EP0973866A4 - Adenovirus e1-complementing cell lines - Google Patents

Adenovirus e1-complementing cell lines

Info

Publication number
EP0973866A4
EP0973866A4 EP98908661A EP98908661A EP0973866A4 EP 0973866 A4 EP0973866 A4 EP 0973866A4 EP 98908661 A EP98908661 A EP 98908661A EP 98908661 A EP98908661 A EP 98908661A EP 0973866 A4 EP0973866 A4 EP 0973866A4
Authority
EP
European Patent Office
Prior art keywords
adenovirus
cell lines
complementing cell
complementing
lines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98908661A
Other languages
German (de)
French (fr)
Other versions
EP0973866A1 (en
Inventor
David Ayares
Ramon Alemany
Wei-Wei Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genstar Therapeutics Corp
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of EP0973866A1 publication Critical patent/EP0973866A1/en
Publication of EP0973866A4 publication Critical patent/EP0973866A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10345—Special targeting system for viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP98908661A 1997-03-04 1998-02-23 Adenovirus e1-complementing cell lines Withdrawn EP0973866A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US810039 1985-12-17
US81003997A 1997-03-04 1997-03-04
PCT/US1998/003473 WO1998039411A1 (en) 1997-03-04 1998-02-23 Adenovirus e1-complementing cell lines

Publications (2)

Publication Number Publication Date
EP0973866A1 EP0973866A1 (en) 2000-01-26
EP0973866A4 true EP0973866A4 (en) 2000-04-19

Family

ID=25202818

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98908661A Withdrawn EP0973866A4 (en) 1997-03-04 1998-02-23 Adenovirus e1-complementing cell lines

Country Status (4)

Country Link
EP (1) EP0973866A4 (en)
JP (1) JP2000509614A (en)
CA (1) CA2283253A1 (en)
WO (1) WO1998039411A1 (en)

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US7297680B2 (en) 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
US6855544B1 (en) 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
US7604960B2 (en) 1999-04-15 2009-10-20 Crucell Holland B.V. Transient protein expression methods
US8236561B2 (en) 1999-04-15 2012-08-07 Crucell Holland B.V. Efficient production of IgA in recombinant mammalian cells
US7192759B1 (en) 1999-11-26 2007-03-20 Crucell Holland B.V. Production of vaccines
US7521220B2 (en) 1999-11-26 2009-04-21 Crucell Holland B.V. Production of vaccines
US7527961B2 (en) 1999-11-26 2009-05-05 Crucell Holland B.V. Production of vaccines
PT1465987E (en) 2001-12-07 2008-04-15 Crucell Holland Bv Production of viruses, viral isolates and vaccines
ATE354645T1 (en) 2002-12-20 2007-03-15 Chromagenics Bv MEANS AND METHODS FOR PRODUCING A PROTEIN THROUGH CHROMATIN OPENERS WHICH CAN MAKE CHROMATIN MORE ACCESSIBLE TO TRANSCRIPTION FACTORS
WO2004099396A1 (en) 2003-05-09 2004-11-18 Crucell Holland B.V. Cultures of e1-immortalized cells and processes for culturing the same to increase product yields therefrom
US20070207461A1 (en) 2004-02-23 2007-09-06 Crucell Holland B.V. Virus Purification Methods
WO2005123918A1 (en) * 2004-06-22 2005-12-29 Tokai University Educational System Expression vector capable of regulating the induction of foreign gene expression
ES2384391T3 (en) 2004-11-08 2012-07-04 Chromagenics B.V. Selection of host cells that express protein at high levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
KR101271884B1 (en) 2004-11-08 2013-06-05 크로마제닉스 비.브이. Selection of host cells expressing protein at high levels
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
CA2602944C (en) 2005-04-11 2015-08-11 Crucell Holland B.V. Virus purification using ultrafiltration
US10041049B2 (en) 2008-11-03 2018-08-07 Janssen Vaccines & Prevention B.V. Method for the production of adenoviral vectors
JP5393896B2 (en) 2009-10-15 2014-01-22 クルセル ホランド ベー ヴェー Method for purifying adenovirus particles
CA2777116C (en) 2009-10-15 2020-09-01 Crucell Holland B.V. Process for adenovirus purification from high cell density cultures
MX2012007936A (en) 2010-02-15 2012-11-22 Crucell Holland Bv Method for the production of ad26 adenoviral vectors.
SI2825640T1 (en) 2012-03-12 2016-08-31 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
US8932607B2 (en) 2012-03-12 2015-01-13 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
JP5805908B2 (en) 2012-03-22 2015-11-10 クルセル ホランド ベー ヴェー Vaccine against RSV
US9119813B2 (en) 2012-03-22 2015-09-01 Crucell Holland B.V. Vaccine against RSV
KR102236497B1 (en) 2013-04-25 2021-04-06 얀센 백신스 앤드 프리벤션 비.브이. Stabilized soluble prefusion rsv f polypeptides
CN105408348B (en) 2013-06-17 2021-07-06 扬森疫苗与预防公司 Stabilized soluble prefusion RSV F polypeptide
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JP6735288B2 (en) 2015-04-14 2020-08-05 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． Recombinant adenovirus expressing two transgenes with bidirectional promoters
EA039065B1 (en) 2015-07-07 2021-11-29 Янссен Вэксинс Энд Превеншн Б.В. Vaccine against rsv
US10457708B2 (en) 2015-07-07 2019-10-29 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
JP6470872B2 (en) 2015-08-20 2019-02-13 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． HPV18 vaccine for treatment
JP7233928B2 (en) 2016-04-05 2023-03-07 ヤンセン ファッシンズ アンド プリベンション ベーフェー Vaccine against RSV
IL262108B2 (en) 2016-04-05 2023-04-01 Janssen Vaccines Prevention B V Stabilized soluble pre-fusion rsv f proteins
JP7053491B2 (en) 2016-05-02 2022-04-12 ヤンセン ファッシンズ アンド プリベンション ベーフェー Therapeutic HPV vaccine combination
CN109311946A (en) 2016-05-30 2019-02-05 扬森疫苗与预防公司 Stabilized prefusion RSV F protein
RU2745500C2 (en) 2016-06-20 2021-03-25 Янссен Вэксинс Энд Превеншн Б.В. Efficient and balanced bidirectional promotor
WO2018011196A1 (en) 2016-07-14 2018-01-18 Janssen Vaccines & Prevention B.V. Hpv vaccines
US11034978B2 (en) 2017-02-09 2021-06-15 Janssen Vaccines & Prevention B.V. Potent and short promoter for expression of heterologous genes
CN110832072B (en) * 2017-04-21 2023-11-07 真基因太科公司 Cell line for producing non-replicating adenovirus and method for preparing said cell line
AU2018267971A1 (en) 2017-05-17 2019-11-07 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
SG11202001458SA (en) 2017-09-15 2020-03-30 Janssen Vaccines & Prevention Bv Method for the safe induction of immunity against rsv
WO2019086450A1 (en) 2017-10-31 2019-05-09 Janssen Vaccines & Prevention B.V. Adenovirus and uses thereof
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CN111372943B (en) 2017-10-31 2023-12-05 扬森疫苗与预防公司 Adenovirus and its uses
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JP2022532742A (en) 2019-05-15 2022-07-19 ヤンセン ファッシンズ アンド プリベンション ベーフェー Prophylactic treatment of respiratory syncytial virus infection with adenovirus-based vaccine
US20220372515A1 (en) 2019-10-03 2022-11-24 Janssen Vaccines & Prevention B.V. Adenovirus vectors and uses thereof
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US20230024133A1 (en) 2020-07-06 2023-01-26 Janssen Biotech, Inc. Prostate Neoantigens And Their Uses
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Citations (4)

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Publication number Priority date Publication date Assignee Title
WO1996022378A1 (en) * 1995-01-20 1996-07-25 Rhone-Poulenc Rorer S.A. Cells for the production of recombinant adenoviruses
WO1996040955A1 (en) * 1995-06-07 1996-12-19 Graham Frank L Adenovirus vectors for gene therapy
WO1997000326A1 (en) * 1995-06-15 1997-01-03 Introgene B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
CA2177085A1 (en) * 1996-04-26 1997-10-27 National Research Council Of Canada Adenovirus e1-complementing cell lines

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
ATE336587T1 (en) * 1994-06-10 2006-09-15 Genvec Inc ADENOVIRUS VECTOR SYSTEMS AND CELL LINES

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022378A1 (en) * 1995-01-20 1996-07-25 Rhone-Poulenc Rorer S.A. Cells for the production of recombinant adenoviruses
WO1996040955A1 (en) * 1995-06-07 1996-12-19 Graham Frank L Adenovirus vectors for gene therapy
WO1997000326A1 (en) * 1995-06-15 1997-01-03 Introgene B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
CA2177085A1 (en) * 1996-04-26 1997-10-27 National Research Council Of Canada Adenovirus e1-complementing cell lines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199821, Derwent World Patents Index; Class B04, AN 1998-231229, XP002130856 *
RITTNER K ET AL.,: "Conditional repression of the E2 transcription unit in E1-E3-deleted adenovirus vectors is correlated with a strong reduction in viral DNA replication and late gene expression in vitro.", JOURNAL OF VIROLOGY, vol. 71, no. 4, April 1997 (1997-04-01), pages 3307-3311, XP002130911 *
See also references of WO9839411A1 *

Also Published As

Publication number Publication date
EP0973866A1 (en) 2000-01-26
WO1998039411A1 (en) 1998-09-11
JP2000509614A (en) 2000-08-02
CA2283253A1 (en) 1998-09-11

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