1995/003429 WO1996028168A1 (fr) 1993-04-22 1995-03-15 Methodes de traitement de la thrombose

Publications (2)

Publication Number Publication Date
EP0814814A1 EP0814814A1 (fr) 1998-01-07
EP0814814A4 true EP0814814A4 (fr) 1999-01-13

Family

ID=21976172

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95913770A Withdrawn EP0814814A4 (fr) 1993-04-22 1995-03-15 Methodes de traitement de la thrombose

Country Status (5)

Country Link
US (1) US5401730A (fr)
EP (1) EP0814814A4 (fr)
JP (1) JPH11507325A (fr)
AU (1) AU2103295A (fr)
WO (1) WO1996028168A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2162586C (fr) 1993-05-13 2006-01-03 David J. Grainger Prevention et traitement de pathologies associees a la proliferation anormale de cellules de muscle lisse
AU5787996A (en) * 1995-04-19 1996-11-07 Lipoprotein Technologies, Inc. Compositions, kits, and methods for administration of antilipemic and anti-platelet aggregation drugs
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
FR2740335B1 (fr) * 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, de lithium, d'etain, de zinc, de manganese ou d'yttrium comme antagoniste de substance p
US5770215A (en) * 1997-01-06 1998-06-23 Moshyedi; Emil Payman Multivitamin/vascular occlusion inhibiting composition
RU2135185C1 (ru) * 1997-03-11 1999-08-27 Хазанов Вениамин Абрамович Противовоспалительное средство
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6121249A (en) * 1998-07-01 2000-09-19 Donald L. Weissman Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins
US6274170B1 (en) 1999-02-18 2001-08-14 Richard Heibel Compounds for cardiovascular treatment comprising multi-vitamin and anti-platelet aggregating agents and methods for making and using the same
HU9902296D0 (en) * 1999-07-07 1999-10-28 Dardai Pharmaceutical composition for treating caltification
DE19959913A1 (de) * 1999-12-11 2001-06-28 Lohmann Therapie Syst Lts Acetylsalicylsäure enthaltendes transdermales System zur Behandlung von Migräne
US7226916B1 (en) * 2000-05-08 2007-06-05 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
US7208180B2 (en) * 2000-05-08 2007-04-24 N.V. Nutricia Method and preparation for the preventing and/or treating vascular disorders and secondary disorders associated therewith
NZ526540A (en) * 2000-12-25 2004-11-26 Sankyo Co Medicinal compositions containing aspirin and 2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-flurobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine useful in preventing thrombus or embolus diseases
DE10115073A1 (de) * 2001-03-27 2002-10-10 Procorde Gmbh Verwendung von Inhibitoren von IKK-ß und Verfahren zum Auffinden solcher Inhibitoren
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US8975295B2 (en) * 2002-10-25 2015-03-10 Precision Dermatology, Inc. Modulation of zinc levels to improve tissue properties
GB2407040B (en) * 2003-10-15 2007-09-19 Sheikh Arshad Saeed Anti-platelet aggregation compositions
FI20040136A0 (fi) * 2004-01-30 2004-01-30 Faron Pharmaceuticals Oy Erityisesti diabeetikoille soveltuvia koostumuksia
US20090023692A1 (en) * 2005-03-08 2009-01-22 Neursosci, Inc. Compositions for inhibiting and preventing vascular occlusion containing nutritional supplements
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
WO2007089267A1 (fr) 2006-02-03 2007-08-09 Jr Chem, Llc Traitement anti-vieillissement utilisant des préparations de cuivre et de zinc
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
CA2750636C (fr) 2009-01-23 2017-07-25 Jr Chem, Llc Traitements pour l'acne rosacee et trousses medicales pour les mettre en pratique
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0372676A1 (fr) * 1988-12-08 1990-06-13 Spyros Carantinos Préparation thérapeutique et procédé
EP0424706A1 (fr) * 1989-10-25 1991-05-02 Pharmatrans Sanaq Ag Forme galénique à mâcher ou à sucer, procédé pour sa préparation et son utilisation
CN1105237A (zh) * 1994-10-15 1995-07-19 孙素波 阿斯匹林口香糖

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3842169A (en) * 1970-09-14 1974-10-15 H Schneyer Composition and method for treatment of pathological calcification in animals
US3904761A (en) * 1974-01-25 1975-09-09 Hoechst Co American Method of preventing thrombosis
FR2307538A1 (fr) * 1975-04-18 1976-11-12 Centre Etd Ind Pharma Nouveau medicament anti-agregant plaquettaire
DE2549998A1 (de) * 1975-11-07 1977-05-12 Merck Patent Gmbh Mittel zur hemmung der thrombozytenaggregation
US4193813A (en) * 1976-09-07 1980-03-18 Medi-Coll, Inc. Method for making collagen sponge
DE3535947A1 (de) * 1985-10-09 1987-04-09 Basf Ag Kombinationspraeparat
US4845129A (en) * 1988-03-14 1989-07-04 Sandoz Pharm. Corp. Diaryl substituted cyclopentane and cyclopentene derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0372676A1 (fr) * 1988-12-08 1990-06-13 Spyros Carantinos Préparation thérapeutique et procédé
EP0424706A1 (fr) * 1989-10-25 1991-05-02 Pharmatrans Sanaq Ag Forme galénique à mâcher ou à sucer, procédé pour sa préparation et son utilisation
CN1105237A (zh) * 1994-10-15 1995-07-19 孙素波 阿斯匹林口香糖

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 9730, Derwent World Patents Index; Class B05, AN 97-320246, XP002083710 *
GORDON, P. R. ET AL.: "Effect of Acute Zinc Deprivation on Plasma Zinc", NUTRITION, vol. 35, no. 1, 1982, USA, pages 113 - 119, XP002083778 *
KAPLAN S., ET AL.: "Citric Acid Enhances the Antithrombotic Effect of Aspirin in Many Aspirin-resistant Subjects", CLINICAL AND APPLIED THROMBOSIS/ HEMOSTASIS, vol. 3, no. 1, 1997, US, pages 54 - 57, XP002084238 *
See also references of WO9628168A1 *

Also Published As

Publication number Publication date
WO1996028168A1 (fr) 1996-09-19
EP0814814A1 (fr) 1998-01-07
US5401730A (en) 1995-03-28
AU2103295A (en) 1996-10-02
JPH11507325A (ja) 1999-06-29

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Legal Events

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