EP0909163A4 - Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,r)-glycopyrrolate - Google Patents

Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,r)-glycopyrrolate

Info

Publication number
EP0909163A4
EP0909163A4 EP97931548A EP97931548A EP0909163A4 EP 0909163 A4 EP0909163 A4 EP 0909163A4 EP 97931548 A EP97931548 A EP 97931548A EP 97931548 A EP97931548 A EP 97931548A EP 0909163 A4 EP0909163 A4 EP 0909163A4
Authority
EP
European Patent Office
Prior art keywords
glycopyrrolate
compositions
methods
urinary incontinence
enantiomerically enriched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97931548A
Other languages
German (de)
French (fr)
Other versions
EP0909163A1 (en
Inventor
Vincent L Fabiano
John R Mccullough
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma America Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of EP0909163A1 publication Critical patent/EP0909163A1/en
Publication of EP0909163A4 publication Critical patent/EP0909163A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP97931548A 1996-07-01 1997-06-27 Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,r)-glycopyrrolate Withdrawn EP0909163A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2115696P 1996-07-01 1996-07-01
US21156P 1996-07-01
PCT/US1997/011639 WO1998000109A1 (en) 1996-07-01 1997-06-27 Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,r)-glycopyrrolate

Publications (2)

Publication Number Publication Date
EP0909163A1 EP0909163A1 (en) 1999-04-21
EP0909163A4 true EP0909163A4 (en) 1999-06-09

Family

ID=21802667

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97931548A Withdrawn EP0909163A4 (en) 1996-07-01 1997-06-27 Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,r)-glycopyrrolate

Country Status (2)

Country Link
EP (1) EP0909163A4 (en)
WO (1) WO1998000109A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613795B2 (en) 1996-11-11 2003-09-02 Christian Noe Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments
AU2002345266B2 (en) 2002-07-08 2009-07-02 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
AU2002347552A1 (en) 2002-12-23 2004-07-14 Ranbaxy Laboratories Limited 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
EP1618091A1 (en) 2003-04-09 2006-01-25 Ranbaxy Laboratories, Ltd. Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
PL2064453T3 (en) 2006-09-20 2011-09-30 Woodwelding Ag Anchoring in a construction material
PL2205429T3 (en) 2007-10-25 2014-02-28 Woodwelding Ag Method of and device for anchoring a dowel using mechanical vibrations
JO3510B1 (en) * 2011-03-04 2020-07-05 Heptares Therapeutics Ltd Use of glycopyrrolate for treating tachycardia
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
JP6114841B2 (en) 2013-02-28 2017-04-12 ダーミラ, インク.Dermira, Inc. Glycopyrrolate salt
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075312A (en) * 1988-10-27 1991-12-24 Leitman Esther M Novel anti-micturition composition and method
US5525347A (en) * 1995-01-31 1996-06-11 Medical University Of South Carolina Composition and methods for treating performance anxiety

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DANIEL W. ARMSTRONG ET AL.: "Separation of drug stereoisomers by formation of beta-cyclodextrin inclusion complexes", SCIENCE, vol. 232, no. 4754 part 1, 1986, pages 1132 - 1135, XP002099198 *
See also references of WO9800109A1 *

Also Published As

Publication number Publication date
EP0909163A1 (en) 1999-04-21
WO1998000109A1 (en) 1998-01-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19990120

AK Designated contracting states

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Ipc: A61K 31/40

A4 Supplementary search report drawn up and despatched

Effective date: 19990423

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Effective date: 20011030