EP0944394A4 - TREATMENT OF HIV INFECTION BY ACTION ON THE HOST CELL CYCLOPHILIN RECEPTOR - Google Patents

TREATMENT OF HIV INFECTION BY ACTION ON THE HOST CELL CYCLOPHILIN RECEPTOR

Info

Publication number: EP0944394A4
Authority: EP; European Patent Office
Prior art keywords: action; treatment; host cell; hiv infection; cyclophilin receptor
Prior art date: 1996-03-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP97917517A

Other languages

German (de)

French (fr)

Other versions

EP0944394A1 (en

Inventor

Michael Bukrinsky

Barbara A Sherry

Peter C Ulrich

Anthony Cerami

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Picower Institute for Medical Research

Original Assignee

Picower Institute for Medical Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-12

Filing date

1997-03-12

Publication date

2003-05-14

1996-03-14 Priority claimed from US08/615,933 external-priority patent/US5840305A/en

1997-03-12 Application filed by Picower Institute for Medical Research filed Critical Picower Institute for Medical Research

1999-09-29 Publication of EP0944394A1 publication Critical patent/EP0944394A1/en

2003-05-14 Publication of EP0944394A4 publication Critical patent/EP0944394A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/52—Isomerases (5)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oncology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Biochemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP97917517A 1996-03-12 1997-03-12 TREATMENT OF HIV INFECTION BY ACTION ON THE HOST CELL CYCLOPHILIN RECEPTOR Withdrawn EP0944394A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US1318596P	1996-03-12	1996-03-12
US613185P		1996-03-12
US08/615,933 US5840305A (en)	1996-03-14	1996-03-14	Treatment of HIV-Infection by interfering with host cell cyclophilin receptor activity
US615933		1996-03-14
PCT/US1997/003819 WO1997033604A1 (en)	1996-03-12	1997-03-12	Treatment of hiv-infection by interfering with host cell cyclophilin receptor activity

Publications (2)

Publication Number	Publication Date
EP0944394A1 EP0944394A1 (en)	1999-09-29
EP0944394A4 true EP0944394A4 (en)	2003-05-14

Family

ID=26684543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP97917517A Withdrawn EP0944394A4 (en)	1996-03-12	1997-03-12	TREATMENT OF HIV INFECTION BY ACTION ON THE HOST CELL CYCLOPHILIN RECEPTOR

Country Status (5)

Country	Link
EP (1)	EP0944394A4 (en)
JP (1)	JP2000510097A (en)
AU (1)	AU723905B2 (en)
CA (1)	CA2248192A1 (en)
WO (1)	WO1997033604A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
US7141648B2 (en)	2001-10-19	2006-11-28	Isotechnika Inc.	Synthesis of cyclosporin analogs
HRP20040354B1 (en)	2001-10-19	2012-10-31	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
AU2002347102A1 (en) *	2001-10-25	2003-05-12	Hans Will	Means for inhibition of the synthesis of viral proteins
US7108988B2 (en)	2001-11-02	2006-09-19	The J. David Gladstone Institutes	Methods of identifying agents for inhibiting lentivirus replication
US10365280B2 (en)	2014-10-02	2019-07-30	Dana-Farber Cancer Institute, Inc.	Compositions and methods for treating malignancies
ES2990218T3 (en) *	2018-08-22	2024-11-29	Bacainn Biotherapeutics Ltd	Compositions of cyclosporine and methods of use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0484281A2 (en) *	1990-11-02	1992-05-06	Sandoz Ltd.	Cyclosporins
WO1993023081A1 (en) *	1992-05-15	1993-11-25	The Rockefeller University	Methods and agents for modulating immune response, and uses thereof
WO1995007468A1 (en) *	1993-09-08	1995-03-16	Sandoz Ltd.	Assay kit

1997
- 1997-03-12 EP EP97917517A patent/EP0944394A4/en not_active Withdrawn
- 1997-03-12 WO PCT/US1997/003819 patent/WO1997033604A1/en not_active Ceased
- 1997-03-12 AU AU25811/97A patent/AU723905B2/en not_active Ceased
- 1997-03-12 JP JP09532773A patent/JP2000510097A/en not_active Ceased
- 1997-03-12 CA CA002248192A patent/CA2248192A1/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0484281A2 (en) *	1990-11-02	1992-05-06	Sandoz Ltd.	Cyclosporins
WO1993023081A1 (en) *	1992-05-15	1993-11-25	The Rockefeller University	Methods and agents for modulating immune response, and uses thereof
WO1995007468A1 (en) *	1993-09-08	1995-03-16	Sandoz Ltd.	Assay kit

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALLAIN F ET AL: "Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 178, no. 1, 13 January 1995 (1995-01-13), pages 113 - 120, XP004021130, ISSN: 0022-1759 *
BILLICH A ET AL: "MODE OF ACTION OF SDZ NIM 811, A NONIMMUNOSUPPRESSIVE CYCLOSPORIN A ANALOG WITH ACTIVITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 1: INTERFERENCE WITH HIV PROTEIN-CYCLOPHILIN A INTERACTIONS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 69, no. 4, 1 April 1995 (1995-04-01), pages 2451 - 2461, XP002022423, ISSN: 0022-538X *
ROYDON PRICE E ET AL: "CYCLOPHILIN B TRAFFICKING THROUGH THE SECRETORY PATHWAY IS ALTERED BY BINDING OF CYCLOSPORIN A", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, April 1994 (1994-04-01), pages 3931 - 3935, XP002931337, ISSN: 0027-8424 *
See also references of WO9733604A1 *

Also Published As

Publication number	Publication date
JP2000510097A (en)	2000-08-08
AU2581197A (en)	1997-10-01
EP0944394A1 (en)	1999-09-29
AU723905B2 (en)	2000-09-07
CA2248192A1 (en)	1997-09-18
WO1997033604A1 (en)	1997-09-18

Legal Events

Date	Code	Title	Description
1999-08-13	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-09-29	17P	Request for examination filed	Effective date: 19981012
1999-09-29	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2003-05-14	A4	Supplementary search report drawn up and despatched	Effective date: 20030402
2003-05-14	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 39:00 K Ipc: 7A 61K 39/39 K Ipc: 7A 61K 38:13 J Ipc: 7A 61K 47/48 J Ipc: 7A 61K 47/48 B Ipc: 7C 12N 9/90 B Ipc: 7A 61K 39/39 B Ipc: 7A 61K 39/395 B Ipc: 7A 61K 38/13 A
2003-12-10	17Q	First examination report despatched	Effective date: 20031023
2005-12-02	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2006-01-18	18D	Application deemed to be withdrawn	Effective date: 20050719

Publication	Publication Date	Title
EP0956044A4 (en)	2005-01-05	USES OF CHEMOKINE RECEPTOR IN INHIBITION OF HIV-1 INFECTION
DE69129039D1 (en)	1998-04-09	ADJUSTABLE, DENTAL IMPLANT SYSTEM
DK469988A (en)	1988-08-22	sanitary napkins
DK0425026T3 (en)	1997-01-13	Disconnected sanitary napkin
BR9100633A (en)	1991-10-29	CURVED MONOMODAL ACTIVE FIBER OPTICAL AMPLIFIER
FR2757371B1 (en)	1999-03-26	ELASTIC DEVICE WITH LARGE ELONGATION CAPACITY FOR LIVE TISSUE EXTENSION
DE69106907D1 (en)	1995-03-09	Surgical gripping instrument.
NO944067D0 (en)	1994-10-26	Generally thin, pliable sanitary napkin with stiff center portion
DE69622535D1 (en)	2002-08-29	AMORPHE TETRAFLUORETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS
DE69031908D1 (en)	1998-02-12	Artificial retina
DE69009559D1 (en)	1994-07-14	Dental implant.
FI894541A7 (en)	1990-03-29	AIDS LAEKEMEDEL BASERADE PAO HIV PROTEASINHIBITORER.
FR2655534B1 (en)	1997-10-24	DENTAL IMPLANT.
ES2130114T3 (en)	1999-07-01	5,11-DIHIDRO-6H-DIPIRIDO (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINES AND ITS USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION.
DE69610322D1 (en)	2000-10-19	SUBSTITUTED TRIFLUOROSTYROL COPOLYMERS
FR2595364B1 (en)	1990-01-05	SILICONE COPOLYMER
ES2191075T3 (en)	2003-09-01	8-ARILALQUIL- AND 8-ARILHETEROALQUIL-5,11-DIHIDRO-6H-DIPIRIDO- (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINS AND THEIR USE IN THE PREVENTION OR TREATMENT OF INFECTIONS FOR HIV.
DE59010887D1 (en)	1999-12-09	Open-end spinning device
DE59003942D1 (en)	1994-02-03	Open-end spinning device.
EP0861082A4 (en)	2002-01-30	TREATMENT OF INSUFFICIENCY OF THE TISSUE MEMBRANE
EP0944394A4 (en)	2003-05-14	TREATMENT OF HIV INFECTION BY ACTION ON THE HOST CELL CYCLOPHILIN RECEPTOR
MA24332A1 (en)	1998-04-01	USE OF 1-HYDROXY-2- PYRIDONES FOR THE TREATMENT OF SKIN INFECTIONS
PT91936A (en)	1990-04-30	SANITA'S ASSEMBLY
DE59008072D1 (en)	1995-02-02	Open-end spinning device.
FR2740759B1 (en)	1997-12-12	SPECIFIC WASTE COLLECTOR, ESPECIALLY MEDICAL