EP0855029A4 - HIGH YIELD ASSAY USING FUSION PROTEINS - Google Patents

HIGH YIELD ASSAY USING FUSION PROTEINS

Info

Publication number
EP0855029A4
EP0855029A4 EP96931529A EP96931529A EP0855029A4 EP 0855029 A4 EP0855029 A4 EP 0855029A4 EP 96931529 A EP96931529 A EP 96931529A EP 96931529 A EP96931529 A EP 96931529A EP 0855029 A4 EP0855029 A4 EP 0855029A4
Authority
EP
European Patent Office
Prior art keywords
fusion proteins
high yield
yield assay
assay
fusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96931529A
Other languages
German (de)
French (fr)
Other versions
EP0855029A1 (en
Inventor
Scott P Salowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603486.3A external-priority patent/GB9603486D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0855029A1 publication Critical patent/EP0855029A1/en
Publication of EP0855029A4 publication Critical patent/EP0855029A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
EP96931529A 1995-09-15 1996-09-11 HIGH YIELD ASSAY USING FUSION PROTEINS Withdrawn EP0855029A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US382495P 1995-09-15 1995-09-15
US3824 1995-09-15
GB9603486 1996-02-20
GBGB9603486.3A GB9603486D0 (en) 1996-02-20 1996-02-20 A high throughputassay using fusion proteins
PCT/US1996/014563 WO1997010502A1 (en) 1995-09-15 1996-09-11 A high throughput assay using fusion proteins

Publications (2)

Publication Number Publication Date
EP0855029A1 EP0855029A1 (en) 1998-07-29
EP0855029A4 true EP0855029A4 (en) 2000-03-08

Family

ID=26308762

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96931529A Withdrawn EP0855029A4 (en) 1995-09-15 1996-09-11 HIGH YIELD ASSAY USING FUSION PROTEINS

Country Status (4)

Country Link
EP (1) EP0855029A4 (en)
JP (1) JP2000501171A (en)
CA (1) CA2231385A1 (en)
WO (1) WO1997010502A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
WO1998041866A1 (en) * 1997-03-14 1998-09-24 Merck & Co., Inc. A high throughput assay using fusion proteins
WO1999060504A1 (en) 1998-05-15 1999-11-25 Unicast Communications Corporation A technique for implementing browser-initiated network-distributed advertising and for interstitially displaying an advertisement
EP1144655A2 (en) * 1998-10-19 2001-10-17 Ariad Gene Therapeutics, Inc. Regulated expression using conditional er retention domains
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
DK2267452T3 (en) 2001-06-22 2012-10-29 Hoffmann La Roche Soluble complex comprising a retroviral surface glycoprotein
US20040225077A1 (en) 2002-12-30 2004-11-11 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1892530A1 (en) * 2006-08-25 2008-02-27 Boehringer Ingelheim Pharma GmbH & Co. KG Method for determining transport activity of a transport protein
EP2245165A4 (en) 2008-01-11 2011-06-01 Massachusetts Eye & Ear Infirm Conditional-stop dimerizable caspase transgenic animals
CN105283553B (en) 2013-06-11 2021-06-25 克隆技术实验室有限公司 Protein-enriched microvesicles and methods of making and using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154734A1 (en) * 1984-03-15 1985-09-18 Immunex Corporation Immediate ligand detection assay, a test kit and its formation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154734A1 (en) * 1984-03-15 1985-09-18 Immunex Corporation Immediate ligand detection assay, a test kit and its formation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BANKS, M. ET AL.: "Soluble Interleukin-5 Receptor alpha-Chain Binding Assays: Use for Screening and Analysis of Interleukin-5 Mutants", ANALYTICAL BIOCHEMISTRY, vol. 230, no. 2, 1995, pages 321 - 328, XP002113269 *
See also references of WO9710502A1 *

Also Published As

Publication number Publication date
JP2000501171A (en) 2000-02-02
CA2231385A1 (en) 1997-03-20
EP0855029A1 (en) 1998-07-29
WO1997010502A1 (en) 1997-03-20

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