EP0822980A4 - Recombinant infectious laryngotracheitis virus and uses thereof - Google Patents

Recombinant infectious laryngotracheitis virus and uses thereof

Info

Publication number
EP0822980A4
EP0822980A4 EP96910515A EP96910515A EP0822980A4 EP 0822980 A4 EP0822980 A4 EP 0822980A4 EP 96910515 A EP96910515 A EP 96910515A EP 96910515 A EP96910515 A EP 96910515A EP 0822980 A4 EP0822980 A4 EP 0822980A4
Authority
EP
European Patent Office
Prior art keywords
infectious laryngotracheitis
gene
laryngotracheitis virus
virus
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96910515A
Other languages
German (de)
French (fr)
Other versions
EP0822980A1 (en
Inventor
Martha A Wild
Mark D Cochran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntro Corp
Original Assignee
Syntro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntro Corp filed Critical Syntro Corp
Publication of EP0822980A1 publication Critical patent/EP0822980A1/en
Publication of EP0822980A4 publication Critical patent/EP0822980A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the glycoprotein gG gene. This attenuated virus is useful as a vaccine against infectious laryngotracheitis virus. The present invention also provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the US2 gene, UL47-like gene, ORF4 gene or glycoprotein g60 gene. The present invention also provides a method for distinguishing chickens or other poultry vaccinated with a recombinant infectious laryngotracheitis virus which produces no glycoprotein gG from those infected with a naturally-occuring infectious laryngotracheitis virus.
EP96910515A 1995-03-23 1996-03-21 Recombinant infectious laryngotracheitis virus and uses thereof Withdrawn EP0822980A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US410121 1982-08-20
US41012195A 1995-03-23 1995-03-23
US46819095A 1995-06-06 1995-06-06
US468190 1995-06-06
PCT/US1996/003916 WO1996029396A1 (en) 1995-03-23 1996-03-21 Recombinant infectious laryngotracheitis virus and uses thereof

Publications (2)

Publication Number Publication Date
EP0822980A1 EP0822980A1 (en) 1998-02-11
EP0822980A4 true EP0822980A4 (en) 2000-04-26

Family

ID=27020873

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96910515A Withdrawn EP0822980A4 (en) 1995-03-23 1996-03-21 Recombinant infectious laryngotracheitis virus and uses thereof

Country Status (4)

Country Link
EP (1) EP0822980A4 (en)
JP (1) JP3964458B2 (en)
CA (1) CA2216139C (en)
WO (1) WO1996029396A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8821441D0 (en) 1988-09-13 1988-10-12 Animal Health Inst Viral vectors
FR2750866B1 (en) * 1996-06-27 1998-11-27 Rhone Merieux AVIAN RECOMBINANT LIVING VACCINE USING AVIAN INFECTIOUS LARYNGOTRACHEITIS VIRUS
FR2757061B1 (en) * 1996-12-16 1999-03-26 Rhone Merieux AVIAN RECOMBINANT LIVING VACCINE USING AVIAN INFECTIOUS LARYNGOTRACHEITIS VIRUS AS A VECTOR
AU2003270824B2 (en) 2002-09-18 2009-02-19 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Recovery of recombinant human parainfluenza virus type 2 (HPIV2) from cDNA and use of recombinant HPIV2 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens
EP2768529A1 (en) 2011-10-21 2014-08-27 Intervet International B.V. Recombinant nonpathogenic mdv vector providing multivalent immunity
CN107805631B (en) 2011-10-21 2021-10-01 英特维特国际股份有限公司 Recombinant non-pathogenic Marek's disease virus constructs encoding infectious laryngotracheitis virus and Newcastle disease virus antigens
KR102617503B1 (en) 2016-12-14 2023-12-29 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 Recombinant HVT vectors expressing multiple antigens of avian pathogens and vaccines containing them
CN109609468B (en) * 2018-12-10 2020-06-30 畜科生物工程有限公司 Six-gene-deleted porcine pseudorabies virus, porcine pseudorabies vaccine and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008622A1 (en) * 1993-09-24 1995-03-30 Syntro Corporation Recombinant infectious laryngotracheitis virus and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0434747B1 (en) * 1988-09-13 1999-05-19 Merial RECOMBINANT VACCINES BASED ON THE gB-PROTEIN OF MAREK'S DISEASE VIRUS
WO1991002053A1 (en) * 1989-08-01 1991-02-21 Arthur Webster Pty. Ltd. Low virulence laryngotracheitis (ilt) virus for vaccinating birds
DE69101683T2 (en) * 1990-07-30 1994-07-21 Akzo Nv Recombinant Mareks disease virus.
WO1992003554A1 (en) * 1990-08-24 1992-03-05 Arthur Webster Pty. Ltd. Infectious laryngotracheitis virus vaccine
US6087127A (en) * 1990-08-24 2000-07-11 Board Of Trustees Operating Michigan State University Marek's disease herpesvirus DNA segment encoding glycoproteins, gD, gI and gE

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008622A1 (en) * 1993-09-24 1995-03-30 Syntro Corporation Recombinant infectious laryngotracheitis virus and uses thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GUO P. ET AL.: "Construction of recombinant avian infectious laryngotracheitis virus expressing the beta-galactosidase gene and DNA sequencing of the insertion region", VIROLOGY, vol. 202, 1994, pages 771 - 781, XP002131399 *
KONGUSUWAN K. ET AL.: "Nucleotide sequence analysis of an infectious layngotracheitis virus gene corresponding to the US3 of HSV-1 and a unique gene encoding a 67 kDa protein.", ARCH. VIROL., vol. 140, no. 1, January 1995 (1995-01-01), pages 27 - 39, XP000877135 *
See also references of WO9629396A1 *
WILD M A ET AL: "A GENOMIC MAP OF INFECTIOUS LARYNGOTRACHEITIS VIRUS AND THE SEQUENCE AND ORGANIZATION OF GENES PRESENT IN THE UNIQUE SHORT AND FLANKING REGIONS", VIRUS GENES,US,KLUWER ACADEMIC PUBLISHERS, BOSTON, vol. 12, no. 2, 1 January 1996 (1996-01-01), pages 107 - 116, XP000645840, ISSN: 0920-8569 *
ZELNIK V. ET AL.: "The complete sequence and gene organization of the short unique region of herpesviru of turkeys", J. GEN. VIROL., vol. 74, 1993, pages 2151 - 2162, XP002131400 *

Also Published As

Publication number Publication date
EP0822980A1 (en) 1998-02-11
JP3964458B2 (en) 2007-08-22
CA2216139C (en) 2013-01-08
WO1996029396A1 (en) 1996-09-26
CA2216139A1 (en) 1996-09-26
AU5369096A (en) 1996-10-08
JPH11503009A (en) 1999-03-23
AU721451B2 (en) 2000-07-06

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